Clinical trials: Water
Polycystic Ovary Syndrome, Infertility, Female
Effect of ALA Combined With Letrozole on Polycystic Ovary Syndrome Clinical Outcome in Infertile Females
This research study aims to investigate the effect of adding Alpha lipoic acid (ALA) supplement to letrozole treatment in infertile women with polycystic ovary syndrome (PCOS).
- Trial name
- NCT06418347
- Testing
- Alpha lipoic acid, Letrozole
- Where
- Egypt
- Volunteers
- 150 people
- Sponsor
- Ain Shams University
Periodontitis
The Novel Electrolyzed Water Spray Treatment Mild Periodontitis
The purpose of this study is to test whether spraying the tooth of patients by use of the novel electrolyzed water spray will produce improvement in the condition of mild periodontitis.
- Trial name
- NCT05770258
- Testing
- The novel electrolyzed water spray
- Where
- China
- Volunteers
- 12 people
- Sponsor
- Dove Medical Press Ltd
High Grade Glioma
Predicting Sites of Tumour Progression in the Invasive Margin of Glioblastomas (PRaM-GBM Study)
Brain tumours are the leading cause of cancer deaths in children, men under the age of 45 and women under the age of 25. Glioblastoma is the most common and most malignant primary tumour.
- Trial name
- PRaM-GBM (NCT03294434)
- Testing
- Diffusion tensor Imaging (DTI)
- Where
- United Kingdom
- Volunteers
- 147 people
- Sponsor
- CCTU- Cancer Theme
Pregnancy, Climate Change Anxiety
Climate Change Education Based on the IMB Model for Pregnant Women
Climate change can affect the health of pregnant women and their babies, for example through extreme heat and air pollution. Many pregnant women worry about these effects but do not know how to protect themselves.
- Conditions
- Pregnancy, Climate Change Anxiety, Risk Perception, Fear of Childbirth
- Trial name
- NCT07871032
- Testing
- IMB-Based Climate Change Education
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Cukurova University
Amyotrophic Lateral Sclerosis (ALS)
FHND1002 for ALS Treatment: Phase 2
This is a Phase II clinical trial evaluating the effectiveness and safety of an investigational drug, FHND1002 granules, in adults with Amyotrophic Lateral Sclerosis (ALS).
- Trial name
- FHN-ALS2 (NCT07138014)
- Testing
- FHND1002 100mg, FHND1002 200mg
- Volunteers
- 180 people
- Sponsor
- Jiangsu Chia Tai Fenghai Pharmaceutical Co., Ltd.
Skin Care
Evaluation of the Cosmetic Benefit of a Skin Cream in Healthy Females With Mild to Advanced Photo-damaged Facial Skin Who Have Undergone a Glycolic Acid Facial Peel Procedure
Evaluation of the local tolerance and cosmetic efficacy of a topical skin care formulation in healthy female participants with mild to advanced photo-damaged facial skin who have undergone a 70% Glycolic Acid facial peel…
- Trial name
- NCT03103906
- Testing
- Cream (Test product), Cleanser (Reference Product), Sunscreen (Reference Product)
- Where
- 2 sites in Brazil
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
CHRONIC POST-TRAUMATIC NEUROPATHIC PAIN IN ANKLE AND FOOT
Pilot RCT of Efficacy of Perineural Local Anesthetics and Steroids for Chronic Post-traumatic Ankle and Foot Pain
Injections of local anesthetics (freezing) and steroids are often performed around injured nerves in individuals with nerve injury-related pain.
- Trial name
- PREPLANS (NCT02680548)
- Testing
- 0.9% saline, 0.25% bupivacaine hydrochloride injectable suspension USP, 4mg/cc methylprednisolone acetate injectable suspension USP
- Where
- Canada
- Volunteers
- 8 people
- Sponsor
- University Health Network, Toronto
Fibroid Uterus, Fibroid Tumor
Effects of Simvastatin on Uterine Leiomyoma Size
The study aims to study the effect of simvastatin on the size of uterine fibroids.
- Conditions
- Fibroid Uterus, Fibroid Tumor, Leiomyoma, Fibromyoma
- Trial name
- NCT03400826
- Testing
- Simvastatin 40mg
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Johns Hopkins University
Dentine Hypersensitivity
Efficacy of Potassium Nitrate Solution in Reducing Dentinal Hypersensitivity
An exploratory study investigating the direct application of potassium nitrate (KNO3) solutions of different concentrations in reducing dentine hypersensitivity.
- Trial name
- NCT01115452
- Testing
- 5% Potassium nitrate, 2.5% Potassium nitrate, Sterile water
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- GlaxoSmithKline
Achalasia Cardia
Comparison of Balloon Dilatation and Per Oral Endoscopic Myotomy in Children With Achalasia Cardia
To compare the efficacy of balloon dilatation (BD) and per oral endoscopic myotomy (POEM) in improving the symptoms of children with achalasia in short and long term Presently most guidelines such as American Society for…
- Trial name
- NCT07167355
- Testing
- POEM, BALLOON DILATATION
- Volunteers
- 70 people
- Sponsor
- Asian Institute of Gastroenterology, India
Fluid Overload, Water Electrolyte Imbalance
The Effect of Crystalloids and Colloids on Visceral Blood Flow
Patients often require fluid replacement during and after an operation. This is usually given through veins in the arm using an intravenous cannula and doctors have traditionally used fluid containing sodium chloride (saline).
- Conditions
- Fluid Overload, Water Electrolyte Imbalance, Acid Base Imbalance
- Trial name
- NCT01087853
- Testing
- Crystalloid, Colloid
- Where
- United Kingdom
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- University of Nottingham
Exercise
Carbohydrate Feeding Frequency, Muscle Glycogen and Exercise Capacity in Runners
The aim of this study is to investigate the effects of regular sucrose feeds compared to a single large bolus given late in exercise, on muscle glycogen utilisation, exercise capacity and other markers of metabolism during running
- Trial name
- NCT03749785
- Testing
- Regular carbohydrate feeding, Single carbohydrate bolus
- Where
- United Kingdom
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- University of Bath
Satiety, Postprandial Glycemia
Effect of Lemon Juice and Apple Cider Vinegar on Postprandial Blood Glucose and Satiety in Healthy Individuals
This clinical study aims to examine how acidic drinks (lemon juice and apple cider vinegar) affect blood sugar when consumed with a starchy food.
- Trial name
- NCT07563985
- Testing
- Control (Water + White Bread), Lemon Juice 50 g, Lemon Juice 100 g
- Where
- Turkey (Türkiye)
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Alanya Alaaddin Keykubat University
Gingival Displacement
The Efficacy of Different Gingival Displacement Methods Before Definitive Digital Impression
This study aims to evaluate and compare the efficacy of four methods in achieving vertical and horizontal gingival tissue displacement to be captured by optical digital impression.
- Trial name
- NCT06132815
- Testing
- Laser troughing, Retraction cord and astringent, Cordless retraction paste with astringent
- Where
- Egypt
- Volunteers
- 32 people
- Sponsor
- Alexandria University
Healthy
Effects of Time-Restricted Fasting on the Postprandial Glycemic Responses
The goal of this clinical trial is to investigate whether fasting timing has a significant effect on postprandial glycemic responses in healthy adults. The main questions it aims to answer are: 1.
- Trial name
- NCT05913635
- Testing
- Consumption of lunch and dinner, with no breakfast, Consumption of breakfast and lunch, with no dinner
- Where
- China
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Fudan University
Type2 Diabetes
Effects of Fructose/Glucose-rich Diet on Brown Fat in Healthy Subjects (GB7)
Activating brown and beige adipose tissue (herein described as BAT) has been recently recognized as a potential means to increase energy expenditure and lower blood glucose, however, BAT activity appears to be reduced with…
- Trial name
- GB7 (NCT03188835)
- Testing
- Diet, cold exposure, 18FDG
- Where
- Canada
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Université de Sherbrooke
Xerostomia
Comparing Over-the-counter Dry Mouth Remedies After Radiation
The purpose of this study is to compare the effectiveness of over-the-counter remedies for dry mouth.
- Trial name
- NCT00595933
- Testing
- sugar-free chewing gum, chewing gum, mouth rinse
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- University of Oklahoma
Crohn Disease
Value of PET/MR Enterography in the Assessment of Crohn's Disease Using a Collagen-binding Radiotracer.
In this study twenty-five (25) subjects with Crohn's disease scheduled for possible surgical intervention will be recruited for this study and a PET/MR scan using the collagen-binding radiotracer will be performed.
- Trial name
- NCT06252493
- Testing
- Radiotracer Injection, Contrast Media, Magnetic Resonance, Blood Draw
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Massachusetts General Hospital
Coeliac Disease, Probiotic
Efficacy of Symprove Probiotics in Coeliac Disease
Coeliac Disease (CD) is a lifelong autoimmune condition where eating gluten (a protein found in wheat, barley, and rye) causes damage to the small intestine. It affects around 1 in 100 people.
- Conditions
- Coeliac Disease, Probiotic, Gluten
- Trial name
- NCT07360106
- Testing
- Symprove Probiotic
- Where
- United Kingdom
- Volunteers
- 24 people
- Sponsor
- Sheffield Teaching Hospitals NHS Foundation Trust
Gastric Ulcer
A 12-month, Phase 3, Open-label, Multi-center Study to Evaluate the Long-term Safety of PN400 (VIMOVO)
This study uses an open-label design and will be conducted in approximately 60 sites aiming to enroll a total number of 200 subjects to ensure that at least 100 subjects will have 12 months exposure to PN400 (VIMOVO).
- Trial name
- NCT00527904
- Testing
- PN400 (VIMOVO), PN 400 (VIMOVO)
- Where
- United States
- Volunteers
- 239 people
- Sponsor
- POZEN
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