Clinical trials: flow cytometry, completed
Benign Prostatic Hyperplasia, Prostate Carcinoma
Human Prostate Tissue Model to Maintain and Study Prostate Cancer Stem Cells
This pilot research trial studies the use of a human prostate tissue model to maintain and study prostate cancer stem cells. A human prostate tissue model uses leftover tissue that was removed during surgery from patients with…
- Trial name
- NCT02425800
- Testing
- Cytology Specimen Collection Procedure, Laboratory Biomarker Analysis
- Where
- 2 sites in United States
- Volunteers
- 43 people
- Sponsor
- Wake Forest University Health Sciences
Astrocytoma, Glioma
Qualitative, Qualitative, and Functional Studies Over the First Year in Measuring Immune System Response During the First Year of Therapy in Patients With Brain Tumors
This research trial studies qualitative, qualitative, and functional studies over the first year in measuring immune system response in patients with brain tumors.
- Conditions
- Astrocytoma, Glioma, Oligodendroglioma
- Trial name
- NCT02747407
- Testing
- Hepatitis A Vaccine, Laboratory Biomarker Analysis, Tetanus Toxoid Vaccine
- Where
- United States
- Volunteers
- 55 people
- Sponsor
- Wake Forest University Health Sciences
Leukemia
Comparison of Laboratory Test Results of Minimal-Residual Disease in Samples From Patients With Acute Myeloid Leukemia
RATIONALE: Diagnostic procedures that find residual disease may help predict if the disease will come back in patients diagnosed with acute myeloid leukemia.
- Trial name
- NCT01498302
- Testing
- diagnostic laboratory biomarker analysis, flow cytometry
- Volunteers
- 10 people
- Sponsor
- Children's Oncology Group
Weight Loss, Exercise
Effects of Exercise and Short Term Rapid Weight Loss on Whole Blood Cells and Lymphocyte Subsets in Highly Trained National Level Wrestlers
Wrestling is a weight-classified sport in which athletes frequently apply rapid weight loss (RWL) strategies prior to competition.
- Trial name
- EX-RWL-Lymphoc (NCT07567937)
- Testing
- Exercise, Rapid Weight Loss
- Where
- Turkey (Türkiye)
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- Ankara Yildirim Beyazıt University
Drug-Induced Liver Injury
Immune Responses in Hepatocellular Carcinoma Patients After Treatment With Direct Acting Antiviral Drugs
Case control Study to assess the difference of immune cell responses between patients with chronic HCV- related liver cirrhosis who develop HCC after treatment with DAAs and those who do not develop HCC
- Trial name
- NCT03602703
- Testing
- Flow cytometry and Western Blot analysis
- Where
- Egypt
- Volunteers
- 42 people
- Sponsor
- Assiut University
Acute T-Cell Leukemia-Lymphoma
Campath-1H for Treating Adult T-Cell Leukemia/Lymphoma
This study will examine the safety and effectiveness of Alemtuzumab (Campath-1H) for treating patients with adult T-cell leukemia/lymphoma (ATL).
- Trial name
- NCT00061048
- Testing
- Alemtuzumab
- Where
- United States
- Volunteers
- 29 people
- Sponsor
- National Cancer Institute (NCI)
Recurrent Melanoma, Stage IV Melanoma
Individualized Temozolomide in Treating Patients With Stage IV Melanoma That Cannot Be Removed By Surgery
This clinical trial studies individualized temozolomide (TMZ) in treating patients with stage IV melanoma that cannot be removed by surgery.
- Trial name
- NCT01328535
- Testing
- temozolomide, flow cytometry, staining method
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Mayo Clinic
Healthy Volunteers
Analyzes of Nasal Tissue-resident Memory Immune Cells and Peripheral Memory Cells Able to Migrate to Airway Tissues (MUCOVAC)
Clinical evaluation of vaccines against respiratory viruses is currently based on the analysis of systemic immune responses, whereas respiratory immunity is the first line of defense against respiratory pathogens.
- Trial name
- MUCOVAC (NCT06469359)
- Testing
- Nasal tissue-resident memory T and B cells, Nasal fluid sampling, Saliva sampling
- Where
- France
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Cardiotoxicity, Cardiovascular Disease
Effect of Anthracyclines and Cyclophosphamide on Cardiovascular Responses
The present study aims to investigate the chronic effect of treatment with doxorubicin and cyclophosphamide on neurovascular control and blood pressure in women undergoing adjuvant treatment for breast cancer.
- Conditions
- Cardiotoxicity, Cardiovascular Disease, Neurovascular Disorder, Endothelial Disfunction
- Trial name
- NCT04568161
- Testing
- Physical Characteristics, Muscular Sympathetic Nervous Activity, Cardiac Function
- Where
- Brazil
- Volunteers
- 15 people
- Sponsor
- University of Sao Paulo General Hospital
Colorectal Cancer
Intraoperative Flow Cytometry In Colorectal Cancer
This study was designed to investigate the efficacy of flow cytometry to accurately identify between normal and cancer cells in colon epithelium in humans diagnosed with colorectal cancer.
- Trial name
- NCT05261542
- Testing
- flow cytometry
- Where
- Greece
- Volunteers
- 106 people
- Sponsor
- University Hospital, Ioannina
Acute Lymphoblastic Leukemia (ALL)
Potential Role of CD9 and Implication of Motility Process in Pathogenesis of TEL/ALM1-positive ALL Relapses (LAL TEL/ALM1 and CD9).
Down regulation of CD9 in TEL/AML1-positive ALL is addressed in motility assays to explore its role in B-ALL pathogenesis and its potential implication in relapses (and prognosis).
- Trial name
- LAL TEL/ALM1 (NCT01282593)
- Testing
- Impact of CD9 expression level on motility assays, Post-transcriptional regulation of CD9
- Where
- France
- Volunteers
- 51 people
- Sponsor
- Rennes University Hospital
Covid19, Acute Respiratory Distress Syndrome
Clinical Features of COVID-19 Patients
The data were retrospectively collected during the first and the second wave of epidemic in COVID-19 patients with Severe Acute Respiratory Syndrome Coronavirus 2, at the moment of intensive care unit admission and during the in…
- Conditions
- Covid19, Acute Respiratory Distress Syndrome, Ventilatory Failure
- Trial name
- NCT04815304
- Testing
- peripheral lymphocytes subsets
- Where
- Italy
- Volunteers
- 200 people
- Sponsor
- San Salvatore Hospital of L'Aquila
HIV Infections, HIV Seronegativity
A Blood Test to Look at Cells of the Immune System in Healthy Children
The purpose of this study is to learn more about some of the immune cells in the blood (CD4 cells, for example) of healthy children in order to better understand the differences in the blood cells of children infected with HIV.
- Trial name
- NCT00001109
- Where
- 45 sites in United States, Puerto Rico
- Volunteers
- 630 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Brain and Central Nervous System Tumors
Bevacizumab and Sorafenib in Treating Patients With Recurrent Glioblastoma Multiforme
RATIONALE: Monoclonal antibodies, such as bevacizumab, can block tumor growth in different ways. Some block the ability of tumor cells to grow and spread.
- Trial name
- NCT00621686
- Testing
- bevacizumab, sorafenib tosylate
- Where
- 204 sites in United States
- Volunteers
- 54 people
- Sponsor
- Alliance for Clinical Trials in Oncology
Lymphoma
Clinical Evaluations and Laboratory Studies to Study the Disease Course in Patients With Cutaneous T-Cell Lymphoma
RATIONALE: Gathering information about patients with cutaneous T-cell lymphoma over time may help doctors learn more about the disease.
- Trial name
- NCT00430053
- Testing
- gene rearrangement analysis, polymerase chain reaction, proteomic profiling
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- National Institutes of Health Clinical Center (CC)
Cancer
Vaccine Therapy in Treating Patients Who Have Undergone a Donor Stem Cell Transplant and Have Cytomegalovirus Infection That Has Not Responded to Therapy
RATIONALE: Vaccines may help the body build an effective immune response to kill cytomegalovirus infections. PURPOSE: This phase I trial is studying the side effects and best dose of vaccine therapy in treating patients who have…
- Trial name
- NCT00509691
- Testing
- cytomegalovirus pp65-specific cytotoxic T lymphocytes, polymerase chain reaction, diagnostic laboratory biomarker analysis
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Louisville
Shock, Cardiogenic, Extra-Corporeal-Life-Support ( ECLS)
Impact of Adrenoreceptor Expressions on Inflammatory Pattern in Refractory Cardiogenic Shock Under VA ECMO
Refractory cardiogenic shock is characterized by a decreased in cardiac output with hypo-responsiveness to increasing doses of catecholamines resulting in a profound tissular ischemia.
- Conditions
- Shock, Cardiogenic, Extra-Corporeal-Life-Support ( ECLS), Autonomic Nervous System Diseases, Inflammation
- Trial name
- ADRECMO (NCT03327493)
- Testing
- Biological
- Where
- France
- Volunteers
- 48 people
- Sponsor
- Central Hospital, Nancy, France
Neoplastic Cells, Circulating
The Detection of Circulating Tumor Cells (CTCs) in Patients With Lung Cancer Undergoing Cryosurgery Combined With DC-CIK Treatment
Circulating tumor cells (CTCs) have the potential to provide a surrogate for'real-time biopsy' of tumor biological activity. Enumeration and molecular characterization of CTCs in lung cancer could play an important role in…
- Trial name
- NCT02412384
- Testing
- Flow cytometry (FCM), RT-PCR
- Where
- China
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Fuda Cancer Hospital, Guangzhou
Leukemia, Myelodysplastic Syndromes
Evaluating Cell Damage in Patients With Acute Myeloid Leukemia, Myelodysplastic Syndromes, or Fanconi Anemia; in Patients Who Were Exposed to Alkylating Agents; and in Healthy Volunteers
RATIONALE: Studying samples of bone marrow from patients with cancer and from healthy volunteers in the laboratory may help doctors learn more about changes that occur in bone marrow stromal (connective tissue) cells.
- Trial name
- NCT00899795
- Testing
- cytogenetic analysis, fluorescence in situ hybridization, flow cytometry
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- OHSU Knight Cancer Institute
Myeloid Proliferations Associated With Down Syndrome
Study of Blood Samples From Newborns With Down Syndrome
This research study is looking at blood samples from newborns with Down syndrome. Studying the genes expressed in samples of blood from patients with Down syndrome may help doctors identify biomarkers related to cancer.
- Trial name
- NCT00959283
- Testing
- Diagnostic Laboratory Biomarker Analysis, Pharmacological Study
- Where
- 189 sites in United States, Australia and 2 more
- Volunteers
- 180 people
- Sponsor
- Children's Oncology Group