Clinical trials: Transcranial Magnetic Stimulation
Depression, Depressive Disorder, Treatment-Resistant
Improving Brain Stimulation Through Imaging
There are two protocols, one involving rTMS therapy in people with treatment resistant depression and one involving tDCS in people with stress from the COVID 19 pandemic.
- Conditions
- Depression, Depressive Disorder, Treatment-Resistant, COVID Stress, PTSD - Post Traumatic Stress Disorder
- Trial name
- IBSI (NCT03851380)
- Testing
- Psychological / Functional Assessment, Structural and Functional MRI, Transcranial Magnetic Brain Stimulation and MR Image Guidance
- Where
- United States
- Volunteers
- 54 people
- Sponsor
- VA Office of Research and Development
Neuromodulation, Parkinsonian Syndromes
Individual Neuromodulation for PDS
Parkinsonian Syndromes (PDS) with predominant motor dysfunction include progressive supranuclear palsy (PSP), multiple system atrophy (MSA) and corticobasal degeneration (CBD).
- Conditions
- Neuromodulation, Parkinsonian Syndromes, Transcranial Magnetic Stimulation, Transcranial Direct Current Stimulation
- Trial name
- NCT06193278
- Testing
- Neuromodulation
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Ruijin Hospital
Primary Headache
Clinical Features and Current Treatment of Primary Headache
This study is a prospective, observational cohort study. The plan of this study is to consecutively enroll 2,000 primary headache patients who meet the inclusion criteria from the neurology outpatient department and inpatient…
- Trial name
- NCT06883955
- Testing
- Disease education, pharmacological treatment, Non-pharmacological treatment
- Where
- China
- Volunteers
- 2,000 people
- Sponsor
- Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Stroke
PCMS Task After Moderate-to-severe Stroke
Researchers at the University of Pittsburgh are conducting a research study to see how combining brain, nerve, and hand stimulation affect hand movement after stroke.
- Trial name
- NCT05736653
- Testing
- Task-specific PCMS, PCMS-rest
- Where
- United States
- Volunteers
- 51 people
- Sponsor
- University of Utah
Autism Spectrum Disorder
Role of GABAergic Transmission in Auditory Processing in Autism Spectrum Disorder
Background: Autism spectrum disorder (ASD) is a complex neurodevelopmental syndrome. Researchers think brain development may be controlled by gamma-aminobutyric acid (GABA).
- Trial name
- NCT04798274
- Testing
- Continuous Theta Burst Stimulation
- Where
- United States
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- National Institute of Mental Health (NIMH)
Fibromyalgia, Chronic Pain
Transcranial Magnetic Stimulation for Treating Women With Chronic Widespread Pain
While acute pain after surgery or trauma comes on suddenly and lasts for a limited amount of time, chronic pain persists and can continue for months and even years.
- Conditions
- Fibromyalgia, Chronic Pain, Depression
- Trial name
- NCT00524420
- Testing
- rTMS
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- University of Washington
Young Healthy Adults (no Medical Condition/Disease)
Creatine and Motor Skill Acquisition
The investigators will conduct a double-blind, placebo-controlled, repeated measures study of the effects of oral creatine monohydrate supplementation on motor skill acquisition and neurophysiology in young healthy adults.
- Trial name
- NCT05201651
- Testing
- Creatine Monohydrate
- Where
- Canada
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- University of Regina
Spinal Cord Injury Cervical, Neuropathic Pain
PAS for Post-SCI Neuropathic Pain
The investigators have shown in incomplete SCI patients that long-term paired associative stimulation is capable of restoring voluntary control over some paralyzed muscles and enhancing motor output in the weak muscles.
- Trial name
- NCT05362422
- Testing
- long-term paired associative stimulation
- Where
- Finland
- Volunteers
- 5 people
- Sponsor
- Helsinki University Central Hospital
Shoulder Impingement Syndrome, Transcranial Magnetic Stimulation
The Effects of Exercise Training on Corticospinal System in Overhead Athletes With Shoulder Impingement Syndrome
Shoulder impingement syndrome is the most common shoulder disorder in overhead athletes. It describes a mechanical compression of subacromial bursa and rotator cuff tendons during arm movement, which results in pain and injuries.
- Conditions
- Shoulder Impingement Syndrome, Transcranial Magnetic Stimulation, Central Nervous System, Biomechanical Phenomena
- Trial name
- NCT04014491
- Testing
- Scapula control exercise, scapular strengthening exercise, No intervention
- Where
- Taiwan
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- National Yang Ming Chiao Tung University
Focal Dystonia
Neurophysiology of Task-Specificity of Focal Hand Dystonia
This study will examine how the brain coordinates movement in patients with focal hand dystonia. Patients with dystonia have muscle spasms that cause uncontrolled twisting and repetitive movement or abnormal postures.
- Trial name
- NCT00309010
- Where
- United States
- Volunteers
- 115 people, healthy volunteers welcome
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Major Depressive Disorder
Spectral TMS (s-TMS)
This study will analyze the feasibility, safety, and tolerability of administering repetitive Transcranial magnetic stimulation(TMS) at frequencies other than standard 10 Hz.
- Trial name
- STMS (NCT04040062)
- Testing
- Transcranial Magnetic Stimulation
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- University of California, Los Angeles
Parkinson Disease
Comparison of Different Non-invasive Electrical Stimulation Protocols to Facilitate Rehabilitation in Parkinson's Disease Subjects With Postural Instability and Gait Disorders
The trial will include 51 adult participants with Parkinson's disease and postural instability and gait disorders (PD-PIGD) and 20 age- and sex-matched healthy controls.
- Trial name
- NCT06868160
- Testing
- Rehabilitation, tDCS, tsDCS (first cycle)
- Where
- Italy
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- IRCCS San Raffaele
Major Depressive Disorder, Major Depressive Episode
SAINT for MDD in an Inpatient Setting Follow-on
Randomized, multi-site, sham-controlled, double-blinded study
- Conditions
- Major Depressive Disorder, Major Depressive Episode, Suicidal Ideation
- Trial name
- NCT06462820
- Testing
- Active SAINT Stimulation
- Where
- 4 sites in United States
- Volunteers
- 2 people
- Sponsor
- Magnus Medical
Neurologic Disorder, Healthy
Establishment of Delphi-MD Safety Performance and Reliability
A retrospective analysis of collected datasets. In this study we aim to establish Delphi-MD's safety and performance reliability for assessment and monitoring of Transcranial Magnetic Stimulation (TMS) Evoked Potentials (TEPs) as…
- Trial name
- NCT06368024
- Testing
- This is a retrospective analysis study of data collected with a diagnostic medical device
- Where
- Israel
- Volunteers
- 263 people, healthy volunteers welcome
- Sponsor
- QuantalX Neuroscience
Transcranial Magnetic Stimulation, Non-suicidal Self-injury
Stanford Neuromodulation Therapy (SNT) for Non-suicidal Self-injury (NSSI)
To investigate the treatment effect of Stanford Neuromodulation Therapy (SNT) on patients with Non-suicidal Self-injury (NSSI) and the underlying neural mechanism.
- Trial name
- NCT06139484
- Testing
- Transcranial Magnetic Stimulation
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Anhui Medical University
Major Depressive Disorder
Randomized Controlled Trial of Conventional vs Theta Burst rTMS
This trial will compare a novel form of rTMS, intermittent Theta Burst Stimulation to the standard conventional high frequency left sided stimulation protocol.
- Trial name
- HFL vs TBS (NCT01887782)
- Testing
- HFL rTMS, iTBS
- Where
- 3 sites in Canada
- Volunteers
- 414 people
- Sponsor
- Centre for Addiction and Mental Health
Rhythmic Transcranial Magnetic Stimulation (rTMS) Effect on Hierarchical Cognitive Control
Causal Role of Delta and Theta Oscillations in Hierarchical Cognitive Control
The purpose of this clinical trial is to evaluate the effect of rhythmic transcranial magnetic stimulation (TMS) delivered at delta (2.2 Hz) or theta (6.5 Hz) frequency on cognitive control.
- Trial name
- NCT06734377
- Testing
- Delta TMS, Theta TMS, Arrhythmic TMS
- Where
- United States
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Florida State University
Depressive Disorder, Treatment-Resistant
rTMS With and Without iCBT For the Treatment of Resistant Depression (TRD)
This is a prospective, two-arm randomized controlled trial. 100 patients diagnosed with resistant depression in psychiatric care clinic in Edmonton, Alberta, Canada will be randomized to one of two conditions: (1) enrolment in…
- Trial name
- NCT04239651
- Testing
- Repetitive Transcranial Magnetic Stimulation (rTMS), Internet-Delivered Cognitive Behavior Therapy (iCBT)
- Where
- Canada
- Volunteers
- 80 people
- Sponsor
- University of Alberta
Sleep Wake Disorders, Lung Neoplasms
Low-Frequency rTMS for Sleep After Thoracoscopic Lung Resection
This single-center randomized, double-blind, sham-controlled trial will evaluate whether low-frequency repetitive transcranial magnetic stimulation (rTMS) improves postoperative inpatient sleep in adults undergoing elective…
- Trial name
- TMS-SLEEP-VATS (NCT07796451)
- Testing
- Active Low-Frequency Repetitive Transcranial Magnetic Stimulation
- Volunteers
- 220 people
- Sponsor
- The First Affiliated Hospital of Guangzhou Medical University
Cerebral Palsy, Spastic, Transcranial Magnetic Stimulation, Repetitive
Priming Effects of Ultra-high Frequency Quattro Pulse Transcranial Brain Stimulation Prior to Hand Motor Function Training in Children With Unilateral Spastic Cerebral Palsy
Unilateral spastic cerebral palsy (USCP) leads to life-long impairment with a hemiparesis of the affected side of the body. Rehabilitation efforts combine evidence based methods such as constrained induced movement therapy (CIMT)…
- Trial name
- TRAINCP (NCT05165472)
- Testing
- Quadri-pulse theta burst stimulation
- Where
- 2 sites in Germany
- Volunteers
- 32 people
- Sponsor
- Technical University of Munich
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