Clinical trials: Ropivacaine
Knee Osteoarthritis, Knee Pain Chronic
Dexamethasone for iPACK Block With ACB in Total Knee Arthroplasty
Effect of adding Dexamethasone to Infiltration between the Popliteal Artery and Capsule of the Knee Block with ACB in Patients undergoing Total Knee Arthroplasty
- Conditions
- Knee Osteoarthritis, Knee Pain Chronic, Knee Arthritis
- Trial name
- NCT06470204
- Testing
- Ropivacaine, Ropivacaine+Dexamethasone
- Where
- Poland
- Volunteers
- 60 people
- Sponsor
- Poznan University of Medical Sciences
Cesarean Section, Local Anesthetic
Chloroprocaine 1% Versus Ropivacaine 0,75% During Cesarean Section
This will be a prospective randomized study, aiming at comparing an intrathecal fixed dose of chloroprocaine 1% versus an intrathecal fixed dose of ropivacaine 0.75% in elective cesarean sections
- Trial name
- annie-mariana (NCT06376058)
- Testing
- Chloroprocaine 1% Injectable Solution, Ropivacaine 0.75% Injectable Solution
- Where
- Greece
- Volunteers
- 60 people
- Sponsor
- Aretaieion University Hospital
Efficacy and Safety of MgSO4 as Adjuvant to Scalp Block
The Efficacy and Safety of Magnesium Sulphate Adjuvant in Scalp Block With Ropivacaine for Supratentorial Craniotomy: a Prospective, Randomized Controlled Trial
A randomized, double-blinded controlled trial was conducted to evaluate the analgesic efficacy of MgSO4 as an adjuvant to ropivacaine in scalp blocks for craniotomy, focusing on its impact on hemodynamic parameters and…
- Trial name
- NCT07075783
- Testing
- MgSO4 plus Ropivacaine, Plain Ropivacaine
- Where
- Malaysia
- Volunteers
- 24 people
- Sponsor
- Hospital Universiti Sains Malaysia
Pain Management, Spine Surgery
Minimum Effective Dose of Incisional Local Infiltration Betamethasone for the Prevention of Pain After Spinal Surgery
Incisional pain is a common complication after surgery and is an important cause of delayed postoperative recovery, increased length of hospital stay, increased risk of wound infection and respiratory/cardiovascular…
- Trial name
- NCT06785350
- Testing
- 0.012%diprospan+0.5%ropivacaine, 0.009%diprospan+0.5%ropivacaine, 0.006%diprospan+0.5ropivacaine
- Where
- China
- Volunteers
- 535 people
- Sponsor
- Beijing Tiantan Hospital
Hip Osteoarthritis, Hip Pain Chronic
Dexamethasone With Ropivacaine for PENG Block in Total Hip Arthroplasty
Does adding Dexamethasone to the Periarticular Nerve Group Block in Patients undergoing Total Hip Arthroplasty reduce the dose of ropivacaine?
- Conditions
- Hip Osteoarthritis, Hip Pain Chronic, Hip Arthritis
- Trial name
- NCT06470334
- Testing
- Ropivacaine, Ropivacaine+Dexamethasone
- Where
- Poland
- Volunteers
- 60 people
- Sponsor
- Poznan University of Medical Sciences
Hip Disease, Hip Dysplasia
PENG With LFCB vs. ESP Blocks for Pediatric Hip Surgery
This randomized controlled trial (RCT) compares the analgesic effectiveness of two regional anesthesia techniques-Pericapsular Nerve Group (PENG) block combined with Lateral Femoral Cutaneous Nerve Block (LFCB) versus Lumbar and…
- Conditions
- Hip Disease, Hip Dysplasia, Hip Arthropathy
- Trial name
- NCT07023094
- Testing
- Ropivacaine 0.2% for PENG Block, Ropivacaine 0.2% for LFCB, Ropivacaine 0.2% for L-ESPB
- Where
- Poland
- Volunteers
- 60 people
- Sponsor
- Poznan University of Medical Sciences
Distal Radius Fractures, Lidocaine
Ultrasound-guided Infraclavicular Block With Lidocaine or Ropivacaine for Closed Reduction of Distal Radius Fractures
To investigate the feasibility of the lateral infraclavicular plexus brachialis (LIC) block for acute closed reduction of distal radius fractures, the investigators will compare the pain-relieving and muscle-relaxing properties…
- Conditions
- Distal Radius Fractures, Lidocaine, Ropivacaine, Fracture Dislocation
- Trial name
- NCT06379490
- Testing
- Ropivacaine 0.2% Injectable Solution, Lidocaine epinephrine, Ropivacaine 0.5% Injectable Solution
- Where
- Denmark
- Volunteers
- 67 people
- Sponsor
- Nordsjaellands Hospital
Hypotension, Pain
The Prevention of Hypotension After Epidural Analgesia After Major Surgery
Epidural analgesia via continuous epidurally infused local anesthetic agent (LA) is widely and very successfully used routinely for perioperative pain control in patients undergoing major orthopedic and abdominal surgery since…
- Trial name
- NCT02722746
- Testing
- Ropivacaine, Epinephrine
- Where
- United States
- Volunteers
- 66 people
- Sponsor
- University of Florida
Breast Cancer Female
PEMF and PEC Blocks in Mastectomy Reconstruction Patients
This is a prospective randomized controlled double-blind interventional study comparing the effect of pulsed-electromagnetic field device (PEMF), pectoral interfascial block (PIB), and placebo on postoperative pain control.
- Trial name
- NCT03360214
- Testing
- Bupivacaine Hydrochloride, Pulsed Electromagnetic Field (PEMF) Device, Ropivacaine Hydrochloride
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Columbia University
Thoracic Surgery
Local Anesthetic as Single Shot Versus Catheter in Patients Undergoing Video Assisted Thoracoscopic Surgery
The purpose of this research is to compare a single shot long acting local anesthetic to catheter infusion of local anesthetic in patients undergoing video assisted thoracoscopic (VAT) surgery.
- Trial name
- NCT04559347
- Testing
- Liposomal Bupivacaine (EXPAREL®)/Bupivacaine, Ropivacaine (0.5% bolus followed by 0.2% infusion)
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- Poovendran Saththasivam
Adenotonsillectomy
Dexmedetomidine as Adjuvant for Suprazygomatic Maxillary Nerve Block in Children's Adenotonsillectomy
The goal of this clinic trial is to evaluate the impact of dexmedetomidine as an adjunct pain pain medication on opioid-free recovery in children undergoing adenotonsillectomy with Suprazygomatic maxillary nerve block (SZMB).
- Trial name
- SZMB (NCT07013526)
- Testing
- Ropivacaine
- Where
- Canada
- Volunteers
- 150 people
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Labor Analgesia, Prolonged
Effects of Ropivacaine Concentrations on Prolonged Labor Analgesia
With the changes in medical models and improvements in people's quality of life, parturients have higher demands for childbirth, making the alleviation and elimination of labor pain an important aspect of modern obstetrics.
- Conditions
- Labor Analgesia, Prolonged, Ropivacaine, Concentration
- Trial name
- NCT07007650
- Testing
- High-concentration Ropivacaine, Low concentration ropivacaine group
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Chengdu Jinjiang Maternity and Child Health Hospital
Patella Fracture
Effects Of Intra-Operative Intra-Articular Cocktail Injection In Patella Open Reduction And Internal Fixation
The objective of this study is to demonstrate the safety and efficacy of an intra-articular analgesics cocktail injection for post-operative patella fracture fixation patients, by comparing post-operative pain relief and…
- Trial name
- NCT07006168
- Testing
- Ketorolac 15mg, Triamcinolone Acetonide 40mg, Ropivacaine HCL 1% 15ml
- Where
- Hong Kong
- Volunteers
- 56 people
- Sponsor
- The University of Hong Kong
Pain, Pain Management Following Cardiopulmonary Bypass Surgery
Addition of Dexmedetomidine to Ropivacaine in Bilateral Erector Spinae Plane Block in Patients Undergoing Coronary Artery Bypass Surgery
Coronary artery bypass surgery (CABG), typically performed through a median sternotomy, causes significant postoperative pain. Managing this pain effectively while reducing reliance on opioids is essential, as opioids can lead to…
- Conditions
- Pain, Pain Management Following Cardiopulmonary Bypass Surgery, Erector Spinae Plane Block
- Trial name
- NCT06981949
- Testing
- Dexmedetomidine, Ropivacaine
- Volunteers
- 110 people
- Sponsor
- Lebanese American University
Healthy, Nerve Block
Phase I Study of Ropivacaine, Clonidine, and Betamethasone Combination for Sciatic Nerve Block in the Popliteal Region
This is a national, single-center, dose-escalation Phase I study to investigate the safety, pharmacokinetics, and efficacy of a combination containing Ropivacaine, Clonidine, and Betamethasone (Ropiclobet) in healty volunteers.
- Trial name
- RopiCloBet (NCT06781632)
- Testing
- ropivacaine
- Where
- Turkey (Türkiye)
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- PHARMAFINA
Amputation
Combined Local Anesthetic Blockade and Neuromodulation vs Local Anesthetic Blockade Only for Analgesia After Below-knee Amputation: RCT
This multi-site clinical trial aims to assess the efficacy and safety of combining peripheral nerve stimulation with local anesthetic nerve blockade compared to the standard of care, i.e., local anesthetic blockade only using…
- Trial name
- NCT06964347
- Testing
- Ropivacaine 0.2% + nerve stimulator set, Ropivacaine 0.2%
- Where
- 4 sites in United States, Canada
- Volunteers
- 62 people
- Sponsor
- Stanford University
Distribution of Ropivacaine in Erector Spinae Plane Block
Distribution, Pharmacokinetics and Extent of Sensory Blockade in ESP Blocks
The primary objectives of this study are to define the extent of dermatomal anesthesia and anatomical spread of injectate (as defined by MRI imaging) that is provided by an ESP block at the T5 level, using twenty milliliters of…
- Trial name
- NCT03476642
- Testing
- Ropivacaine, Epinephrine
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Milton S. Hershey Medical Center
Total Knee Arthroplasty
Periarticular Bupivacaine + Meloxicam ER Solution Versus Standard Practice During Total Knee Arthroplasty
The purpose of this study is to compare an FDA-approved medication for post-operative pain control (HTX-011) to the standard of care institutional practice for periarticular analgesia after primary total knee arthroplasty (weight…
- Trial name
- NCT05188053
- Testing
- HTX-011, ropivacaine , epinephrine , ketorolac diluted in sodium chloride
- Where
- United States
- Volunteers
- 209 people
- Sponsor
- Mayo Clinic
Pregnancy Related
Effectiveness of Clonidine, Dexmedetomidine, and Fentanyl Adjuncts for Labor Epidural Analgesia
The purpose of this randomized controlled trial is to compare the effectiveness of epidural clonidine, dexmedetomidine, or fentanyl adjuncts for labor analgesia.
- Trial name
- NCT05487196
- Testing
- Clonidine, Dexmedetomidine, Fentanyl
- Where
- United States
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Grace Lim, MD, MS
Pain, Postoperative, Anesthesia, Local
Postoperative Pain Relief With Transversus Thoracis Muscle Plane Block After Cardiac Surgery
This study aims to investigate the effect of transversus thoracis muscle plane block (TTP), using repeated boluses of ropivacaine via catheter, on postoperative pain and oxycodone consumption after elective cardiac surgery with…
- Conditions
- Pain, Postoperative, Anesthesia, Local, Coronary Artery Disease, Heart Valve Diseases
- Trial name
- TTPcat (NCT04916418)
- Testing
- Ropivacaine
- Where
- Finland
- Volunteers
- 120 people
- Sponsor
- Turku University Hospital