Clinical trials: Treatment as usual
Ischemic Stroke, Transient Ischemic Attack
StAtins in Frail OldEr Patients with Ischemic Stroke or Transient Ischemic Attack - the Randomized Controlled Trial
Two Dutch guidelines (Stroke and Cardiovascular Risk Management) provide conflicting advice on optimal statin treatment in older patients.
- Trial name
- SAFEST - RCT (NCT06785727)
- Testing
- Statin (atorvastatin, fluvastatin, pravastatin, rosuvastatin or simvastatin)
- Volunteers
- 612 people
- Sponsor
- Prof. dr. Nathalie van der Velde
Risk Reduction, Urological Cancer
STRONG for Surgery & Strong for Life - Against All Odds: Intensive Prehabilitation for Risk Reduction in Cancer Surgery
Despite knowledge about the effect of preventive measures in lifestyle, smoking,nutrition, alcohol and physical activity (SNAP), there is a lack of systematic assessment of the overall lifestyle of the patient before surgery and…
- Conditions
- Risk Reduction, Urological Cancer, Surgery, Life Style
- Trial name
- STRONG-CS (NCT04088968)
- Testing
- Prehabilitation
- Where
- Denmark
- Volunteers
- 100 people
- Sponsor
- Bispebjerg Hospital
Posttraumatic Stress Disorder, Substance Abuse
Multicomponent Cognitive Behavioral Therapy(CBT) for Posttraumatic Stress Disorder (PTSD) and Substance Abuse
Purpose: To conduct a pilot study of a cognitive-behavioral treatment (CBT) for PTSD and substance abuse among persons with serious mental illness (SMI) treated in a community setting.
- Trial name
- PTSD/SUD (NCT01029197)
- Testing
- CBT and exposure therapy for PTSD, Treatment as Usual
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- University of North Carolina, Chapel Hill
Head and Neck Cancer
Adherence to Swallowing Exercises in Head and Neck Cancer
The goal of this research study is to help patients complete the swallowing and dental care exercises they are supposed to perform during radiation treatment.
- Trial name
- NCT00761397
- Testing
- Interview, Phone Call, Brochure
- Where
- United States
- Volunteers
- 485 people
- Sponsor
- M.D. Anderson Cancer Center
Smoking
Smoking Cessation E-Visit
The goal of this study is to develop, refine, and complete preliminary feasibility testing of a smoking cessation electronic visit (e-visit) for implementation in primary care/family medicine.
- Trial name
- NCT04316260
- Testing
- Smoking cessation e-visit, Treatment As Usual
- Where
- United States
- Volunteers
- 51 people
- Sponsor
- Medical University of South Carolina
Parkinson's Disease, Hyperprolactinemia
Study On Utilization Of Cabergoline For Compliance With Risk Minimization Activities (SUCRE)
The overall goal of this study will be to assess and monitor the adherence to and effectiveness of the new prescribing guidelines for cabergoline. Specific objectives will be to assess: 1.
- Trial name
- SUCRE (NCT01270711)
- Testing
- Study Drug
- Volunteers
- 22,014 people
- Sponsor
- Pfizer
Relatives
"Family Connections": a Program for Relatives of People With Borderline Personality Disorder
The aim of this study is to validate an intervention for relatives of people with borderline personality disorder in Spanish population in a randomized control trial.
- Trial name
- NCT04160871
- Testing
- Family Connections, Treatment As Usual
- Where
- Spain
- Volunteers
- 124 people, healthy volunteers welcome
- Sponsor
- Universitat Jaume I
Recidivism
Mixed Method Evaulation of Jockey Club Project ReBond
Overall, the investigators hypothesize that participants assigned to the intervention group (Project ReBond) will demonstrate significantly greater improvements across all outcomes compared to the control group.
- Trial name
- ReBond (NCT07593534)
- Testing
- Desistance-based Social Work, Treatment as Usual (TAU)
- Where
- Hong Kong
- Volunteers
- 300 people
- Sponsor
- The University of Hong Kong
Hematologic Malignancy
Reiki as a Complementary Therapy: A Pilot Study
This research is being done to test whether a complementary intervention, Reiki therapy, can provide added benefits to the standard patient care.
- Trial name
- NCT02207764
- Testing
- Reiki
- Where
- United States
- Sponsor
- Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Chronic Major Depression
Mindfulness-based Cognitive Therapy for Chronic Depression
The propose of the study is to investigate the efficacy of Mindfulness-based Cognitive Therapy (MBCT, Segal, Williams, \& Teasdale, 2002) for patients suffering from Chronic Major Depression.
- Trial name
- NCT01065311
- Testing
- Mindfulness-based Cognitive Therapy, The Cognitive Behavioral Analysis System of Psychotherapy, Standard psychiatric care
- Where
- Germany
- Volunteers
- 106 people
- Sponsor
- Johannes Michalak
Major Depressive Disorder, Generalized Anxiety Disorder
The Modular Protocol for Mental Health (MPMH)
Currently, our best psychological treatments for anxiety and mood disorders only focus on individual diagnoses. So, there are separate treatments for Panic Disorder, or Depressive Disorder, or Social Anxiety, etc.
- Conditions
- Major Depressive Disorder, Generalized Anxiety Disorder, Posttraumatic Stress Disorder, Social Anxiety Disorder
- Trial name
- MPMH (NCT03143634)
- Testing
- The Modular Protocol for Mental Health, Treatment-as-usual
- Where
- United Kingdom
- Volunteers
- 43 people
- Sponsor
- Medical Research Council Cognition and Brain Sciences Unit
Psychiatric Hospitalization, Mental Disorders
Character Strengths Intervention Among Psychiatrically Hospitalized Youth
Research has shown that identifying and using one's character strengths in new ways decreases depressive symptoms and increases happiness in adults in the general population.
- Conditions
- Psychiatric Hospitalization, Mental Disorders, Child/Adolescent Problems
- Trial name
- NCT02674932
- Testing
- Identifying and Using Signature Strengths, Identifying and Writing Down Coping Skills, Treatment as Usual
- Volunteers
- 153 people
- Sponsor
- University of Michigan
Breast Cancer
Developing a Comprehensive Exercise Service for Breast Cancer Process
"Moving Together" (Juntas en Movimiento) is a hospital-based, comprehensive, and personalized exercise service designed for women diagnosed with breast cancer.
- Trial name
- NCT07380971
- Testing
- Supervised in-person exercise training, Supervised Online Exercise Training, Home-Based Autonomous Exercise Program
- Where
- Spain
- Volunteers
- 200 people
- Sponsor
- GO fit Lab- Ingesport
Spinal Cord Injury
The Effect of a Combined Aerobic and Resistance Exercise (CARE) Training Programme on Cardiometabolic Outcomes in Individuals With Chronic Spinal Cord Injury: A Randomised Controlled Trial
The goal of this study is to investigate the effectiveness of an 8-week dietary energy restriction with exercise or dietary energy restriction alone on the cardiometabolic health outcomes of individuals with chronic spinal cord…
- Trial name
- CARE training (NCT06296771)
- Testing
- Dietary energy restriction group (D), Dietary energy restriction and exercise group (D+E)
- Where
- United Kingdom
- Volunteers
- 21 people
- Sponsor
- University of Bath
Multiple Sclerosis
Performance Evaluation of a 3D PSIR Sequence in MRI at 1.5T
Inclusion visit (D0): verification of inclusion and non-inclusion criteria information and collection of consent standard imaging protocol prescribed as part of the usual treatment: sagittal T1 and T2 slices after injection of…
- Trial name
- ESPOIR1-5 (NCT04707144)
- Testing
- MRI 1.5 tesla
- Where
- 6 sites in France
- Volunteers
- 106 people
- Sponsor
- Fondation Ophtalmologique Adolphe de Rothschild
Pain, Chronic, Knee Pain Chronic
Pain Reprocessing Therapy in Post-Operative Knee Pain
The goal of this clinical trial is to learn whether Pain Reprocessing Therapy (PRT) can help adults with knee pain after knee replacement surgery.
- Trial name
- REJOICE (NCT06800209)
- Testing
- Pain reprocessing therapy (PRT), Usual care
- Where
- 2 sites in United States
- Volunteers
- 110 people
- Sponsor
- Weill Medical College of Cornell University
Diabetes Mellitus, Diabetic Foot Ulcer
Relaxation Intervention in Patients With Diabetic Foot Ulcer
Diabetic foot ulcers (DFU) are one of the most serious complications of diabetes and can lead to amputations in 85% of cases, resulting in physical, psychological, family, social and economic consequences.
- Trial name
- NCT04652999
- Testing
- Muscle Relaxation with Guided Imagery, Neutral Guided Imagery
- Where
- 2 sites in Portugal
- Volunteers
- 54 people
- Sponsor
- University of Minho
Pulmonary Disease, Chronic Obstructive
Pilot Study: Post-Recovery LibEration From Oxygen in Exacerbated COPD
The investigators want to decrease inappropriate oxygen use for patients with COPD. The investigators are testing a new program that will stop oxygen prescriptions for patients that no longer need it and will instead provide them…
- Trial name
- RELIEF Pilot (NCT04854967)
- Testing
- Rescind home oxygen order, Provider Education, Patient Education
- Where
- United States
- Sponsor
- VA Office of Research and Development
Acute Leukemia
Benefits of Formalized Care Support Program Following Acute Leukemia Diagnosis
The purpose of this study is to determine the impact on anxiety between patients with a period of care support following their announcement of an acute leukemia (AL) diagnosis and patients without this accompaniment.
- Trial name
- ANX-LA (NCT07499765)
- Testing
- care support program after diagnosis announcement
- Where
- France
- Volunteers
- 110 people
- Sponsor
- Centre Henri Becquerel
Hot Flashes, Prostate Cancer
Acupuncture Versus Sham Acupuncture or Usual Care for Antiandrogen-Induced Hot fLashes in Prostate Cancer (AVAIL)
Hot flashes are a common and debilitating symptom among prostate cancer patients undergoing androgen deprivation therapy (ADT). Strong evidence from multiple rigorously designed studies indicated that venlafaxine provides partial…
- Conditions
- Hot Flashes, Prostate Cancer, Acupuncture
- Trial name
- AVAIL (NCT05069467)
- Testing
- Acupuncture
- Where
- 3 sites in China
- Volunteers
- 120 people
- Sponsor
- Guang'anmen Hospital of China Academy of Chinese Medical Sciences
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