Clinical trials: Metronidazole
Intracranial Pressure, Intracranial Pressure Changes
CoMind Early Feasibility Study
The purpose of this research, which has been determined as non-significant risk by the central IRB overseeing the study, is to obtain information to help further develop a machine (a medical device) to measure the pressure around…
- Conditions
- Intracranial Pressure, Intracranial Pressure Changes, Traumatic Brain Injury, Intracerebral Hemorrhage
- Trial name
- CoMind EFS (NCT06368648)
- Where
- 17 sites in United States
- Volunteers
- 581 people
- Sponsor
- CoMind Technologies Limited
Chronic Lymphocytic Leukaemia (CLL)
CLL Empirical Antibiotic Regimen
The purpose of this study is to evaluate whether patients with previously untreated, early stage CLL respond to empirical broad spectrum antibiotics and therefore test the hypothesis that occult bacterial infections are involved…
- Trial name
- CLEAR (NCT01279252)
- Testing
- metronidazole, clarithromycin, ciprofloxacin and lansoprazole
- Where
- United Kingdom
- Volunteers
- 71 people
- Sponsor
- King's College Hospital NHS Trust
Bacterial Vaginosis
Inflammation and Treatment of Bacterial Vaginosis Near Term
Most studies demonstrate that untreated bacterial vaginosis increases the rate of preterm birth. Despite this, there is no evidence that screening and treatment of asymptomatic bacterial vaginosis nor interpregnancy treatment of…
- Trial name
- NCT00720291
- Testing
- Metronidazole
- Where
- United States
- Volunteers
- 59 people
- Sponsor
- Medical University of South Carolina
Bacterial Vaginosis, Candida Vaginal
The LISA (Lactoferrin InStead of Antibiotics/Antifungals) Feasibility Study
Three-quarters of women have bacterial vaginosis (BV) or vaginal thrush/candida yeast infection at least once during their lifetime. Symptoms can include abnormal vaginal discharge, soreness, itching and an unpleasant smell.
- Trial name
- LISA (NCT05434104)
- Testing
- Vaginal lactoferrin, Usual care
- Where
- 2 sites in United Kingdom
- Volunteers
- 114 people
- Sponsor
- Guy's and St Thomas' NHS Foundation Trust
ACL Injuries
Plyometric Training With or Without Hamstring Strengthening for Preventing ACL Injuries in Female Amateur Athletes
This randomized controlled trial explored the effect of plyometric training with or without hamstring strengthening in preventing anterior cruciate ligament (ACL) injuries among female amateur athletes aged 18 to 30.
- Trial name
- NCT07047833
- Testing
- Plyometric Training with Hamstring Strengthening, Plyometric Training Only
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- University of Lahore
Periapical Abscess
Comparison of Triple Antibiotic Paste With Combination of Chitosan and Calcium Hydroxide as a Root Canal Disinfectant
Investigators observed the clinical and radiographic healing of periapical lesion using Chitosan mixed with calcium hydroxide and compared it with triple antibiotic paste when used as intracanal medicament in 3months, 6 months…
- Trial name
- NCT04319575
- Testing
- root canal treatment and intracanal medicament
- Where
- India
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Dr. D. Y. Patil Dental College & Hospital
Hysterectomy, Cellulitis
Prevention of Vaginal Cellulitis or Vaginal Cuff Abscess After Laparoscopic Hysterectomy
Operative site infection remains the most common complication after performing a gynecological procedure, and has a great implication in the morbidity and mortality of patients.
- Conditions
- Hysterectomy, Cellulitis, Vaginosis, Abscess
- Trial name
- NCT03917134
- Testing
- cephalosporin + Metronidazole Vaginal
- Where
- 2 sites in Colombia
- Volunteers
- 600 people
- Sponsor
- CES University
Gastric Diffuse Large B-cell Lymphoma
First-line Antibiotic Therapy for Early-stage HP(+) Gastric Pure DLBCL
Aims: A nationwide study to prospectively validate 1. The complete histological and molecular remission rate for antibiotics as 1st-line therapy for early-stage Hp-positive gastric pure (de novo) DLBCL 2.
- Trial name
- NCT02388581
- Testing
- Lansoprazole, Amoxicillin, Clarithromycin, Metronidazole
- Where
- Taiwan
- Volunteers
- 30 people
- Sponsor
- National Health Research Institutes, Taiwan
Helicobacter Pylori Infection
Efficacies of HDDT With or Without Bismuth vs Amoxicillin-metronidazole BQT for First-line H Pylori Eradication
Up to know, three is few large-scale, randomized study prospectively and simultaneously comparing the efficacy, adverse effects and patient compliance of high-dose dual therapy (HDDT) with or without bismuth versus…
- Trial name
- NCT03897244
- Testing
- High-dose dual therapy (rabeprazole, amoxicillin), Bismuth High-dose dual therapy (rabeprazole, amoxicillin, tripotassium dicitrate bismuthate), Amoxicillin-Metronidazole Bismuth quadruple therapy
- Where
- Taiwan
- Volunteers
- 603 people
- Sponsor
- National Taiwan University Hospital
Dental Caries
Use of Antibacterial Cement in Infected Dentin
Dental materials with antibacterial properties can prevent the harmful effects caused by oral cariogenic bacteria. This double-blind controlled clinical trial evaluated the performance of antibacterial cement for sealing infected…
- Trial name
- AC (NCT01449136)
- Testing
- Antibacterial cement
- Where
- Brazil
- Volunteers
- 45 people
- Sponsor
- University of Pernambuco
Pharmacogenetic Testing
Pilot of Preemptive Pharmacogenetics in Medically Underserved Patients
This is a pragmatic clinical trial of 100 patients who self-identify as black or Latino. Patients with active prescriptions for at least 3 medications and a medication change within the past 6-months will be recruited from the…
- Trial name
- NCT04630093
- Testing
- Panel-based pharmacogenetic genotyping
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of Florida
Periodontitis
Metronidazole and Amoxicillin for the Treatment of Type 2 Diabetic Subjects With Periodontitis
Diabetes mellitus (DM) is a widely prevalent disease associated with several major systemic and oral complications, such as periodontitis.
- Trial name
- NCT02135952
- Testing
- SRP, MTZ+AMX
- Where
- Brazil
- Volunteers
- 58 people
- Sponsor
- University of Guarulhos
Eye-tracking
EYE-TRAC Advance: Technology Verification (ETA-TV) Cohort 2
This is a prospective multi-center cohort feasibility and exploratory study.
- Trial name
- ETA-TV (NCT02877732)
- Testing
- EYE-SYNC eye-tracking, SCAT-3 subtests, DEM
- Where
- 4 sites in United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Stanford University
Surgical Education and Skill Acquisition
SOAR: Surgery Objective Analysis and Review
The purpose of this pilot study is to determine the feasibility and usability of a surgical software training platform called the SOAR Webapp that will allow Johns Hopkins surgical trainees to receive rapid qualitative and…
- Trial name
- SOAR (NCT07344155)
- Testing
- SOAR Webapp-Based Video Review and Feedback
- Volunteers
- healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Anemia, Iron-Deficiency, Helicobacter Pylori
Helicobacter Pylori and Iron Deficiency: Prevalence of Association and Effect of Therapy
Iron deficiency anemia (IDA) is a major health problem in children, effecting up to 20% of young children. Helicobacter pylori (HP) infection is also reported to be prevalent in children.
- Trial name
- NCT00475527
- Testing
- omeprazole,clarithromycin,amoxicillin (or metronidazole)
- Where
- Israel
- Sponsor
- Hadassah Medical Organization
Surgical Site Infection, Anastomotic Leak
Oral Antibiotic Prophylaxis in Colorectal Surgery
The investigators perform a case-control study to compare preparation before elective colorectal surgery. The first group is a prospective patient - registry in all patients with mechanical bowel preparation (MBP) and oral…
- Trial name
- ABCR (NCT03759886)
- Testing
- Paromomycin Sulfate Powder
- Where
- Germany
- Volunteers
- 100 people
- Sponsor
- University of Leipzig
Effect of Real-time Visual Feedback on Participant Compliance, Motivation, and Performance in Swimming
Real-time Feedback in Swimming: Workout Compliance and Swimming Performance Outcomes Using Smart Swim Goggles
In August of 2019 a Canadian company, Form Athletica Inc. (FORM), introduced a pair of Smart swimming goggles (FORM goggles) with a built-in see-through display.
- Trial name
- NCT06556212
- Testing
- Real-time feedback using smart swim goggles
- Where
- Canada
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- Simon Fraser University
Prostate Cancer
Enzalutamide in Combination With PSA-TRICOM in Patients With Non-Metastatic Castration Sensitive Prostate Cancer
Background: Enzalutamide is a well tolerated hormone therapy that is used to treat advanced prostate cancer. It is given to help kill cancer cells and limit cancer cell growth.
- Trial name
- NCT01875250
- Testing
- PROSTVAC-F (Fowlpox)/TRICOM, PROSTVAC-V (Vaccinia)/TRICOM, Enzalutamide (Xtandi)
- Where
- United States
- Volunteers
- 38 people
- Sponsor
- National Cancer Institute (NCI)
Stroke, Ischemic Heart Disease
Door-to-door Survey of Cardiovascular Health, Stroke and Ischemic Heart Disease in Atahualpa
The aim of the Atahualpa project is to evaluate the cardiovascular (CVH) status of the inhabitants of a rural village of coastal Ecuador as well as to determine the prevalence and retrospective incidence of stroke and ischemic…
- Trial name
- TAP (NCT01627600)
- Where
- 2 sites in Ecuador
- Volunteers
- 642 people, healthy volunteers welcome
- Sponsor
- Hospital Clínica Kennedy
Fear of Childbirth, Tocophobia
Digital Prenatal Education to Reduce Fear of Childbirth in Term Pregnancy
Many pregnant women feel afraid of giving birth. This fear is common and can affect how a woman experiences labour, the type of birth she has, and how she feels afterwards.
- Conditions
- Fear of Childbirth, Tocophobia, Pregnancy Related Anxiety
- Trial name
- FEARLESS-BIRTH (NCT07743502)
- Testing
- Web-based prenatal education platform
- Where
- Spain
- Volunteers
- 176 people, healthy volunteers welcome
- Sponsor
- Sergio Mies Padilla
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