Clinical trials: Water, completed
Constipation
Clinical Study of Resistant Starch in Improving Constipation
Constipation is one of the most common gastrointestinal (GI) disorders in clinical practice, with approximately 11-20% of adults worldwide suffering from constipation.
- Trial name
- NCT06292949
- Testing
- Resistant starch
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Huaping Xie
Arteriosclerosis, Intracranial Arteriosclerosis
Identifying the Anti-Blood-Clotting Compounds in Garlic
This study will seek to identify the compound(s) in garlic that is (are) responsible for its ability to prevent the formation of blood clots (prevent platelet aggregation) and to determine the maximally effective dose and…
- Trial name
- NCT00200785
- Testing
- garlic powder added to ambient water, garlic powder added to boiling water
- Where
- United States
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- National Center for Complementary and Integrative Health (NCCIH)
Well-Being (Psychological Flourishing), Depression
The Seniors COvid-19 Pandemic and Exercise Study
The purpose of this study is to evaluate different types of exercise programs (virtual group-based exercise program; personal exercise program; wait-list control) across 12-weeks on the physical and mental health of older adults…
- Conditions
- Well-Being (Psychological Flourishing), Depression, Quality of Life, Loneliness
- Trial name
- SCOPE (NCT04412343)
- Testing
- Virtual Group Intervention, Personal Exercise Intervention
- Where
- Canada
- Volunteers
- 241 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Alcohol Use Disorder
The Efficacy of Probiotics for the Treatment of Alcohol Use Disorder Among Adult Males
This two-armed, parallel-group, double-blind, multi-center randomized control trial (RCT) aims to evaluate the efficacy of probiotic supplement compared with placebo in ameliorating alcohol craving and severity of alcohol use…
- Trial name
- NCT05830708
- Testing
- Lactobacillus sp. probiotic
- Where
- China
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Universiti Sains Malaysia
Sepsis
Study of Early Enteral Dextrose in Sepsis
This study is a prospective single-center randomized double-blinded placebo-controlled clinical trial testing the effects of early enteral dextrose as a therapeutic agent in critically ill patients with sepsis.
- Trial name
- SEEDS (NCT03454087)
- Testing
- Enteral Dextrose Infusion, Free Water Infusion
- Where
- United States
- Volunteers
- 58 people
- Sponsor
- University of Pittsburgh
Obesity
Oral Glucosestimulation After Gastric Bypass Surgery
The objective of this study is to examine gastric emptying and satiety hormones after oral glucose stimulation in 2 different concentrations in morbidly obese patients after Roux-en-Y-gastric-Bypass.
- Trial name
- NCT01851616
- Testing
- 25g of glucose in 200ml tap water, given orally (plus 50 mg 13C-sodium acetate), 10g Glucose in 200ml tap water given orally (plus 50 mg 13C-sodium acetate)
- Where
- Switzerland
- Volunteers
- 8 people
- Sponsor
- University Hospital, Basel, Switzerland
Effect of Irrigation Activation on Periapical Healing
Effect of Irrigation-Activation Techniques on Healing in Large Periapical Lesions
The aim of this study was to highlight the healing rates of large periapical lesions after different irrigation activation treatments as manual dynamic activation (MDA), passive ultrasonic irrigation (PUI), shock wave-enhanced…
- Trial name
- NCT06204887
- Testing
- Manual dynamic activation, Passive ultrasonic activation, Laser activation
- Where
- Turkey (Türkiye)
- Volunteers
- 97 people, healthy volunteers welcome
- Sponsor
- Recep Tayyip Erdogan University
Narcolepsy
Patient Narcoleptic Treated With BF2.649 (Pitolisant) in add-on to Sodium Oxybate (HARMONY IV)
This is a multicentric international phase III, double blind randomized study assessing efficacy and safety in parallel group of BF2.649 (pitolisant) compared to placebo in add-on to sodium oxybate of narcoleptic patients with…
- Trial name
- HARMONY IV (NCT01789398)
- Testing
- BF2.649
- Where
- France
- Volunteers
- 51 people
- Sponsor
- Bioprojet
Cerebrovascular Accidents
Effect of Combined Therapy on Neglect Syndrome in Stroke Patients
The purpose of the current study is to evaluate motor and neglect recovery of stroke patients produced by CIT using kinematic and oculomotor assessment, together with conventional clinical measures.
- Trial name
- NCT00784706
- Testing
- EP, CIT, conventional therapy
- Where
- Taiwan
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
Menstrual Pain
Effectiveness of PEA Compared to Placebo on Acute Menstrual Pain
This is a double blind, randomised, placebo-controlled trial to evaluate orally-dosed Palmitoylethanolamide (PEA) compared to placebo on menstrual pain in otherwise healthy participants 18 years and over.
- Trial name
- NCT05810116
- Testing
- Levagen+, Microcrystalline cellulose
- Where
- Australia
- Volunteers
- 80 people
- Sponsor
- RDC Clinical Pty Ltd
Premature Ejaculation
FTIH Study With GSK958108
This study is the first administration of GSK958108 to man. The study will evaluate the safety, tolerability and pharmacokinetics of single ascending doses of GSK958108 and evaluate the effect of food on GSK958108 pharmacokinetics
- Trial name
- NCT00664365
- Testing
- GSK958108
- Where
- United Kingdom
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Ventilator Associated Pneumonia
Oral Care Interventions and Ventilator Associated Pneumonia in Critically Ill Children
This experimental study aims to verify the influence of the oral hygiene performance with chlorhexidine digluconate 0.12% in the development of VAP in children.
- Trial name
- NCT01083407
- Testing
- 0.12% Chlorhexidine Digluconate, Toothbrushing
- Volunteers
- 146 people
- Sponsor
- Federal University of São Paulo
Electric Impedance, Pharmacokinetics
Bioelectrical Impedance Analysis as a Bedside Tool to Estimate Volume of Distribution of Hydrophilic Antimicrobials in Critically Ill Patients
Bioelectrical impedance analysis is studied as a bedside tool to estimate capillary leak in order to guide dosing of hydrophilic antimicrobials.
- Conditions
- Electric Impedance, Pharmacokinetics, Capillary Leak Syndrome
- Trial name
- NCT03410771
- Testing
- Monitor antibiotic exposure (PK profile), Bioelectrical impedance analysis to measure body composition
- Where
- Belgium
- Volunteers
- 68 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Severe Sepsis
Extravascular Lung Water Index in Severe Sepsis
To investigate whether extravascular lung water index (EVLI) is an independent predictor for multiorgan dysfunction syndrome (MODS) in patients with severe sepsis and to determine if increased EVLI may serve as an predictor for…
- Trial name
- EVLI in sepsis (NCT00986271)
- Testing
- EVLI was determinated by PiCCO plus system.
- Volunteers
- 67 people
- Sponsor
- Chang Gung Memorial Hospital
Pharmacokinetic
Investigation How CG5503 is Taken up and Excreted From the Body After 2 Minutes Intravenous Infusion With and Without Oral Co-administration of Charcoal
This was a Phase I study in 12 healthy male participants to compare the pharmacokinetic properties of CG5503 (how it is taken up and excreted from the body) after 2 minutes intravenous (i.v.) infusion with and without oral…
- Trial name
- NCT03951987
- Testing
- 4 ml CG5503, 5 g charcoal powder
- Where
- Germany
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Grünenthal GmbH
Chronic Kidney Disease
Impact of Increased Water Intake in Chronic Kidney Disease
The investigators have designed a randomized controlled trial to test whether increased water intake slows renal decline in patients with Stage-III Chronic Kidney Disease.
- Trial name
- WIT (NCT01766687)
- Testing
- Hydration
- Where
- Canada
- Volunteers
- 822 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Dental Plaque
Efficacy of Plaque Removal of a Novel Brushing Device
The purpose of this research study is to compare how a novel, automated mouthpiece-based toothbrushing device removes dental plaque compared to a manual toothbrush.
- Trial name
- NCT05038293
- Testing
- Automated mouthpiece-based toothbrush, Manual toothbrush
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- University of Washington
Familial Hypercholesterolemia - Homozygous
Study to Evaluate Efficacy and Safety of Inclisiran in Adolescents With Homozygous Familial Hypercholesterolemia
This was a pivotal phase III study designed to evaluate safety, tolerability, and efficacy of inclisiran in adolescents with homozygous familial hypercholesterolemia (HoFH) and elevated low density lipoprotein cholesterol (LDL-C).
- Trial name
- ORION-13 (NCT04659863)
- Testing
- Inclisiran
- Where
- 11 sites in United States, Canada and 6 more
- Volunteers
- 13 people
- Sponsor
- Novartis Pharmaceuticals
Gastrointestinal Injury, Acute Mountain Sickness
Gut-microbiota Targeted Nutritional Intervention for Gut Barrier Integrity at High Altitude
The aim of this randomized, crossover clinical trial is to determine the efficacy of a gut microbiota-targeted nutritional intervention containing a blend of fermentable fibers and polyphenols (FP) for mitigating increases in GI…
- Trial name
- NCT04111263
- Testing
- FP, High altitude, Sea level
- Where
- United States
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- United States Army Research Institute of Environmental Medicine
Exercise Performance
Effects of Beetroot Juice and Caffeinated Coffee on Exercise Performance in Recreationally Active Men
The goal of this clinical trial was to evaluate how acute intake of beetroot juice, caffeinated coffee, and their combination affected aerobic and anaerobic exercise performance in healthy recreationally active men.
- Trial name
- NCT07797062
- Testing
- Beetroot juice, Caffeinated Turkish Coffee, Water
- Where
- Turkey (Türkiye)
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Acibadem University
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