Clinical trials: Hydrocortisone, completed
Sleep, Mood
Tryptophan Supplementation to Improve Night Shift Workers' Health
This randomized cross-over double-blinded trial aims to investigate the health effect of oral l-tryptophan supplementation on workers who rotate night shift work, and to examine the influences of different frequencies and timings…
- Conditions
- Sleep, Mood, Burnout, Melatonin Deficiency
- Trial name
- NCT04505800
- Testing
- Tryptophan supplement, Maltose
- Where
- Taiwan
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- National Yang Ming Chiao Tung University
Hemodynamic Measure, Cognitive Performance in Healthy Volunteers
Assessing the Impact of High Theacrine Doses on Hemodynamic Measures
This project measured physiological and cognitive variables to determine the effectiveness of Theacrine (TCR) as a stimulant at doses greater than those previously tested.
- Trial name
- NCT07376564
- Testing
- Low dose theacrine, Medium dose theacrine, High dose theacrine
- Where
- United States
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Titch Madzima
Pregnancy Loss, Anxiety
EFT and Music on Psychological Development, Well-Being Status and Cortisol Level in Pregnant Women
Emotional freedom technique and music were applied to pregnant women who experienced prenatal loss. Emotional freedom technique group, music group and control groups each consisted of 53 pregnant women.
- Trial name
- EFT (NCT05344144)
- Testing
- Emotional Freedom Technique, Music
- Where
- Turkey (Türkiye)
- Volunteers
- 159 people, healthy volunteers welcome
- Sponsor
- Kahramanmaras Sutcu Imam University
Anxiety Disorder, Depression
Minocycline Hydrochloride in Reducing Chemotherapy Induced Depression and Anxiety in Patients With Stage I-III Breast Cancer
This randomized clinical trial studies how well minocycline hydrochloride works in reducing chemotherapy induced depression and anxiety in patients with stage I-III breast cancer.
- Conditions
- Anxiety Disorder, Depression, Recurrent Breast Cancer, Stage IA Breast Cancer
- Trial name
- NCT02203552
- Testing
- minocycline hydrochloride, laboratory biomarker analysis, Questionnaire administration
- Where
- United States
- Volunteers
- 56 people
- Sponsor
- Ohio State University Comprehensive Cancer Center
Infant, Newborn, Hypotension
Hypotension in Neonates
This observational study collects information on the current incidence and management of hypotension in babies born at term or late preterm that are admitted to Neonatal Intensive Care Units (NICUs) within the Neonatal Research…
- Conditions
- Infant, Newborn, Hypotension, Blood Pressure
- Trial name
- NCT00882284
- Where
- 17 sites in United States
- Volunteers
- 820 people
- Sponsor
- NICHD Neonatal Research Network
Psoriasis
Efficacy and Safety of Etanercept 50 mg Once Weekly Plus As Needed Topical Agent in Moderate to Severe Plaque Psoriasis
To estimate the difference in effectiveness between treatment with etanercept 50 mg twice weekly (BIW) and treatment with etanercept 50 mg once weekly (QW) plus an as needed (PRN) topical agent for 12 weeks in adults with…
- Trial name
- REFINE (NCT01313221)
- Testing
- etanercept, Topical agents
- Where
- 24 sites in Canada
- Volunteers
- 310 people
- Sponsor
- Amgen
Anorexia Nervosa
Re-nutrition in Severe Anorexia Nervosa
In anorexia nervosa (AN) it still remains to be clarified, which psychiatric symptoms are the direct consequence of malnutrition and adaptation to starvation and which are not.
- Trial name
- RESAN (NCT02502617)
- Testing
- medical nutrition
- Where
- 2 sites in Denmark
- Volunteers
- 36 people
- Sponsor
- René Klinkby Støving
Prostatic Neoplasms, Metastatic Castration-Resistant Prostate Cancer
A Study of Opevesostat (MK-5684) in China Participants With Metastatic Castration-Resistant Prostate Cancer (mCRPC) (MK-5684-001)
The primary objectives of this study are to evaluate the safety and tolerability of opevesostat in the treatment of male Chinese participants with metastatic castration-resistant prostate cancer (mCRPC) and to characterize the…
- Trial name
- NCT06136598
- Testing
- Opevesostat, Dexamethasone, Fludrocortisone
- Where
- 3 sites in China
- Volunteers
- 14 people
- Sponsor
- Merck Sharp & Dohme LLC
Esophageal Stenosis Acquired
Mixed Gel of Hydrocortisone and Aluminium Phosphate Preventing Endoscopic Submucosal Dissection Postoperative Stenosis for Patients With Large Esophageal Carcinoma
Endoscopic submucosal dissection as the fastest growing endoscopic treatment technology in the past decade has been widely used in the treatment of early esophageal cancer and gastric cancer without local lymph node metastasis.
- Trial name
- NCT03165344
- Testing
- Hydrocortisone sodium succinate mixed with Aluminium Phosphate gel (route of administration), Triamcinolone Acetonide (route of administration), Prednisone (route of administration)
- Where
- China
- Volunteers
- 66 people
- Sponsor
- Peking University Third Hospital
Congenital Adrenal Hyperplasia, 21-Hydroxylase Deficiency
Comparison of Two Forms of Hydrocortisone in Patients With Congenital Adrenal Hyperplasia
This study will test a new, extended release form of hydrocortisone called Chronocort in patients with congenital adrenal hyperplasia (CAH).
- Conditions
- Congenital Adrenal Hyperplasia, 21-Hydroxylase Deficiency, Adrenogenital Syndrome
- Trial name
- NCT00519818
- Testing
- Chronocort, Cortef
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Neurocrine UK Limited
Atopic, Dermatitis
Tacrolimus Versus Hydrocortisone in Atopic Dermatitis
Atopic dermatitis (AD) is a very common inflammatory, genetic skin disorder that occurs more frequently in children. Its exact etiology is not known but it is characterized by pruritic skin reactions with elevation in the levels…
- Trial name
- NCT05324618
- Testing
- Tacrolimus, Hydrocortisone
- Where
- Egypt
- Volunteers
- 200 people
- Sponsor
- Ain Shams University
Resistance Training, Sports Nutrition
Effects of Three Carbohydrate Beverages on Resistance Training Performance
This randomized, triple-blinded, counterbalanced crossover trial compared three carbohydrate beverages that provided the same amount of carbohydrate (30 g) but differed in carbohydrate source: dextrose, maltodextrin, and highly…
- Conditions
- Resistance Training, Sports Nutrition, Dietary Carbohydrates
- Trial name
- NCT07874776
- Testing
- Dextrose, Maltodextrin, Highly Branched Cyclic Dextrin
- Where
- Turkey (Türkiye)
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Istanbul Gelisim University
Depressive Disorder
The Antidepressant Effect of Repetitive Transcranial Magnetic Stimulation (rTMS)Compared to ECT
The aim of the present study is to compare the antidepressant effect of electroconvulsive therapy ( ECT) with that of low frequency repetitive transcranial magnetic stimulation of the right prefrontal cortex.
- Trial name
- NCT00299403
- Testing
- Right prefrontal lowfrequency ( 1 hz) rTMS., Electroconvulsive therapy (ECT)
- Where
- Denmark
- Volunteers
- 60 people
- Sponsor
- University of Aarhus
Stress Reaction, Behavior, Social
The Effects of Therapy Dogs on Child Biology and Behavior
The objective of this study is to apply a rigorous experimental design to test whether children's interactions with therapy dogs increase immediate prosocial behavior and reduce immediate biological response to stress.
- Trial name
- NCT03949569
- Testing
- Therapy Dog, Stuffed Toy Dog, 5 Minute Puppy Video
- Where
- United States
- Volunteers
- 188 people, healthy volunteers welcome
- Sponsor
- University of Chicago
Infant, Newborn, Diseases, Cardiovascular Insufficiency
Hydrocortisone for Term Hypotension
This trial will evaluate the effects of a 7-day course of hydrocortisone therapy on short-term morbidity, cardiovascular function, long-term neurodevelopment, and mortality in critically ill, term and late preterm infants…
- Trial name
- NCT01954056
- Testing
- Hydrocortisone
- Where
- 18 sites in United States
- Volunteers
- 12 people
- Sponsor
- NICHD Neonatal Research Network
Leukemia
Induction Intensification in Treating Infants With Newly Diagnosed Acute Lymphoblastic Leukemia
RATIONALE: Drugs used in chemotherapy work in different ways to stop cancer cells from dividing so they stop growing or die. Combining more than one chemotherapy drug and giving them as induction intensification may kill more…
- Trial name
- NCT00002756
- Testing
- filgrastim, asparaginase, cyclophosphamide
- Where
- 140 sites in United States, Australia and 2 more
- Volunteers
- 221 people
- Sponsor
- Children's Oncology Group
Posttraumatic Stress Disorder
Neural and Pharmacological Correlates of Intrusions in Patients With Posttraumatic Stress Disorder
There is evidence that glucocorticoids have an impact on intrusive memories in patients with posttraumatic stress disorder (PTSD).
- Trial name
- NCT01108133
- Testing
- 10 mg HydrocortisoneHöchst, Dexamethasone
- Where
- Germany
- Volunteers
- 13 people
- Sponsor
- Central Institute of Mental Health, Mannheim
Abdominal Neoplasm, Colonic Neoplasm
Treatment of Peritoneal Cancer With Surgery, Perfused Heated Cisplatin and Chemotherapy
This study will test the effectiveness of an experimental treatment for peritoneal cancer involving surgical removal of the tumor, perfusion of the abdomen during surgery with a heated solution of the drug cisplatin, and…
- Conditions
- Abdominal Neoplasm, Colonic Neoplasm, Mesothelioma, Peritoneal Neoplasm
- Trial name
- NCT00004547
- Testing
- Surgery, Continuous hyperthermic peritoneal perfusion (CHPP) with Cisplatin, Postoperative dwell with paclitaxel and 5-FU
- Where
- United States
- Volunteers
- 188 people
- Sponsor
- National Cancer Institute (NCI)
Cytochrome P450 Oxidoreductase Deficiency, Hypertension
Investigation of the Etiology of Hypertension and Endothelial Damage in Patients With Cytochrome P450 Oxidoreductase Deficiency
This study investigates the etiology of hypertension and endothelial damage in patients with Cytochrome P450 Oxidoreductase (POR) deficiency.
- Conditions
- Cytochrome P450 Oxidoreductase Deficiency, Hypertension, Endothelial Dysfunction, Congenital Adrenal Hyperplasia
- Trial name
- PORENDO (NCT06756620)
- Where
- Turkey (Türkiye)
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Ozge Bayrak Demirel
Bipolar Disorder
Clinical Trial of Mifepristone for Bipolar Depression
Bipolar Depression is a severe illness with high rates of psychiatric comorbidity and increased mortality related to suicide and medical illness.
- Trial name
- NCT00043654
- Testing
- Mifepristone
- Where
- United States
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- National Institute of Mental Health (NIMH)