Clinical trials: Transcranial Direct Current Stimulation
Healthy, Schizophrenia
Modulating Human Cortical Plasticity With Transcranial Electrical Stimulation
Experience dependent plasticity is a fundamental property of the brain. It allows neural systems to adapt in response to environmental input and subserves the vital functions of learning and memory.
- Trial name
- NCT03114488
- Testing
- tDCS
- Where
- United States
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Tinnitus
MaST: MEG and Brain Stimulation in Tinnitus
Tinnitus is the awareness of a sound in the ear or head without any outside source. It affects around 15% of people in the UK. About 20% of people with tinnitus experience symptoms that negatively affect their quality of life…
- Trial name
- MaST (NCT04978142)
- Testing
- transcranial Direct Current Stimulation (tDCS)
- Where
- United Kingdom
- Volunteers
- 40 people
- Sponsor
- University of Nottingham
Stroke
Noninvasive Dual-mode Stimulation Therapy for Neurorehabilitation in Stroke
Repetitive transcranial magnetic stimulation (rTMS) or transcranial direct current stimulation (tDCS) has been used for the modulation of stroke patients' motor function by altering the cortical excitability.
- Trial name
- NCT03390192
- Testing
- Dual-mode stimulation
- Where
- South Korea
- Volunteers
- 43 people
- Sponsor
- Samsung Medical Center
Tinnitus, Subjective, Hyperacusis
Treatment of Tinnitus With Noninvasive Neuromodulation and Listening Therapy
The goal of this study is to use non-invasive transcranial direct current stimulation (tDCS) combined with active listening therapy to treat tinnitus and hyperacusis and related conditions.
- Conditions
- Tinnitus, Subjective, Hyperacusis, Hearing Disorders
- Trial name
- TDCS (NCT04934371)
- Testing
- Transcranial Direct Current Stimulation (tDCS)
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of Arizona
Lumbar Spinal Stenosis
Effectiveness of Transcranial Direct Current Stimulation in Chronic Pain Related to Lumbar Spinal Stenosis
Transcranial Direct Current Stimulation (tDCS) is a promising non-invasive brain stimulation technique in chronic pain. There is no study investigating the effectiveness of tDCS in radiating chronic lower extremity pain related…
- Trial name
- NCT03958526
- Testing
- active tDCS
- Where
- Turkey (Türkiye)
- Volunteers
- 32 people
- Sponsor
- Istanbul University
Chronic Aphasia
Effects of tDCS Versus HD-tDCS for Stroke Rehabilitation
The purpose of this study is to assess the changes in language processing of patients with chronic aphasia after receiving non-invasive brain stimulation.Previous research using traditional transcranial direct current stimulation…
- Trial name
- tDCS- Aphasia (NCT01651884)
- Testing
- HD-tDCS (Soterix), Transcranial Direct Current Stimulation (Neuroconn)
- Sponsor
- Soterix Medical
Alzheimer Disease
Transcranial Alternating Current Stimulation Combined With 40Hz Sound Stimulation for Treatment Alzheimer's Disease
Alzheimer's disease is characterized by progressive cognitive decline, and cognition is associated with cerebral concussion. Previous studies have found reduced gamma energy in the brain of AD patients.
- Trial name
- NCT05251649
- Testing
- tACS combined with 40 Hz sound stimulation, Transcranial alternating current stimulation, 40 Hz sound stimulation
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Chinese PLA General Hospital
Multitasking Behavior
At-home Transcranial Alternating Current Stimulation During Multitasking
The goal is to replicate in-lab results from transcranial alternating current stimulation (tACS) with at-home tACS.
- Trial name
- NCT04231825
- Testing
- Transcranial alternating current stimulation
- Where
- United States
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Stroke, Deficit in Manual Activities
Improving Bi-manual Activities in Stroke Patients With Application of Neuro-stimulation
Noninvasive brain stimulations (NIBS) will be used in healthy volunteers and in chronic stroke patients to improve bimanual activities and motor learning.
- Trial name
- NCT02308852
- Testing
- tDCS
- Where
- Belgium
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University Hospital of Mont-Godinne
Hemorrhagic Stroke, Hemiparesis
Dual Transcranial Direct Current Stimulation (dTDCS)-Enhanced Therapy After Hemorrhagic Strokes and VEGF
This study will evaluate the feasibility of dual tDCS to improve arm motor function in chronic stroke patients. In addition it will collect pilot data on the blood biomarkers associated with treatment effect.
- Trial name
- NCT03857243
- Testing
- dual transcranial direct current stimulation
- Where
- United States
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Neuropathic Pain, Phantom Limb Pain
Mindful SensoriMotor Therapy With Brain Modulation in Highly Impaired Extremities
Brief summary: This single-arm, pilot clinical investigation aims to evaluate Mindful SensoriMotor Therapy (MSMT) enhanced with brain modulation as a treatment of pain due to sensorimotor impairment, such as Phantom Limb Pain…
- Trial name
- NCT04897425
- Testing
- Mindful SensoriMotor Therapy Enhanced with Brain Modulation
- Where
- Sweden
- Volunteers
- 8 people
- Sponsor
- Chalmers University of Technology
Alzheimer's Disease
Neurostimulation and Cognitive Intervention in Alzheimer's Disease
This study is a double blind, sham-controlled clinical trial aiming to compare the long-term effects of stimulation in Alzheimer's Disease (AD).
- Trial name
- NeuroAD (NCT02772185)
- Testing
- active tDCS, real CT
- Where
- Brazil
- Volunteers
- 60 people
- Sponsor
- Federal University of Paraíba
Infantile Hemiplegia
HEMI-STIM. tDCS and Intensive Therapies
Application of Transcranial Direct Current or placebo combined with Constraint Induced Movement Therapy (CIMT) and bimanual intensive therapy (BIT) in infantile hemiplegia (4-8 years).
- Trial name
- NCT05226910
- Testing
- tDCS and intensive therapies
- Where
- Spain
- Volunteers
- 18 people
- Sponsor
- University of Castilla-La Mancha
Chronic Pain, Post Traumatic Stress Disorder (PTSD)
Transcranial Direct Current Stimulation Treatment for Warriors Experiencing Chronic Pain
The Veteran population has been known to deal with co-morbid chronic pain and PTSD. As a result, they use healthcare services at a higher rate than those Veterans with pain or PTSD alone which leads to an amplified burden on…
- Conditions
- Chronic Pain, Post Traumatic Stress Disorder (PTSD), Depression
- Trial name
- Warriors (NCT05254379)
- Testing
- tDCS
- Where
- United States
- Volunteers
- 38 people
- Sponsor
- Emory University
Epilepsy
Direct Cortical Measurement of the Intensity and Pattern of Current Flow Produced by TDCS
The primary study objective is to measure the electrical fields evoked by tDCS using subjects who have implanted intracranial electrodes as part of their evaluation for epilepsy surgery.
- Trial name
- NCT02263274
- Testing
- Transcranial Direct Current Stimulation (TDCS)
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- NYU Langone Health
Schizophrenia;Schizoaffective
The Effects of Non-invasive Brain Stimulation on Treatment Adherence in Schizophrenia
This study seeks to explore the effects of transcranial direct current stimulation (tDCS), a non-invasive method of brain stimulation, as an adjunctive treatment to improve antipsychotic medication adherence in patients with…
- Trial name
- NCT04033679
- Testing
- Active TDCS
- Where
- Canada
- Volunteers
- 106 people
- Sponsor
- Centre for Addiction and Mental Health
Mild Cognitive Impairment, Alzheimer's Disease
Promoting Adaptive Neuroplasticity in Mild Cognitive Impairment
The aging US population threatens to overwhelm our healthcare infrastructure, especially since the rate of Alzheimer's disease (AD) alone is expected to triple in the coming decades.
- Trial name
- NCT02155946
- Testing
- Transcranial direct current stimulation (tDCS) Soterix Medical Inc. tDCS unit
- Where
- United States
- Volunteers
- 107 people
- Sponsor
- VA Office of Research and Development
Consciousness Disorder, Brain Injuries
Neural, Behavioural, and Clinical Effects of tDCS in PDOC; Feasibility Study
This study evaluates the feasibility of an experimental protocol that combines advanced multi-modal imaging of the brain with clinical and behavioural scales to characterise the neural, behavioural, and clinical effects of…
- Conditions
- Consciousness Disorder, Brain Injuries, Vegetative State, Minimally Conscious State
- Trial name
- RAINDROP (NCT04248946)
- Testing
- Transcranial direct current stimulation
- Where
- 2 sites in United Kingdom
- Volunteers
- 15 people
- Sponsor
- University of Birmingham
Craving
The Effectiveness of Transcranial Direct Current Stimulation (tDCS) in Decreasing Food Cravings
This study aims to evaluate the effectiveness of transcranial direct current stimulation (tDCS) in decreasing food cravings. Specifically, this study will determine whether healthy subjects will report decreased food craving…
- Trial name
- NCT01030289
- Testing
- real tDCS
- Where
- United States
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
Anxiety
Biological and Psychological Markers After Intervention in Adults With GAD
This clinical trial inestigates the effects of transcranial direct current stimulation (tDCS) on anxiety symptoms in adult women with clinically relevant anxiety levels.
- Trial name
- AnsitDCS (NCT07116980)
- Testing
- 'Transcranial Direct Current Stimulation - tDCS
- Where
- Brazil
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Hospital de Clinicas de Porto Alegre
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