Clinical trials: Sevoflurane, completed
Obstructive Sleep Apnea
Effect of Ketorolac on Post Adenotonsillectomy Pain
This randomized prospective study aims to determine the effect of ketorolac on the total dose of morphine required to achieve postoperative analgesia in children with obstructive sleep apnea (OSA) undergoing adenotonsillectomy.
- Trial name
- NCT03467750
- Testing
- Ketorolac, Standard of Care
- Where
- United States
- Volunteers
- 63 people
- Sponsor
- Emory University
Pain, Postoperative, Postoperative Complications
Open and Laparoscopic Total Extraperitoneal Repair Under Spinal Anesthesia Versus General Anesthesia
Inguinal hernia surgery is one of the most frequently performed procedures among general surgery cases. As with many open surgical methods, this repair is also performed laparoscopically.
- Conditions
- Pain, Postoperative, Postoperative Complications, Inguinal Hernia
- Trial name
- NCT05837013
- Testing
- Spinal anesthesia (with nerve block), General anesthesia (GA)
- Where
- Turkey (Türkiye)
- Volunteers
- 34 people
- Sponsor
- Konya City Hospital
Obesity, Anesthesia
Optimal Anesthesia for Morbidly Obese Patients
Obese patients have a higher risk of anesthesia compared to the non-obese, including difficult intubation, rapid desaturation, difficult vascular access, and delayed recovery from anesthesia.
- Trial name
- NCT04395248
- Testing
- Exploring potential risk factors of difficult intubation using ultrasound, Radial artery catheterization using ultrasound guidance or blind palpation, Comparing the effectiveness of preoxygenation between high-flow nasal cannula and facemask
- Where
- Taiwan
- Volunteers
- 80 people
- Sponsor
- Taipei Medical University Shuang Ho Hospital
Ambulatory Surgery, Anesthesia
Effects of Propofol on Early Recovery of Hunger After Surgery
Recovery of hunger is a source of comfort for patients after general anesthesia. Moreover, this aspect of post-operative period is often required for discharging patients from hospital after ambulatory surgery.
- Conditions
- Ambulatory Surgery, Anesthesia, Energy Expenditure, Food Intake
- Trial name
- Propo-Faim (NCT02272166)
- Testing
- propofol, Sevoflurane
- Where
- France
- Volunteers
- 116 people
- Sponsor
- University Hospital, Rouen
Intubation; Difficult
Nasotracheal Intubation Using Shikani Optical Stylet
Difficult airways is still a challenging issue for the anesthesiologists in spite of the development of various techniques.Shikani optical stylet(SOS), combining the features of fiberoptic bronchoscope and a lightwand, has been…
- Trial name
- SOS (NCT00963677)
- Testing
- Nasotracheal Intubation through seeing optical stylet (SOS)
- Where
- China
- Volunteers
- 55 people
- Sponsor
- Central South University
Myocardial Reperfusion Injury, Atrial Fibrillation
Inhaled Sevoflurane Compared to Intravenous Sedation Post Coronary Artery Bypass Grafting
Inhaled sevoflurane during coronary artery bypass grafting (CABG) reduces postoperative Troponin levels and may be associated with improved outcome.
- Trial name
- NCT00484575
- Testing
- Sevoflurane, propofol
- Where
- Sweden
- Volunteers
- 100 people
- Sponsor
- Karolinska Institutet
Rotator Cuff Tear Arthropathy
Vasopressin to Prevent Hypotension During Beach Chair Surgery
Patients undergoing surgery in beach chair position (BCP) are at risk for cerebral ischaemia. The impacts of arginine vasopressin (AVP) on haemodynamics and cerebral oxygenation are evaluated during surgery in BCP.
- Trial name
- NCT01687894
- Testing
- Vasopressins, propofol, sevoflurane
- Where
- South Korea
- Volunteers
- 74 people
- Sponsor
- Chonnam National University Hospital
Anesthesia
Bispectral Index and End-Tidal Anesthetic Gas Concentration in Pediatric Patients
The purpose of this study is to investigate the relationship between BIS™ values including EEG profile and anesthetic agents in the pediatric population
- Trial name
- BTIGER (NCT04810481)
- Testing
- BIS Complete Monitoring System
- Where
- 8 sites in United States
- Volunteers
- 209 people
- Sponsor
- Medtronic - MITG
Kidney Donation/Transplantation
"Volatile Anesthetic Protection Of Renal Transplants: VAPOR-1-trail
To compare the renal protective properties of two currently used anaesthetic techniques - a sevoflurane-remifentanil/sufentanil combination with a propofol-remifentanil/sufentanil combination for anaesthesia in patients…
- Trial name
- NCT01248871
- Testing
- procedure:sevoflurane-remifentanil/sufentanil, volatile agent only during reperfusion, propofol-remifentanil/sufentanil
- Where
- Netherlands
- Volunteers
- 120 people
- Sponsor
- University Medical Center Groningen
Intravenous Cannulation, Sevoflurane Induction
Intravenous Cannulation In Children During Sevoflurane Induction
The early placement of an intravenous (iv) line in children anesthetized with halothane has been shown safe and acceptable compared with later placement. However, there's not well known with sevoflurane use (2).
- Conditions
- Intravenous Cannulation, Sevoflurane Induction, Child
- Trial name
- NCT03851692
- Testing
- Intravenous Cannulation (iv placement)
- Volunteers
- 90 people
- Sponsor
- University Hospital Fattouma Bourguiba
Cardiac On-pump Surgery
Organ Protection With Sevoflurane Postconditioning After Cardiac Surgery With Cardiopulmonary Bypass
Organ protection, volatile anesthetics, postconditioning. Sedation of patients on ICU after cardiac surgery with cardiopulmonary bypass with either propofol or sevoflurane.
- Trial name
- NCT00924222
- Testing
- Sevoflurane, Propofol
- Where
- Switzerland
- Volunteers
- 120 people
- Sponsor
- University of Zurich
Intraocular Pressure, Anesthesia
Intraocular Pressure in Patients Undergoing Coronary Artery Bypass Graft Surgery With Cardiopulmonary Bypass
The aim of the study to compare the effects of sevoflurane-based anesthesia and propofol-based total intravenous anesthesia on intraocular pressure (IOP) during coronary artery bypass graft surgery (CABG) with cardiopulmonary…
- Trial name
- NCT06494969
- Testing
- Intraocular pressure measurement
- Where
- Turkey (Türkiye)
- Volunteers
- 65 people
- Sponsor
- Antalya Training and Research Hospital
Caesarean Section, Pregnancy
Modern Myorelaxation Procedure and Reversal of Neuromuscular Blockade With General Anesthesia for Caesarean Section
The project aims to introduce into clinical practice for Caesarean section conducted under general anesthesia with the rapid induction myorelaxation with rocuronium and the reversal of neuromuscular blockade by using sugammadex.
- Trial name
- RocSugIO (NCT01718236)
- Testing
- Rocuronium + sugammadex, Succinylcholine + Neostigmine
- Where
- 2 sites in Czechia
- Volunteers
- 500 people
- Sponsor
- Brno University Hospital
Pain, Postoperative, Phimosis
An Evaluation of Pain Outcomes of Ketorolac Administration in Children Undergoing Circumcision
Circumcision is the most common surgical procedure performed by Pediatric Urologists. Ketorolac has been shown to have an efficacy similar to morphine in multi-modal analgesic regimens without the commonly associated adverse…
- Conditions
- Pain, Postoperative, Phimosis, Paraphimosis, Balanitis
- Trial name
- NCT04646967
- Testing
- Bupivacain, Sevoflurane, Acetaminophen
- Where
- Canada
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Alberta Children's Hospital
Anesthesia
A Pilot Study to Investigate Plasma Bupivacaine Concentrations in Children Receiving Total Intravenous Anaesthesia and Caudal Analgesia
The objective of this pilot study is to compare plasma [bupivacaine] between two groups of paediatric patients under general anaesthesia who will all receive regional caudal anaesthesia with bupivacaine: group 1 will receive TIVA…
- Trial name
- NCT01216007
- Testing
- propofol, sevoflurane
- Where
- Canada
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Anesthesia, Geriatric Patients
The Effect of Anesthesia Type on Pulmonary Function
The role of neuraxial anesthesia in preventing respiratory complications is a controversial in elderly patients. The aim of the study was to evaluate the benefits of neuraxial anesthesia on pulmonary function during…
- Trial name
- NCT03399201
- Testing
- General anesthesia, Neuraxial anesthesia, Spirometer
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Tokat Gaziosmanpasa University
Thoracic Surgery, Cardiopulmonary Bypass
Protection During Cardiac Surgery.
This trial investigates whether a multimodal cardioprotection per-surgery therapeutic strategy could reduce myocardial injury in patients undergoing cardiac surgery compared to traditional management.
- Trial name
- ProCCard (NCT03230136)
- Testing
- multimodal cardioprotection strategy, standard anesthetic procedure
- Where
- 8 sites in France
- Volunteers
- 210 people
- Sponsor
- Hospices Civils de Lyon
Smell Functions, Odor Memory
Effects of Different Anesthesia on Odor Memory
This study aimed to research the effect of different general anesthesia administration on postoperative smell functions and memory.
- Trial name
- NCT05499845
- Testing
- butanol threshold test and smell identification tests
- Where
- Turkey (Türkiye)
- Volunteers
- 97 people, healthy volunteers welcome
- Sponsor
- Zonguldak Bulent Ecevit University
Turbinate Surgery, Sphenopalatine Block
Blocking Sphenopalatine Ganglion by Intranasal Lidocaine Spray in Partial Turbinectomy Surgeries
Nasal turbinectomy surgeries are usually done as day case surgeries as most patients are young with unremarkable comorbidities. However, considerations are still present towards patients of old age or those suffering from obesity…
- Trial name
- SPG block (NCT07299630)
- Testing
- Balanced anesthesia, Lidocaine spray
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Ain Shams University
Cytokines, Inflammatory
Cytokines and Sevoflurane During Surgery
The aim of the present study was to evaluate the effects of anaesthesia with sevoflurane and surgery on cytokines response.
- Conditions
- Cytokines, Inflammatory, Sevoflurane
- Trial name
- NCT01231477
- Where
- Brazil
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- UPECLIN HC FM Botucatu Unesp