Clinical trials: Ropivacaine
Arthroplasty
Continuous Adductor Canal Block (CACB) vs. Combined Spinal Epidural (CSE) in Total Knee Arthroplasty
Purpose: Compare continuous adductor canal block (CACB) to Combined Spinal Epidural (CSE) for total knee arthroplasty in terms of mobility, post-operative pain, and analgesic use.
- Trial name
- NCT02415465
- Testing
- Continuous Adductor Canal Block, General, Epidural
- Where
- United States
- Volunteers
- 157 people
- Sponsor
- Rush University Medical Center
Pain
Efficacy of the Transversus Abdominus Plane (TAP) Block for Post-Cesarean Delivery Analgesia
The purpose of this study is to determine if patients having the transversus abdominal place (TAP) block at the end of a cesarean delivery have less pain in the post-delivery period than those who do not.
- Trial name
- NCT00573963
- Testing
- ropivacaine, saline solution
- Where
- Canada
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Samuel Lunenfeld Research Institute, Mount Sinai Hospital
Brachial Plexus Block, Anesthetics, Local
Analgesic Duration of Long Acting Local Anesthetics for Low Volume Ultrasound-guided Interscalene Brachial Plexus Block
Severe pain following shoulder surgery is common and remains a major challenge. The interscalene nerve block is well suited for operations on the shoulder or upper arm, for providing surgical anesthesia as well as prolonged…
- Trial name
- NCT02643563
- Testing
- Ropivacaine 0.5%, Ropivacaine 1%, Bupivacaine 0.5% + epinephrine 1:200,000
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- Sunnybrook Health Sciences Centre
Hand Injuries and Disorders, Wrist Sprain
Perineural vs Intravenous Dexamethasone as an Adjuvant to Brachial Plexus Block in Pediatric Hand Surgery
This clinical trial will evaluate the neurological safety and analgesic effectiveness of dexamethasone administered perineurally or intravenously as an adjuvant to brachial plexus block in children undergoing hand or forearm…
- Trial name
- NCT07474909
- Testing
- iv dexamethasone, pn dexamethasone, 0.9%NaCl
- Where
- Poland
- Volunteers
- 150 people
- Sponsor
- Poznan University of Medical Sciences
Complex Regional Pain Syndromes
Thoracic Sympathetic Ganglion Block With Botulinum Toxin Type A
Thoracic sympathetic ganglion block is a percutaneous procedure that paralyzes the action of sympathetic nerves transiently by injecting a local anesthetic around the ganglion.
- Trial name
- NCT06470581
- Testing
- Botulinum toxin A
- Volunteers
- 78 people
- Sponsor
- Seoul National University
Post-operative Pain, Post-cardiac Surgery
Paravertebral Block for Improvement of Quality of Recovery Following Cardiac Surgery
This study aims to evaluate the efficacy of bilateral, paravertebral blockade (intervention) against sham blocks (control) placed prior to sternotomy in improving quality of recovery following cardiac surgery.
- Conditions
- Post-operative Pain, Post-cardiac Surgery, Cardiac Disease
- Trial name
- NCT06008821
- Testing
- Bilateral paravertebral block with 0.25% ropivicaine with 1:400,000 epinephrine
- Where
- Canada
- Volunteers
- 224 people
- Sponsor
- University of British Columbia
Osteoarthritis
Comparison of Femoral Nerve Catheter and Adductor Canal Block With Steroid Adjuvant in Total Knee Replacement (TKR)
We hypothesize continuous adductor canal block with steroid adjuvant would offer no inferior analgesics and rehabilitation ability than continuous femoral nerve block for postoperative patients receiving total knee arthroplasty.
- Trial name
- NCT01973530
- Testing
- adductor canal block, femoral nerve block
- Where
- Hong Kong
- Volunteers
- 80 people
- Sponsor
- Queen Elizabeth Hospital, Hong Kong
Post-surgical Pain, Total Knee Arthroplasty
Effects of Catheter Location on Postoperative Analgesia for Continuous Adductor Canal and Popliteal-Sciatic Nerve Blocks
Currently, continuous adductor canal and popliteal-sciatic nerve blocks are used commonly for lower extremity post-operative pain control, specifically for total knee arthroplasty and foot/ankle surgery, respectively.
- Conditions
- Post-surgical Pain, Total Knee Arthroplasty, Foot/Ankle Surgery, Catheterization for Postop Analgesia
- Trial name
- NCT02523235
- Testing
- ropivacaine 0.2%
- Where
- United States
- Volunteers
- 117 people
- Sponsor
- University of California, San Diego
Gastric Cancer
The Comparison Between Epidural and Intravenous Patient-controlled Analgesia for Laparoscopic Gastrectomy
This study was designed to assess the effectiveness of epidural patient-controlled analgesia compared to intravenous patient-controlled analgesia in patients undergoing laparoscopic gastrectomy.
- Trial name
- NCT02444897
- Testing
- Epidural PCA Ropivacaine, IV PCA Fentanyl+nefopam+Ramosetron
- Where
- South Korea
- Volunteers
- 60 people
- Sponsor
- Keimyung University Dongsan Medical Center
Postoperative Pain, Breast Cancer
Pectoral Nerve Blockade in Mastectomy
Our routine practice for patients undergoing mastectomy is to include paravertebral peripheral nerve blockade for postoperative analgesia.
- Trial name
- NCT01943240
- Testing
- Paravertebral nerve block: 4 mL ropivacaine 0.5% at each of six levels, 10 cc of 0.375% ropivacaine pectoral nerve block
- Where
- United States
- Sponsor
- Timothy R Petersen
Erectile Dysfunction
Randomized Trial of Ropivacaine & Bupivacaine for Inflatable Penile Prosthesis
The purpose of this research is to determine the effects of penile ring block for local anesthesia with liposomal bupivacaine vs ropivacaine mixture in subjects undergoing surgery for Penile Prosthesis Placement.
- Trial name
- ROVEX-IPP (NCT04801368)
- Testing
- Randomization of two local anesthetics.
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Postpartum Depression (PPD)
Intranasal Dexmedetomidine for Postpartum Depression Prevention
Brief Title: Intranasal Dexmedetomidine for Postpartum Depression Prevention: A Randomized Trial This study aims to evaluate the effect of intranasal dexmedetomidine (Dex) administered before combined spinal-epidural labor…
- Trial name
- NCT07501728
- Testing
- Dexmedetomidine
- Where
- China
- Volunteers
- 270 people
- Sponsor
- Chengdu Jinjiang Maternity and Child Health Hospital
Hip Osteoarthritis, Hip Pain Chronic
Continuous Radiofrequency in Hip Osteoarthritis Pain: A Randomized Clinical Trial.
This will be a prospective, single-center, double-blinded, randomized study designed to compare the efficacy of the intraarticular injection of a corticosteroid and the Conventional Radiofrequency (CRF) of the anterior sensory…
- Trial name
- NCT06221709
- Testing
- Conventional Radiofrequency (CRF group), Intraarticular Infiltration ( Control group)
- Where
- Brazil
- Volunteers
- 70 people
- Sponsor
- University of Brasilia
Postoperative Pain
QLESP Block in Hip Surgery
Total hip arthroplasty (THA) is a common surgical procedure aiming to improve mobility and quality of life in patients suffering from hip pain.
- Trial name
- NCT05998954
- Testing
- transmuscular quadratus lumborum and modified erector spinae plane (QLESP) block, suprainguinal fascia iliaca block
- Where
- China
- Sponsor
- Huazhong University of Science and Technology
Coronary Heart Disease
Studies of Application of Combined General Anesthesia and Bilateral TPVB in OPCABG
This study intends to compare the combination of general anesthesia (GA) and single-shot bilateral thoracic paravertebral block (TPVB) by ropivacaine in the patients undergoing off-pump coronary artery bypass surgery ( OPCAB)…
- Trial name
- NCT02727712
- Testing
- bilateral thoracic paravertebral block, Transesophageal Echocardiography（TEE）, Lung protection measure during the surgery（Dräger Primus）
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Xiangya Hospital of Central South University
Neurologic Disorder, Spastic Hemiplegia
Proximal Lower Limb Intramuscular Block : Effects on Hemiparetic Gait
To assess feasability, tolerance of anesthesic intramuscular motor block. To study immediate effects on differents muscles : gluteus maximus, rectus femoris in a hemiparetic population (over 15 days) To precise the role of the…
- Conditions
- Neurologic Disorder, Spastic Hemiplegia, Gait, Hemiplegic, Block
- Trial name
- ProxiBlock (NCT05519592)
- Testing
- Ropivacaine injection, Sodium Chloride Injection
- Volunteers
- 30 people
- Sponsor
- Henri Mondor University Hospital
Atrial Fibrillation
The Effect of Preoperative SGB on POAF After VATS
The aim of this study is to test if stellate ganglion block can decrease the incidence of atrial fibrillation after video-assisted thoracoscopic surgery and the way it works.
- Trial name
- NCT05753644
- Testing
- stellate ganglion blocks, Ropivacaine
- Where
- China
- Volunteers
- 480 people
- Sponsor
- Peking University People's Hospital
Postoperative Pain Management
Pain Treatment After TKA With LIA and Intra-articular Continuous Infusion Pump
The purpose of this study is to evaluate the effect on postoperative pain and function by adding intraarticular continuous infusion pump with local anesthetic after total knee arthroplasty where local infiltration analgesia has…
- Trial name
- NCT01726686
- Testing
- Ropivacaine
- Where
- Sweden
- Volunteers
- 200 people
- Sponsor
- Region Skane
Adolescent Idiopathic Scoliosis
Effect of Spinae Erector Block (ESP) and Gabapentin on Recovery and Length of Stay in Adolescent Spinal Fusion Patients
A retrospective cohort study comparing time to ambulation (hours) between two groups of adolescent spinal fusion patients: a group who received intravenous multimodal analgesic strategy alone (MMA group) and another group who…
- Trial name
- NCT06096480
- Testing
- gabapentin + bilateral spine erector block
- Where
- Argentina
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Hospital Italiano de Buenos Aires
Zoster Without Complications
Regional Anesthesia to Relief Zoster Pain
Pain in Herpes is a serious issue for patients. at the acute phase it is a moderate to severe pain . 30% patients will develop a post herpetic neuralgia this percentage up to 70 % after 60 years old.
- Trial name
- NCT04133142
- Testing
- peripheral nerve block, inter fascial nerve block
- Where
- Vietnam
- Sponsor
- Vinmec Healthcare System
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