Clinical trials: Transcranial Magnetic Stimulation
Spatial Navigation
Modulating Goal-directed Navigation Using Noninvasive Brain Stimulation
Our specific aim is to examine the effects of TMS on spatial processing during goal-directed navigation. In these experiments the investigators will utilize a scalp-recorded brain oscillation called right posterior theta that is…
- Trial name
- NCT05801861
- Testing
- Active 10-Hz TMS to the parietal cortex, Active single pulse TMS to the parietal cortex
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Rutgers, The State University of New Jersey
Borderline Personality Disorder
Effect of Repeated Transcranial Magnetic Stimulation on Aggressive Impulsive Behavior in Patients With Borderline Personality Disorder in a Social Exclusion Paradigm.
Patients with a main diagnosis of borderline personality disorder will be recruited and will be randomized for the application of low frequency repeated transcranial magnetic stimulation (rTMS) protol or sham rTMS protocol.
- Trial name
- NCT04722510
- Testing
- repeated transcranial magnetic stimulation
- Where
- Mexico
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Instituto Nacional de Psiquiatría Dr. Ramón de la Fuente
PTSD - Post Traumatic Stress Disorder
Intermittent Theta-Burst Stimulation (iTBS) as an add-on to Eye Movement Desensitization and Reprocessing (EMDR) in the Treatment of Post-traumatic Stress Disorder (PTSD)
This open-label pilot study will evaluate the feasibility, safety, tolerability, and preliminary clinical outcomes of adding intermittent theta-burst stimulation (iTBS) to Eye Movement Desensitization and Reprocessing (EMDR)…
- Trial name
- NCT07693088
- Testing
- Intermittent Theta-Burst Stimulation (iTBS)
- Where
- 3 sites in Denmark
- Volunteers
- 15 people
- Sponsor
- Aarhus University Hospital
Chronic Neuropathic Pain
Study of RTMS Analgesic Effect in Chronic Neuropathic Pain,
The purpose of this study is to compare the analgesic effectiveness of three modes of repetitive Transcranial Magnetic Stimulation (rTMS) in chronic neuropathic pain: Classical rTMS stimulation Deeper rTMS stimulation Sham rTMS…
- Trial name
- NEUROSTIM (NCT04936646)
- Testing
- RepetitiveTranscranial Magnetic Stimulation (rTMS)
- Where
- France
- Volunteers
- 45 people
- Sponsor
- University Hospital, Grenoble
Spinal Cord Injury
Neuromodulation to Improve Grasping Function After SCI
The goal of this study is to restore the activities of late descending signals with a noninvasive stimulation approach in combination with hand motor training to improve hand function in persons with cervical SCI.
- Trial name
- NCT07433959
- Testing
- iTBS, PCMS, Exercise
- Where
- United States
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- State University of New York at Buffalo
Major Depressive Disorder, Depression
rTMS for MDD: 5.5cm Rule vs. F3 Targeting
The purpose of this study is to examine the effects of different treatment locations using repetitive transcranial magnetic stimulation (rTMS) to treat major depressive disorder.
- Trial name
- NCT03378570
- Testing
- Repetitive transcranial magnetic stimulation
- Where
- United States
- Volunteers
- 123 people
- Sponsor
- Nicholas Trapp
Provoked Vestibulodynia
Is Low Level Laser Therapy (LLLT) Effective for Reducing Pain Experienced by Women With Provoked Vestibulodynia?
Provoked vestibulodynia (PVD) is one major subtype of vulvar pain, affecting close to one in ten women and resulting in pain during attempts at vaginal intercourse and/or attempts to insert a digit, device or tampon into the…
- Trial name
- NCT04234542
- Testing
- Low Level Laser Therapy
- Where
- Canada
- Volunteers
- 28 people
- Sponsor
- University of Ottawa
Treatment Resistant Major Depression
Establishing Mobile Transcranial Magnetic Stimulation
In this pilot study, investigators propose to design and create a portable TMS unit, in a van, and then test out delivering TMS in three different locations in South Carolina, all affiliated with MUSC and within 2-hours driving…
- Trial name
- TMS (NCT06748209)
- Testing
- Left prefrontal Transcranial Magnetic Stimulation (TMS), FDA cleared TMS for treating depression
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Medical University of South Carolina
Depression
Using rTMS to Treat Depression
Repetitive Transcranial Magnetic Stimulation (rTMS) is a promising, novel, non-invasive therapy for depression. In fact, there is an FDA-approved depression protocol to stimulate the dorsolateral prefrontal cortex (dlPFC).
- Trial name
- NCT05424224
- Testing
- MagVita
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Florida International University
Lower Back Pain Chronic
Trial to Test the Efficacy of Using Magnetic Fields to Stimulate the Back to Treat Chronic Lower Back Pain.
The goal of this study is to see if a new way to treat back pain without the use of medications is effective. We plan use Transcranial Magnetic Stimulation (TMS), a wand-like device, to excite the nerves of people with lower back…
- Trial name
- NCT07652944
- Testing
- peripheral magnetic stimulation, Home exercise
- Where
- United States
- Volunteers
- 88 people
- Sponsor
- Joe X. Zhang
Parkinson, Dystonia
Sensorimotor Integration in Monogenic Parkinson-dystonia Syndromes
Hereditary Parkinson and dystonia syndromes are rare, as are people who carry the predisposition for Parkinson or dystonia but do not have symptoms.
- Conditions
- Parkinson, Dystonia, DYT3, DYT5
- Trial name
- SensoMo-PD (NCT05713721)
- Testing
- Transcranial magnetic stimulation (TMS), Video-based clinical examination, 24 hours drug withdrawal of dopaminergic medication
- Where
- Germany
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University Hospital Schleswig-Holstein
Postoperative Delirium
EEG-TMS Intervening Against Postoperative Delirium
Postoperative delirium is common in elderly surgical patients and is associated with complications and prolonged hospitalisation.
- Trial name
- RECOVER (NCT07100197)
- Testing
- continuous Theta-burst stimulation
- Where
- China
- Volunteers
- 98 people
- Sponsor
- RenJi Hospital
Kinesiophobia, Motor Coordination or Function; Developmental Disorder
Influence of Kinesiophobia on the Excitability of Connections Parieto-frontal During a Pointing Movement in Humans
Objective(s) of the trial: Better understand the interaction between kinesiophobia and motor control. Main objective: To measure the influence of induced kinesiophobia on functional connectivity between the posterior…
- Conditions
- Kinesiophobia, Motor Coordination or Function; Developmental Disorder, Transcranial Magnetic Stimulation, Pain, Acute
- Trial name
- pIPS/M1 (NCT06125613)
- Testing
- Experimental
- Where
- France
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Universite du Littoral Cote d'Opale
Neuropathic Pain
Cortical Plasticity After Motor Cortex Stimulation in Healthy Subject and Chronic Pain Patients
The primary aim of this study is to evaluate the induction of sensory-motor cortex plasticity after motor cortex stimulation in healthy subjects, using laser-evoked nociceptive cortical potentials, and in chronic neuropathic pain…
- Trial name
- NCT02849834
- Testing
- Repetitive Transcranial Magnetic Stimulation (rTMS)
- Where
- France
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- Hospices Civils de Lyon
Impaired Insight
Targeted Intervention Study of DTMS on Impaired Insight in Early Psychosis
Impaired insight is a key factor in the conversion of high-risk individuals to schizophrenia, but there is a lack of targeted interventions.
- Trial name
- NCT04513132
- Testing
- active-dTMS
- Where
- China
- Sponsor
- Shanghai Mental Health Center
Post-stroke Spasticity of the Upper Limb
TMS AND BOTULINUM TOXIN IN POST-STROKE UPPER LIMB SPASTICITY
Post-stroke upper limb spasticity is an important condition that negatively affects motor recovery, upper limb functions, and activities of daily living.
- Trial name
- TMS (NCT07624149)
- Testing
- Repetitive Transcranial Magnetic Stimulation (rTMS), Continuous Theta Burst Stimulation (cTBS)
- Where
- Turkey (Türkiye)
- Volunteers
- 39 people
- Sponsor
- Asya ÖZCAN KAVCI
Depressive Disorder, Treatment-Resistant
rTMS With and Without Text4Support for the Treatment of Resistant Depression.
This study is a multicenter prospective, parallel design, two-arm, rater-blinded randomized controlled pilot trial. Participants will be randomly assigned to one of two treatment conditions.
- Trial name
- NCT05570344
- Testing
- Repetitive Transcranial Magnetic Stimulation (rTMS), Repetitive Transcranial Magnetic Stimulation (rTMS) Plus Text4Support
- Where
- 2 sites in Canada
- Volunteers
- 200 people
- Sponsor
- University of Alberta
Depression
Theta Burst Stimulation in Pharmacologically Untreated Patients as Sole Antidepressant Treatment
This is a randomized, controlled trial in which 72 patients with depressive disorder were treated in two study arms using the non-invasive brain stimulation method of intermittent thetaburst intermittent theta burst stimulation…
- Trial name
- TRUST (NCT05732298)
- Testing
- intermittend theta burst stimulation (iTBS)
- Where
- Germany
- Volunteers
- 72 people
- Sponsor
- University of Regensburg
Obsessive-Compulsive Disorder
Evaluation of the Long Term Efficacy and Durability of the BrainsWay Deep TMS in OCD Subjects
A Prospective Double Blind Randomized Controlled Trial to Evaluate the Long Term Efficacy and Durability of the BrainsWay Deep Transcranial Magnetic Stimulation (Deep TMS) in Obsessive-Compulsive Subjects
- Trial name
- NCT05404360
- Testing
- BrainsWay Deep TMS HAC/H7-Coil
- Volunteers
- 124 people
- Sponsor
- Brainsway
Aphasia
TMS in Aphasia Recovery
Stroke often causes substantial problems in speaking or understanding speech. Treatments for these problems are currently very limited.
- Trial name
- NCT04777214
- Testing
- Repetitive Transcranial Magnetic Stimulation
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- University of Pennsylvania
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