Clinical trials: Ropivacaine
Hysterectomy
SUperior Hypogastric Plexus Block During Laparoscopic hysterEctomy (SUBTLE)
This trial sest to assess the efficacy of a superior hypogastric plexus block (SHPB) for quality of recovery after a laparoscopic hysterectomy.
- Trial name
- SUBTLE (NCT06455540)
- Testing
- Superior hypogastric plexus block
- Volunteers
- 198 people
- Sponsor
- Sixth Affiliated Hospital, Sun Yat-sen University
Femoral Neck Fracture
Ropivacaine Hypobaric Spinal Anaesthesia in Traumatic Hip Surgery
This is a prospective, monocentric, randomized study, comparing the effectiveness and tolerance of four different dosages of hypobaric ropivacaine for unilateral spinal anaesthesia during traumatic femoral neck surgery in the…
- Trial name
- NCT01005550
- Testing
- 6 mg of ropivacaine, 8 mg of ropivacaine, 10 mg of ropivacaine
- Where
- France
- Volunteers
- 64 people
- Sponsor
- Hospices Civils de Lyon
Pain, Postoperative
Pain Management Study
This study aims to better understand the role that narcotic vs. non-narcotic multimodal pain management play in patients' pain following bariatric surgery (Laproscopic Surgery and Robotic Assisted Surgery).
- Trial name
- NCT05231460
- Testing
- Active Comparator: narcotic regimen with TAP block, Active Comparator: narcotic regimen with no TAP block, non-narcotic regimen with TAP block
- Where
- United States
- Volunteers
- 244 people
- Sponsor
- University of Arizona
Pancreatic Cancer
Influence of Local Anesthetic Administration on the Cancer Recurrence Rate After Pancreatic Oncologic Surgery
Study aims to compare the influence of intravenous lidocaine and peridural ropivacaine on postoperative long and short term outcome in patients with pancreatic cancer undergoing surgery.
- Trial name
- NCT04449289
- Testing
- Intravenous lidocaine, Epidural ropivacaine
- Where
- Romania
- Volunteers
- 100 people
- Sponsor
- Institutul Regional de Gastroenterologie & Hepatologie Prof. dr. Octavian Fodor
Cardiac Surgery
A Phase II/III Study of Continuous Local Anesthetic Infusion in Median Sternotomy Following Cardiac Surgery
Cardiac surgery is associated with pain in the post-operative period. We plan to conduct a study of local anesthetic, ropivacaine, infusion into the sternal wound in adult patients undergoing cardiac surgery to see if it will be…
- Trial name
- NCT00586976
- Testing
- Ropivacaine, Normal saline
- Where
- United States
- Volunteers
- 125 people
- Sponsor
- Mayo Clinic
Testicle Undescended, Pain, Postoperative
Evaluating Pain Outcomes of Caudal vs Ilioinguinal Nerve Block in Children Undergoing Orchiopexy Repair
Surgical intervention to treat undescended testis is a very common pediatric surgical procedure, often performed using an inguinal incision or subscrotal incision approach.
- Trial name
- NCT03041935
- Testing
- Ilioinguinal/iliohypogastric nerve block, Caudal-epidural nerve block, Acetaminophen
- Where
- Canada
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Alberta Children's Hospital
Popliteal Sciatic Nerve Block
Comparing Classical Approach and Crosswise Approach to Popliteal Sciatic Nerve Block
Sensory and motor innervation below the knee is provided mainly by the popliteal-sciatic nerve except for a variable area of the medial leg supplied by the saphenous nerve.
- Trial name
- NCT07134608
- Testing
- Popliteal Plexus Block with 20 ml
- Where
- Malaysia
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- National University of Malaysia
Labor Pain, Complications; Cesarean Section
Outcomes of Neuraxial Anesthetic Technique on the Trial of Labor After Cesarean (TOLAC)
To compare the effects of epidural versus combined spinal and epidural (CSE) anesthesia on the success of Trial of Labor After Cesarean (TOLAC).
- Conditions
- Labor Pain, Complications; Cesarean Section, Pregnancy
- Trial name
- NCT02105558
- Testing
- Epidural anesthesia, Combined spinal and epidural anesthesia
- Where
- United States
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center, Houston
Breast Cancer, Acute Pain
Mid-point Transverse Process to Pleura Block for Breast Cancer Surgery: A Randomized Controlled Trial
This study will compare the analgesic effects of midpoint transverse process to pleura (MTP) block to control as well as thoracic paravertebral block.
- Conditions
- Breast Cancer, Acute Pain, Anesthesia
- Trial name
- NCT03713255
- Testing
- PVB group, MTP block group, Control Group
- Where
- Canada
- Volunteers
- 150 people
- Sponsor
- Ottawa Hospital Research Institute
Hip Arthroplasty, Total, Post Operative Pain, Acute
Supra Inguinal Fascia Iliaca Block as Rescue Analgesia Following Total Hip Arthroplasty
Hip replacement surgery is one of the most commonly performed surgical procedures in France, with approximately 150,000 procedures per year.
- Conditions
- Hip Arthroplasty, Total, Post Operative Pain, Acute, Nerve Block
- Trial name
- SOSBIFSI (NCT06982625)
- Testing
- Ultrasound guided supra inguinal fascia iliaca block, Surgical and anesthetic protocol
- Where
- France
- Volunteers
- 310 people
- Sponsor
- Institut Mutualiste Montsouris
Pain, Postoperative
Local Anesthetic Continuous Preperitoneal Infiltration and Wound Hyperalgesia
In this multicenter, randomised, placebo-controlled, double-blind trial, hyperalgesia area around the scarce following colorectal laparoscopic surgery (piece removal) will be assessed in 3 groups of patients : group 1: continuous…
- Trial name
- CATCH (NCT01077752)
- Testing
- continuous ropivacaine preperitoneal infusion, intravenous lidocaine infusion, parenteral analgesia combining acetaminophen and morphine
- Where
- France
- Volunteers
- 95 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Postoperative Pain
Comparison of Administation Routes of Ropivacaine
The purpose of this study is to evaluate the effect of different routes of local anaesthesia administration in laparoscopic procedures to reduce post-operative pain (intra-peritoneal infusion of Ropivacaine 0.75%, port site…
- Trial name
- NCT04459026
- Testing
- combination, infiltration, instillation
- Where
- Belgium
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Universiteit Antwerpen
Osteoarthritis
Local Anesthetic Infiltration and Infusion for Pain Control After Hip Replacement
The purpose of this study is to examine three different ways to control pain after hip replacement: 1. One time injection of ropivacaine before wound closure 2.
- Trial name
- NCT01409278
- Testing
- Ropivacaine infiltration and saline infusion., Ropivacaine infiltration and infusion., Normal Saline
- Where
- United States
- Volunteers
- 105 people
- Sponsor
- Trinity Health Of New England
Local Anesthetic Systemic Toxicity, Anesthesia, Local
Ropivacaine Plasma Concentration With or Without Epinephrine for Posterior Quadratus Lumborum Block
Introduction The posterior Quadratus Lumborum Block (pQLB) has been used in postoperative pain management after Cesarean Section (CS).
- Trial name
- NCT04562103
- Testing
- Epinephrine / Ropivacaine, Ropivacaine
- Where
- Italy
- Volunteers
- 52 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Vasalgia, Headache
The Effect of Sphenopalatine Ganglion Block on Headache and Vasalgia
The purpose of this study is to evaluate the effect of sphenopalatine ganglion block (SPG block) on headache and veisalgia (hangover) the day after attending the metal festival Copenhell.
- Conditions
- Vasalgia, Headache, Hangover
- Trial name
- NCT07060586
- Testing
- Sphenopalatine Ganglion Block
- Where
- Denmark
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- University Hospital Bispebjerg and Frederiksberg
Postoperative Analgesia, S-ketamine
Analgesic Effects of Caudal S-ketamine for Supplementation of Ropivacaine Caudal Analgesia in Children With Hypospadias
Caudal analgesia with ropivacaine is commonly used in sub-umbilical pediatric surgery. However, increasing the dosage of ropivacaine has not been found to prolong the action significantly while complications will be serious.
- Conditions
- Postoperative Analgesia, S-ketamine, Pediatrics, Caudal Block
- Trial name
- NCT05922605
- Testing
- S-ketamine & Ropivacaine, Ropivacaine
- Where
- China
- Volunteers
- 44 people
- Sponsor
- Tao Zhang
Traumatic Rib Fracture(s)
Rib Fracture Analgesia Using Cryoanalgesia
Rib fractures are one of the most common injuries in trauma patients. These fractures are associated with significant pain as well as decreased ability to inspire deeply or cough to clear secretions, which together lead to…
- Trial name
- NCT04198662
- Testing
- Cryoneurolysis with a Painblocker (Epimed International, Farmers Branch, Texas), Intercostal nerve block ropivacaine with epinephrine
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of California, San Diego
Postoperative Pain
Erector Spinae Block With Ropivacaine and Dexmedetomidine on Opioid Consumption After Lumar Spine Surgeries
The aim of this study is to investigate the role of 0.5 micrograms/kg of dexmedetomidine with 0.2 % ropivacaine in erector spinae block in reducing opioid consumption for patients undergoing lumbar spine surgeries.
- Trial name
- NCT05664542
- Testing
- ESPB (regional Block), ropivacaine and dexmedetomidine
- Where
- Saudi Arabia
- Volunteers
- 42 people
- Sponsor
- Security Forces Hospital
PTSD, Cardiac Arrest
Stellate Ganglion Blockade to Reduce Cardiac Anxiety and PTSD Symptoms in Cardiac Arrest Survivors
This is a pilot randomized controlled trial (RCT) to gain preliminary evidence regarding the acceptability, tolerability, safety, and efficacy of a combined intervention of Stellate Ganglion Blockade (SGB) and psychoeducation on…
- Conditions
- PTSD, Cardiac Arrest, Anxiety and Fear, Sleep Disturbance
- Trial name
- SGB-PsychoED (NCT04582396)
- Testing
- stellate ganglion block injection, Normal saline injection, Psychoeducation
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Columbia University
Vulvodynia, Vestibulodynia
Effects of Flourish HEC on Localized Provoked Vulvodynia
This study is designed to determine whether improving the vaginal microbiome in women with localized provoked vulvodynia (LPV) may help improve pain better than routine care alone.
- Conditions
- Vulvodynia, Vestibulodynia, Vulvar Diseases, Vulvar Vestibulitis
- Trial name
- NCT05478746
- Testing
- BioNourish, a component of the Flourish HEC kit, Control - no intervention
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- Vaginal Biome Science
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