Clinical trials: Vitamin C
Infections, Respiratory Tract
An Efficacy and Safety Study of Theraflu Night Powder as Oral Solution for Cold and Flu
The purpose of the study is to assess the short term efficacy of the Theraflu Night powder for oral solution in the Russian population in "Short term relief of the symptoms of colds, chills and influenza, including mild to…
- Trial name
- NCT02730364
- Testing
- Paracetamol, phenylephrine HCl, pheniramine maleate, and vitamin C
- Sponsor
- GlaxoSmithKline
Shock, Septic
Vitamin C, Hydrocortisone and Thiamine for Septic Shock
Prior data has shown that both corticosteroids and vitamin C reduce the activation of nuclear factor ƘB (NFƘB), thereby ultimately attenuating the systemic inflammatory response to sepsis/septic shock and augmenting the…
- Trial name
- CORVICTES (NCT03592693)
- Testing
- Combined Vitamin C and Stress-Dose Hydrocortisone
- Where
- 2 sites in Greece
- Volunteers
- 24 people
- Sponsor
- University of Athens
Healthy
Neural Mechanism of Cortisol Awakening Response Suppression Effect on Human High-order and Social Cognitions
CAR is short for cortisol awakening response. The neural mechanism of CAR effect on high-order cognition and social cognition is less known...
- Trial name
- NMCARSEHHSC (NCT02799134)
- Testing
- Dexamethasone, Vitamin C
- Where
- China
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- qinshaozheng
Anemia of Chronic Kidney Disease
Oral Liposomal Iron Versus Injectable Iron Sucrose for Anemia Treatment in Non-Dialysis Chronic Kidney Disease Patients
This study aims to assess the comparative effects of intravenous and liposomal oral iron on hemoglobin levels in non-dialysis CKD patients.
- Trial name
- NCT06556134
- Testing
- Intravenous Iron Sucrose, Oral Iron
- Where
- Morocco
- Volunteers
- 27 people
- Sponsor
- Centre Hospitalier Hassan II - Fès
Myelodysplastic Syndromes
Nivolumab With Chemotherapy in Refractory MDS
There is evidence of involvement of checkpoint pathways, including PD-1, in the pathogenesis and resistance of myelodysplastic syndrome (MDS).
- Trial name
- NCT03259516
- Testing
- Nivolumab, Azacitidine, Fludarabine
- Where
- Russia
- Volunteers
- 2 people
- Sponsor
- St. Petersburg State Pavlov Medical University
Myeloma
Velcade, Trisenox, Vitamin C and Melphalan for Myeloma Patients
Primary Objectives: 1. To evaluate the toxicity and safety of a combination of bortezomib with arsenic trioxide, ascorbic acid and high-dose melphalan in patients with multiple myeloma 2.
- Trial name
- NCT00469209
- Testing
- Trisenox (Arsenic Trioxide), Velcade (Bortezomib), Melphalan
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- M.D. Anderson Cancer Center
Macular Degeneration, Cataract
Age-Related Eye Disease Study (AREDS)
To assess the clinical course, prognosis, and risk factors of age-related macular degeneration (AMD) and cataract. To evaluate, in randomized clinical trials, the effects of pharmacologic doses of (1) antioxidants and zinc on the…
- Conditions
- Macular Degeneration, Cataract, Lens Opacities
- Trial name
- NCT00000145
- Testing
- Antioxidants, Zinc, Antioxidants and zinc
- Volunteers
- 4,757 people
- Sponsor
- National Eye Institute (NEI)
Colonoscopy
Polyethylene Glycol Versus Low Volume Solutions Prior to Colonoscopy
Study evaluates the efficacy and tolerability of low volume preparations compared with conventional 4L polyethylene glycol prior to colonoscopy
- Trial name
- NCT02956057
- Testing
- Polyethylene Glycols, Natrium picosulfate / Magnesium citrate, Polyethylene glycol / Ascorbic acid
- Where
- Czechia
- Volunteers
- 1,044 people
- Sponsor
- Tomas Bata Hospital, Czech Republic
Pancreatitis, Chronic
Prospective Study of Efficacy of Intra-muscular Vitamin D3 in Tropical Calcific Pancreatitis
The purpose of this study is to determine the efficacy of 2 different doses of intramuscular (IM) vitamin D3 as compared to an oral replacement dose in normalizing vitamin D levels in the blood of patients with tropical calcific…
- Trial name
- NCT00956839
- Testing
- Vitamin D3 (Cholecalciferol)
- Where
- India
- Volunteers
- 40 people
- Sponsor
- Sanjay Gandhi Postgraduate Institute of Medical Sciences
Anemia
Feasibility and Effectiveness of Distributing Micronutrient Sprinkles to Reduce Prevalence of Anemia
The objective of this study is to test the feasibility and effectiveness of distributing micronutrient sprinkles to 6-20 month old children participating in an integrated maternal and child health and nutrition program in rural…
- Trial name
- NCT00210405
- Testing
- "Sprinkles" containing mulitple micronutrients, Education/communication on use of micronutrient sprinkles, Fortified food aid (corn-soy blend)
- Where
- Haiti
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- International Food Policy Research Institute
Latent Autoimmune Diabetes in Adults (LADA)
Effects of Cofrogliptin on Beta-Cell Function in LADA Patients
This single-center, randomized, open-label, controlled study aims to evaluate the effect of cofrogliptin on pancreatic β-cell function in adults with latent autoimmune diabetes in adults (LADA).
- Trial name
- NCT07460336
- Testing
- Cofrogliptin, Vitamin D3, Metformin
- Where
- China
- Volunteers
- 84 people
- Sponsor
- Second Xiangya Hospital of Central South University
Abdominal Hysterectomy
Intravenous Ascorbic Acid Administration in Hysterectomy
vitamin C or ascorbic acid has known role in tissue repair. due to it's properties(water_soluble), vitamin c is not stored in the body and when depleted, the bleeding tendency will increase due to dysfunctional connective tissues…
- Trial name
- NCT03965637
- Testing
- vitamin C
- Where
- Iran
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Shahid Beheshti University
Thyroid Eye Disease
The Effect of a New Antioxidant Combination (ASTED) on Mild Thyroid Eye Disease (TED)
This randomized clinical trial is designed to evaluate the effect of selected antioxidant vitamins and minerals supplement named as ASTED: 1. β- Carotene (30 mg) 2. Vit C (100 mg) 3. Vit E (Alpha-Tocopherol Acetate): 60-200 IU 4.
- Trial name
- NCT02393183
- Testing
- ASTED, Selenium
- Where
- Iran
- Sponsor
- Iran University of Medical Sciences
Colonoscopy
MOVIPREP® Versus PICOLAX® Pilot Study
This will be a randomised, single-centre, single-blind, parallel-group, pilot study in patients undergoing colonoscopy. The primary objective is to evaluate the efficacy of MOVIPREP® versus PICOLAX® for gut cleansing prior to…
- Trial name
- NCT00312481
- Testing
- macrogol3350 NA sulphate NACL KCL ascorbic acid NA ascorbate, NA picosulfate magnesium citrate
- Where
- United Kingdom
- Volunteers
- 65 people
- Sponsor
- Norgine
Gestational Diabetes
MTHFR Mutation and Concentration of B12,Folic Acid,Homocysteine and HS CRP in the Blood of Pregnant Women With GDM.
Research hypothesis: pregnant women with gestational diabetes have elevated serum CRP values and homocysteine compared to pregnant women with normal glucose metabolism Elevated CRP and homocysteine values are associated with…
- Trial name
- NCT04952324
- Testing
- Blood sampling and determination of MTHFR mutation,vitamin B12, folic acid, homocystein and HS CRP
- Where
- 2 sites in Bosnia and Herzegovina
- Volunteers
- 100 people
- Sponsor
- University of Mostar
Colorectal Cancer
Pharmacodynamic Evaluation of Stool Output Following Oral Administration of Various Low Volume PEG3350-based Gut Cleansing Solutions Using the Split Dose Intake in Healthy Subjects
This study is to investigate the effect of various modified low volume polyethylene glycol (PEG) 3350 and ascorbic acid/ascorbate (PEG+ASC)-based gut cleansing solutions on stool output in healthy subjects.
- Trial name
- OUT (NCT01834742)
- Testing
- NER1006, Moviprep
- Where
- 2 sites in Romania
- Volunteers
- 161 people, healthy volunteers welcome
- Sponsor
- Norgine
Malnutrition
Evaluating the Impact of the Food Support Program (Programa de Apoyo Alimentaria)
The Programa de Apoyo Alimentaria (PAL) started in 2003 and is targeted to communities in Mexico that do not receive benefits from other federal food aid programs, have less than 2,500 inhabitants and a high level of…
- Trial name
- NCT01304888
- Testing
- Cash + nutrition education, Food basket + nutrition education, Food basket w/o nutrition education
- Where
- Mexico
- Volunteers
- 6,687 people
- Sponsor
- Instituto Nacional de Salud Publica, Mexico
Impacted Mandibular Third Molar
Does Vitamin C Improve Postoperative Healing
This randomized, split-mouth clinical trial investigates the effect of oral vitamin C supplementation on postoperative recovery following the surgical extraction of impacted mandibular third molars.
- Trial name
- NCT07012564
- Testing
- Vitamin C
- Where
- Turkey (Türkiye)
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Heart Arrest, Out-Of-Hospital, Biomarkers
Impact of Vitamin C on Biomarkers of Neurologic Injury in Survivors of Cardiac Arrest
Out-of-hospital cardiac arrest (OHCA) is one of the leading cause of death in the world. In Slovenia approximately 25% of resuscitated patients survives to discharge from hospitals, usually with poorer functional status.
- Conditions
- Heart Arrest, Out-Of-Hospital, Biomarkers, Oxidative Stress, Neurological Injury
- Trial name
- NCT04563000
- Testing
- Vitamin C
- Where
- Slovenia
- Volunteers
- 150 people
- Sponsor
- University Medical Centre Maribor
Osteoarthritis, Overweight and Obesity
Epigenorm Antivir Combined With Acupuncture for the Treatment of Osteoarthritis Patients Who Are Overweight or Obese
The study evaluates analgesic, antiinflammatory and metabolic effects of a supplement Epigenome-Antivir (extracts of glycyrrhiza roots, hippophae rhamnoides leaves, curcumin, green tea, and vitamin C) combined with acupuncture in…
- Trial name
- NCT03540186
- Testing
- Epigenorm Antivir, Acupuncture
- Where
- Russia
- Volunteers
- 15 people
- Sponsor
- Federal State Budgetary Scientific Institution, Research Institute of Fundamental and Clinical Immunology
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