Clinical trials: Water
Percutaneous Coronary Intervention
Chewed Versus Integral Pill of Ticagrelor
Hypothesis The primary question the investigators propose to answer is whether all patients undergoing percutaneous coronary intervention (PCI) with stent deployment who receive chewed ticagrelor will demonstrate more rapid drug…
- Trial name
- NCT03708588
- Testing
- Ticagrelor
- Where
- United States
- Volunteers
- 112 people
- Sponsor
- Wake Forest University Health Sciences
Type 2 Diabetes
Acute Studies on the Glycemic Index After Intake of Different Sorts of Barley in Subjects With Type 2 Diabetes
In a series of double-blinded randomized cross-over acute studies, the investigators want to study the effects of different types of barley on the glycemic index (GI) in subjects with type 2 diabetes.
- Trial name
- NCT04646746
- Testing
- 100% wheat, 50% nude barley and 50% wheat, 75% nude barley and 25% wheat
- Where
- Denmark
- Volunteers
- 20 people
- Sponsor
- University of Aarhus
Bioequivalence, Diabetes Mellitus, Type 2
Comparative Bioavailability Study of Metformin/Sitagliptin 850 mg/50 mg Tablets in Healthy Male and Female Volunteers
The objective of this study was to evaluate and compare the bioavailability and therefore to assess the bioequivalence of two different formulations of metformin/sitagliptin after a single oral dose administration under fed…
- Trial name
- NCT05549570
- Testing
- Sitagliptin/Metformin HCl 50/850 mg film-coated tablet
- Where
- Canada
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Galenicum Health
Muscle Protein Synthesis
Effects of Ingesting Multiple Boluses of Collagen on Muscle & Skin Connective Protein Synthesis in Vivo in Humans
Rationale: Collagen protein is the central structural component of extracellular connective tissues within skeletal muscle, bone, cartilage and skin.
- Trial name
- CODIAK (NCT06435637)
- Testing
- Collagen protein, Resistance exercise
- Where
- Netherlands
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Urinary Bladder Neoplasms, Prostatic Neoplasms
Lymphedema After Urologic Surgery
Lymphedema of the extremities is common after lymph node surgery in treating several forms of cancer, e.g., breast cancer. However, very little is known of the occurrence of lymphedema of the lower extremities after urologic…
- Conditions
- Urinary Bladder Neoplasms, Prostatic Neoplasms, Testicular Neoplasms, Penile Cancer
- Trial name
- NCT05264337
- Testing
- Self-reported lymphedema, Dielectric constant ratio, Limb volume
- Where
- 2 sites in Sweden
- Volunteers
- 400 people
- Sponsor
- Vastra Gotaland Region
Diabetes, Lower Extremity Arterial Disease
Effectiveness Study of Hydrotherapy Against Pain and Other Symptoms in Diabetes-induced LEAD
The purpose of the study is to investigate whether the hydrotherapy are effective in against pain and other symptoms in diabetes-induced LEAD.
- Trial name
- NCT01948037
- Testing
- hydrotherapy
- Where
- China
- Volunteers
- 70 people
- Sponsor
- Jinling Hospital, China
Pain, Shoulder
The Effect of Hot Application on Post Laparoscopic Shoulder Pain and Analgesic Use
The aim of this study; To evaluate the effect of hot application on postlaparoscopic shoulder pain and analgesic use in patients undergoing upper laparoscopic surgery in general surgery.
- Trial name
- NCT05334797
- Testing
- Local heat therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Cukurova University
Glucose Metabolism, Metabolic Syndrome
The SIMBA Project - The Effect of a Prebiotic Supplement on Glucose Metabolism and Gut Microbiota in Obese Adults
Modulation of the gut microbiota via administration of pro- and prebiotics have been proposed to contribute to weight loss and reduce plasma glucose and serum lipid levels, improving the inflammatory state and decreasing the…
- Conditions
- Glucose Metabolism, Metabolic Syndrome, Gut Microbiota
- Trial name
- SIMBA (NCT04120051)
- Testing
- Fermented canola-seaweed
- Where
- Denmark
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Healthy Men and Women
The Effects of Dragon Fruit Consumption on Vascular Function.
Native to South America and South East Asia, the dragon fruit (pitaya) has become increasingly popular world-wide due to their vivid hue and bizarre structure.
- Trial name
- NCT03995602
- Testing
- Dragon fruit juice drink
- Where
- United Kingdom
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- King's College London
Overweight
Quinoa Effects on Glycemic Index and Satiety
The purpose of this study is to to assess the glycemic index and the satiating properties of different Quinoa varieties, using a Visual Analogue Scale in a sample of healthy overweight subjects.
- Trial name
- NCT02621502
- Testing
- Quinoa variety 1, Quinoa variety 2, Quinoa variety 3
- Where
- Spain
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Instituto de Investigación Hospital Universitario La Paz
Heart Failure, Hyponatremia
The Effect of Fluid Restriction in Congestive Heart Failure Complicated With Hyponatremia
The purpose of this study is to determine the effect of fluid restriction and the neurohormonal mechanisms in the development of hyponatremia in patients with congestive heart failure and hyponatremia.
- Trial name
- Decongest (NCT01748331)
- Testing
- Fluid restriction
- Where
- 2 sites in Denmark
- Volunteers
- 40 people
- Sponsor
- Finn Gustafsson
Postoperative Pain After Endodontic Treatment, Dental Anxiety
Effect of Intracanal Cryotherapy on Pain, Anxiety, and Salivary Irisin After Root Canal Treatment
Some people feel pain after a root canal treatment. This study will test whether intracanal cryotherapy, a final rinse of the tooth with cold sterile saline, can reduce this pain compared with a room-temperature rinse.
- Conditions
- Postoperative Pain After Endodontic Treatment, Dental Anxiety, Root Canal Treatment
- Trial name
- CRYO-IRISIN (NCT07889050)
- Testing
- Intracanal cryotherapy, Standard room-temperature irrigation
- Where
- Turkey (Türkiye)
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Alanya Alaaddin Keykubat University
Respiratory Status
Effectiveness of Breathing Exercises as Therapeutic Play on Respiratory Status Among Children With Lower Respiratory Tract Disorders
The study evaluates the effectiveness of Breathing Exercises as Therapeutic Play on respiratory Status among children with Lower respiratory Tract Disorders.
- Trial name
- NCT03225274
- Testing
- Breathing Exercises as Therapeutic Play
- Volunteers
- 60 people
- Sponsor
- Maharishi Markendeswar University (Deemed to be University)
Urethrocutaneous Fistulas
2-octyl Cyanoacrylate for Closure of Urethrocutaneous Fistula.
Urethrocutaneous fistulae (UCF) represent one of the most frequent causes of morbidity after urethroplasty. Hypospadias can be repaired using different surgical techniques, but regardless of technique, the incidence of UCF ranges…
- Trial name
- NCT02115191
- Testing
- 2-octylcyanoacrylate, Surgical reintervention
- Where
- Mexico
- Volunteers
- 42 people
- Sponsor
- Instituto Mexicano del Seguro Social
Healthy, Prediabetic State
Effect of a Collagen Hydrolysate on Postprandial Blood Glucose Profile in Prediabetic and Healthy Subjects
To investigate the effect of two different dosages collagen hydrolysate (CH) on postprandial blood glucose and insulin profile in prediabetic and normo-glycaemic subjects.This will be investigated in a cross-over randomized…
- Trial name
- NCT05887791
- Testing
- Collagen hydrolysate
- Where
- Germany
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Rousselot BVBA
Healthy Volunteers, Erythritol
SUVY VerSus SAccharose (SUVISA)
Sugar substitutes are increasingly used to reduce sugar intake. SÜVY is a food ingredient combining erythritol and polydextrose.
- Trial name
- SUVISA (NCT07901491)
- Testing
- SÜVY, Sucrose
- Where
- France
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Minerais SAS
Chronic Kidney Disease; Iron Deficiency Anemia
A Study to Evaluate the Safety (Compared to Iron Sucrose), Efficacy and Pharmacokinetics of Ferumoxytol for the Treatment of Iron Deficiency Anemia (IDA) in Pediatric Subjects With Chronic Kidney Disease (CKD)
Primary Objectives: To evaluate the safety (compared to iron sucrose) and efficacy of ferumoxytol in pediatric CKD subjects with iron deficiency anemia (IDA) or who are at risk of development of IDA Secondary Objective: To…
- Trial name
- NCT03619850
- Testing
- Ferumoxytol, Iron sucrose
- Where
- 21 sites in United States, Hungary and 3 more
- Volunteers
- 129 people
- Sponsor
- AMAG Pharmaceuticals, Inc.
Aligner Staining
Cleaning Agents Impact on Invisalign Aligners: A Cross-Over Randomized Trial
Today, the increasing aesthetic expectations of the patients, showing its effect in the field of orthodontics, leads to the orientation towards aesthetic materials.
- Trial name
- İnvisalign (NCT05213650)
- Testing
- non-abrasive toothpaste, abrasive toothpaste, Efferdent
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Bezmialem Vakif University
Incontinence, Erectile Dysfunction Following Radical Prostatectomy
Additional Effects of Aerobic and Resistance Exercises to Pelvic Floor Muscle Training After Radical Prostatectomy
In the literature, studies about urinary symptoms after radical prostatectomy (RP) are generally focused on urinary incontinence (UI), and studies about sexual symptoms are focused on erectile dysfunction (ED).
- Trial name
- NCT06126874
- Testing
- Patient Education, Pelvic Floor Muscle Training, Aerobic Exercise Training
- Where
- Turkey (Türkiye)
- Volunteers
- 38 people
- Sponsor
- Hacettepe University
Nicotine Dependence
Improving the Efficacy of Anti-Nicotine Immunotherapy
The purpose of this study is to find out how vaccine-induced antibodies change the way the body processes nicotine from cigarettes. These antibodies absorb nicotine and can reduce nicotine levels in the brain.
- Trial name
- PETNic002 (NCT01280968)
- Testing
- NIC002 in Aluminum hydroxide (Alum)
- Where
- 2 sites in United States
- Volunteers
- 52 people
- Sponsor
- Alexey Mukhin
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