Clinical trials: conventional surgery, completed
Glaucoma
Comparison Of Trabeculectomy Versus The Ex-PRESS Miniature Glaucoma Device In The Same Patient: A Prospective Randomized Study
the purpose of this study was to compare standard trabeculectomy to the Ex-PRESS mini glaucoma shunt implantation under a scleral flap in eyes with open-angle glaucoma.In this report, we describe the results of a prospective…
- Trial name
- XVT-USF (NCT00698438)
- Testing
- Ex-PRESS implantation, Trabeculectomy
- Where
- South Africa
- Volunteers
- 30 people
- Sponsor
- University of Witwatersrand, South Africa
Colorectal Cancer, Metastatic Cancer
Surgery With or Without Radiofrequency Ablation Followed by Irinotecan in Treating Patients With Colorectal Cancer That is Metastatic to the Liver
RATIONALE: Radiofrequency ablation uses high-frequency electric current to kill tumor cells. Combining radiofrequency ablation with surgery may kill more tumor cells.
- Trial name
- NCT00030563
- Testing
- irinotecan hydrochloride, adjuvant therapy, conventional surgery
- Where
- 3 sites in United States, Canada
- Sponsor
- University of Washington
Occlusive Dressings, Nursing
Wich is the Best Dressing in Wounds by Primary Surgery of THA and / or TKA?
Surgical wounds are covered to prevent bleeding, absorb the exudates and provide a barrier against external contamination. Currently, in Corporació PT after orthopedic surgery, traditional occlusive dressing of sterile gauze and…
- Conditions
- Occlusive Dressings, Nursing, Knee Surgery, Hip Surgery
- Trial name
- NCT03190447
- Testing
- Aquacel Surgical®, Mepilex Border post-op®, Opsite post-op visible®
- Where
- Spain
- Volunteers
- 560 people
- Sponsor
- Corporacion Parc Tauli
Constipation, Impaction, and Bowel Obstruction, Unspecified Adult Solid Tumor, Protocol Specific
S1316, Surgery or Non-Surgical Management in Treating Patients With Intra-Abdominal Cancer and Bowel Obstruction
This partially randomized clinical trial studies surgery or non-surgical management in treating patients with intra-abdominal cancer and bowel obstruction.
- Trial name
- NCT02270450
- Testing
- therapeutic conventional surgery, gastrointestinal complications management/prevention, quality-of-life assessment
- Where
- 38 sites in United States, Canada and 3 more
- Volunteers
- 221 people
- Sponsor
- SWOG Cancer Research Network
Adenomyosis
GyneFix IUD Plus LNG-IUS for Adenomyosis
Adenomyosis is a common gynecological condition that can cause menstrual pain, heavy menstrual bleeding, anemia, and reduced quality of life.
- Trial name
- GYNEFIX-AM (NCT07680985)
- Testing
- Indomethacin-GyneFix IUD Plus LNG-IUS, Ring IUD Plus LNG-IUS, LNG-IUS Alone
- Where
- China
- Volunteers
- 270 people
- Sponsor
- Wenzhou People's Hospital
Pediatric Disorder, Pneumothorax, Spontaneous
Single Site Thoracic Surgery for Pediatric Pneumothorax
Video-Assisted Thoracoscopic Surgery (VATS) has become a standard of care in adults, pediatric surgeons have been slower to undertake this approach. There are limitations for working in children.
- Conditions
- Pediatric Disorder, Pneumothorax, Spontaneous, Thoracic Diseases, Thoracic Surgery
- Trial name
- NCT05034640
- Testing
- Conventional multiport thoracoscopic surgery, Single port site thoracoscopic surgery
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- Loma Linda University
Cardiovascular Diseases, Heart Diseases
Occluded Artery Trial (OAT)
The purpose of this study is to determine whether opening an occluded infarcted artery 3-28 days after an acute myocardial infarction in high-risk asymptomatic patients reduces the composite endpoint of mortality, recurrent…
- Conditions
- Cardiovascular Diseases, Heart Diseases, Myocardial Infarction, Heart Failure, Congestive
- Trial name
- OAT (NCT00004562)
- Testing
- Beta adrenergic blockers, Platelet inhibitors, PTCA and stents
- Where
- United States
- Volunteers
- 2,201 people
- Sponsor
- NYU Langone Health
Type 2 Diabetes
The Role of Small Intestinal Endocrine Cells in Type 2 Diabetic Hyperglucagonemia
The purpose of this study is to determine whether excessive secretion of glucagon in type 2 diabetes originates from the pancreatic alpha-cells or endocrine cells in the mucosa of the small intestinal.
- Trial name
- T2DM-PC1-2 (NCT00639613)
- Testing
- Double-balloon enteroscopy, Standard meal test
- Where
- Denmark
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University Hospital, Gentofte, Copenhagen
Acute Respiratory Distress Syndrome (ARDS)
Extracorporeal Membrane Oxygenation for Severe Acute Respiratory Distress Syndrome
This international multicenter, randomized, open trial will evaluate the impact of Extracorporeal Membrane Oxygenation (ECMO), instituted early after the diagnosis of acute respiratory distress syndrome (ARDS) not evolving…
- Trial name
- EOLIA (NCT01470703)
- Testing
- ECMO (Quadrox®, Jostra®, Maquet®), conventional care
- Where
- France
- Volunteers
- 249 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Lung Cancer
Combination Chemotherapy Followed by Radiation Therapy Before Surgery in Treating Patients With Stage IIIB NSCLC
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Radiation therapy uses high energy x-rays to damage tumor cells.
- Trial name
- NCT00030810
- Testing
- Hyperfractionated, Taxotere/Cisplatin, conventional surgery
- Where
- Switzerland
- Volunteers
- 46 people
- Sponsor
- Swiss Cancer Institute
Preoperative Care, Anxiety
Perioperative Effects of Operating Room Virtual Tour
Preoperative anxiety is associated with adverse consequences such as emergence delirium, and postoperative behavioral changes. According to previous studies, providing information of anesthetic procedures helps to lessen…
- Conditions
- Preoperative Care, Anxiety, Emergence Delirium, Postoperative Complications
- Trial name
- NCT03172182
- Testing
- a 360-degree VR video tour
- Where
- South Korea
- Volunteers
- 86 people
- Sponsor
- Seoul National University Bundang Hospital
Extra-articular Distal Radius Malunions
Computer Assisted Planning of Corrective Osteotomy for Distal Radius Malunion
The investigators are comparing post-operative patient-rated functional outcome between patients who undergo corrective osteotomy for extra-articular malunited distal radius fractures with and without computer assisted…
- Trial name
- NCT01897246
- Testing
- Corrective osteotomy with computer-assisted pre-operative planning, Corrective osteotomy with conventional preoperative planning
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Christine M. Kleinert Institute for Hand and Microsurgery
Anxiety State, Parent-Child Relations
Impact of Preanesthetic Information and Behavioral Intervention Using Smartphone on Anxiety of Children
Background: Preoperative Anxiety is a negative factor in anesthetic and surgical experience. Among the strategies for reducing children's anxiety, non-pharmacological strategies are as important as the pharmacological ones, but…
- Trial name
- NCT02246062
- Testing
- info, smartphone
- Where
- Brazil
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Faculdade de Ciências Médicas da Santa Casa de São Paulo
Cataract, Astigmatism
Refractive Accuracy of Toric Intraocular Lens Implantation Using Digital Marking Compared to Conventional Marking
To evaluate the postoperative refractive accuracy and intraoperative lens rotational placement of a conventional toric intraoperative marking method compared to digital marking.
- Trial name
- NCT07176897
- Testing
- Normal Toric IOL implantation with digital marking
- Where
- 2 sites in United States
- Volunteers
- 41 people
- Sponsor
- Colvard Kandavel Eye Center
Furcation Defects, Periodontal Disease
Conventional or Minimally Invasive Surgical Technique for the Treatment of Furcation Defects Using Enamel Matrix Derivative and Anorganic Bovine Bone - a Randomized Controlled Clinical Trial.
This clinical study compared a conventional surgical technique (CST) and a minimally invasive surgical technique (MIST) in the regenerative treatment of mandibular furcation defects.
- Trial name
- NCT02102360
- Testing
- Anorganic Bovine Bone, Enamel Matrix Derivative
- Where
- Brazil
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Acute Respiratory Distress Syndrome
Effect of Low Tidal Volume Ventilation in Improving Oxygenation and Thus Reducing Acute Lung Injury in the Cardiac Surgical Patient
We propose that as low tidal volume ventilation has proven to be beneficial in patients with established ARDS it may have a role in preventing the onset of acute lung injury in the cardiac surgical population.
- Trial name
- NCT00538161
- Testing
- Ventilation strategy
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- Beth Israel Deaconess Medical Center
Adenocarcinoma of the Gastroesophageal Junction, Gastric Cancer
Fluorouracil, Cisplatin, Leucovorin Calcium, and Cetuximab in Treating Patients With Adenocarcinoma of the Stomach or Gastroesophageal Junction
RATIONALE: Drugs used in chemotherapy, such as fluorouracil, cisplatin, and leucovorin calcium, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing.
- Trial name
- NCT01360086
- Testing
- cetuximab, cisplatin, fluorouracil
- Where
- 2 sites in France
- Volunteers
- 65 people
- Sponsor
- Federation Francophone de Cancerologie Digestive
Maxillary Defect Reconstruction, Atrophic Edentulous Maxilla
Evaluation of Accuracy of Three-Dimensionally Guided Zygomatic Implant Installation
This study was conducted at the Department of Oral and Maxillofacial Surgery, Faculty of Dentistry, Tanta University. A prospective non-controlled clinical study was performed on ten patients with compromised zygomaticomaxillary…
- Trial name
- NCT07463469
- Testing
- zygomatic implant installation using custamized bone supported surgical guide
- Where
- Egypt
- Volunteers
- 10 people
- Sponsor
- Tanta University
Esophageal Cancer
Radiotherapy,Chemotherapy,Before and After Surgery in Advanced Esophageal or Gastroesophageal Junction Cancer
RATIONALE: Radiation therapy uses high-energy x-rays to kill tumor cells. Drugs used in chemotherapy, such as cisplatin and fluorouracil, work in different ways to stop the growth of tumor cells, either by killing the cells or by…
- Trial name
- NCT00258323
- Testing
- cisplatin, fluorouracil, Iressa
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Case Comprehensive Cancer Center
Surgical Technical Skill, Technical Errors in Surgery
Comprehensive Surgical Coaching
Simulation in surgical skills training is widely accepted as a necessary step to improve surgical training outside the operating room. Simulation predominately focuses on teaching a specific task or procedure.
- Trial name
- NCT01875679
- Testing
- Comprehensive Surgical Coaching, Conventional Surgical Training
- Where
- Canada
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Unity Health Toronto
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