Clinical trials: Transcranial Magnetic Stimulation
Major Depressive Disorder
Beat the Blues in Pregnancy Study - Transcranial Magnetic Stimulation
The purpose of this study is to determine if repetitive transcranial magnetic stimulation (TMS) will alleviate symptoms of major depressive disorder (MDD) in pregnant women.
- Trial name
- TMS (NCT01492309)
- Testing
- Active Transcranial Magnetic Simulation
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- University of Pennsylvania
Mood Disorder, Bipolar Disorder
A Pilot Study on Repetitive Transcranial Magnetic Stimulation (rTMS) Treatment of Bipolar Depression
This is a pilot project to study if repetitive Transcranial Magnetic Stimulation (rTMS) will benefit patients with bipolar depression safely.
- Conditions
- Mood Disorder, Bipolar Disorder, Major Depression, Depression
- Trial name
- TMS-BD (NCT00699218)
- Testing
- Magnetic Stimulator Rapid2 made by Magstim Company Ltd. U.K.
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- University of California, Davis
Psychomotor Retardation, Psychomotor Slowing
Transcranial Magnetic Stimulation (TMS) for Motor Symptoms in Psychiatric Disorders
Psychomotor slowing may occur in major psychiatric disorders, such as major depressive disorders or schizophrenia spectrum disorders. It refers to slowing of fine motor skills, motor planning and gross motor behavior.
- Conditions
- Psychomotor Retardation, Psychomotor Slowing, Schizophrenia and Related Disorders, Major Depressive Disorder
- Trial name
- NCT03275766
- Testing
- DLPFC facilitatory, SMA inhibitory, SMA facilitatory
- Where
- Switzerland
- Volunteers
- 45 people
- Sponsor
- University of Bern
Smoking, Cigarette, Craving
QuitFast: Evaluating Transcranial Magnetic Stimulation as a Tool to Reduce Smoking Directly Following a Quit Attempt
Cigarette smoking constitutes the greatest preventable cause of mortality and morbidity in the US. The most critical period for long term success of smoking cessation appears to be in the first 7 days after the quit date.
- Conditions
- Smoking, Cigarette, Craving, Addiction, Nicotine
- Trial name
- NCT03576768
- Testing
- Real cTBS, Real iTBS
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Medical University of South Carolina
Alcohol Use Disorder
Transcranial Magnetic Stimulation for the Treatment of Veterans With Alcohol Use Disorders
At least 60% of Veterans with an alcohol use disorder will relapse within 6 months of treatment, irrespective of the type of treatment they receive.
- Trial name
- NCT03191266
- Testing
- Active rTMS
- Where
- United States
- Volunteers
- 49 people
- Sponsor
- VA Office of Research and Development
Schizophrenia
rTMS as a Probe of Episodic Memory Neurocircuitry in Schizophrenia
This will be a single site pilot study. 30 subjects with Early Phase Psychosis (EPP), defined as medical record documentation of the onset of clinically significant psychotic symptoms within the past ten years, will be enrolled.
- Trial name
- rTMS-EM (NCT04182113)
- Testing
- 1 Hz rTMS Stimulation
- Where
- 2 sites in United States
- Volunteers
- 25 people
- Sponsor
- Indiana University
Stress Disorders, Post-Traumatic
EEG Personalized Transcranial Magnetic Stimulation (eTMS) for Post-Traumatic Stress Disorder
This is an open-label safety pilot study of the Electroencephalogram (EEG) Transcranial Magnetic Stimulation (eTMS) treatment for Post-Traumatic Stress Disorder (PTSD).
- Trial name
- NCT06081309
- Testing
- EEG-based personalized TMS
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Wave Neuroscience
Parkinson's
Cognitive Dysfunction In Parkinson's
We hypothesize that reductions in gamma activity are a key mechanism underlying cognitive dysfunction in PD and that interventions to increase gamma activity will improve cognition.
- Trial name
- KL2 (NCT02468804)
- Testing
- rTMS
- Where
- United States
- Volunteers
- 107 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Depression
Imaging Biomarkers for TMS Treatment of Depression
The purpose of this research is to learn more about how rTMS works to reduce the symptoms of depression. This information can be used to improve the effectiveness of the treatment.
- Trial name
- NCT01900314
- Testing
- repetitive Transcranial Magnetic Stimulation (rTMS)
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Michigan
Nicotine Dependence
Repetitive Transcranial Magnetic Stimulation (rTMS) for Nicotine Addiction
Cigarette smoking remains a significant public health concern. A magnetic field applied to the outside of the skull can produce electrical activity in the brain without significant pain or the need for anesthesia.
- Trial name
- rTMS (NCT02401672)
- Testing
- Transcranial magnetic stimulation
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
Major Depressive Disorder
Treatment of Depression With Connectivity Guided Robotically Delivered rTMS
The purpose of this study is to determine the clinical effects (if any) of connectivity-guided repetitive transcranial magnetic stimulation (rTMS) in the treatment of major depressive disorder (MDD) to provide clues about the…
- Trial name
- NCT02802293
- Testing
- repetitive transcranial magnetic stimulation, robotic arm
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- The University of Texas Health Science Center at San Antonio
Depression
iTBS for Adolescent Depression: An Open Label Study Evaluating Safety and Efficacy of Treatment
This is an open label, pilot, feasibility study evaluating effects of Intermittent Theta Burst Transcranial Magnetic Stimulation (iTBS) on 5 eligible adolescents for the treatment of depression.
- Trial name
- NCT04485455
- Testing
- iTBS Device/Motor Threshold Coil, iTBS Device/Treatment Coil
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- University of North Carolina, Chapel Hill
Epilepsies, Partial
Treatment of Difficult to Control Focal Epilepsy With Repetitive Transcranial Magnetic Stimulation (rTMS)
The investigators will treat patients with fully characterized refractory unifocal neocortical epilepsy with a technique that delivers magnetic waves (transcranial magnetic stimulation, TMS) to the region that causes the…
- Trial name
- NCT01745952
- Testing
- figure-of-eight active rTMS coil, round active rTMS coil
- Where
- Belgium
- Volunteers
- 11 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Traumatic Brain Injury
Amantadine + rTMS as a Neurotherapeutic for Disordered Consciousness
The purpose of this study is to examine the safety and efficacy of repetitive transcranial magnetic stimulation (rTMS) combined with Amantadine relative to rTMS Alone and Amantadine Alone for persons in chronic states of…
- Trial name
- NCT02025439
- Testing
- rTMS, Amantadine
- Where
- 2 sites in United States
- Volunteers
- 4 people
- Sponsor
- Edward Hines Jr. VA Hospital
Memory
Individualized Closed Loop TMS for Working Memory Enhancement
The study is investigating working memory brain states by using transcranial magnetic stimulation (TMS) in combination with functional magnetic resonance imaging (fMRI).
- Trial name
- NCT04402294
- Testing
- Functional Magnetic Resonance Imaging (fMRI), Repetitive Transcranial Magnetic Stimulation (rTMS)
- Where
- United States
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Traumatic Brain Injury
Effects of Huperzine A in Treatment of Moderate to Severe TBI
We will explore the use of Huperzine A in patients who have sustained a moderate to severe Traumatic Brain Injury. We aim to determine whether Huperzine A, as compared with placebo, would have an effect on memory function after…
- Trial name
- NCT01676311
- Testing
- Huperzine A
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- Spaulding Rehabilitation Hospital
Depression
Treatment, Emotion, and Neuromodulation of Depression (TREND) Study
The investigators will administer theta burst stimulation (TBS) in efforts to observe a decrease in severity of reported depression symptoms. A subset of participants will receive positive affect training during this intervention.
- Trial name
- TREND (NCT05436379)
- Testing
- Theta Burst Stimulation
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- Erika Forbes
Bipolar Disorder, Transcranial Magnetic Stimulation
Pilot Study of Neuromodulation for Enhancement of Emotion Regulation in Bipolar Mood Disorders
The investigators are conducting this research study to better understand how individuals with bipolar disorder regulate their emotions, and if the study can use a technique called "transcranial magnetic stimulation" or TMS to…
- Trial name
- NCT03622749
- Testing
- Transcranial Magnetic Stimulation (TMS)
- Where
- United States
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Parkinson's Disease
Effects of Combined rTMS and Treadmill Training in People With Parkinson's Disease
The purpose of this study is to investigate whether the beneficial effect of treadmill training on people with Parkinson's disease can be enhanced by high- and low-frequency repetitive transcranial magnetic stimulation (rTMS).
- Trial name
- NCT02701647
- Testing
- Repetitive transcranial magnetic stimulation (rTMS), Treadmill training
- Where
- Hong Kong
- Volunteers
- 51 people
- Sponsor
- The Hong Kong Polytechnic University
Primary Progressive Aphasia
HDtDCS in Logopenic Variant PPA: Effects on Language and Neural Mechanisms
This study aims to evaluate the effectiveness of a therapy called High-Definition Transcranial Direct Current Stimulation (HD-tDCS) for the treatment of the language deficits experienced by people with a type of Primary…
- Trial name
- NCT03805659
- Testing
- HD-tDCS
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Medical College of Wisconsin