Clinical trials: conventional surgery, completed
Brain and Central Nervous System Tumors
Immunotoxin Therapy Before and After Surgery in Treating Patients With Recurrent Malignant Glioma
RATIONALE: Immunotoxins can locate tumor cells and kill them without harming normal cells. Immunotoxin therapy may be effective in treating malignant glioma.
- Trial name
- NCT00036972
- Testing
- cintredekin besudotox, adjuvant therapy, conventional surgery
- Where
- United States
- Sponsor
- Memorial Sloan Kettering Cancer Center
Laparoscopic Hysterectomy
Endoscopic Tissue Cutting and Abdominal Extraction Device vs. Conventional Cold Scalpel
The aim of the study is to compare the surgical tissue removal success of the endoscopic tissue cutting device, which was designed by the conductor and developed with the support of TUBITAK-1512 project and for which Turkish and…
- Trial name
- SOLENDO-1 (NCT07226375)
- Testing
- Vaginal tissue morcellation with extraction device, Vaginal tissue morcellation with scalpel
- Where
- Turkey (Türkiye)
- Volunteers
- 84 people
- Sponsor
- Ege University
Mandibular Fractures
Comparison of Operating Room Time Length With the Use of Virtual Surgical Planning Versus Conventional Treatment of Mandible Fractures
The purpose of this trial is to compare operating room time between conventional treatment techniques [without Virtual surgical Planning (VSP)] versus treatment with use of Virtual surgical Planning (VSP) in patients that undergo…
- Trial name
- NCT04283981
- Testing
- Control group without use of VSP, Treatment Group with use of VSP
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- The University of Texas Health Science Center, Houston
Hypocalcemia
Parathyroid Autofluorescence Visualization in Thyroid Surgery: Impact on Postoperative Hypocalcemia
This Multicenter, Randomized Controlled Trial evaluates the clinical impact of parathyroid autofluorescence visualization using near infrared light (NIR) during total thyroidectomy (TT).
- Trial name
- NCT02892253
- Testing
- Near Infrared Camera (NIR)
- Where
- 3 sites in France
- Volunteers
- 241 people
- Sponsor
- Hôpital Européen Marseille
Post-Op Complication
Delayed Rewarming for Neuroprotection in Infants Following Cardiopulmonary Bypass Surgery
This is an unblinded, single center, randomized study of infants with congenital heart disease undergoing cardiopulmonary bypass surgery, randomized to either the delayed rewarming intervention or to the standard of care (strict…
- Trial name
- NCT03036072
- Testing
- Strict normothermia, Delayed Rewarming
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Alexa Craig
Metastatic Cancer, Sarcoma
Inhaled Sargramostim in Treating Patients With First Pulmonary (Lung) Recurrence of Osteosarcoma
RATIONALE: Inhaling aerosolized sargramostim before and after surgery may interfere with the growth of tumor cells and shrink the tumor so that it can be removed during surgery.
- Trial name
- NCT00066365
- Testing
- sargramostim, conventional surgery
- Where
- 93 sites in United States, Australia and 2 more
- Volunteers
- 49 people
- Sponsor
- Children's Oncology Group
Pain, Postoperative
Sublingual Sufentanil Tablet System (SSTS) Versus Intravenous Patient Controlled Analgesia After Back Surgery.
In this study, numeric rating scale (NRS) and side effects are measured after usage of a sublingual sufentanil tablet system (SSTS) in comparison to intravenous patient controlled analgesia (PCIA).
- Trial name
- NCT03036514
- Testing
- Sublingual sufentanil tablet system, Patient-controlled intravenous analgesia
- Where
- Belgium
- Volunteers
- 27 people
- Sponsor
- University Hospital, Antwerp
Periodontitis, Periodontal Intrabony Defects
Impact of Platelet-Rich Fibrin on Periodontal Tissue Regeneration
The purpose of this research is to assess the efficacy of Platelet-Rich Fibrin (PRF) in the regeneration of periodontal tissues in patients suffering from periodontal disease.
- Trial name
- NCT07395726
- Testing
- Open Flap Debridement, Platelet-Rich Fibrin with Open Flap Debridement
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- Armed Forces Institute of Dentistry, Pakistan
Development of Pulmonary Dysfunction Following Open Abdominal Surgery
Protective Variable Ventilation for Open Abdominal Surgery
Variable ventilation has been shown to improve lung function and reduce lung damage as well as inflammation in different models of the acute respiratory distress syndrome. Also, variable ventilation is able to recruit lungs.
- Trial name
- PROVAR (NCT01683578)
- Testing
- Variable Ventilation
- Where
- Germany
- Volunteers
- 50 people
- Sponsor
- Technische Universität Dresden
Brain and Central Nervous System Tumors
Radiolabeled Monoclonal Antibody Therapy in Treating Patients With Primary Brain Tumors
RATIONALE: Monoclonal antibodies can locate tumor cells and deliver radioactive tumor-killing substances such as radioactive iodine to them without harming normal cells.
- Trial name
- NCT00003478
- Testing
- conventional surgery, iodine I 131 monoclonal antibody 81C6, radiation therapy
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Duke University
Stress Disorders, Post-Traumatic, Sleep Initiation and Maintenance Disorders
Examining the Effect of Acupuncture on Sleep Difficulties Related to Post Traumatic Stress Disorder
The purpose of this study was to examine if group ear acupuncture improves Post-Traumatic Stress Disorder sleep difficulties among veterans who participated in Operations Enduring Freedom and Iraqi Freedom.
- Trial name
- NCT00868517
- Testing
- True group auricular acupuncture, Wait-List Control Group
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- US Department of Veterans Affairs
Massage, Sleep Quality
Shoulder Massage After Cholecystectomy
Purpose The aim of this study is to determine the effect of shoulder massage administered to patients after laparoscopic cholecystectomy on pain and sleep quality. Design The study was designed as a randomized controlled trial.
- Conditions
- Massage, Sleep Quality, Laparoscopic Cholecystectomy, Shoulder Pain
- Trial name
- SMALC (NCT06480149)
- Testing
- SMALC, no application
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Maltepe University
Pulmonary Disease
High Flow vs Conventional Oxygen in Head and Neck Surgery
Patients undergoing major head and neck surgery are at risk for postoperative pulmonary complications. The goal of this randomized clinical trial is to evaluate the effectiveness of high flow heated humidified oxygen at…
- Trial name
- NCT05362526
- Testing
- High flow humidification, Conventional cool mist aerosol humidification
- Where
- United States
- Volunteers
- 56 people
- Sponsor
- University of Florida
Surgery for Sacral Nerve Neurostimulation, Surgery for Urinary Artificial Sphincter
Medico-economical Evaluation of Patient-hotel in Urology
This is a medico-economic study of outpatient surgery paired with a night stay in a patient-hotel, compared with a conventional hospitalization for three types of urological surgeries.
- Conditions
- Surgery for Sacral Nerve Neurostimulation, Surgery for Urinary Artificial Sphincter, Surgery for Prosthetic Penile Implant
- Trial name
- HOTELAMBU (NCT02890017)
- Testing
- postoperative hotel, conventional hospitalization
- Where
- France
- Volunteers
- 10 people
- Sponsor
- Hospices Civils de Lyon
Tennis Elbow
Non-Surgical Treatment Approaches in Patients With Newly Diagnosed Lateral Epicondylitis: A Randomized Clinical Trial
Lateral epicondylitis (tennis elbow) is a painful musculoskeletal condition, which is considered to be due to overuse, over-stress or over-exertion of the wrist extensors of the forearm, especially extensor carpi radialis brevi.
- Trial name
- NCT02930304
- Testing
- first physiotherapy, second physiotherapy, third physiotherapy
- Where
- Turkey (Türkiye)
- Volunteers
- 45 people
- Sponsor
- Hacettepe University
Valve Heart Disease, Awakening Early
Prospective Evaluation of Volatile Sedation After Heart Valve Surgery
Cardiac surgery is a complex operative procedure with a substantial risk of postoperative complications, so that patients undergoing valve surgery are usually transferred to the intensive care unit postoperatively.
- Trial name
- NCT04958668
- Testing
- Post-operative intensive care using volatile sedation
- Where
- Germany
- Volunteers
- 100 people
- Sponsor
- Goethe University
Acute Abdomen
Different Fluidic Strategy in Patients With Acute Abdomen : The Sure Volume
Acute abdomen is the clinical manifestation of irritation of the peritoneum, due to intra-abdominal generalized infection. With the exception of the primary ones which are the result of a bacterial translocation from the…
- Trial name
- NCT01911702
- Testing
- Standard fluidic resuscitation., Volemic small treatment
- Volunteers
- 99 people
- Sponsor
- Azienda Ospedaliero-Universitaria di Modena
Stage 0 Breast Cancer AJCC v6 and v7, Stage I Breast Cancer AJCC v7
Alternative Dosing of Exemestane Before Surgery in Treating Postmenopausal Patients With Stage 0-II Estrogen Positive Breast Cancer
This phase IIb trial studies how well alternative dosing of exemestane before surgery works in treating in postmenopausal patients with stage 0-II estrogen positive breast cancer.
- Conditions
- Stage 0 Breast Cancer AJCC v6 and v7, Stage I Breast Cancer AJCC v7, Stage IA Breast Cancer AJCC v7, Stage IB Breast Cancer AJCC v7
- Trial name
- NCT02598557
- Testing
- Exemestane, Laboratory Biomarker Analysis, Pharmacological Study
- Where
- 5 sites in United States, Italy
- Volunteers
- 180 people
- Sponsor
- National Cancer Institute (NCI)
Endometrial Cancer, Endometrial Neoplasms
Real-time Lymphatic Channel Visualization Improves Bilateral Sentinel Lymph Node Detection in Endometrial Cancer
Endometrial cancer is the most common malignancy of the female genital tract. Standard treatment for early-stage disease includes hysterectomy, bilateral salpingo-oophorectomy, and lymph node assessment.
- Conditions
- Endometrial Cancer, Endometrial Neoplasms, Sentinel Lymph Node Biopsy (SLNB)
- Trial name
- NCT05191212
- Testing
- indocyanine green
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Bakirkoy Dr. Sadi Konuk Research and Training Hospital
Rotator Cuff Tear
Effects of Kinesiotaping on Muscular Activity, Mobility, Strength and Pain After Rotator Cuff Surgery
Kinesiotape (KT) is widely used in musculoskeletal rehabilitation as an adjuvant to treatment but minimal evidence supports its use.
- Trial name
- NCT03379636
- Testing
- kinesiotape
- Volunteers
- 39 people
- Sponsor
- Clinique Romande de Readaptation
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