Clinical trials: Radiation, completed
Oral Mucositis
Study to Determine the Effects Treatment With Amlexanox 0.5% Oral Rinse Solution on Oral Mucositis Associated With Radiation Therapy for Cancer of the Head and Neck Region
The purpose of this study was to determine the effect of 0.5% amlexanox oral rinse compared to a vehicle control on mucositis-related ulceration and erythema (objective score)and on mucositis-related oral pain (subjective score).
- Trial name
- NCT01083875
- Testing
- amlexanox, Vehicle rinse
- Where
- 12 sites in United States
- Volunteers
- 58 people
- Sponsor
- Access Pharmaceuticals, Inc.
Bone Fracture
Vibration as a Method of Fracture Screening in Children
When assessing an injured child, doctors must decide whether or not there is an underlying bone fracture. The best way of doing this is to take an x-ray.
- Trial name
- NCT04643912
- Testing
- Vibration Device
- Where
- United Kingdom
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Sheffield Children's NHS Foundation Trust
Ultrasonography, Interventional, Peripheral Venous Catheterization
Comparing Ultrasound Guided PICC Line Insertion in Neonates With Standard Procedure
This is a randomized controlled study comparing US guided vs standard procedure for PICC line placement in newborns admitted to Children's Hospital of Eastern Ontario Neonatal Intensive Care Unit who require a PICC line.
- Trial name
- NCT02584530
- Testing
- Ultrasound guidance for PICC line placement
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- Children's Hospital of Eastern Ontario
Brain Cancer, Neoplasm Metastasis
Phase I Vorinostat Concurrent With Stereotactic Radiosurgery (SRS) in Brain Metastases From Non-Small Cell Lung Cancer
The purpose of this study is to determine the maximum tolerated dose (MTD) of vorinostat given concurrently with stereotactic radiosurgery (SRS) to treat non-small cell lung cancer (NSCLCA) brain metastases in patient with 1-4…
- Conditions
- Brain Cancer, Neoplasm Metastasis, Lung Cancer, Carcinoma, Non-Small-Cell Lung
- Trial name
- NCT00946673
- Testing
- Vorinostat, Radiation Therapy
- Where
- 2 sites in United States
- Volunteers
- 17 people
- Sponsor
- Stanford University
Gingival Recession
Effect of Low-Level Laser on Pain and Healing of Donor Site Following Free Gingival Graft
The aim of this randomized split-mouth design clinical trial is to clinically evaluate the effectiveness of diode laser in the healing of donor site of palate in free gingival graft.
- Trial name
- NCT02896283
- Testing
- Low-level laser therapy, Turned-off laser
- Where
- Iran
- Volunteers
- 12 people
- Sponsor
- Tehran University of Medical Sciences
Colorectal Cancer, Surveillance
Intensive Versus Minimal Surveillance of Patients With Resected Dukes B2-C Colorectal Carcinoma
Dukes B2-C colorectal cancer patients who had no evidence of disease at the end of their front line treatment (surgery and adjuvant radio-chemotherapy, if indicated) are eligible for the trial and randomized to two different…
- Trial name
- GILDA (NCT02409472)
- Testing
- surveillance program after completion of primary treatment
- Volunteers
- 1,242 people
- Sponsor
- Mario Negri Institute for Pharmacological Research
Regional Body Composition, Cortisol and Testosterone Levels
Effect of Football on the Musculoskeletal System and Hormonal System
Several studies have shown that football practice regulates bone remodeling, producing an increase of bone mineral density and reducing the risk of fractures.
- Trial name
- NCT04839172
- Testing
- Dual-energy X-ray Absorptiometry (DXA) scan
- Where
- Spain
- Volunteers
- 30 people
- Sponsor
- Cardenal Herrera University
Soft Tissue Sarcoma
Neoadjuvant and Adjuvant Chemotherapy in High-risk Soft Tissue Sarcoma
Neo- and adjuvant chemotherapy is used in high-risk soft tissue sarcoma to improve systemic control. Patients in this trial are treated with 4 cycles of chemotherapy (EIA, etoposide, ifosfamide, adriamycin) preoperatively…
- Trial name
- NeoWTS (NCT01382030)
- Testing
- EIA chemotherapy
- Where
- Germany
- Volunteers
- 50 people
- Sponsor
- Heidelberg University
Stage I Prostate Adenocarcinoma American Joint Committee on Cancer (AJCC) v7, Stage II Prostate Adenocarcinoma AJCC v7
Stereotactic Body Radiation Therapy in Treating Patients With High-Risk Prostate Cancer Undergoing Surgery
This phase I trial studies stereotactic body radiation therapy (SBRT) in treating patients with prostate cancer that is likely to come back or spread (high-risk) undergoing surgery.
- Conditions
- Stage I Prostate Adenocarcinoma American Joint Committee on Cancer (AJCC) v7, Stage II Prostate Adenocarcinoma AJCC v7, Stage III Prostate Adenocarcinoma AJCC v7
- Trial name
- NCT02830165
- Testing
- Laboratory Biomarker Analysis, Quality-of-Life Assessment, Stereotactic Body Radiation Therapy
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- Jonsson Comprehensive Cancer Center
Prostate Adenocarcinoma, Stage IIB Prostate Cancer
Copper Cu 64 TP3805 PET in Detecting Cancer in Patients With Prostate Cancer Undergoing Surgery
This pilot phase I trial studies copper Cu 64 TP3805 (Cu-64-TP3805) positron emission tomography (PET)/computed tomography (CT) in detecting cancer in patients with prostate cancer undergoing surgery to remove the entire prostate…
- Conditions
- Prostate Adenocarcinoma, Stage IIB Prostate Cancer, Stage III Prostate Cancer, Stage IV Prostate Cancer
- Trial name
- NCT02603965
- Testing
- Copper Cu 64 TP3805, Positron Emission Tomography, Computed Tomography
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University
Malocclusion, Angle Class II
Effect of Low-Intensity Pulsed Ultrasound on Functional Treatment of Class II Malocclusion
This experimental study will evaluate the effect of combined treatment with low-intensity pulsed ultrasound (LIPUS) and functional appliances (twin-block) on the correction of class II malocclusion, compared with the control…
- Trial name
- NCT03251807
- Testing
- Twin-block, LIPUS (Low-intensity pulsed ultrasound)
- Where
- Syria
- Volunteers
- 40 people
- Sponsor
- Damascus University
Uterine Cervical Neoplasms
Exclusion of Non-involved Uterus From the Target Volume in Locally Advanced Cervical Cancer
Both toxicity and local relapse are major concerns in the treatment of locally advanced cervical cancer. The purpose of this study is to ameliorate both by integrating modern imaging (diffusion weighted magnetic resonance…
- Trial name
- EXIT (NCT03542942)
- Testing
- treatment with EXIT-target volume
- Where
- Belgium
- Volunteers
- 21 people
- Sponsor
- University Hospital, Ghent
Carcinoma, Non-small-cell Lung
Prevention of Radiation Pneumonitis After Three-dimensional Conformal Radiation Therapy (3D-CRT) in Patients With Non-small-cell Lung Cancer
The purpose of this study is to evaluate the interest of breath holding for the prevention of radiation pneumonitis following conformal radiation therapy.
- Trial name
- NCT00349102
- Testing
- Free breathing, Breath holding
- Where
- 7 sites in France
- Volunteers
- 242 people
- Sponsor
- Centre Leon Berard
Chronic Pain
Exploratory Evaluation of [11C]-NOP46
This is an open-label, single center design. In the first stage, five (5) healthy individuals will receive a microdose (10µg) of [11C]-NOP46, immediately followed by whole body positron emission tomography (PET)/computed…
- Trial name
- NCT03705819
- Testing
- [11C]-NOP46, PET/CT scan
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Columbia University
Cancer
Imaging NSCLC Treatment Response to Immunotherapy
This feasibility study will aim to assess the potential for functional imaging biomarkers (18FDG PET-CT and DW-MRI) to differentiate immunotherapy induced inflammation, indicative of response from non-response in patients with…
- Trial name
- NCT02753569
- Testing
- Imaging - DW-MRI, FDG PET-CT
- Where
- United Kingdom
- Volunteers
- 10 people
- Sponsor
- Institute of Cancer Research, United Kingdom
Necrotizing Enterocolitis
NEC Thermography Infrared Imaging Study
Necrotizing enterocolitis (NEC) is a devastating disease affecting the intestines of premature infants. It involves intestine swelling, tissue destruction, infection, and even death.
- Trial name
- NCT03994341
- Testing
- A FLIR Thermovision a320M thermal IR camera
- Where
- 2 sites in Canada
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Ottawa Hospital Research Institute
Pancreatic Cancer
Gemcitabine and Radiation Therapy in Treating Patients With Cancer of the Pancreas
RATIONALE: Radiation therapy uses high-energy x-rays to damage tumor cells. Gemcitabine may make tumor cells more sensitive to radiation therapy.
- Trial name
- NCT00010166
- Testing
- gemcitabine hydrochloride, adjuvant therapy, radiation therapy
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- Wake Forest University Health Sciences
Neuroblastoma
Therapy Based on Stage of Disease and Risk Assessment in Treating Children With Neuroblastoma
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining chemotherapy with bone marrow transplantation may allow the doctor to give higher doses of…
- Trial name
- NCT00002802
- Testing
- carboplatin, cisplatin, cyclophosphamide
- Where
- Germany
- Volunteers
- 500 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Liver Cancer
Stereotactic Radiation Therapy in Treating Patients With Advanced Liver Cancer
This is a phase I trial studying the side effects and best dose of stereotactic radiation therapy (SRT) in treating patients with advanced liver cancer.
- Trial name
- NCT00607828
- Testing
- stereotactic body radiation therapy
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- University of Nebraska
Glioblastoma
Study With Nelfinavir and Combined Radiochemotherapy for Glioblastoma
The objectives of the trial are: To assess safety, tolerability and activity of nelfinavir given neo-adjuvant and concomitant to chemoradiotherapy with temozolomide in patients with a newly diagnosed glioblastoma multiforme.
- Trial name
- NCT00694837
- Testing
- nelfinavir
- Where
- Netherlands
- Volunteers
- 6 people
- Sponsor
- Maastricht Radiation Oncology
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