Clinical trials: Morphine, completed
Morbid Obesity, Postoperative Pain
Patients-Controlled Epidural Analgesia After Gastric Bypass for Morbid Obesity Using Morphine-Levobupivacaine Regimens
Adequate postoperative analgesia can facilitate recovery following gastric bypass surgery for morbid obesity. The efficacy and safety of intravenous patient - controlled analgesia has been studied, but up to date no data are…
- Conditions
- Morbid Obesity, Postoperative Pain, Postoperative Bowel Function, Postoperative Ambulation
- Trial name
- NCT01249872
- Testing
- GROUP A : 0 mg MORPHINE-0.1% LEVOBUPIVACAINE, GROUP B : 1 mg MORPHINE- 0.1% LEVOBUPIVACAINE, GROUP C : 2 mg MORPHINE-0.1% LEVOBUPIVACAINE
- Where
- Greece
- Volunteers
- 96 people
- Sponsor
- University of Patras
Sleep Disorder, Sleep, Inadequate
Measuring Sleep Quality In Patients That Posterior Spinal Instrumentatıon Plannıng
Postoperative sleep disorders have serious problems with cognition, pain perception, sustained circadian rhythm, psychomotor function, metabolic function, catabolic responses, and continuity.
- Conditions
- Sleep Disorder, Sleep, Inadequate, Total ıntravenous Anesthesia, Inhalation Anesthesia
- Trial name
- NCT06269328
- Testing
- Total ıntravenous anesthesia with propofol and remifentanil for anesthetic maintenance, Inhalation anesthesia with sevoflurane for anesthetic maintenance
- Where
- Turkey (Türkiye)
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Uludag University
Acute Pain
A Randomized, Double-blind Comparison of Morphine and Sufentanil for Prehospital Traumatic Severe Acute Pain
Obtaining high-quality analgesia in prehospital patients with severe pain is an important treatment objective for medical team. Opioids are recognized as the treatment of choice for relief of severe acute pain.
- Trial name
- NCT00656773
- Testing
- Sufentanil, Morphine
- Where
- France
- Volunteers
- 108 people
- Sponsor
- University Hospital, Toulouse
Pain
Study of Embeda (Kadian NT, ALO-01) in Subjects With Chronic Moderate to Severe Nonmalignant Pain
Open-Label, Safety Study to evaluate the long-term safety of Kadian NT (ALO-01) administered for up to 12 months.
- Trial name
- NCT00415597
- Testing
- ALO-01 (Morphine Sulfate Plus Naltrexone Hydrochloride ER)
- Where
- 58 sites in United States
- Volunteers
- 467 people
- Sponsor
- Pfizer
Temporomandibular Disorder
Efficacy of Naproxen-codeine, Naproxen+Dexamethasone, and Naproxen on Myofascial Pain
Temporomandibular disorders (TMDs) are one of the most common muco-skeletal disorders, seen in the dental clinics. Many factors work together to initiate or aggravate the condition, so it is a multifactorial disorder.
- Trial name
- NCT04066426
- Testing
- naproxen sodium+codeine phosphate, naproxen sodium+dexamethasone, naproxen sodium, paracetamol
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people
- Sponsor
- Yuzuncu Yil University
Unstable Angina Pectoris
Influence of Metoclopramide on Ticagrelor Pharmacokinetics and Pharmacodynamics in Patients With Unstable Angina Pectoris on Concomitant Treatment With Morphine
The purpose of this study is to evaluate differences in the pharmacokinetics and pharmacodynamics of ticagrelor and its active metabolite between patients who received ticagrelor and morphine followed by metoclopramide versus…
- Trial name
- NCT02939235
- Testing
- Crushed ticagrelor followed by morphine, Crushed ticagrelor, morphine,metoclopramide
- Where
- Poland
- Volunteers
- 32 people
- Sponsor
- Collegium Medicum w Bydgoszczy
Post Operative Pain
Bunionectomy Trial With GRT6005
The purpose of the trial is to determine whether the new centrally acting analgesic is effective in comparison to placebo and an active comparator (morphine).
- Trial name
- NCT00872885
- Testing
- GRT6005, Morphine
- Where
- United States
- Volunteers
- 258 people
- Sponsor
- Tris Pharma, Inc.
Schizophrenia, Schizoaffective Disorder
Effectiveness of Motivation Skills Training (MST)
This study will take place at four outpatient clinics serving adults with serious mental illness. Informed consent will be obtained from N=80 individuals with a Diagnostic and Statistical Manual of Mental Illnesses (DSM)-5…
- Trial name
- MST (NCT05805397)
- Testing
- Motivation Skills Training, Healthy Behaviors Control Group
- Where
- 2 sites in United States
- Volunteers
- 59 people
- Sponsor
- Columbia University
Obstetric Pain
Ropivacaine Continuous Wound Infusion Versus Intrathecal Morphine for Postoperative Analgesia After Cesarean Delivery
Cesarean delivery is one of the most common surgical procedures, performed at an increasingly high rate. It is associated with intense postoperative pain that may hamper the rehabilitation process and interfere with patient…
- Trial name
- NCT03502642
- Testing
- wound infusion (Dosi-Pain® Kit, LEVENTON SAU, Spain), Spinal Anesthesia, intrathecal morphine
- Where
- Lebanon
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Saint-Joseph University
Pain
Evaluation of Risk Minimization, Assessment and Outcomes in Patients With Chronic Pain Taking Avinza
The purpose of this study is to provide information in a broad, "real world" population of chronic pain patients assessing both pain control with AVINZA as well as the potential risk for misuse and abuse.
- Trial name
- ACCESS 2008 (NCT00640042)
- Testing
- morphine sulfate extended release capsules
- Where
- 384 sites in United States, Puerto Rico
- Volunteers
- 1,570 people
- Sponsor
- Pfizer
Low Back Pain
Comparative Effectiveness Study for Surgery vs. Non-Surgery in Patients With Low Back Pain
Purpose: Comparative effectiveness research (CER) between surgical and non-surgical treatment for patients with low back pain Hypothesis: There will be significant differences in surgical and non-surgical treatment effect in…
- Trial name
- CES_SNS_LBP (NCT02883569)
- Testing
- open or endoscopic discectomy, epidural block, exercise
- Where
- South Korea
- Volunteers
- 1,102 people
- Sponsor
- Seoul National University Hospital
Delirium
Dexmedetomidine Versus Morphine and Midazolam in Prevention and Treatment of Delirium After Adult Cardiac Surgery
This randomized double-blind parallel clinical study was conducted on 60 patients undergoing elective cardiac surgery under general anesthesia, at least 60 yr old, ASA I and II, 70-100 kg body weight and height 160-180 cm.
- Trial name
- NCT03078946
- Testing
- Dexmedetomidine Hydrochloride, Morphine and Midazolam
- Volunteers
- 60 people
- Sponsor
- Ain Shams University
Pain, Postoperative
Thoracic Paravertebral Blockade in Video Assisted Thoracoscopic Surgery (VATS)
Video-assisted thoracoscopic surgeries (VATS) include severe postoperative acute pain which is also a predictor of chronic pain.
- Trial name
- VATS (NCT02302586)
- Testing
- Thoracic paravertebral block (TPVB), Patient Controlled Analgesia (IV PCA)
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Istanbul University
Postoperative Pain, Anesthesia, Local
Additional Effect of Wound Infiltration After Cesarean Section With Optimal Standard Analgesia
The purpose of this study is to determine wether wound infiltration brings additional analgesia effect after cesarean section with optimal standard postoperative analgesia
- Conditions
- Postoperative Pain, Anesthesia, Local, Breast Feeding
- Trial name
- KTcesar (NCT01751256)
- Testing
- Continuous wound infiltration
- Where
- France
- Volunteers
- 68 people
- Sponsor
- Poissy-Saint Germain Hospital
Ketamine, Morphine
PCA Ketamine-Morphine VS PCA Morphine as Post-Operative Analgesia in Colorectal Surgery.
The goal of this clinical trial is to compare the effectiveness of PCA ketamine-morphine versus conventional PCA morphine in postoperative patients undergoing elective laparotomy colorectal surgery under general anaesthesia.
- Trial name
- NCT06010056
- Testing
- Ketamine-Morphine, Morphine
- Where
- Malaysia
- Volunteers
- 60 people
- Sponsor
- National University of Malaysia
Osteoarthritis, Post-traumatic; Arthrosis
Do Corticosteroid Injections During Total Knee Replacement Improve Early Clinical Results?
Prior to surgery, a pharmacist will randomly assign participating patients to one of two groups. One group will get an injection in the knee during surgery that contains medications to limit pain and an antibiotic.
- Trial name
- NCT00492973
- Testing
- methylprednisolone acetate, active comparator
- Where
- United States
- Volunteers
- 101 people
- Sponsor
- New Lexington Clinic
Pharmacological Action, Post Operative Pain
The Postoperative Lidocaine and Ketamine Effects on Morphine Requirement in Bariatric Surgery
The goal of this observational study is to evaluate the quality of postoperative analgesia in a group of obese patients schedule to bariatric surgery under TIVA Opiod-free after to receive lidocaine and ketamine perfusion.
- Conditions
- Pharmacological Action, Post Operative Pain, Opioid Use, Obesity, Morbid
- Trial name
- NCT05591105
- Testing
- Control Group
- Where
- Spain
- Volunteers
- 64 people
- Sponsor
- Tiva Group
Cervical Cancer, Uterine Endometrial Cancer
Implementation of a Rapid Recovery Program in Gynecologic Oncology Surgery: A Pilot Study
Over 600,000 hysterectomies are performed annually in the United States. Despite increasing use of less invasive approaches, the majority of hysterectomies are still performed via traditional laparotomy, which can be associated…
- Conditions
- Cervical Cancer, Uterine Endometrial Cancer, Ovarian Cancer
- Trial name
- NCT01705288
- Testing
- Laparotomy, intravenous narcotics, standard anesthesia
- Where
- United States
- Volunteers
- 103 people, healthy volunteers welcome
- Sponsor
- Masonic Cancer Center, University of Minnesota
Low Back Pain
Analgesic Efficacy and Management of Opioid-induced Constipation (OIC) for Uncontrolled Moderate - Severe Low Back Pain
The primary objective is to assess the efficacy of oxycodone/naloxone (OXN) for the management of opioid-induced constipation (OIC) compared to oxycodone controlled-release tablets (OXY) in subjects with moderate to severe low…
- Trial name
- NCT01427270
- Testing
- Oxycodone/Naloxone controlled-release, Oxycodone HCl controlled-release
- Where
- 194 sites in United States, Czechia and 2 more
- Volunteers
- 455 people
- Sponsor
- Purdue Pharma LP
Healthy Volunteers
Pharmacokinetic Profile of OROS Hydromorphone in Healthy Taiwanese Participants With Different Genotypes for the UGT2B7 Gene
The purpose of this study is to investigate the pharmacokinetics of OROS hydromorphone in healthy adult Taiwanese participants after the oral administration of a single 16 mg dose.
- Trial name
- NCT01487564
- Testing
- Hydromorphone 16 mg
- Where
- Taiwan
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Janssen Research & Development, LLC
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