Clinical trials: conventional surgery, completed
Health Behaviour
Combined Static and Dynamic Orthotic Treatment of the PIP Joint
Study Design: Randomized controlled clinical study. Introduction: Physiotherapeutic intervention aiming to restore mobility using different techniques as stretching, hot packs, exercises, therapeutic ultrasound and orthotics.
- Trial name
- StaDinOrt (NCT01914991)
- Testing
- dynamic extension contracture orthotic, conventional treatment Physical Therapy
- Where
- Spain
- Volunteers
- 62 people
- Sponsor
- University of Malaga
Acute Pancreatitis, Intra-abdominal Hypertension
Neostigmine Treatment of Acute Pancreatitis Combined With Intra-abdominal Hypertension
Acute pancreatitis(A) often complicated with Intra-abdominal Hypertension. After the onset of acute pancreatitis, capillary leakage causing ascites,upper gastrointestinal tract obstruction and paralytic ileus leading to an…
- Trial name
- NCT02543658
- Testing
- Neostigmine Methylsulfate 1 MG/ML, Conservative treatment
- Where
- China
- Volunteers
- 80 people
- Sponsor
- The First Affiliated Hospital of Nanchang University
Complete Hydatidiform Mole, Non-Metastatic Gestational Trophoblastic Tumor
Second Curettage in Treating Patients With Persistent Non-metastatic Gestational Trophoblastic Tumors
This phase II trial studies how well a second curettage (removal of the abnormal cancer cells in the uterus using a method of surgically removing the lining of the uterus) works in treating patients with gestational trophoblastic…
- Conditions
- Complete Hydatidiform Mole, Non-Metastatic Gestational Trophoblastic Tumor, Partial Hydatidiform Mole
- Trial name
- NCT00521118
- Testing
- Laboratory Biomarker Analysis, Therapeutic Conventional Surgery
- Where
- 29 sites in United States, Canada
- Volunteers
- 64 people
- Sponsor
- Gynecologic Oncology Group
Coronary Artery Bypass Graft
Prehabilitation and Coronary Artery Bypass Grafting
To evaluate the effects of Prehabilitation Resistance training on frailty and functional capacity in mild to moderate clinically frail patients awaiting Coronary Artery Bypass Grafting) CABG.
- Trial name
- NCT04993976
- Testing
- Resistant training (Prehabilitation), Active Comparator: Control group
- Where
- Pakistan
- Volunteers
- 74 people
- Sponsor
- Riphah International University
Breast Cancer
Early Rehabilitation After Immediate Reconstruction With TEI in Breast Cancer Patients
The purpose of the study is to find best post-operative rehabilitation protocol after total mastectomy and immediate reconstruction with tissue expander insertion.
- Trial name
- NCT03541161
- Where
- South Korea
- Volunteers
- 115 people
- Sponsor
- Samsung Medical Center
Rectal Cancer
Assessment of Efficacy and Safety of PD-1 Monoclonal Antibody Combined With IL-2 and CapeOX in Neoadjuvant Therapy for Locally Advanced Rectal Cancer Prior to Surgery: A Prospective, Multi-center, Randomized Controlled Study
The objective is to evaluate whether the neoadjuvant combination of tislelizumab (a PD-1 inhibitor) with interleukin-2 (IL-2) chemotherapy can significantly increase the Objective Response Rate (ORR) and the Pathological Complete…
- Trial name
- NCT06884670
- Testing
- Interleukin-2, Radiotherapy, Tislelizumab
- Where
- 4 sites in China
- Volunteers
- 130 people
- Sponsor
- The First Affiliated Hospital with Nanjing Medical University
Malignant Mesothelioma
Pemetrexed Disodium and Cisplatin Followed by Surgery With or Without Radiation Therapy in Treating Patients With Malignant Pleural Mesothelioma
RATIONALE: Drugs used in chemotherapy, such as pemetrexed disodium and cisplatin, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing.
- Trial name
- NCT00334594
- Testing
- Cisplatin, Pemetrexed, Therapeutic conventional surgery
- Where
- 13 sites in Germany, Switzerland
- Volunteers
- 153 people
- Sponsor
- Swiss Cancer Institute
Cataract, Cataract Mature
Study of the Efficiency and Workflow of Femtosecond Laser Assisted Cataract Surgery in a Spanish Public Hospital
Purpose: To assess the time-efficiency of a designated operation room (OR) workflow in the introduction of Femtosecond laser-assisted cataract surgery (FLACS, LenSx, Alcon®).
- Conditions
- Cataract, Cataract Mature, Cataract, Nuclear
- Trial name
- FLACS (NCT03931629)
- Testing
- CONVENTIONAL PHACO
- Volunteers
- 167 people
- Sponsor
- Fundación Pública Andaluza para la Investigación de Málaga en Biomedicina y Salud
Cardiac Toxicity, Sarcoma
Combination Chemotherapy Plus Dexrazoxane in Treating Patients With Newly Diagnosed Nonmetastatic Osteosarcoma
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining more than one drug may kill more tumor cells.
- Trial name
- NCT00003937
- Testing
- cisplatin, dexrazoxane hydrochloride, doxorubicin hydrochloride
- Where
- 148 sites in United States, Australia and 4 more
- Volunteers
- 253 people
- Sponsor
- Children's Oncology Group
Extra-articular Distal Radius Malunions
Computer Assisted Planning of Corrective Osteotomy for Distal Radius Malunion
The investigators are comparing post-operative patient-rated functional outcome between patients who undergo corrective osteotomy for extra-articular malunited distal radius fractures with and without computer assisted…
- Trial name
- NCT01897246
- Testing
- Corrective osteotomy with computer-assisted pre-operative planning, Corrective osteotomy with conventional preoperative planning
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Christine M. Kleinert Institute for Hand and Microsurgery
Thyroid Gland Undifferentiated (Anaplastic) Carcinoma
Pembrolizumab, Chemotherapy, and Radiation Therapy With or Without Surgery in Treating Patients With Anaplastic Thyroid Cancer
This phase II trial studies how well pembrolizumab, chemotherapy, and radiation therapy work with or without surgery in treating patients with anaplastic thyroid cancer.
- Trial name
- NCT03211117
- Testing
- Docetaxel, Doxorubicin Hydrochloride, Intensity-Modulated Radiation Therapy
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- Mayo Clinic
Sentinel Lymph Node, Early Gastric Cancer
Feasibility Study of Sentinel Navigation Surgery After Non-curative Endoscopic Resection
Purpose: To prove the feasibility of sentinel node navigation surgery (SNNS) in early gastric cancer patients with the risk of lymph node metastasis after endoscopic resection and preparation of multicenter phase 3 trial of…
- Trial name
- SENORITA2 (NCT03123042)
- Testing
- Sentinel basin dissection
- Where
- 9 sites in South Korea
- Volunteers
- 243 people
- Sponsor
- National Cancer Center, Korea
Biliary Atresia
Laparoscopic Kasai Has Similar Anesthetic Outcomes to Open Kasai
Biliary atresia (BA) is a rare biliary tree disease with a high incidence in eastern Asia. Kasai operation is a standard treatment for BA, and studies have shown that timely Kasai operation is crucial for better outcomes.
- Trial name
- NCT06163417
- Testing
- laparoscopic
- Volunteers
- 28 people
- Sponsor
- Taichung Veterans General Hospital
Thoracic Surgery, Air Leak
BioGlue or Vivostat in the Control of Air Leak in Thoracic Surgery
Following lung surgery air may continue to leak from the surface of the lung. Chest drains are placed to allow this air to be removed safely and prevent the lung from collapsing.
- Trial name
- NCT00927342
- Testing
- Vivostat, BioGlue
- Where
- United Kingdom
- Volunteers
- 103 people
- Sponsor
- Royal Brompton & Harefield NHS Foundation Trust
Major Non-cardiac Surgery
Goal Directed Hemodynamic Management and Renal Outcome After Major Non-cardiac Surgery
This study is designed to compare renal outcome of patients following major non-cardiac surgery with different perioperative hemodynamic managements: a goal directed hemodynamic management group (using PiCCO) and a control group.
- Trial name
- IROM (NCT01035541)
- Testing
- PiCCO® Monitoring
- Where
- Germany
- Volunteers
- 180 people
- Sponsor
- Technical University of Munich
Drug Use
A Randomized Comparison of Two Doses of Tranexamic Acid in Open-Heart Surgery
Perioperative bleeding during cardiac surgery is associated with a higher incidence of reoperation and blood transfusion leading to an increase in morbidity and mortality. Coagulopathy is a major cause of excessive bleeding.
- Trial name
- NCT04996368
- Testing
- Tranexamic acid injection
- Where
- Nepal
- Volunteers
- 120 people
- Sponsor
- Shahid Gangalal National Heart Centre
Childhood Germ Cell Tumor, Extragonadal Germ Cell Tumor
Combination Chemotherapy in Treating Children With Newly Diagnosed Malignant Germ Cell Tumors
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining more than one drug may kill more tumor cells.
- Trial name
- NCT00066482
- Testing
- bleomycin sulfate, filgrastim, cisplatin
- Where
- 98 sites in United States, Australia and 2 more
- Volunteers
- 19 people
- Sponsor
- Children's Oncology Group
Hearing Loss, Cochlear Implant
AB-Intra- and Post-Operative Measures of Auditory Function
The purpose of this study is to see how the inner ear responds to sound delivered to the ear canal during and after your cochlear implant surgery.
- Trial name
- AB-ECOG (NCT03685461)
- Testing
- Electrocochleography
- Where
- United States
- Volunteers
- 88 people
- Sponsor
- Medical College of Wisconsin
Coronary Arteriosclerosis
Endoscopic Vessel Harvesting During Coronary Bypass Surgery
Conventional open vein harvesting from the legs during coronary artery bypass surgery result in wound complications among 30% of the patients.
- Trial name
- NCT00235846
- Testing
- vein harvest
- Where
- Denmark
- Volunteers
- 132 people
- Sponsor
- Aalborg University Hospital
Acute Pancreatitis
A Novel Surgical Strategy to Reduce Major Complications in Patients With Necrotizing Pancreatitis
The goal of this observational study is to compare patient outcomes between the groups of patients admitted before and after the full implementation of the novel surgical strategy in patients with necrotizing pancreatitis.
- Trial name
- NCT06241586
- Testing
- The novel PMMI surgical strategy, The conventional step-up strategy
- Where
- China
- Volunteers
- 271 people
- Sponsor
- Tianjin Nankai Hospital
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