Clinical trials: Transcranial Magnetic Stimulation
Fibromyalgia
An Exploration of the Neuroplasticity of Endogenous Analgesia in Health and Chronic Pain
Transcranial magnetic stimulation (TMS) is a neurophysiological tool for studying cortical functions, and in addition, has an analgesic therapeutic effect whose underlying mechanism is unknown.
- Trial name
- NCT02572726
- Testing
- active repeated transcranial magnetic stimulation
- Where
- Israel
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Rambam Health Care Campus
Cerebrovascular Disease
Comparing Effects of Various Combinations of 6 Hertz(Hz) rTMS & LFrTMS on Motor Recovery Due to Cerebrovascular Disease
To compare the effects of various combinations between 6 hertz(Hz) rTMS \& LFrTMS on the limb motor dysfunction due to cerebral vascular disease.
- Trial name
- NCT03012204
- Testing
- real LFrTMS at unaffected M1, real primed LFrTMS at unaffected M1, combined rTMS at both M1
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Beijing Hospital
Healthy
Probing TBS-induced Neural Plasticity and Associated Effects on Learning
Recent animal research indicates that excitatory brain stimulation opens a time window of increased neural plasticity that permits remodeling of neural representations.
- Trial name
- NCT03756584
- Testing
- Theta-burst stimulation
- Where
- Hong Kong
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Dr Georg Kranz
Healthy, EEG
EEG Analytics to Determine Effectiveness of a tDCS Protocol
The goal of this study is to monitor the brain using electroencephalography (EEG) while transcranial direct current stimulation (tDCS) is being administered, as a potential pathway to determine neurophysiological markers capable…
- Conditions
- Healthy, EEG, Transcranial Magnetic Stimulation
- Trial name
- NCT03537885
- Testing
- Transcranial Direct Current Stimulation, Transcranial Magnetic Stimulation, Electroencephalography (EEG)
- Where
- United States
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Burke Medical Research Institute
Bipolar Disorder
A Study to Evaluate the Effect of Single Doses of Drug A (Lamotrigine) and Drug B (Vofopitant) Alone and in Combination on Resting Motor Threshold in Healthy Subjects
The purpose of this study is to investigate the effect of drug A on its own and when it is given in combination with drug B on markers of brain activity. The study will 1.
- Trial name
- NCT00907985
- Testing
- Vofopitant, Lamotrigine
- Where
- Germany
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Major Depression
High-Frequency vs. Theta-Burst TMS for Depression
The goal of this clinical trial was to learn if two different types of repetitive transcranial magnetic stimulation (rTMS) could help treat depression and anxiety in adults with major depressive disorder.
- Trial name
- NCT07181226
- Testing
- High-frequency repetitive transcranial magnetic stimulation, Intermittent Theta Burst Stimulation
- Where
- Czechia
- Volunteers
- 108 people
- Sponsor
- Krajská zdravotní, a.s. - Nemocnice Most, o.z.
Chronic Pain, Post-traumatic Stress Disorder (PTSD)
Accelerated Neuromodulation for Concurrent Post-Traumatic Stress Disorder (PTSD) & Chronic Pain in Veterans
The ANCHOR study is testing a novel, non-invasive brain stimulation program designed specifically for Veterans experiencing concurrent post-traumatic stress disorder (PTSD) and chronic pain.
- Trial name
- ANCHOR (NCT07192536)
- Testing
- Transcranial magnetic stimulation
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- Legion Veterans Village Research Foundation
Parkinson's Disease
rTMS for the Treatment of Freezing of Gait in Parkinson's Disease
This study is a double blind comparative study examining the effectiveness of the rTMS treatment on Freezing of Gait (FOG) in patients with Parkinson's disease (PD).
- Trial name
- NCT03219892
- Testing
- High-frequency rTMS
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Xuanwu Hospital, Beijing
Blepharospasm
Brain Changes in Blepharospasm
This study will examine the role of certain areas of the brain in blepharospasm, a type of dystonia (abnormality of movement and muscle tone) that causes unwanted or uncontrollable blinking or closing of the eyelids.
- Trial name
- NCT00500799
- Where
- United States
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Schizophrenia
cTBS on First-episode Drug Naive Patients With Schizophrenia
cTBS is a promising novel intervention, which have strong potentials on moderating disease syndrome, suck as verbal hallucination, and cognitive deficits in schizophrenia, as it has been proved for the treatment of depression.
- Trial name
- NCT05086133
- Testing
- transcranial magnetic stimulation
- Where
- China
- Volunteers
- 44 people
- Sponsor
- Central South University
Mild Cognitive Impairment
Network-guided TMS in Early Alzheimer's Disease
The proposed research will test a novel network-based neurostimulation approach using MRI-derived measures of brain connectivity to establish target sites for neurostimulation and test for the enhancement of memory function…
- Trial name
- NetTMS (NCT04549155)
- Testing
- Transcranial Magnetic Stimulation
- Where
- United States
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Duke University
tDCS, Physical Activity + tDCS
Influence of Physical Exercise on Neuroplasticity and Sensorimotor Networks in Older Adults
The purpose of this study is to investigate the influence of a single session of moderate aerobic exercise on motor cortex neuroplasticity in older adults, both alone and in combination with transcranial direct current…
- Conditions
- tDCS, Physical Activity + tDCS, Physical Inactivity + tDCS
- Trial name
- EXOPLASTIC (NCT07438808)
- Testing
- Aerobic Exercise, Physical Inactivity, Transcranial Magnetic Stimulation
- Where
- France
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Universite du Littoral Cote d'Opale
Cortical Organisation of Vestibular Integration
Vestibular Cortex and TMS
In human, the cerebral cortex forms a network of vestibular cortical areas which functional role remains unknown. In patients with localised cortical lesions the investigator has previously demonstrated that the parieto-temporal…
- Trial name
- CoVest (NCT01779752)
- Where
- France
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- Institut National de la Santé Et de la Recherche Médicale, France
Methamphetamine-dependence
Paired Associative Stimulation in Methamphetamine Addiction
The investigators use paired associative stimulation (PAS) protocols to target cortico-cortical and cortico-subcortical networks to study cognitive deficits in methamphetamine addiction.
- Trial name
- NCT03910608
- Testing
- MagPro X100 device (MagVenture, Farum, Denmark)
- Where
- China
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Shanghai Mental Health Center
Tobacco Use Disorder, Repetitive Transcranial Magnetic Stimulation
fMRI Study of the Neural Mechanism of rTMS in the Treatment of Nicotine Dependence
The goal of this clinical trial is to investigate the efficacy of treatment and the efficacy-related neural network mechanisms by stimulating the left dorsolateral prefrontal lobe with rTMS to nicotine dependent.
- Trial name
- NCT06762535
- Testing
- repetitive transcranial magnetic stimulation
- Where
- China
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Tang-Du Hospital
Prader-Willi Syndrome
Cerebellar TMS and Satiety in Prader-Willi Syndrome
This study uses a noninvasive technique called transcranial magnetic stimulation (TMS) to study hyperphagia and satiety in Prader-Willi syndrome.
- Trial name
- NCT05938543
- Testing
- Repetitive Transcranial Magnetic Stimulation (rTMS)
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Brigham and Women's Hospital
Sleep Disturbance, Interaction
Integration of Tai Chi and Repetitive Transcranial Magnetic Stimulation for Sleep Disturbance in Older Adults
This is a novel and the first study to investigate the impacts of the integrated treatment of Tai Chi (TC) and repetitive transcranial magnetic stimulation (rTMS) on sleep disturbances and the potential mechanisms of arousal…
- Trial name
- NCT06411509
- Testing
- TC plus active rTMS, TC-alone, Low intensity physical exercise
- Where
- Hong Kong
- Volunteers
- 152 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Locked in Syndrome
TDCS-RTMS Intervention for Motor Function
This study was a multicenter randomized double-blind, sham controlled trial initiated by Zhujiang Hospital of Southern Medical University.
- Trial name
- TRIMLiS (NCT07257601)
- Testing
- Repetitive transcranial magnetic stimulation, Transcranial direct current stimulation
- Volunteers
- 72 people
- Sponsor
- Zhujiang Hospital
Fibromyalgia
Transcranial Magnetic Stimulation and Hyperbaric Chamber for Women Fibromyalgia
Fibromyalgia syndrome (FMS) is a multisystem disease, characterized by generalized chronic musculoskeletal pain. In addition, there is a lot of care for fatigue, sleep disorders, morning stiffness, cognitive disorders…
- Trial name
- NCT03801109
- Testing
- Hyperbaric group, Magnetic group, Physical group
- Where
- Spain
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- University of Valencia
Migraine, Healty Controls
Motor Evoked Potential and Cortical Silent Period in Migraine
The primary objective of this study is to assess the level of inhibitory control in the motor cortex of migraine patients using objective and non-invasive methods.
- Trial name
- NCT07250464
- Testing
- Transcranial Magnetic Stimulation (TMS), Surface Electromyography (sEMG), Needle EMG / Single Motor Unit (SMU) Recording
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Istanbul Gelisim University
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