Clinical trials: conventional surgery, completed
Pancreatic Cancer
Surgery Followed by Radiation Therapy and Chemotherapy in Treating Patients With Cancer of the Pancreas
RATIONALE: Surgery to remove the pancreas, some of the small intestine, and lymph nodes may be more effective treatment for cancer of the pancreas than surgery to remove the pancreas and some of the small intestine alone.
- Trial name
- NCT00003049
- Testing
- fluorouracil, leucovorin calcium, conventional surgery
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Mayo Clinic
REM Sleep Behavior Disorder
Gut Microbiota Across Early Stages of Synucleinopathy: From High-risk Relatives, REM Sleep Behavior Disorder to Early Parkinson's Disease
With the global ageing population, neurodegenerative disorders including synucleinopathy are major burdens to patients, carers and society.
- Trial name
- NCT03645226
- Testing
- Colonoscopy
- Where
- 2 sites in Hong Kong
- Volunteers
- 441 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Anxiety, Pain
The Effect Of Immersive Virtual Reality Application On Anxiety, Pain And Family Satisfaction In The Perioperative Process Of Children
An immersive virtual reality (VR) tour of the operating theater before surgery could reduce preoperative anxiety. The aims of this study were to analyze whether a preoperative virtual reality tour shows a reduction in anxiety in…
- Conditions
- Anxiety, Pain, Satisfaction
- Trial name
- NCT04824690
- Testing
- Virtual reality
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Abant Izzet Baysal University
Adenocarcinoma of the Prostate, Recurrent Prostate Cancer
Effect of Quercetin on Green Tea Polyphenol Uptake in Prostate Tissue From Patients With Prostate Cancer Undergoing Surgery
This randomized pilot phase I trial will evaluate if quercetin enhances the uptake of green tea polyphenols in the prostate tissue of men taking green tea extract and undergoing radical prostatectomy.
- Conditions
- Adenocarcinoma of the Prostate, Recurrent Prostate Cancer, Stage I Prostate Cancer, Stage IIA Prostate Cancer
- Trial name
- NCT01912820
- Testing
- green tea extract, quercetin, therapeutic conventional surgery
- Where
- 2 sites in United States
- Volunteers
- 32 people
- Sponsor
- Jonsson Comprehensive Cancer Center
Bariatric Surgery
The Metabolic Effects of Prebiotic Supplementation After Roux-en-Y Gastric Bypass Surgery
In this study, it is aimed to evaluate whether the addition of prebiotics to patients' post-operative diets increases Roux-en-Y Gastric Bypass surgery effects.
- Trial name
- NCT03517345
- Testing
- Prebiotic, Control
- Volunteers
- 32 people
- Sponsor
- Istanbul University
Vulvar Neoplasms, Skin Neoplasms
Prospective and Randomized Study to Evaluate Interest of Ultracision Use in Inguinal Lymph Nodes Curage
The purpose of this study is to evaluate the decrease of post-operative morbidity in inguinal lymphadenectomies realised for vulvar tumors and inferior limb skin tumors by use of Ultracision with regard to classical operative…
- Trial name
- NCT00224744
- Testing
- ultracision, classical lymphadenectomy
- Where
- 2 sites in France
- Volunteers
- 73 people
- Sponsor
- Institut Claudius Regaud
Airway Complication of Anesthesia, Septoplasty
Video Laryngeal Mask vs. Endotracheal Tube in Septoplasty
This single-center, prospective, observational, comparative study evaluated airway management using the SaCoVLM™ video laryngeal mask airway (VLMA) and a conventional endotracheal tube (ETT) in adult patients undergoing elective…
- Trial name
- NCT06950957
- Testing
- Video Laryngeal Mask Airway (VLMA), Endotracheal Tube (ETT)
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Samsun University
Dental Implant, Immediate Implant
Artificial Intelligence-Guided Versus Manual CBCT Planning for Immediate Implant Placement
This study evaluates whether artificial intelligence (AI)-based analysis of cone-beam computed tomography (CBCT) scans can support clinical decision-making for immediate dental implant placement in molar extraction sites.
- Conditions
- Dental Implant, Immediate Implant, Guided Bone Regeneration
- Trial name
- AI (NCT07459036)
- Testing
- AI assisted CBCt, Manual CBCT segmentation
- Where
- Egypt
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Shalash Dental education
Varicocele
Assessing the Rates of Major Complications in Combined Mini-incision Microscopic Varicocelectomy
The purpose of this study is to determine the rates of major post-varicocelectomy complications (Recurrence, Hydrocele and Testicular Atrophy) in patients operated with a new method named Combined Mini-incision Microscopic…
- Trial name
- CMMV (NCT02092311)
- Testing
- Combined Microscopic Varicocelectomy, Inguinal and Subinguinal varicocelectomy
- Where
- Iran
- Volunteers
- 570 people
- Sponsor
- Omid Fertility Center
Lower Leg Surgery, e.g. Ankle Fractures
Ultrasound-guided Nerve Blocks for the Sciatic and Saphenous Nerves: Characteristics of the Single Penetration Dual Injection (SPEDI) Technique
Background and aims: Ultrasound-guided (USG) nerve blocks of the sciatic nerve (popliteal level = PL) and the saphenous nerve (mid-femoral level = MFL) provides analgesia following leg surgery.
- Trial name
- NCT01815372
- Testing
- Single penetration dual injection (SPEDI) block technique to block the sciatic and the saphenous nerve with one needle penetration of the skin, The classical popliteal sciatic nerve block combined with the mid-femoral saphenous nerve block
- Where
- Denmark
- Volunteers
- 60 people
- Sponsor
- Bispebjerg Hospital
Incisional Hernia/Prevention and Control, Surgical Site Infection (SSI)
Comparison of Small-bite Versus Conventional Midline Fascial Closure in Abdominal Surgeries
This study investigates how different incision and fascial closure (suture) techniques used in abdominal surgery are associated with the development of incisional hernia, a common long-term complication after laparotomy.
- Trial name
- NCT07340918
- Where
- Turkey (Türkiye)
- Volunteers
- 217 people, healthy volunteers welcome
- Sponsor
- Muğla Sıtkı Koçman University
Myopia
Lower Femtosecond Laser Energy Levels Lead to Better Visual Recovery After Small-incision Lenticule Extraction for Myopia
Small-incision lenticule extraction (SMILE), the most recently developed refractive surgical technique, is being performed in a growing number of cases.
- Trial name
- NCT03111160
- Testing
- SMILE procedure using lower energy (100, 105, and 110 nJ), SMILE procedure using conventional energy (115 to 150 nJ)
- Where
- South Korea
- Volunteers
- 150 people
- Sponsor
- Yonsei University
Weight Loss
Volumetric Study of the Buttocks After Flap Augmentation in Buttocks Lifting
The development of bariatric surgery, its effectiveness and the reduction of complications are at the origin of massive weight loss, the corollary of which has been a clear increase in the demands of treatment of sequelae of…
- Trial name
- NCT03777618
- Testing
- gluteal augmentation with flap in circumferential body lift
- Where
- France
- Volunteers
- 30 people
- Sponsor
- University Hospital, Montpellier
Sarcoma
S0344 Intralesional Resection in Treating Patients With Chondrosarcoma of the Bone
RATIONALE: Intralesional resection is a less invasive type of surgery for chondrosarcoma of the bone and may have fewer side effects and improve recovery.
- Trial name
- NCT00096213
- Testing
- conventional surgery
- Where
- 23 sites in United States
- Volunteers
- 60 people
- Sponsor
- SWOG Cancer Research Network
Surgical Site Infection (SSI), Mediastinitis
Use of Platelet-Rich Plasma to Reduce Sternal Wound Complications After CABG With Median Sternotomy
The goal of this clinical trial is to learn whether applying autologous platelet-rich plasma (PRP) to the sternal wound during heart surgery improves wound healing and reduces complications after surgery.
- Conditions
- Surgical Site Infection (SSI), Mediastinitis, Delayed Wound Healing
- Trial name
- NCT07352020
- Testing
- Autologous Platelet-Rich Plasma (PRP) Application, Standard Sternal Wound Closure
- Where
- Pakistan
- Volunteers
- 98 people
- Sponsor
- Shaheed Zulfiqar Ali Bhutto Medical University
Gram-Negative Bacterial Infections, Sepsis
Early Use of Polymyxin B Hemoperfusion in Abdominal Sepsis
This clinical study designed as a prospective, open labelled, multi-centre, RCT will be carried out to evaluate if direct hemoperfusion with polymyxin B immobilized fiber column (PMX) is superior to conventional medical therapy…
- Conditions
- Gram-Negative Bacterial Infections, Sepsis, Septic Shock
- Trial name
- EUPHAS (NCT00629382)
- Testing
- Polymyxin B immobilized fiber column, Conventional medical therapy in the ICU
- Where
- Italy
- Volunteers
- 70 people
- Sponsor
- St. Bortolo Hospital
Aortic Stenosis Symptomatic
ACURATE TF™ Transfemoral Aortic Bioprosthesis for Implantation in Patients With Severe Aortic Stenosis (2011-03)
First-In-Man Study on the ACURATE TF™ Transfemoral Aortic Bioprosthesis Implantation in Patients with Severe Aortic Stenosis to collect human feasibility data pertaining to the safety and performance of the device.
- Trial name
- 2011-03 (NCT03752996)
- Testing
- ACURATE TF™ Aortic Valve System
- Where
- 5 sites in Brazil, Germany
- Volunteers
- 140 people
- Sponsor
- Symetis SA
Pelvic Organ Prolapse
SORD-BILL Vs Conventional Options During Sacral Colpopexy for POP
This prospective randomized pilot study is aimed to verify if the operative time of a standard laparoscopic sacral colpopexy associated to subtotal hysterectomy for the treatment of POP could be further reduced using PKS BILL…
- Trial name
- NCT02479685
- Testing
- PKS BILL-PKS PlasmaSORD Versus Conventional surgical techniques
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- Catholic University of the Sacred Heart
Lateral Patellar Compression Syndrome
Rehabilitation Efficacy of Low-Load Blood Flow Restriction Training for Lateral Patellar Compression Syndrome
The purpose of this study is to understand the effect of low-load blood flow restriction training on the rehabilitation effect of patients after lateral patellar compression syndrome surgery, and to observe the differences…
- Trial name
- LL-BFRT (NCT06988917)
- Testing
- the regular rehabilitation program, The blood flow limiting pressure band
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Peking University Third Hospital
Stomach Neoplasms, Cancer of Lymph Node
Lymph Node Metastasis in Extended Lymphadenectomy for Gastric Cancer From a CLASSIC Trial
The pattern of lymph node metastasis of the gastric cancer to each geographic lymph nose stations and the relation between each metastasis and survival are to be analyzed by retrospective review of medical records of who enrolled…
- Trial name
- NCT02298010
- Testing
- Capecitabine, oxaliplatin
- Volunteers
- 899 people
- Sponsor
- Seoul National University Hospital
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