Clinical trials: Manual therapy
Chronic Low Back Pain
Effects of a Myofascial Technique on Biomechanical Properties of the Lumbar Myofascia of Chronic Low Back Pain Adults
Non-specific low back pain is a worldwide health issue that remains poorly understood. Some authors have shown that the thoracolumbar fascia of low back pain adults presents changes in biomechanical properties.
- Trial name
- NCT04830566
- Testing
- Myofascial release technique, Simulated Myofascial Release technique
- Where
- Canada
- Volunteers
- 49 people
- Sponsor
- Université de Sherbrooke
Postpolio Syndrome
Effectiveness of Transcranial Magnetic Stimulation Treatment in Patients Diagnosed With Postpolio Syndrome
This randomized, double-blind, sham-controlled trial evaluated the effects of low-frequency repetitive transcranial magnetic stimulation (rTMS) over the primary motor cortex on walking capacity, fatigue, post-polio-related…
- Trial name
- NCT06926270
- Testing
- Repetitive transcranial magnetic stimulation (rTMS), Individualized home exercise program
- Where
- Turkey (Türkiye)
- Volunteers
- 28 people
- Sponsor
- Ege University
Radiation-Induced Fibrosis in Patients With Head and Neck Cancer
The Evaluation of Manual Therapy for the Prevention of Radiation-Induced Fibrosis in Patients With Head and Neck Cancer
The subjects in this study are the patients with head and neck cancer after completion of the radiotherapy. Radiation-induced fibrosis is inevitable and there is no effective treatment to prevent it.
- Trial name
- NCT04850170
- Testing
- manual therapy, Speech therapy
- Where
- Taiwan
- Volunteers
- 70 people
- Sponsor
- Chang Gung Memorial Hospital
Opiate Addiction
Models of Screening, Brief Intervention With a Facilitated Referral to Treatment (SBIRT) for Opioid Patients in the Emergency Department
Patients with heroin and prescription opioid dependence are at increased risk for adverse health consequences and often utilize the Emergency Department (ED) as their source of medical care.
- Trial name
- NCT00913770
- Testing
- Brief Negotiation Interview (BNI), Buprenorphine Initiation
- Where
- 2 sites in United States
- Volunteers
- 329 people
- Sponsor
- Yale University
Post Traumatic Stress Disorder
Reducing Posttraumatic Stress Disorder (PTSD) Symptoms in First Responders and Frontline Health Care Workers
This study addresses PTSD symptoms in First Responders and Healthcare workers. Specifically, it tests whether a brief PTSD treatment (talk therapy) effectively treats PTSD when provided to First Responders and Healthcare workers…
- Trial name
- NCT05751473
- Testing
- Prolonged Exposure for Primary Care (PE-PC), EAP Treatment as Usual (TAU)
- Where
- 14 sites in United States
- Volunteers
- 410 people
- Sponsor
- University of Michigan
Low Back Pain, Chronic Low Back Pain
Evaluation of Stabilization Training With Biofeedback in Lumbosacral Spine Pain Syndrome
The aim of the study is to evaluate the effects of biofeedback-assisted stabilization training and conventional therapy on pain perception, balance, spinal mobility, functional performance, physical activity, stress level, and…
- Trial name
- NCT07463729
- Testing
- Standard Rehabilitation, Biofeedback Ultrasonography
- Where
- Poland
- Volunteers
- 110 people
- Sponsor
- University of Rzeszow
Addiction
Vocal Biomarkers of Craving
Addiction is a psychiatric disorder associated with craving, an unwanted, intense and persistent desire to use the substance/addictive behavior, leading to frequent relapses.
- Trial name
- IVOMOC (NCT07878624)
- Testing
- Cue reactivity paradigm, Ecological momentary assessment
- Where
- France
- Volunteers
- 120 people
- Sponsor
- University of Bordeaux
Cephalometric Analysis, Cephalometry
Comparison of Digital Analysis and Artificial Intelligence for Cephalometric Tracing
This study aims to evaluate the accuracy and reliability of artificial intelligence (AI)-based cephalometric analysis compared with digital manual tracing.
- Conditions
- Cephalometric Analysis, Cephalometry, Artificial Intelligence (AI), Artificial Intelligence (AI) in Diagnosis
- Trial name
- NCT07664488
- Testing
- Cephalometric Analysis
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- University of Pavia
Knee Osteoarthritis
Efficacy of High Power Laser Versus Low Level Laser in Ultrasonographic and Functional Outcomes in Patients With Knee Osteoarthritis
this study will be conducted to compare between high power laser and low-intensity laser on ultrasonographic and functional outcomes in patients with knee osteoarthritis
- Trial name
- OA (NCT06419569)
- Testing
- high power laser, low level laser, conventional physical therapy
- Volunteers
- 90 people
- Sponsor
- Cairo University
Neck Pain
Comparison of Isometric and Isotonic Strengthening Exercises in Chronic Neck Pain Patients.
Study will be a Randomized clinical trial to check the effects of isometric and isotonic strength training exercises on patients with chronic neck pain.
- Trial name
- NCT05865951
- Testing
- Isometric Exercises, Isotonic Exercises
- Where
- Pakistan
- Volunteers
- 22 people
- Sponsor
- Riphah International University
Co-Occurring Disorders, Homelessness
Maintaining Independence and Sobriety Through Systems Integration, Outreach, and Networking
This study seeks to implement wrap around services for Veterans suffering from co-occurring mental illness and substance use and who are homeless.
- Conditions
- Co-Occurring Disorders, Homelessness, Substance Abuse Disorder, Mental Illness
- Trial name
- MISSION-HPACT (NCT02942979)
- Where
- United States
- Volunteers
- 108 people
- Sponsor
- VA Office of Research and Development
Joint Diseases
Comparative Effectiveness of HVT and Bowen Technique in Patients of SI Joint Dysfunction With Upslipped Innominates
Sacroiliac joint dysfunction (SIJD) is a common musculoskeletal condition characterized by pain and impaired function in the lower back and pelvis region.
- Trial name
- NCT06404346
- Testing
- High Velocity Thrust, Bowen therapy
- Where
- Pakistan
- Volunteers
- 26 people
- Sponsor
- Superior University
Multiple Sclerosis
Who Benefits Most From Cognitive Rehabilitation for Multiple Sclerosis?
Over the last 20 years, there have been many studies investigating the efficacy of attention and memory rehabilitation for people with multiple sclerosis (MS) however, there appears to be a lack of conclusive evidence regarding…
- Trial name
- NCT05509426
- Testing
- Cognitive Rehabilitation
- Where
- United Kingdom
- Volunteers
- 36 people
- Sponsor
- University of Nottingham
Meibomian Gland Dysfunction (Disorder)
TearCare MGX™ System With and Without Warming Hold
TearCare is an office-based thermal therapeutic eyelid technology cleared by the US Food and Drug Administration for the treatment of evaporative dry eye disease due to meibomian gland dysfunction.
- Trial name
- XTEND (NCT07365735)
- Testing
- localized heat therapy
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- Sight Sciences, Inc.
Total Knee Replacement, Manipulation
Efficacy and Safety of Chuna Manual Treatment as an Adjunctive Therapy After Total Knee Arthroplasty: A Study Protocol for a Single-Center, Randomized, Assessor Blind, Parallel-Group Clinical Trial
Evaluate the efficacy and safety of Chuna treatment as an adjunctive therapy in patients with moderate pain following total knee replacement.
- Trial name
- NCT03625050
- Testing
- Chuna + Usual care(Celecoxib and esomeprazole), Usual care(Celecoxib and esomeprazole)
- Where
- South Korea
- Volunteers
- 22 people
- Sponsor
- Gachon University Gil Oriental Medical Hospital
Shoulder Tendinopathy, Shoulder Tendinitis
Electroacupuncture and Cupping for Shoulder Tendinitis
This study aims to evaluate the effectiveness of electroacupuncture combined with vacuum cupping therapy in treating simple periarthritis of the shoulder associated with the traditional medicine syndrome of Qi stagnation and…
- Trial name
- NCT07545785
- Testing
- Electroacupuncture, Vacuum Cupping Therapy
- Where
- 2 sites in Vietnam
- Volunteers
- 54 people
- Sponsor
- University of Medicine and Pharmacy at Ho Chi Minh City
Neck Pain
Effects of Autogenic and Reciprocal Inhibition, Muscle Energy Techniques in the Management of Mechanical Neck Pain
Neck pain is among the most common musculoskeletal disorders worldwide and is an important public health issue in terms of personal wellbeing.
- Trial name
- NCT03136250
- Testing
- Group A (Control Group - Static Stretching + Standard Treatment), Group B (Autogenic Inhibition - PIR + Standard treatment), Group C (Reciprocal Inhibition - RI + Standard treatment)
- Where
- Pakistan
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Foundation University Islamabad
Stroke
Effect of Segmental Muscle Vibration on Upper Extremity Functional Ability Post Stroke
Background and objective: Upper extremity functional impairments are common consequences post stroke. The aim of this study was to investigate the influence of Segmental muscle vibration (SMV) application along with supervised…
- Trial name
- NCT03419793
- Testing
- segmental vibration device, physical therapy exercises
- Volunteers
- 37 people
- Sponsor
- University of Rome Tor Vergata
Relapsed/Refractory Multiple Myeloma
A Study to Investigate Subcutaneous Isatuximab in Combination With Carfilzomib and Dexamethasone in Adult Participants With Relapsed and/or Refractory Multiple Myeloma
The main purpose of this study is to measure the efficacy (Myeloma response) of subcutaneous (SC) isatuximab treatment in combination with carfilzomib and dexamethasone in adult participants with RRMM having received 1 to 3 prior…
- Trial name
- IZALCO (NCT05704049)
- Testing
- Isatuximab, Carfilzomib, Dexamethasone
- Where
- 23 sites in Australia, Brazil and 5 more
- Volunteers
- 118 people
- Sponsor
- Sanofi
Back Pain
The Efficacy of Kinesio Taping in the Treatment of Nonspecific Acute Low Back Pain
The Purpose of the study was to examine the effect of KinesioTaping (KT) on disability, fear avoidance beliefs and pain intensity in patients with acute non-specific LBP.
- Trial name
- NCT04263740
- Testing
- Kinesio Taping, Traditional Physical therapy
- Volunteers
- 88 people
- Sponsor
- Rocky Mountain University of Health Professions
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