Clinical trials: Transcranial Magnetic Stimulation
Autism Spectrum Disorder, High-functioning Autism
Effects of Transcranial Pulse Stimulation on ASD
The aim of this study is to evaluate the efficacy and tolerability of TPS on young adolescents with ASD. Methods: This is a two-armed, randomized, double-blinded, sham-controlled trial.
- Trial name
- NCT05408793
- Testing
- Transcranial Pulse Stimulation
- Where
- Hong Kong
- Volunteers
- 32 people
- Sponsor
- The Hong Kong Polytechnic University
Alzheimer Disease, Mild Cognitive Impairment
Enhancing Memory in Mild Cognitive Impairment and Early Stage Alzheimer's Disease
The investigators have developed a low-risk transcranial Electrical Stimulation (tES) treatment that has improved learning and performance in young adults up to nearly 4 times when compared with a sham control.
- Trial name
- MEMORI (NCT05077826)
- Testing
- North Coast Medical Activadose II
- Where
- United States
- Volunteers
- 98 people, healthy volunteers welcome
- Sponsor
- The Mind Research Network
Neuropsychiatric Disorders
Reference Measurements of the Neuronal Integration Window and Anatomical and Functional MRI (Magnetic Resonance Imaging)
Our studies on MRI (Magnetic resonance imaging) biomarkers in neuropsychiatric disorders rely on reference data from control subjects which are dependent from our scanner.
- Trial name
- FIT-IRM (NCT07453108)
- Testing
- MRI (Magnetic Resonance Imaging), TMS (Transcranial Magnetic Stimulation)
- Where
- France
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University Hospital, Strasbourg, France
Schizophrenia
Repetitive Transcranial Magnetic Stimulation (rTMS) for the Treatment of Negative Symptoms in Schizophrenia
Schizophrenia is a major psychotic disorder that presents an enormous burden to the patients and their relatives. Despite treatment with second generation antipsychotics, negative symptoms and cognitive impairment often persist…
- Trial name
- RESIS (NCT00783120)
- Testing
- Repetitive transcranial magnetic stimulation
- Where
- 3 sites in Germany
- Volunteers
- 197 people
- Sponsor
- Institut fuer anwendungsorientierte Forschung und klinische Studien GmbH
Major Depressive Disorder (MDD)
Electrophysiological Biomarkers in Accelerated TMS for Depression
This study investigates whether physiological signals recorded during transcranial magnetic stimulation (TMS) can predict which patients with major depression respond to treatment.
- Trial name
- NCT07615387
- Testing
- Accelerated bilateral dmPFC-iTBS
- Where
- Turkey (Türkiye)
- Volunteers
- 32 people
- Sponsor
- Istanbul University - Cerrahpasa
Stroke, Acute Ischemic
Low-Frequency REpetitive TRanscranial Magnetic Stimulation Combined With Endovascular Treatment in ACute Ischemic StrokE
This is a multicenter, randomized, double-blind, sham-controlled, investigator-initiated clinical study, to evaluate the clinical efficacy and safety of LF-rTMS in rescuing the ischemic penumbra, reducing disability rate and…
- Trial name
- RETRACE-II (NCT06064747)
- Testing
- LF-rTMS
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Beijing Tiantan Hospital
Depression / Major Depressive Disorder
Longitudinal Effects of Brain Stimulation on Decision-Making and Reward Learning
This study investigates the longitudinal effects of brain stimulation treatments on decision-making and reward learning. Here, daily assessments of reinforcement learning behavior are used in patients with depression who receive…
- Trial name
- NCT07823218
- Where
- Germany
- Volunteers
- 100 people
- Sponsor
- University of Bonn
West Syndrome
Cortical Excitability in West Syndrome Using Transcranial Magnetic Stimulation
Currently, no literature is available regarding degree of cortical excitability and its correlation with various epileptic syndromes and disorders such as West Syndrome in pediatric age group.
- Trial name
- NCT06201897
- Testing
- ACTH/Oral Steroids
- Where
- India
- Volunteers
- 40 people
- Sponsor
- All India Institute of Medical Sciences
Nicotine Use Disorder
Identify the Optimal TMS Pulse Protocol to Modulate Reward Activity
The primary goal will be to identify the optimal pulse protocol by systematically measuring the efficacy of various theta burst stimulation and repetitive rTMS protocols to increase and decrease the reward positivity in dependent…
- Trial name
- NCT06695884
- Testing
- Transcranial Magnetic Stimulation
- Where
- United States
- Volunteers
- 42 people
- Sponsor
- Rutgers, The State University of New Jersey
Tobacco Use Disorder, Psychiatric Disorder
Transcranial Magnetic Stimulation for Nicotine Dependence: An Effectiveness-Implementation Trial
Tobacco smoking is the leading preventable cause of morbidity and mortality worldwide. However, currently available treatments, including standard pharmacotherapy and behavioural support, are limited in their efficacy…
- Conditions
- Tobacco Use Disorder, Psychiatric Disorder, Nicotine Dependence
- Trial name
- NCT06534047
- Testing
- Brainsway H4 deep Repetitive Transcranial Magnetic Stimulation (rTMS) coil, Nicotine replacement
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- Centre for Addiction and Mental Health
Spinal Cord Injuries and Disorders (SCI/D)
Using Non-invasive Brain and Spinal Cord Stimulation to Improve Arm and Hand Function After Spinal Cord Injury
Cervical spinal cord injury (SCI) disrupts communication between the brain and spinal circuits, affecting voluntary movement control and contributing to arm and hand impairments, the top recovery priority for people with…
- Trial name
- NCT07423949
- Testing
- Cerebellar theta burst stimulation, Cervical transcutaneous spinal cord stimulation, Functional task practice
- Where
- Canada
- Volunteers
- 24 people
- Sponsor
- University of British Columbia
Spinal Cord Injuries
Pharmacological Agents for Chronic Spinal Cord Injury (SCI)
The purpose of this study is to investigate the short-term effects of 3 approved FDA drugs (cyproheptadine (CPH), carbidopa-levodopa (CD-LD), and atomoxetine (ATX)) on motor responses when delivered in combination with hand…
- Trial name
- NCT05708274
- Testing
- CPH + hand training, CD-LD + hand training, ATX + hand training
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Bronx VA Medical Center
Cerebrovascular Disease
Comparing Effects of Various Combinations of 6 Hertz(Hz) rTMS & LFrTMS on Motor Recovery Due to Cerebrovascular Disease
To compare the effects of various combinations between 6 hertz(Hz) rTMS \& LFrTMS on the limb motor dysfunction due to cerebral vascular disease.
- Trial name
- NCT03012204
- Testing
- real LFrTMS at unaffected M1, real primed LFrTMS at unaffected M1, combined rTMS at both M1
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Beijing Hospital
Stroke
Efficacy of Personalized Repetitive Transcranial Magnetic Stimulation Protocol Based on Functional Reserve to Enhance Upper Limb Function in Subacute Stroke Patients
The objective of this study was to determine the effects of protocols of repetitive transcranial magnetic stimulation (rTMS) therapy based on the functional reserve of each hemiplegic stroke patient in subacute phase, compared to…
- Trial name
- NCT06270238
- Testing
- High-Frequency1, cTBS1, High-Frequency2
- Where
- South Korea
- Volunteers
- 120 people
- Sponsor
- Samsung Medical Center
Schizophrenia and Related Disorders
rTMS for Depressive, Positive and Negative Symptoms, and Physiological Indices of Schizophrenia Patients
Around 40% of schizophrenia patients present depressive symptoms, which are associated with elevated suicide and violence risk and poor prognosis and quality of life.
- Trial name
- NCT05671185
- Testing
- Repetitive Transcranial Magnetic Stimulation
- Where
- Taiwan
- Volunteers
- 180 people
- Sponsor
- National Taiwan University Hospital
Major Depressive Disorder
A Randomised Double-Blind Trial of Targeted Repetitive Transcranial Magnetic Stimulation in Major Depressive Disorder
The study will involve a 3-week (15 session) randomized double-blind clinical trial of two repetitive transcranial magnetic stimulation (rTMS) conditions in patients with treatment resistant depression.
- Trial name
- NCT00168376
- Testing
- Transcranial Magnetic Stimulation
- Where
- Australia
- Volunteers
- 60 people
- Sponsor
- The Alfred
Traumatic Brain Injury
rTMS to Improve Cognitive Function in TBI
This project will study 40 Veterans identified with symptoms understood to characterize mild to moderate Traumatic Brain Injury (TBI) including Post Traumatic Stress Disorder (PTSD).
- Trial name
- rTMSTBI (NCT02152540)
- Testing
- rTMS
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- VA Office of Research and Development
Schizophrenia, Transcranial Magnetic Stimulation
Personalized iTBS in Real-World Clinical Settings for Schizophrenia
This study is designed to determine whether neuronavigation-guided, personalized Intermittent Theta-Burst Stimulation (iTBS) can produce clinically benefits for patients with schizophrenia when delivered in real-world treatment…
- Trial name
- EPSREAL-SC (NCT07176468)
- Testing
- Neuronavigation-guided individualized iTBS
- Where
- 2 sites in China
- Volunteers
- 40 people
- Sponsor
- Anhui Medical University
Stroke
Structurally Reorganizing Motor Cortex in Stroke Patients Through Hebbian-type Stimulation
Stroke is a leading cause of morbidity in the United States but identification of treatment strategies to improve outcome is limited by the incomplete understanding of the mechanisms of recovery.
- Trial name
- NCT01569607
- Testing
- Repetitive Transcranial Magnetic Stimulation (rTMS)
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- Cathrin Buetefisch
Wilson Disease, Movement Disorders
Inhibitory rTMS in Dystonic Wilson Patients
Wilson disease is a genetic disorder resulting in copper accumulation in liver, brain and eye. The neurologic complications include dystonic syndrome, which is a prolonged and excessive muscle activation responsible for abnormal…
- Conditions
- Wilson Disease, Movement Disorders, Repetitive Transcranial Magnetic Stimulation
- Trial name
- WILSTIM (NCT01980433)
- Testing
- Repetitive Transcranial Magnetic Stimulation (rTMS), pre and post-rTMS electroencephalogram, WCRS
- Where
- France
- Volunteers
- 14 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
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