Clinical trials: Physical activity
Choroidal Neovascularization (CNV)
Assess the Efficacy/Safety of Intravitreal Ranibizumab in Patients With Vision Loss Due to Choroidal Neovascularization.
This study was conducted to evaluate the efficacy and safety of 0.5 mg ranibizumab in adult and adolescent patients with visual impairment due to choridal neovascularization (CNV).
- Trial name
- NCT01840410
- Testing
- Ranibizumab
- Where
- 59 sites in Australia, Canada and 19 more
- Volunteers
- 183 people
- Sponsor
- Novartis Pharmaceuticals
Lung Cancer, Nonsmall Cell, Quality of Life
Use of the ADL-Glittre Test in the Pre and Postoperative Period of Patients With Lung Cancer
Lung cancer is the most common type of cancer and the leading cause of cancer death worldwide, in both men and women. Improvements in earlier preoperative staging and more effective adjuvant treatment have improved survival in…
- Conditions
- Lung Cancer, Nonsmall Cell, Quality of Life, Physical Disability, Surgery
- Trial name
- NCT05863013
- Testing
- ADL-Glittre Test
- Where
- Brazil
- Volunteers
- 80 people
- Sponsor
- Centro Universitário Augusto Motta
Neoplasm Malignant
First-in-human Single Agent Study of SAR442257 in RRMM and RR-NHL
Primary Objective: To determine the maximum tolerated dose (MTD) of SAR442257 administered as a single agent in patients with relapsed and refractory multiple myeloma (RRMM) and relapsed and refractory non-Hodgkin lymphoma…
- Trial name
- NCT04401020
- Testing
- SAR442257
- Where
- 16 sites in United States, Czechia and 3 more
- Volunteers
- 47 people
- Sponsor
- Sanofi
Diabetes Mellitus, Type 2, Metabolic Associated Fatty Liver Disease
Correlation Between Serum Nociceptin and Sympathetic Nerve Activity in Diabetic Patients With MAFLD
This observational study aims to investigate the relationship between serum nociceptin levels and sympathetic nervous system activity in patients with both type 2 diabetes mellitus (T2DM) and metabolic associated fatty liver…
- Trial name
- NCT07663682
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Second Hospital of Shanxi Medical University
Overweight or Obese Breast Cancer Patients
Motivating to Exercise and Diet, and Educating to Healthy Behaviors After Breast Cancer
The primary objective of MEDEA is to compare the effect of a personalised telephone-based health education weight loss program based on motivational coaching, exercise and diet versus a standard health educational program control…
- Trial name
- MEDEA (NCT04304924)
- Testing
- The personalized telephone based intervention
- Where
- France
- Volunteers
- 220 people
- Sponsor
- Gustave Roussy, Cancer Campus, Grand Paris
Dementia, Aging
Optimal Dog Visits
The aim of this project is to study how an the intensity of dog contact during dog visits in nursing homes can affect the immediate response to, and the general effect of the visits, and whether the residents' level of cognitive…
- Trial name
- NCT04635124
- Testing
- Dog visit, Encourage to engage in activity
- Volunteers
- 186 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Postmenopause
Use of the Synthetic Hormone CDB-2914 in Treating Symptoms of Menopause
This study will examine the safety and effectiveness of a synthetic hormone, CDB-2914, for treating symptoms of menopause. It will compare the effects of estrogen and CDB-2914 with those of estrogen and progesterone in…
- Trial name
- NCT00009659
- Testing
- CDB 2914
- Where
- United States
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Stroke
Disconnection and Unilateral Spatial Neglect
Retrospective cohort study of consecutive patients investigated in a neurorehabilitation ward after a first hemispheric stroke. Unilateral spatial Neglect (USN) and other cognitive impairments (including attention, executive…
- Trial name
- DISCONEGLECT (NCT05268159)
- Testing
- Cognitive assessment
- Where
- France
- Volunteers
- 300 people
- Sponsor
- University Hospital, Lille
Fibromyalgia, Autonomic Dysfunction
The Effects of Inspiratory Muscle Training Female Patients With Fibromyalgia
Fibromyalgia is a chronic condition characterized by widespread musculoskeletal pain, fatigue, sleep disturbances, and psychological symptoms.
- Trial name
- NCT07261696
- Testing
- Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 51 people
- Sponsor
- Nigde Omer Halisdemir University
Mild Haemophilia A Without Inhibitor
DDAVP vs. Exercise in Patients With Mild Hemophilia A
Individuals with mild hemophilia A (MHA) bleed infrequently but can in the setting of trauma which often is when participating in sports/exercise.
- Trial name
- NCT03136003
- Testing
- DDAVP, Exercise
- Where
- 2 sites in Canada
- Volunteers
- 30 people
- Sponsor
- The Hospital for Sick Children
Psychotic Disorders
A Comparison of Cognitive Training Approaches in Psychotic Disorders
Cognitive remediation (CR) is the best treatment to improve neurocognitive abilities for individuals with psychosis, however, there is no gold standard method of cognitive remediation available.
- Trial name
- NCT03024203
- Testing
- Cognitive Remediation - Executive Training, Cognitive Remediation - Perceptual Training
- Where
- Canada
- Volunteers
- 70 people
- Sponsor
- Queen's University
Spondylolisthesis, Spondylolysis
The Addition of a Pilates Program for Short-Term Improvements in Patients With Spondylolysis or Spondylolisthesis
Purpose: To determine the effectiveness of an augmented Pilates program, when combined to a multimodal strengthening program, for patients under the age of 21, who have spondylolysis and/or spondylolisthesis.
- Conditions
- Spondylolisthesis, Spondylolysis, Children
- Trial name
- NCT01711203
- Testing
- Motor Control, General Strengthening
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Megan Donaldson PT, PhD, FAAOMPT
Parkinson Disease
Changes in Functional Performance in Individuals With Parkinson's Disease Following 2-month Physiotherapy Intervention
Aim of current study was to evaluate the effect of a 2-month comprehensive physiotherapy intervention on different aspects of functional performance.
- Trial name
- NCT03568903
- Testing
- Comprehensive physical therapy
- Volunteers
- 44 people
- Sponsor
- University of Tartu
Healthy Volunteers
Interval Versus Continuous Training in Healthy Adults
Aerobic exercise produces increases in cardiorespiratory fitness (CF), which constitute a protective factor for cardiovascular disease and all-cause mortality.
- Trial name
- NCT02288403
- Testing
- Aerobic interval training, Continuous training
- Where
- Colombia
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Universidad de Antioquia
Breast Cancer Female
Breaking Through the Brain Fog: An Online Research Study
This study will investigate the benefits of distinct brain health trainings in breast cancer survivors (age 30-80) with cognitive concerns post-chemotherapy. This study can be completed from the comfort of participant's own home.
- Trial name
- NCT05444231
- Testing
- Brain Training A, Brain Training B, Brain Training C
- Where
- United States
- Volunteers
- 193 people
- Sponsor
- The University of Texas at Dallas
Muscle Activation, Electromyography
Analysis of Shoulder Muscle Activity During Isokinetic Evaluation of Rotators
The objective of this study is to assess the impact of different positions of the glenohumeral joint on the maximum muscle contraction of different shoulder muscles.
- Conditions
- Muscle Activation, Electromyography, Muscle Strength, Shoulder
- Trial name
- NCT04312529
- Testing
- Isokinetic test + EMG
- Where
- Belgium
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Liege
Mental Health Wellness 1, Depression, Anxiety
Mental Health in Fitness Instructors
The aim of this project is to improve the evidence-base regarding lifestyle and mental health symptoms among fitness instructors.
- Conditions
- Mental Health Wellness 1, Depression, Anxiety, Eating Disorders, Eating Behavior
- Trial name
- NCT04135729
- Where
- Norway
- Volunteers
- 304 people
- Sponsor
- Norwegian School of Sport Sciences
PreDiabetes
Study: Diet and Exercise Study to Improve Brain Blood Flow: Blood Flow Improvement Trial
Project Summary Metabolic syndrome (MetS) is associated with the development of diabetes and cardiovascular disease; however it is also linked with cognitive decline and dementia.
- Trial name
- BFIT (NCT03117829)
- Testing
- Diet and Exercise
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Intracranial Neoplasm, Low Grade Glioma
Fluoroethyltyrosine for Evaluation of Intracranial Neoplasms
This phase II trial studies how well F-18 fluoroethyltyrosine (fluoroethyltyrosine) works in detecting tumors in participants with intracranial tumors that have come back.
- Conditions
- Intracranial Neoplasm, Low Grade Glioma, Recurrent Glioblastoma, Recurrent World Health Organization (WHO) Grade II Glioma
- Trial name
- UC-GlioFET (NCT04044937)
- Testing
- F-18 Fluoroethyltyrosine (FET), Positron Emission Tomography (PET)
- Where
- United States
- Volunteers
- 143 people
- Sponsor
- Thomas Hope
Exercise Training
Plyometric Exercise to Improve Rapid Force Production in Older Men
Rapid force production declines as a consequence of ageing. Given the functional relevance of rapid force production, exercise interventions in older adults should aim at improving the capacity to produce force rapidly.
- Trial name
- NCT03645772
- Testing
- Exercise intervention
- Where
- Belgium
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- KU Leuven
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