Clinical trials: Sevoflurane, completed
Cardiac Surgery
Evaluate the Protective Effect of Conditioning With Sevoflurane on the Myocardium
Heart surgery is a considerable source of stress for the myocardium that must be minimized. Troponin Ic is a reliable marker to determine the level of this myocardial stress.
- Trial name
- SUPRA (NCT02851433)
- Testing
- total anaesthesia and postoperative inhaled sedation with Sevoflurane, total intravenous anaesthesia with Propofol.
- Where
- France
- Volunteers
- 82 people
- Sponsor
- Centre Hospitalier Universitaire Dijon
Strabismus
Propofol Versus Sevoflurane Anesthesia in Pediatric Strabismus Surgery: Feasibility of BIS Monitoring
This study is conducted to evaluate importance of bispectral index (BIS) monitoring in patients undergoing strabismus surgery when using propofol in comparison to sevoflurane anesthesia regarding their effects on oculocardiac…
- Trial name
- NCT04485117
- Testing
- Bispectral Index Monitor, Laryngeal Mask Airway, Sevoflurane
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Sameh Fathy
Adverse Effect of Drugs and Medicaments in Therapeutic Use, Adverse Effects in the Therapeutic Use of Anaesthetics
The Effect of Opioid Free Anesthesia in Bariatric Surgeries
This is a prospective randomized controlled study that will be carried out on morbid obese patients admitted to Tanta University hospitals for laparoscopic bariatric surgeries.
- Trial name
- Opioidfree (NCT04048200)
- Testing
- Fentanyl, Dexmedetomidine Ketamine
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Tanta University
Postoperative Pain
The Effect of Esketamine on Postoperative Pain Relief in Patients Undergoing Laparoscopic Surgery
The purpose of this study is to investigate whether continuous intraoperative infusion of esketamine combined with the addition of esketamine to postoperative PCIA can improve postoperative pain and sleep quality in patients…
- Trial name
- NCT06300944
- Testing
- saline, Esketamine
- Where
- China
- Volunteers
- 100 people
- Sponsor
- General Hospital of Ningxia Medical University
Anesthesia, Anesthesia; Adverse Effect
Co-induction Technique Compared to Standard Inhalational and Intravenous Induction Techniques
Co-induction technique refers to the use of a combination of medications to reach the desired therapeutic target. In the present study, the investigators examined the safety of a novel co-induction approach that relied on a…
- Trial name
- NCT04284644
- Testing
- Induction using propofol, Induction using sevoflurane, Induction using propofol and sevoflurane
- Where
- Jordan
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- University of Jordan
General Anesthesia
Safety and Efficacy of Maintenance of Etomidate in General Anesthesia
This study was designed to use etomidate combined with sevoflurane intravenously to maintain anesthesia process under the monitoring of BIS. Propofol was used as the controls.
- Trial name
- NCT05223907
- Testing
- Etomidate, Propofol
- Where
- China
- Volunteers
- 1,080 people
- Sponsor
- Henan Provincial People's Hospital
Strabismus
Effect of Remifentanil on Postoperative Vomiting in Pediatric Strabismus Surgery
The purpose of this study is to compare the effect of remifentanil on postoperative vomiting in children undergoing strabismus surgery during sevoflurane anesthesia.
- Trial name
- NCT02455401
- Testing
- High dose remifentanil, Low dose remifentanil, No remifentanil
- Where
- South Korea
- Volunteers
- 60 people
- Sponsor
- Inje University
Ventilation, Laryngeal Mask Airway
Impact of Different Modes of Ventilation With Laryngeal Mask Airway on Pediatric Cataract Surgery
This study will be conducted to evaluate effects of different modes of ventilation on pediatric cataract surgery aiming to a peri-operative stable anesthesia, better surgical satisfaction and post operative recovery.
- Conditions
- Ventilation, Laryngeal Mask Airway, Cataract Surgery
- Trial name
- NCT04241653
- Testing
- Pressure Support Ventilation, Unparalyzed Pressure Control Ventilation, Paralyzed Pressure Control Ventilation
- Where
- Egypt
- Volunteers
- 150 people
- Sponsor
- Sameh Fathy
General Anesthesia
Comparison of Two Electroencephalograms (EEG) Monitors in Patients Undergoing General Anesthesia With Sevoflurane
Quantium Medical Company has an ElectoEcenphalograph-based (EEG-based) algorithm with two outputs: qCON for unconsciousness and qNOX for anti-nociception.
- Trial name
- Bis-qCon-Hal (NCT03359512)
- Testing
- qCON monitor
- Where
- France
- Volunteers
- 46 people
- Sponsor
- Hopital Foch
General Anesthesia, Sevoflurane
Efficacy and Safety of Sevofran in Patients Scheduled for Elective Surgery Under General Anesthesia
Sevoflurane is currently being used in more than 100 countries worldwide with an estimated 100 million operations having been performed using sevoflurane as a general anesthetic.
- Conditions
- General Anesthesia, Sevoflurane, Generic Drugs
- Trial name
- NCT01096212
- Testing
- original sevoflurane, generic sevoflurane
- Where
- 2 sites in South Korea
- Volunteers
- 178 people
- Sponsor
- Asan Medical Center
Pediatric Population, Preoperative Anxiety
Comparing the Effectiveness of Virtual Reality in Paediatric Patients
To the best of our knowledge,the investigators found only a study using VR in reducing preoperative anxiety in paediatric population.
- Trial name
- NCT06044753
- Testing
- Virtual Reality Headset
- Where
- Malaysia
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Universiti Kebangsaan Malaysia Medical Centre
Anesthesia, Surgery
Hypercapnic Spontaneous Hyperpnoea and Recovery From Sevoflurane Anesthesia
The rate of elimination of inhalation agent is directly proportional to the degree of alveolar ventilation. Using Isocapnic Hyperpnoea (IH) device, it is possible to maintain constant end-tidal CO2 with increased minute…
- Trial name
- NCT01151267
- Testing
- Standard Anesthesia management for post surgical patients, Hypercarbic Spontaneous Hyperpnoea
- Where
- Canada
- Volunteers
- 44 people
- Sponsor
- University Health Network, Toronto
Renal Failure
Desflurane vs. Sevoflurane in Endovascular Aortic Repair
Randomized Clinical Trial following the evaluation of the impact on renal function in patients undergoing endovascular aortic aneurysm repair with two anesthetics protocols (Desflurane versus Sevoflurane) on the first 24 hours…
- Trial name
- NCT03917186
- Testing
- Sevoflurane, Desflurane
- Where
- Spain
- Volunteers
- 80 people
- Sponsor
- Begoña Quintana Villamandos
Breast Cancer
The Impact of Intravenous Anaesthesia on Angiogenesis in Patients With Breast Cancer (TIVA/TCI-BC)
Because neoplastic disease is one of the leading causes of death worldwide and breast cancer is one of the most frequent neoplasia among women, the possibility of influencing the evolution of patients starting from the moment of…
- Trial name
- TIVA/TCI-BC (NCT02839668)
- Testing
- Lidocaine, Sevoflurane, TIVA-TCI
- Where
- Romania
- Volunteers
- 120 people
- Sponsor
- Iuliu Hatieganu University of Medicine and Pharmacy
Laparoscopic General, Gynecological and Urologic Surgeries
Evaluation of the Sevoflurane Consumption During General Anesthesia When Using the MemsorbTM Membrane
The study aims at determining whether replacing the classical chemical absorber Dräegersorb 800+ on Dräeger Perseus A500 machines (Dräeger, Lübeck, Germany) by the new membrane technology-based product (Memsorb™, DMF Medical…
- Trial name
- MEMSEV (NCT04539405)
- Testing
- To evaluate sevoflurane consumption when using Memsorb, To evaluate sevoflurane consumption when using classical Dräegersorb
- Where
- Canada
- Volunteers
- 50 people
- Sponsor
- Ciusss de L'Est de l'Île de Montréal
Lung Function
Effect of Total Intravenous Anesthesia and Balanced Anesthesia on Postoperative Lung Function
The aim of the study is to investigate the effects of total intravenous anesthesia (TIVA; propofol, remifentanil) and balanced anesthesia (BAL; induction with propofol and fentanyl; maintenance of anesthesia with sevoflurane and…
- Trial name
- NCT00706277
- Testing
- propofol, remifentanil, fentanyl
- Where
- Austria
- Volunteers
- 60 people
- Sponsor
- Medical University Innsbruck
Atelectasis, General Aneshesia
Effects of Anesthesia on Atelectasis
We know that respiratory functions of patients are affected under general anaesthesia. Although there are many underlying causes of ventilation-perfusion mismatch in the airways, the main cause is atelectasis during general…
- Trial name
- NCT06790901
- Testing
- LUNG ULTRASOUND
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Zonguldak Bulent Ecevit University
Hypoxic Pulmonary Vasoconstriction, Hypoxemia
Effects in Oxygenation and Hypoxic Pulmonary Vasoconstriction in ARDS Secondary to SARS-CoV2
Summary Currently, the COVID-19 pandemic has overtaken health systems worldwide, exceeding the capacity of intensive care units.
- Conditions
- Hypoxic Pulmonary Vasoconstriction, Hypoxemia, Acute Respiratory Distress Syndrome, SARS-CoV-2 Acute Respiratory Disease
- Trial name
- COVID-19 (NCT04998253)
- Testing
- Effects in oxygenation and hypoxic pulmonary vasoconstriction
- Where
- Mexico
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Unidad Temporal COVID-19 en Centro Citibanamex
Anesthesia, Pediatrics
Chocolate or Sevoflurane: Use of Parosmia to Facilitate More Cooperative Inhalation Inductions in Children
Children undergoing surgery and anesthesia are often negatively impacted by anxiety and fear in the preoperative period. Routine inhalational anesthetic induction is a unique aspect of pediatric anesthesia.
- Trial name
- NCT06449157
- Testing
- Inhalation induction with parosmia
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Johns Hopkins University
Pain, Postoperative, Pain
Monitor-Guided Analgesia During General Anesthesia - Part II
This prospective randomized clinical trial evaluates the effects of a monitor-guided opioid analgesia during general anesthesia.
- Conditions
- Pain, Postoperative, Pain, Nociceptive Pain, Opioid Use
- Trial name
- MOGADA-II (NCT03380949)
- Testing
- Opioid administration (remifentanil) in intervention group, Opioid administration (remifentanil) in control group
- Where
- Germany
- Volunteers
- 96 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf