Clinical trials: Metronidazole
Surgical Site Infection, Colon Surgery
Gut Decolonisation With Neomycin/Metronidazole or Rifaximin Before Colon Surgery
The goal of this clinical trial is to find out if a gut cleaning using Rifaximin works as well as the usual treatment with Neomycin and Metronidazole to prevent infections after colon surgery.
- Conditions
- Surgical Site Infection, Colon Surgery, Surgical Site Infections
- Trial name
- NeoRiDe (NCT07180615)
- Testing
- Rifaximin (Xifaxan), Metronidazole, Neomycin Sulfate
- Where
- 4 sites in Switzerland
- Volunteers
- 458 people
- Sponsor
- Universität Luzern
Resilience, Psychological, Mental Well-being
Evaluating a Digital Intervention to Improve Resilience and Reduce Stress in Stanford Populations
High-achieving academic and entrepreneurial populations face elevated risks of chronic stress, anxiety, and burnout. These populations often underutilize mental health services due to stigma, time constraints, or accessibility…
- Trial name
- SIER-WONE (NCT07565571)
- Testing
- Intervention WONE App (full Version)
- Where
- United States
- Volunteers
- 260 people, healthy volunteers welcome
- Sponsor
- Stanford University
For Patients With Colorectal Cancer Liver Metastases Who Were Not Able to Curative Surgical Resection.Focused on the Treatment Effect With the Quintuple Method
Quintuple Method for Treatment of Multiple Refractory Colorectal Liver Metastases
The aim of this study is to explore the therapeutic effect of Quintuple method in the treatment of patients with multiple and refractory liver metastases from colorectal cancer.
- Trial name
- NCT05774964
- Testing
- Oxaliplatin, S1, Cetuximab
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Liaoning Cancer Hospital & Institute
Sleep Apnea, Obstructive
Evaluation of a Health Dashboard Intervention to Improve Engagement With CPAP Therapy in PAP-Naïve Patients: Project Neo
This is a prospective, open-label study to evaluate the effectiveness of providing a dashboard with merged health metrics of CPAP (continuous positive airway pressure/ PAP) usage, self-reported sleepiness, blood pressure (BP) and…
- Trial name
- NCT04912635
- Testing
- Neo App
- Where
- Australia
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- ResMed
Endovascular Infection, Bone and Joint Infection
Comparing Oral Versus Parenteral Antimicrobial Therapy
This is an investigator initiated multisite pragmatic randomized controlled trial designed to demonstrate equivalent effectiveness with improved safety of early transition from intravenous (IV) antimicrobial therapy to complex…
- Conditions
- Endovascular Infection, Bone and Joint Infection, Skin and Soft Tissue Infection, Pulmonary Infection
- Trial name
- COPAT (NCT05977868)
- Testing
- Amoxicillin, amoxicillin-clavulanate, cefadroxil, cefpodoxime, cefalexin, ciprofloxacin, delafloxacin, doxycycline, levofloxacin, linezolid, Ampicillin, ampicillin-sulbactam, cefazolin, cefepime, ceftaroline, ceftazidime, ceftazidime-avibactam, dalbavancin, daptomycin, ertapenem
- Where
- United States
- Volunteers
- 94 people
- Sponsor
- West Virginia University
Dysphagia
Standardizing Swallow Pressure Measurements
This study aims to directly compare and contrast swallowing pressure and impedance measurements obtained from two high-resolution manometry (HRM) systems: the Laborie LMT Pharyngeal System and the Medtronic ManoScan ESO HRM…
- Trial name
- NCT07475091
- Testing
- Laborie LMT Pharyngeal System (3.7 mm catheter), Medtronic ManoScan ESO HRM System (4.2 mm catheter)
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Aging
Active Video Game on Metabolic, Cardiovascular, and Psychological Metrics in Older Adults
The Xbox Kinect seems to be a good alternative for the older adults to perform physical activities at times that are typically associated with sedentary behaviors.
- Trial name
- NCT04352543
- Testing
- Active Video Game Exercise, Treadmill walking exercise, Sedentary Behavior
- Where
- Brazil
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Universidade Federal de Goias
IVF
Levofloxacin Plus Metronidazole Suppositories Versus Levofloxacin Co-administered with Metronidazole Tablets in Chronic Endometritis
This is a single randomised controlled trial. The investigators plan to randomise 800 participants to the levofloxacin plus metronidazole suppositories versus levofloxacin co-administered with metronidazole tablets for the…
- Trial name
- NCT06650540
- Testing
- Levofloxacin Plus Metronidazole Suppositories, Levofloxacin co-administered with Metronidazole tablets
- Where
- China
- Volunteers
- 800 people
- Sponsor
- Peking University Third Hospital
Diabetes Mellitus, Type 1, Continuous Glucose Measurement
Individualized Automatic Coaching Message for Glycemic Management and Depressive Symptom
This is a single-center, randomized, prospective, confirmatory study of efficacy of individualized automatic coaching message for glycemic management and depressive symptom in patients with type 1 diabetes.
- Trial name
- NCT06684678
- Testing
- individualized automatic coaching message for glycemic management and depressive symptom
- Where
- South Korea
- Volunteers
- 140 people
- Sponsor
- Samsung Medical Center
Oral Lichen Planus
Study of Metronidazole and Doxycycline to Treat Oral Lichen Planus and to Compare Their Efficacy With Each Other
Oral lichen planus (OLP) is a chronic inflammatory disorder which causes local irritation,discomfort and subsequent poor dentition and discomfort in eating .
- Trial name
- NCT00484250
- Testing
- metronidazole,doxycycline
- Where
- Iran
- Volunteers
- 20 people
- Sponsor
- Mashhad University of Medical Sciences
Persistence of Infection With Helicobacter Pylori
The Role of Cathepsin X in Infection With the Helicobacter Pylori
The immune response to Helicobacter pylori (Hp) importantly determines the pathogenesis of infection as well as the success of antibiotic eradication of the bacteria.
- Trial name
- NCT01137942
- Testing
- clarithromycin, metronidazole, proton pump inhibitor
- Where
- Slovenia
- Volunteers
- 14 people
- Sponsor
- University Medical Centre Ljubljana
H Pylori Infection
Prevalence of Asymptomatic H Pylori Infection Among Patients Undergoing PCI and Impact of Its Eradication on Occurrence of GIT Symptoms and Bleeding"
In the present study, the aim was to report the prevalence of positive H. pylori infection in an unselected population referred for coronary intervention and likely to required DAPT or DPI, also the study assessed impact of H.
- Trial name
- NCT07487142
- Testing
- BISMUTH TETRACYCLINE METRONIDAZOLE OMEPRAZOLE
- Where
- Egypt
- Volunteers
- 121 people
- Sponsor
- Beni-Suef University
Antibiotic, Bowel Cancer
Mechanical Bowel Preparation With or Without Oral Antibiotics for Colorectal Cancer Surgery
Investigation of the role of adding oral antibiotics to preoperative mechanical bowel preparation before colorectal surgery for cancer.
- Conditions
- Antibiotic, Bowel Cancer, Colorectal Cancer, Surgical Site Infection
- Trial name
- MECCA (NCT03563586)
- Testing
- Bowel Preparation plus antibiotics, Bowel Preparation
- Where
- Greece
- Volunteers
- 210 people
- Sponsor
- National and Kapodistrian University of Athens
Unconsciousness, Apnea, Postanesthetic
Race-Specific Propofol Titration to Effect for Procedural Sedation
Prospectively evaluate newly established guidelines and make clinicians aware of inter-racial difference in propofol sensitivity.
- Conditions
- Unconsciousness, Apnea, Postanesthetic, Sedative Overdose, Hypoxemia
- Trial name
- NCT03290859
- Testing
- Titrate propofol monotherapy infusion to effect
- Where
- United States
- Volunteers
- 2,780 people
- Sponsor
- University of Florida
Acute Appendicitis, Appendicitis Recurrent
Appendectomy Versus Conservative Treatment for Uncomplicated Acute Appendicitis
On September the 15th, 2015, Italian surgeons, radiologists and pathologists with a special interest and expertise in the diagnosis and management of Acute Appendicitis (AA), met up under the auspices of the Italian Society of…
- Conditions
- Acute Appendicitis, Appendicitis Recurrent, Appendectomy, Antibiotic Therapy
- Trial name
- ACTUAA (NCT03080103)
- Testing
- Laparoscopic or Open appendectomy, Antibiotic-first therapy
- Where
- 7 sites in Italy
- Volunteers
- 300 people
- Sponsor
- Mauro Podda
Helicobacter Pylori Infection
The Efficacy of Susceptibility Test -Driven Sequential Therapy as the Third Line Therapy for Refractory Helicobacter Pylori Infection
Background: Helicobacter pylori infection has been shown to be associated with the development of gastric cancer and peptic ulcer diseases. Eradication of H.
- Trial name
- NCT01032655
- Testing
- susceptibility test guided sequential therapy
- Where
- Taiwan
- Volunteers
- 134 people
- Sponsor
- National Taiwan University Hospital
Recurrent Lumbar Disc Herniation
The Prediction of Recurrence Lumbar Disc Herniation At L5-S1 Level Through Machine Learning Models Based on Endoscopic Discectomy Via the Interlaminar Approach
What Was the Study About? This study focused on improving the care of patients with a specific type of back problem called lumbar disc herniation at the L5-S1 level.
- Trial name
- NCT06833099
- Testing
- VAS Point and Imaging Examination
- Where
- China
- Volunteers
- 309 people
- Sponsor
- Jinyu Chen
Helicobacter Pylori Infection, Family History of Stomach Cancer
Comparison of 7-day PPI-based Standard Triple Therapy and 10-day Bismuth Quadruple Therapy for H. Pylori Eradication
In this randomized controlled trial, we investigate the effect of 10-day bismuth quadruple therapy in comparison with that of 7-day PPI-based standard triple as 1st line treatment for H. pylori.
- Trial name
- NCT02557932
- Testing
- Standard triple therapy, Bismuth quadruple therapy
- Where
- South Korea
- Volunteers
- 352 people, healthy volunteers welcome
- Sponsor
- National Cancer Center, Korea
H Pylori Infection
Genotypic Resistance Guided Therapy for Refractory H. Pylori Infection
The inviestigators aimed to compare the efficacy of genotypic resistance guided versus susceptibility testing guided therapy in the third line treatment for refractory H. pylori infection.
- Trial name
- NCT03555526
- Testing
- Esomeprazole 40mg, Amoxicillin, metronidazole
- Where
- Taiwan
- Volunteers
- 320 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Hidradenitis Suppurativa
Efficacy of an Adapted Antibiotherapy in Hurley Stage 2 Hidradenitis Suppurativa Patients
The study evaluates the efficacy of an adapted antibiotherapy in Hurley stage 2 active Hidradenitis Suppurativa patients versus tetracycline derivative
- Trial name
- ABCESS2 (NCT05821478)
- Where
- 4 sites in France
- Volunteers
- 92 people
- Sponsor
- Institut Pasteur
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