Clinical trials: Physical Therapy
Multiple Myeloma, Myeloma
Geriatric-assessment Interventions to Address Functional Deficits in Older Adults w Multiple Myeloma
Myeloma is the second most common type of blood cancer in the United States. Myeloma most commonly affects older adults. While some younger individuals do get myeloma, the average age when people are first diagnosed with myeloma…
- Conditions
- Multiple Myeloma, Myeloma, Disability Physical, Disabilities Multiple
- Trial name
- NCT04999085
- Testing
- Supportive care interventions
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- UNC Lineberger Comprehensive Cancer Center
Localized Prostate Carcinoma, Prostate Adenocarcinoma
Diet and Physical Activity Intervention for the Prevention of ADT-Induced Metabolic Changes in Patients With Prostate Cancer, TRIPLE-A PILOT Study
This clinical trial studies the effects of a diet and physical activity intervention on blood measures of lipids and insulin resistance in patients with prostate cancer undergoing radiation therapy (RT) and androgen deprivation…
- Trial name
- NCT04870515
- Testing
- Best Practice, Dietary Intervention, Exercise Intervention
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Fred Hutchinson Cancer Center
Asthma
Pilot of Lifestyle and Asthma Intervention
This is to pilot test a weight loss intervention in obese patients with poorly controlled asthma. Obesity is a risk factor for the development of asthma (approximately 250,000 cases per year of asthma in the U.S.
- Trial name
- PLAN (NCT03291808)
- Testing
- Weight loss intervention
- Where
- 2 sites in United States
- Volunteers
- 43 people
- Sponsor
- Johns Hopkins University
Primary Orthostatic Tremor
rTMS Therapy for Primary Orthostatic Tremor
Primary orthostatic tremor(POT) is a rare progressive functionally disabling tremor disorder. The characteristic features of POT are symptoms of unsteadiness in legs reported by patients when they are standing and improvement of…
- Trial name
- NCT02441985
- Testing
- Magstim RapidStim2, Fullerton Advanced Balance (FAB) Scale, Timed "Up & Go" Test (TUG) test
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- University of Florida
Gout
Validation Study of Physical Measurement of Tophi
The purpose of this study is to determine the inter- and intra-rater reproducibility of direct physical measurement of tophus nodules in subjects with gout.
- Trial name
- NCT00175006
- Testing
- Measurement of Tophi to validate procedure
- Volunteers
- 13 people
- Sponsor
- Takeda
Hypertension
Chiropractic for Hypertension in Patients
The investigators propose a prospective randomized 2 arm parallel observer-blinded phase II clinical study comparing a distinct method of upper cervical chiropractic manipulation to a sham technique in 50 individuals with stage I…
- Trial name
- CHiP (NCT01020435)
- Testing
- Spinal Manipulation
- Where
- United States
- Volunteers
- 51 people
- Sponsor
- Palmer College of Chiropractic
Non-specific Chronic Low Back Pain
Comparison of Electrotherapies for Chronic Low Back Pain
The intent of this project is to execute a high-quality double-blinded randomized controlled clinical trial that compares the H-Wave® device with a commonly used TENS device with a sub-therapeutic electrocurrent device.
- Trial name
- NCT01658735
- Testing
- H-Wave, Transcutaneous Electrical Nerve Stimulation (TENS)
- Volunteers
- 113 people
- Sponsor
- University of Utah
Bedwetting
Hand & Foot Nocturnal Enuresis TENS Study
The investigators believe in order to strengthen the evidence in support of transcutaneous foot stimulation in this population the investigators need to move forward with a randomized comparison study using the TENS device on the…
- Trial name
- NCT02747849
- Testing
- TENS
- Where
- United States
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Rajeev Chaudhry
Obesity
Engaging Men From Blue-collar Industries in Weight Loss
Objectives*: Primary Objective: Aim 1: Examine the acceptability of tailored behavioral weight loss program and a standard program in men working in blue-collar occupations.
- Trial name
- NCT05386238
- Testing
- Standard behavioral weight loss program, Tailored behavioral weight loss program
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Rush University Medical Center
Asthma
Comparison of Nebulizers in ED in Pediatric Asthma Patients
The primary objective will be, in an open-label randomized trial, a comparison of emergency department (ED) length of stay (LOS) between children experiencing acute asthma treated with two different nebulizers.
- Trial name
- NCT01951378
- Testing
- Hudson RCI® nebulizer, NebuTech® HDN® nebulizer, Albuterol
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Seton Healthcare Family
Obesity
ENDObesity® II Study: TransPyloric Shuttle® System for Weight Loss
The purpose of this clinical research trial is to study safety and effectiveness of the TransPyloric Shuttle System (TPSS) for weight reduction in patients who are considered medically obese.
- Trial name
- NCT02518685
- Testing
- TransPyloric Shuttle, Lifestyle Counseling
- Where
- 9 sites in United States
- Volunteers
- 302 people
- Sponsor
- BaroNova, Inc.
Metastatic Colorectal Carcinoma, Metastatic Malignant Neoplasm in the Liver
Liver Surgery and Chemotherapy in Treating Patients With Colorectal Cancer With Liver Metastases That Can Be Removed by Surgery and Lung Metastases That Cannot Be Removed by Surgery
This randomized phase II trial studies how well liver surgery and chemotherapy compared to chemotherapy alone work in treating patients with colorectal cancer that has spread to the liver (liver metastases) that can be removed by…
- Conditions
- Metastatic Colorectal Carcinoma, Metastatic Malignant Neoplasm in the Liver, Metastatic Malignant Neoplasm in the Lung, Recurrent Colorectal Carcinoma
- Trial name
- NCT02738606
- Testing
- Chemotherapy, Laboratory Biomarker Analysis, Metastasectomy
- Where
- United States
- Volunteers
- 29 people
- Sponsor
- M.D. Anderson Cancer Center
Diabetic Foot Ulcer
Phase 2a Multi-Center Prospective, Randomized Trial to Evaluate the Safety & Efficacy of Topical PEP-TISSEEL for Diabetic Foot Ulcers (DFU)
This is a Phase 2a Multi-Center, Prospective, Randomized, Controlled Study aimed to evaluate the Safety and Efficacy of Topically Applied PEP-TISSEEL in Subjects with Diabetic Foot Ulcers (DFU)
- Trial name
- NCT06319287
- Testing
- PEP (Purified Exosome Product) / TISSEEL
- Where
- United States
- Volunteers
- 59 people
- Sponsor
- Rion Inc.
Rheumatoid Arthritis
A Study of MabThera (Rituximab) in Patients With Rheumatoid Arthritis Who Have Failed on One Prior Anti-TNF Therapy (RESET)
This study will evaluate the safety and effectiveness of MabThera (rituximab) in patients with active rheumatoid arthritis who are receiving methotrexate, and who have a previous or current inadequate response to one prior…
- Trial name
- NCT01272908
- Testing
- rituximab
- Where
- 41 sites in Canada, Sweden
- Volunteers
- 120 people
- Sponsor
- Hoffmann-La Roche
Traumatic Brain Injury
Brain Injury Rehabilitation Improving the Transition Experience
Each year, about 2.8 million people sustain a traumatic brain injury (TBI) in the United States, and at least 25 percent of these injuries are classified as moderate to severe.
- Trial name
- BRITE (NCT03422276)
- Testing
- Rehabilitation Discharge Plan, Rehabilitation Transition Plan
- Where
- 6 sites in United States
- Volunteers
- 1,555 people
- Sponsor
- University of Washington
Trichiasis
Identification of TT Cases by Community Treatment Assistants: An Assessment
To achieve the goal of trachoma control as mandated by the World Health Organization, countries must reduce the backlog of trichiasis surgery cases to less than 1/1,000 of their population.
- Trial name
- SIMBA (NCT01783743)
- Testing
- TT Training Program and TT Screening Card
- Where
- United States
- Volunteers
- 27,473 people
- Sponsor
- Johns Hopkins University
Urticaria
Study to Investigate Safety, Tolerability, Pharmacodynamics and Pharmacokinetics of GSK2646264
This First Time in Human (FTIH) study, which will be performed in three parts, is designed to investigate the safety, local tolerability, pharmacokinetics and pharmacodynamics after single and repeat topical applications of up to…
- Trial name
- NCT02424799
- Testing
- GSK2646264 0.5% topical cream, GSK2646264 1% topical cream
- Where
- 6 sites in Germany, United Kingdom
- Volunteers
- 34 people
- Sponsor
- GlaxoSmithKline
Clinical Stage 0 Esophageal Adenocarcinoma AJCC v8, Clinical Stage 0 Esophageal Squamous Cell Carcinoma AJCC v8
Characterizing Chemo-Radiotherapy Treatment-Related Cardiac Changes
This trial studies cardiac changes after radiation or chemo-radiation for the treatment of lung or esophageal cancer that has not spread to other places in the body (non-metastatic) or has not come back (non-recurrent).
- Conditions
- Clinical Stage 0 Esophageal Adenocarcinoma AJCC v8, Clinical Stage 0 Esophageal Squamous Cell Carcinoma AJCC v8, Clinical Stage I Esophageal Adenocarcinoma AJCC v8, Clinical Stage I Esophageal Squamous Cell Carcinoma AJCC v8
- Trial name
- NCT04183218
- Testing
- Biospecimen Collection, Cardiac Event Monitor, Chemoradiotherapy
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Mayo Clinic
Iron Deficiency Anaemia, Chronic Kidney Disease
Ferric Carboxymaltose (FCM) Assessment in Subjects With Iron Deficiency Anaemia and Non-dialysis-dependent Chronic Kidney Disease (NDD-CKD)
Phase IIIb study to evaluate the long-term efficacy of ferric carboxymaltose (FCM) (using targeted ferritin levels to determine dosing) or oral iron in non-dialysis-dependent chronic kidney disease (NDD-CKD) subjects with iron…
- Trial name
- FIND-CKD (NCT00994318)
- Testing
- FCM (Ferric carboxymaltose) high ferritin target, FCM (Ferric carboxymaltose) low ferritin target, Oral Iron (Ferrous sulphate)
- Where
- 19 sites in United States, Australia and 17 more
- Volunteers
- 626 people
- Sponsor
- Vifor Pharma
Stroke
Community Participation Transition After Stroke
Stroke is one of the most serious, disabling health conditions in the United States. Patients who undergo rehabilitation treatment for stroke have a high rate of disability.
- Trial name
- COMPASS (NCT02396589)
- Testing
- Education Group, Home Modifications Group
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Washington University School of Medicine
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