Clinical trials: Ketorolac
Shoulder Arthropathy, Shoulder Pain
Opioid-Free Pain Protocol After Shoulder Arthroplasty
This randomized, single blinded, clinical trial aims to investigate the efficacy of a multimodal pain control regimen for shoulder arthroplasty.
- Trial name
- NCT05488847
- Testing
- Celecoxib, Pregabalin, Tramadol
- Where
- United States
- Volunteers
- 83 people, healthy volunteers welcome
- Sponsor
- Henry Ford Health System
Sedation and Analgesia Management in Patients Undergoing Flexible Bronchoscopy
Midazolam Alone Versus Midazolam With Ketorolac for Sedation During Flexible Bronchoscopy.
Flexible bronchoscopy has evolved into a vital diagnostic and therapeutic intervention in respiratory medicine due to its frequent and diverse applications.
- Trial name
- NCT07352059
- Testing
- Midazolam Alone, Midazolam + ketorolac
- Volunteers
- 50 people
- Sponsor
- SYED HAIDER ALI
Headache, Migraine
Intranasal Ketorolac Trial
The purpose of this study is to determine if intranasal (IN) Ketorolac in combination with oral Prochlorperazine and Diphenhydramine is non-inferior to current migraine management which involves use of intravenous (IV) Ketorolac…
- Trial name
- NCT06083571
- Testing
- Ketorolac, Prochlorperazine, Diphenhydramine
- Where
- United States
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Acute Pancreatitis
Initial Pain Management in Pediatric Pancreatitis: Opioid vs. Non-Opioid
This will be a phase 2, single-center, unblinded randomized controlled pilot trial of two arms comparing opioid-sparing analgesia to the current Boston Children's Hospital institutional practice which has been reported to…
- Trial name
- PATIENCE (NCT04291599)
- Testing
- Ketorolac, Opioid
- Where
- United States
- Volunteers
- 23 people
- Sponsor
- Boston Children's Hospital
Pain, Digital Block
Comparison of Intranasal Ketorolac and Intranasal Ketamine in Digital Nerve Block Pain
This study aims to compare the analgesic effectiveness and side effects of intranasal ketorolac versus intranasal ketamine for reducing pain prior to digital nerve block procedures in patients with finger injuries in emergency…
- Trial name
- NCT07305883
- Testing
- Intranasal Ketorolac Tromethamine, Intranasal ketamine
- Volunteers
- 64 people
- Sponsor
- Tehran University of Medical Sciences
Kidney Calculi, Ureteral Calculi
Study of Ketorolac Versus Opioid for Pain After Endoscopy
A double blind randomized controlled trial designed to compare pain control and safety with ketorolac and oxycodone in the post-operative setting for patients undergoing ureteroscopy for treatment of urinary stones.
- Trial name
- SKOPE (NCT03888144)
- Testing
- Oxycodone, Ketorolac
- Where
- United States
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- The Cleveland Clinic
Ureteral Stent Placement, Kidney Stone
NSAIDs Stent Study
This is a pilot study to (1) evaluate the effect of Ketorolac on inflammatory response and its impact on stent related symptoms in patients undergoing stent placement procedure and (2) assess feasibility of recruitment…
- Trial name
- NCT03638999
- Testing
- Ketorolac Trometamol 30Mg/1mL Injection, Normal saline
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- Washington University School of Medicine
Lumbar Spinal Fusion
Ketorolac Effects on Post-operative Pain and Lumbar Fusion
A double blind prospective randomized trial of IV ketorolac vs. placebo in management of patients undergoing lumbar one or two level spinal fusions.
- Trial name
- NCT06513208
- Testing
- Ketorolac Tromethamine
- Where
- United States
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- University of Maryland St. Joseph Medical Center
Infertility (IVF Patients), Infertility Treatment
Ketorolac Use and Fresh Embryo Transfer Outcomes
Ketorolac is a medication often used to relieve pain after surgery. In the past, infertility doctors have been cautious about using ketorolac after egg retrieval for patients planning a fresh embryo transfer (usually done 5 days…
- Conditions
- Infertility (IVF Patients), Infertility Treatment, Post-op Pain, Fresh Embryo Transfer
- Trial name
- NCT07185724
- Testing
- Ketorolac 30 mg IV
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Jessica D. Kresowik
Postoperative Pain
Comparing Intramuscular Fentanyl and Ketorolac With Nerve of Arnold (NOA) Block for Bilateral Myringotomy
Background: Bilateral myringotomy with tympanostomy tube (BMT) placement is one of the most common pediatric surgical procedures. Despite its brief duration, many children experience significant postoperative pain.
- Trial name
- NOA (NCT07276906)
- Testing
- Fentanyl, Ketorolac, Nerve of Arnold Block
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- University of South Alabama
Postoperative Pain Control in Surgical Neonates
The Use of Ketorolac in Surgical Neonates
The general purpose of this study is to characterize the safety profile of ketorolac in infants age 0-3 months. Our hypothesis is that ketorolac is safe in neonates, and effective in controlling pain with less narcotic…
- Trial name
- NCT01667120
- Testing
- Ketorolac
- Where
- United States
- Sponsor
- Nationwide Children's Hospital
ACL Surgery, Pain Management
Efficacy of Methylprednisolone for Pain Control After ACL Repair
Opioids are commonly used after orthopedic surgery for pain control but have been shown to increase complications, surgeries, readmissions, and risk for opioid use disorder.
- Trial name
- NCT07158476
- Testing
- Meloxicam 15 mg, Medrol 4 MG Oral Tablet Includes Medrol Dosepak, Gabapentin 300 mg
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- St. Louis University
Musculoskeletal Pain, Analgesia
Intramuscular Ketorolac at Two Single-Dose Regimens
The purpose of this study was to evaluate a single 15 mg intramuscular (IM) dose of ketorolac for analgesic non-inferiority versus a single 60 mg IM dose for the treatment of acute MSK pain in a military emergency department (ED)…
- Conditions
- Musculoskeletal Pain, Analgesia, Adverse Event
- Trial name
- NCT04763876
- Testing
- Ketorolac Injection 15 mg, Ketorolac Injection 60 mg
- Where
- United States
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- William Beaumont Army Medical Center
Adhesive Capsulitis of the Shoulder
Intra-articular Corticosteroids Are Widely Used for Adhesive Capsulitis, But Alternatives Are Required for Patients With Contraindications. Hyaluronic Acid (HA) and Ketorolac Have Shown Individual Benefits. However, Evidence on Their Combination Remains Limited.
This randomized, double-blind trial compared a single intra-articular injection of moderate-molecular-weight hyaluronic acid (HA) plus ketorolac with ketorolac alone in patients with adhesive capsulitis.
- Trial name
- NCT07183436
- Testing
- Intra-articular Hyaluronic Acid and Ketorolac, Intra-articular Ketorolac
- Where
- Thailand
- Volunteers
- 56 people
- Sponsor
- Mahidol University
Pain
Liposomal Bupivacaine (Exparel) for Postoperative Pain Control for Open and Laparoscopic Abdominal Hernia Repair
The purpose of this study is to learn how well Liposomal Bupivacaine (Exparel™) controls post-operative pain in patients undergoing both open and laparoscopic (minimally invasive) abdominal hernia repair surgery.
- Trial name
- NCT02128646
- Testing
- EXPAREL, Ketorolac, laparoscopic abdominal hernia repair
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- University of Kansas Medical Center
Pain Management
Effectiveness of Bupivacaine, Ketorolac, Ketamine, vs Bupivacaine Alone in Reducing Postoperative Pocket Pain
Bupivacaine is the most widely used local anesthetic agent across majority of the Cardiac Implantable Electronic device (CIED) implant procedures in the United States.
- Trial name
- NCT05575999
- Testing
- Bupivacaine alone OR Bupivacaine-Ketorolac-Ketamine (BKK) Combination
- Where
- 3 sites in United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Kansas City Heart Rhythm Research Foundation
Fentanyl, Ketorolac
Fentanyl Versus Ketorolac as an Adjuvant to Peribulbar Block for Anterior Segment Surgeries
This study aims to compare the efficacy of ketorolac and fentanyl as adjuvants to local anesthetics for anterior segment surgeries of the eye.
- Conditions
- Fentanyl, Ketorolac, Adjuvant, Peribulbar Block
- Trial name
- NCT07141589
- Testing
- Lidocaine + Bupivacaine + Hyaluronidase, Fentanyl + Lidocaine + Bupivacaine + Hyaluronidase, Ketorolac + Lidocaine + Bupivacaine + Hyaluronidase
- Where
- Egypt
- Volunteers
- 168 people
- Sponsor
- Cairo University
Other Acute Pain
An Efficacy and Safety Trial of Intranasal Ketorolac in Emergency Department Patients for the Treatment of Acute Pain
The purpose of this study is to determine the effectiveness, the safety, and the tolerability of intranasal ketorolac (Sprix) in relieving acute pain in adults ages 18-65 who come to the ED seeking care.
- Trial name
- Sprix (NCT01471639)
- Testing
- intranasal ketorolac
- Where
- United States
- Volunteers
- 37 people
- Sponsor
- The Cleveland Clinic
Pain, Postoperative, Osteoarthritis, Knee
Analgesic Efficacy of Pre-operative Dose of Ketorolac and Gabapentin
Evaluation of the analgesic efficacy of a pre-operative dose of ketorolac and gabapentin in reducing post-operative pain scores in patients undergoing TKA
- Trial name
- NCT07047040
- Testing
- Ketorolac Tromethamine 30 MG/ML Prefilled Syringe, Gabapentin, Empty Medication Capsules
- Where
- Egypt
- Volunteers
- 86 people
- Sponsor
- Assiut University
Degenerative Lumbar Spinal Stenosis, Degenerative Disc Disease
Effect of RECK in Posterior Spinal Fusion
"RECK" is a combination of local anesthesia medications, used for the purpose of pain control. RECK is an acronym which stands for Ropivacaine, Epinephrine, Clonidine, and Ketorolac.
- Conditions
- Degenerative Lumbar Spinal Stenosis, Degenerative Disc Disease, Degenerative Spondylolisthesis, Degenerative Disease
- Trial name
- NCT06447194
- Testing
- Ropivacaine, Epinephrine, Clonidine, and Ketorolac Injection Cocktail
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Maryland, Baltimore