Clinical trials: Water
Healthy Response to Probiotics
Defining the Normal Human Response to Probiotics
The study is a mono-center, randomized, semi-blinded, placebo-controlled, cross-over, proof-of principle study in healthy volunteers. The study will determine the probiotic effect of LGG on intestinal tissue and intestinal cells
- Trial name
- NCT03140878
- Testing
- LGG
- Where
- Denmark
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Chr Hansen
Preterm Neonate Analgesia
Melatonin As an Analgesic in Preterm Neonate
Melatonin (N-acetyl-5-methoxytryptamine) is a neurohormone secreted by the pineal gland with several important functions, including regulation of the circadian rhythms, antioxidant and anti-inflammatory effects, accumulating…
- Trial name
- NCT05971485
- Testing
- Melatonin 10 mg
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Ain Shams University
Functional Dysphonia, Resonance Tube Voice Therapy
Management of Non-Organic Dysphonia in Adults.
The purpose of this study is to determine the effect of a semi-occluded vocal tract training program, "Resonant Tube Therapy," versus the "Traditional Smith-accent Method" on the quality of voice in patients with Non-Organic…
- Conditions
- Functional Dysphonia, Resonance Tube Voice Therapy, Smith Accent Method Therapy
- Trial name
- NCT06856785
- Testing
- Resonance Tube Voice Therapy in Water
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Sohag University
Oncoplastic Breast Surgery, Breast Cancer
Aesthetic Outcomes of Oncoplastic Breast Surgery for Breast Cancer in the Upper Inner Quadrant
Oncoplastic breast surgery, combining oncological resection with plastic surgical techniques, has emerged as an important surgical strategy to optimize conventional breast-conserving surgery.
- Conditions
- Oncoplastic Breast Surgery, Breast Cancer, Aesthetic Outcomes
- Trial name
- NCT05179304
- Testing
- Oncoplastic technique with a droplet-shaped glandular flap
- Where
- China
- Volunteers
- 109 people
- Sponsor
- Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Obesity, Inflammation
Anti-Inflammatory Activities of Grapes in Humans at Risk for Cardiovascular Disease
The goal of the study is to determine whether grape consumption can reduce the risk of cardiovascular disease by reducing the presence of inflammatory molecules and positively altering cholesterol levels, lipid profiles, and…
- Trial name
- NCT01443884
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- USDA, Western Human Nutrition Research Center
Bowel Preparation
Prepackaged Nutritional Formulations Versus Restricted Diet for Bowel Preparation
In order to analyze the effectiveness and patient tolerance of the two bowel preparation regimens, the investigators will compare prepackaged semisolid nutritional formulations and restricted diet.
- Trial name
- NCT04776733
- Testing
- prepackaged semisolid nutritional formulations, restricted diet
- Where
- China
- Volunteers
- 196 people
- Sponsor
- Ningbo No. 1 Hospital
Allergic Rhinitis (Disorder)
Effectiveness Of Therapy With A Thermal Water Nasal Aerosol In Children With Seasonal Allergic Rhinitis
The purpose of this study was to evaluate the effects of Ischia thermal waters nasal irrigation on allergic rhinitis and airway inflammation during the period of natural exposure to parietaria pollen in children with allergic…
- Trial name
- NCT01326247
- Testing
- thermal waters nasal irrigation
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- Federico II University
Tuberculosis
Safety and Challenge Study of BCG TICE(R) Vaccination to Test Tuberculosis Immunity in Heathy Humans
A nonrandomized, open-label trial will be conducted with a total of 64 healthy male and non-pregnant females, ages 18-45 years. Participants in Group A will enroll 32 participants to receive 2x10^6 colony- forming units CFU…
- Trial name
- NCT06845358
- Testing
- BCG TICE strain, Sodium Chloride, 0.9%, Sterile Water for Injection
- Volunteers
- healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Alzheimer Disease
A Study to Evaluate the Effects of JNJ-54861911 on Amyloid Beta Processing in Cerebrospinal Fluid and Plasma in Patients With Prodromal Alzheimer's Disease
The purpose of this study is to evaluate the safety, tolerability, pharmacokinetics, and pharmacodynamics of JNJ-54861911 in patients with prodromal Alzheimer's disease (pAD).
- Trial name
- NCT01978548
- Testing
- JNJ-54861911 10 mg, JNJ-54861911 50 mg
- Where
- 10 sites in Belgium, Netherlands and 2 more
- Volunteers
- 45 people
- Sponsor
- Janssen Research & Development, LLC
LLIN, PBO LLIN, IRS, Larviciding
Adaptive Interventions for Optimizing Malaria Control: a Cluster-Randomized SMART Trial
In the past decade, massive scale-up of long-lasting insecticidal nets (LLINs) and indoor residual spraying (IRS) have led to significant reductions in malaria mortality and morbidity.
- Trial name
- NCT04182126
- Testing
- Regular long-lasting insecticidal nets, LLIN plus Piperonyl butoxide-treated LLIN, Long-lasting microbial larvicide
- Where
- 2 sites in United States, Kenya
- Volunteers
- 122,872 people, healthy volunteers welcome
- Sponsor
- University of California, Irvine
Irritable Bowel Syndrome
Effect of Cannabinoid Agonist on Gastrointestinal and Colonic Motor Functions in Patients With Irritable Bowel Syndrome (IBS)
Irritable bowel syndrome (IBS) affects about 15% of the U.S. population. There are still no effective and safe medications approved for the treatment of abdominal pain associated with bowel symptoms in IBS.
- Trial name
- NCT01253408
- Testing
- Dronabinol
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- Mayo Clinic
Type 2 Diabetes Mellitus
To Evaluate the Food Effect on Pharmacokinetic Profiles and Safety in Healthy Volunteers
This is a randomized, open-label, single dose, crossover, phase 1 trial to evaluate the food effect on pharmacokinetic profiles and safety of CKD-383 in healthy volunteers
- Trial name
- NCT06492655
- Testing
- CKD-383(Fed), CKD-383(Fasted)
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Chong Kun Dang Pharmaceutical
Irritable Bowel Syndrome, IBS - Irritable Bowel Syndrome
Human Milk Oligosaccharides (HMOs) for Irritable Bowel Syndrome (IBS)
To assess the effects of a Human Milk Oligosaccharide mix given once daily for 12 weeks on stool consistency and abdominal pain compared to placebo in individuals with Irritable Bowel Syndrome (IBS).
- Trial name
- HIBS (NCT05205785)
- Testing
- Human Milk Oligosaccharide Mix
- Where
- Ireland
- Volunteers
- 204 people
- Sponsor
- dsm-firmenich Switzerland AG
Constipation
Clinical Study of Resistant Starch in Improving Constipation
Constipation is one of the most common gastrointestinal (GI) disorders in clinical practice, with approximately 11-20% of adults worldwide suffering from constipation.
- Trial name
- NCT06292949
- Testing
- Resistant starch
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Huaping Xie
Pediculosis, Head Louse Infestation
Two Treatment Regimens of Cocamide DEA Lotion for Head Lice
To assess the efficacy and safety of 10% Cocamide DEA using two treatment regimens in the eradication of head lice. To assess the ability of each treatment regimen to kill all viable ova and to assess patient acceptability of the…
- Trial name
- NCT02499549
- Testing
- cocamide diethanolamine
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- Medical Entomology Centre
Women, Excess Weight
Olive Leaf Extract, Meta-inflammation, Anxiety, and Excess Weight
Excess Weight is accompanied by a process that produces a low-grade inflammation state, called meta-inflammation. Anxiety is also associated with inflammation. Inflammation is closely related to oxidative stress.
- Conditions
- Women, Excess Weight, Anxiety Disorders
- Trial name
- NCT06485349
- Testing
- Olive Leaf Extract (OLE)
- Where
- Mexico
- Volunteers
- 70 people
- Sponsor
- University of Guadalajara
ROSAH
Evaluating the Safety and Tolerability of Orally Administered DF-003 in ROSAH Syndrome Patients
The purpose of this study is to evaluate the safety and tolerability of DF-003 in retinal dystrophy, optic nerve edema, splenomegaly, anhidrosis, and migraine headache (ROSAH) syndrome patients.
- Trial name
- NCT06395285
- Testing
- DF-003
- Where
- 5 sites in United States, Australia and 1 more
- Volunteers
- 12 people
- Sponsor
- Shanghai Yao Yuan Biotechnology Ltd. (also known as Drug Farm)
Menstrual Health Intervention, Product Use Issue
An MHH Intervention in Bangladesh Health Systems
Over 50% of Bangladeshi women and girls use old cloths as menstrual absorbents due to cost, comfort, and familiarity. A substantial proportion, comprising 52% of adolescent girls and 62% of women washed the cloths with soap and…
- Conditions
- Menstrual Health Intervention, Product Use Issue, Hygiene Practices and Knowledge, Menstrual Hygiene Management
- Trial name
- NCT07723885
- Testing
- Menstrual health and hygiene intervention
- Where
- Bangladesh
- Volunteers
- 700 people, healthy volunteers welcome
- Sponsor
- International Centre for Diarrhoeal Disease Research, Bangladesh
Arteriosclerosis, Intracranial Arteriosclerosis
Identifying the Anti-Blood-Clotting Compounds in Garlic
This study will seek to identify the compound(s) in garlic that is (are) responsible for its ability to prevent the formation of blood clots (prevent platelet aggregation) and to determine the maximally effective dose and…
- Trial name
- NCT00200785
- Testing
- garlic powder added to ambient water, garlic powder added to boiling water
- Where
- United States
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- National Center for Complementary and Integrative Health (NCCIH)
Well-Being (Psychological Flourishing), Depression
The Seniors COvid-19 Pandemic and Exercise Study
The purpose of this study is to evaluate different types of exercise programs (virtual group-based exercise program; personal exercise program; wait-list control) across 12-weeks on the physical and mental health of older adults…
- Conditions
- Well-Being (Psychological Flourishing), Depression, Quality of Life, Loneliness
- Trial name
- SCOPE (NCT04412343)
- Testing
- Virtual Group Intervention, Personal Exercise Intervention
- Where
- Canada
- Volunteers
- 241 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
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