Clinical trials: conventional surgery
Inguinal Hernia Repair
Modified vs. Conventional Laparoscopic TAPP for Inguinal Hernia
This study aims to compare the outcomes of two laparoscopic techniques for repairing inguinal hernias: the modified tumescent technique (MT-TAPP) and the conventional laparoscopic transabdominal preperitoneal technique (CL-TAPP).
- Trial name
- NCT07373314
- Testing
- Modified Tumescent Laparoscopic TAPP (MT-TAPP) for the first group., Conventional Laparoscopic TAPP (CL-TAPP)
- Volunteers
- 60 people
- Sponsor
- University of Health Sciences Lahore
Breast Cancer
Multifunctional Magnetic Resonance Imaging in Predicting Breast Lesions in Women Undergoing Mastectomy for Breast Cancer
RATIONALE: Diagnostic procedures, such as multifunctional magnetic resonance imaging, may help doctors learn the extent of disease and plan the best treatment.
- Trial name
- NCT00602316
- Testing
- gadolinium-chelate, conventional surgery, magnetic resonance imaging
- Where
- United Kingdom
- Volunteers
- 20 people
- Sponsor
- Royal Marsden NHS Foundation Trust
Cervical Cancer, Cervical Dysplasia
Clinical Validation of Cervical Cancer Screening Methods
This single-institution cross-sectional non-inferiority validation study evaluates alternative techniques and tests for primary cervical cancer screening programs in Russia, particularly: local cytology staining techniques, local…
- Conditions
- Cervical Cancer, Cervical Dysplasia, Human Papilloma Virus
- Trial name
- NCT04783649
- Testing
- Papanicolaou cytological test, Local cytological test (H&E stain), Validated HPV DNA Test
- Where
- Russia
- Volunteers
- 2,500 people, healthy volunteers welcome
- Sponsor
- N.N. Petrov National Medical Research Center of Oncology
Colorectal Cancer, Gastrointestinal Dysfunction
Electroacupuncture (EA) Promotes Gastrointestinal Functional Recovery After Radical Colorectal Cancer Surgery
The goal of this clinical trial is to verify the efficacy of electroacupuncture in accelerating the recovery of gastrointestinal function after colorectal cancer surgery.
- Trial name
- NCT06128785
- Testing
- Electroacupuncture group, Conventional Treatment group
- Where
- China
- Volunteers
- 305 people
- Sponsor
- Shanghai Yueyang Integrated Medicine Hospital
Mucinous Adenocarcinoma of the Rectum, Recurrent Rectal Cancer
Phase I Study of Neoadjuvant Radiotherapy With 5-Fluorouracil for Rectal Cancer
This phase I trial studies the side effects and best dose of fluorouracil when given together with radiation therapy followed by combination chemotherapy before and after surgery in treating patients with rectal cancer that has…
- Conditions
- Mucinous Adenocarcinoma of the Rectum, Recurrent Rectal Cancer, Signet Ring Adenocarcinoma of the Rectum, Rectal Adenocarcinoma
- Trial name
- NCT02270606
- Testing
- intensity-modulated radiation therapy, fluorouracil, oxaliplatin
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- Virginia Commonwealth University
Implant Complication, Dental Implant Failed
Artificial Intelligence Assisted Socket Shield With Computer Guided Implant Placement
Aim of the current randomized clinical trial is to evaluate and compare the effectiveness of computer-guided immediate implant placement performed simultaneously with artificial intelligence assisted socket shield technique…
- Trial name
- NCT06299449
- Testing
- free-hand socket shield, AI/guided socket shield
- Where
- Egypt
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Kafrelsheikh University
Tennis Elbow
Non-Surgical Treatment Approaches in Patients With Newly Diagnosed Lateral Epicondylitis: A Randomized Clinical Trial
Lateral epicondylitis (tennis elbow) is a painful musculoskeletal condition, which is considered to be due to overuse, over-stress or over-exertion of the wrist extensors of the forearm, especially extensor carpi radialis brevi.
- Trial name
- NCT02930304
- Testing
- first physiotherapy, second physiotherapy, third physiotherapy
- Where
- Turkey (Türkiye)
- Volunteers
- 45 people
- Sponsor
- Hacettepe University
Periodontitis
Salivary Bacterial Profiles in Relation to Periodontal Treatment
The purpose of the present investigation is to record and compare bacterial compositions in subgingival plaque samples and saliva samples in subjects receiving periodontal treatment.
- Trial name
- NCT02913248
- Testing
- Conventional periodontal treatment
- Where
- Denmark
- Volunteers
- 30 people
- Sponsor
- University of Copenhagen
Dystocia
Push With Lower Uterine Segment Support
The study aims to compare maternal and early neonatal outcomes of abdominal disimpaction with lower uterine segment support in comparison to the classic "push" method for delivery of impacted fetal head during Cesarean section…
- Trial name
- PLUS (NCT02934516)
- Testing
- Cesarean section
- Volunteers
- 66 people
- Sponsor
- Assiut University
Retinal Detachment, Metamorphopsia
Effect of Type of Head Positioning on Retinal Displacement in Vitrectomy for Retinal Detachment
Patients may experience metamorphopsia, or image distortion, after having vitrectomy to repair their rhegmatogenous retinal detachments especially those with a detached macula.
- Trial name
- DIAMOND (NCT04035343)
- Testing
- Face down positioning, Supine positioning
- Where
- Canada
- Volunteers
- 324 people
- Sponsor
- Unity Health Toronto
Dental Implant Failure Nos
Dental Implants Placed by Using a Drill Guide Versus Non-guided Placement. Follow-up Study
To assess implant outcomes, both clinical and radiological, in a randomized study on guided implant placement after 3-year follow-up, compared to non-guided treatment.
- Trial name
- NCT03041584
- Testing
- Guided placement, Non-guided placement, Astra Tech TX implant
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- KU Leuven
Funnel Chest
Functional Capacity of Exercise and Lung Function in Patients Submitted Early Rehabilitation
The aim of this study was to compare the functional capacity of exercise by six-minute walk test and lung function by spirometry, before and after Nuss procedure in subjects who have undergone the early rehabiliation program with…
- Trial name
- NCT02441452
- Testing
- Early rehabilitation
- Volunteers
- 40 people
- Sponsor
- Instituto do Coracao
Missed Abortion, Early Pregnancy Failure
A Real-World Study Comparing the Efficacy of Different Treatment Regimens for Early Missed Abortion
At present, there is no unified standard for the treatment of missed abortion in clinical practice. This study intends to collect clinical data of this type of disease to compare the efficacy of different treatments, and on this…
- Trial name
- NCT07422506
- Testing
- Control group, Conventional dose of estrogen, High-dose estrogen
- Where
- China
- Volunteers
- 580 people
- Sponsor
- The Third Xiangya Hospital of Central South University
Lumbar Disc Herniations
Clinical Effects of Moxibustion Combined With Tailored Baduanjin Exercise Programs on Early Postoperative Rehabilitation in Lumbar Disc Herniation Patients Undergoing Minimally Invasive Surgery
This study is a single-center randomized controlled trial, aiming to explore the effect of moxibustion combined with the modified Baduanjin exercise regimen on the early rehabilitation of patients with lumbar disc herniation…
- Trial name
- NCT07015658
- Testing
- Baduanjin, Moxibustion, Conventional intervention
- Volunteers
- 120 people
- Sponsor
- Suyun Liu
Barlow's Disease, Prolapse; Mitral
Minimally Invasive or Conventional Edge-To-Edge Repair for Severe Mitral Regurgitation Due to Bileaflet Prolapse in Barlow's Disease: Does the Surgical Approach Have an Impact on the Long-term Results?
The study evaluates the long-term results of patients affected by bileaflet prolapse in Barlow's Disease, treated with edge-to-edge technique between 1997 and 2011.
- Trial name
- NCT04002648
- Testing
- Right minithoracotomy, Sternotomy
- Volunteers
- 208 people
- Sponsor
- Ospedale San Raffaele
Rectal Prolapse, Pelvic Organ Prolapse (POP)
RECTOSACROUTEROPEXY vs. WELLS
The goal of this clinical trial was to compare two surgical techniques in female patients with full-thickness rectal prolapse. The main questions it aimed to answer were: 1.
- Trial name
- RSUP (NCT07673406)
- Testing
- Modified rectosacrouteropexy, Wells rectopexy
- Where
- Azerbaijan
- Volunteers
- 36 people
- Sponsor
- Azerbaijan Medical University
Atelectasis
Peroperative Use of Positive End-expiratory Pressure Prevents Formation of Atelectasis as Studied by Computerised Tomography at End of Surgery
Atelectasis is common during and after general anaesthesia and a number of interventions have been suggested in order to prevent their formation.
- Trial name
- NCT02548416
- Testing
- Positive end-expiratory pressure, Control group, zero PEEP
- Where
- Sweden
- Volunteers
- 24 people
- Sponsor
- Region Västmanland
Breast Cancer
Radiation Therapy (WBI Versus PBI) in Treating Women Who Have Undergone Surgery For Ductal Carcinoma In Situ or Stage I or Stage II Breast Cancer
RATIONALE: Radiation therapy uses high-energy x-rays to kill tumor cells. Giving radiation therapy in different ways may kill any tumor cells that remain after surgery.
- Trial name
- NCT00103181
- Testing
- 3-dimensional conformal accelerated partial breast irradiation, brachytherapy, whole breast irradiation
- Where
- 387 sites in United States, Canada and 2 more
- Volunteers
- 4,216 people
- Sponsor
- NSABP Foundation Inc
Peritoneal (Metastatic) Cancer, Peritoneal Carcinomatosis
Heated Versus Aerosol-based Laparoscopic Chemotherapy for Cancer That Has Spread to the Peritoneum (Abdominal Lining)
This research study aims to improve the treatment of Peritoneal Carcinomatosis (PC), a condition where cancer spreads within the abdomen. Patients with PC often experience significant pain and nutritional problems.
- Conditions
- Peritoneal (Metastatic) Cancer, Peritoneal Carcinomatosis, Abdominal Cancer, Abdominal Cancer Patients
- Trial name
- Charlie-2 (NCT07282834)
- Testing
- Heated intra-peritoneal chemotherapy, Aerosolized intra-peritoneal chemotherapy
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Patrick Wagner, MD, FACS
Bladder Cancer
Comprehensive Geriatric Assessment for Perioperative Optimization in Cystectomy
Patients with muscle-invasive bladder cancer are often older and multimorbid, thus in an increased risk of perioperative mortality and morbidity in relation to radical cystectomy (RC).
- Trial name
- COMPETENCE (NCT05679557)
- Testing
- Perioperative geriatric assessment and intervention
- Where
- Denmark
- Volunteers
- 140 people
- Sponsor
- Aarhus University Hospital