Clinical trials: tDCS, completed
Stroke, Paresis
Hemiparetic Arm Robotic Mobilization With Non Invasive Electrical Stimulation
The two cerebral hemispheres find themselves in a state of balanced mutual inhibition. A stroke with involvement of motor function leads to a reduced excitability in affected hemisphere M1 and to an increased excitability of…
- Conditions
- Stroke, Paresis, Upper Extremity Paralysis
- Trial name
- hARMonies (NCT03026712)
- Testing
- Real dual tDCS + Robotic Arm Therapy
- Where
- 2 sites in Italy
- Volunteers
- 80 people
- Sponsor
- I.R.C.C.S. Fondazione Santa Lucia
Infantile Hemiplegia
Transcranial Direct Current Stimulation for Attention Deficit
Infantile hemiplegia due to brain injury is associated with poor attention. Left-sided infantile hemiplegia affects the learning and acquisition of new skills.
- Trial name
- NCT04278430
- Testing
- transcranial direct current stimulation
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Majmaah University
Hemispatial Neglect
Sleep as a Model to Understand and Manipulate Cortical Activity in Order to Promote Functional Recovery After Stroke
Brain functions are supported by multiple cell types, including neuronal and non-neuronal cells that are connected into complex networks.
- Trial name
- SSS (NCT03090711)
- Testing
- Transcranial Magnetic Stimulation (TMS), Transcranial Alternating Current Stimulation (tACS)
- Where
- Switzerland
- Volunteers
- 21 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Cerebral Palsy
Integrated Management Enhances Functional Gains in Children With Cerebral Palsy Treated by BoNT-A
Evidence from literature support the use of Botulinum toxin A (BoNT-A) for upper limb spasticity management in children with cerebral palsy (CP).
- Trial name
- NCT03302871
- Testing
- Botulinum toxin type A, transcranial direct current stimulation, hybrid training model of CIMT and BIT
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Kocaeli University
Chronic Stroke
Brain Stimulation and Robotics in Chronic Stroke Motor Recovery
Motor skill training and transcranial direct current stimulation (tDCS) have separately been shown to alter cortical excitability and enhance motor function in humans.
- Trial name
- NCT03562663
- Testing
- Transcranial direct current stimulation, Upper extremity robotics
- Volunteers
- 82 people
- Sponsor
- Burke Medical Research Institute
Physiology
Physiopathology of Lower Cortical Activation in COPD Patients: Contribution of Cortical Neuromodulation
Patients with COPD have lower cortical activation and higher cortical inhibitory levels. The purpose of this study is to test the reversibility the lower cortical activation by counterbalancing the increased cortical inhibitory…
- Trial name
- NCT03368703
- Testing
- Anodal transcranial direct-current-stimulation
- Where
- France
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- 5 Santé
Tinnitus, Subjective
Consecutive Dual-Session tDCS in Chronic Subjective Severe to Catastrophic Tinnitus With Normal Hearing
We aimed to analyze the effect of continuous dual session tDCS in patients with severe chronic subjective tinnitus without any evidence of hearing loss in terms of relief of tinnitus perception, distress, and loudness.
- Trial name
- NCT06423742
- Testing
- Transcranial direct current stimulation
- Where
- South Korea
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Dongtan Sacred Heart Hospital
Stroke, Upper Extremity Paresis
NIBS With mCIMT for Motor and Functional Upper Limb Recovery in Stroke Patients.
Stroke is one of the leading causes of serious long-term impairment. According to the estimates, 12,500 people suffer a new or recurrent ischemic stroke in Chile annually, which shows the magnitude of the problem.
- Conditions
- Stroke, Upper Extremity Paresis, Electric Stimulation, Occupational Therapy
- Trial name
- NCT03452254
- Testing
- Active Bihemispheric Transcranial direct current Stimulation, Modified Constraint Induced Movement Therapy
- Where
- 2 sites in Chile
- Volunteers
- 70 people
- Sponsor
- University of Chile
Transcranial Direct Current Stimulation
Neurophysiological and Functional Mechanisms of Motor Control and Learning
Noninvasive stimulation of the central nervous system, including transcranial magnetic stimulation (TMS) and transcranial direct current stimulation (tDCS), has been increasingly used in the investigation of cortical plasticity.
- Trial name
- NCT03190590
- Testing
- tDCS-NeuroConn., TMS - Magstim.
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Major Depressive Disorder
Maintenance of Response After rTMS for Depression Using tDCS
This is a double-blind, multi-site, randomized controlled trial (RCT) that will recruit 200 participants.The purpose of the RCT will be to evaluate the efficacy of transcranial direct current stimulation (tDCS) in combination…
- Trial name
- START (NCT03708159)
- Testing
- active tDCS + mindfulness meditation
- Where
- 2 sites in Canada
- Volunteers
- 68 people
- Sponsor
- Centre for Addiction and Mental Health
Vegetative State, Minimally Conscious State
Fronto-parietal tDCS in Severely Brain Injured Patients With Disorders of Consciousness
Previous studies showed that anodal transcranial direct current stimulation (tDCS) transiently improves performance of memory and attention.
- Conditions
- Vegetative State, Minimally Conscious State, Disorders of Consciousness
- Trial name
- NCT02626403
- Testing
- Anodal tDCS
- Where
- Belgium
- Volunteers
- 46 people
- Sponsor
- University of Liege
Rumination
Effects of tDCS Combined With VR on Anxious Ruminations in Healthy Subjects With a Vulnerability to Rumination
This study proposes: to evaluate 1) whether the combination of virtual reality (VR) and active tDCS provides better rumination attenuation than the combination of VR and tDCS placebo 2) the acceptability and experiential…
- Trial name
- REVISTIM-XX (NCT03915041)
- Testing
- VR + active brain stimulation
- Where
- France
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Nantes University Hospital
Treatment Resistant Depression, Major Depressive Disorder
Dose-Optimized and Spaced Transcranial Direct Current Stimulation for Treatment-Resistant Depression
This study aims to evaluate the feasibility, safety, and tolerability of an innovative approach to treating Major Depressive Disorder (MDD), particularly in cases where patients have not responded well to traditional therapies.
- Trial name
- DOS (NCT06730841)
- Testing
- Dose-Optimized and Spaced Transcranial Direct Current Stimulation, Spaced Transcranial Direct Current Stimulation
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- University of California, San Diego
Fibromyalgia
Home-based Transcranial Direct Current Stimulation in Fibromyalgia Patients
In this phase II, randomized, double-blind clinical trial, the investigators intended to evaluate the home-based effect of transcranial direct current stimulation (tDCS) in patients with fibromyalgia.
- Trial name
- NCT02652988
- Testing
- Active-tDCS
- Where
- 2 sites in Brazil
- Volunteers
- 20 people
- Sponsor
- Wolnei Caumo
Osteo Arthritis Knee
Home-based tDCS and Mindfulness-based Meditation for Self-management of Clinical Pain and Symptoms
This clinical trial aims to evaluate whether a 2 week regimen of transcranial direct current stimulation (tDCS) paired with mindfulness-based meditation (MBM) can improve pain modulation, reduce clinical pain, and alleviate…
- Trial name
- NCT04375072
- Testing
- active tDCS paired with active MBM
- Where
- United States
- Volunteers
- 208 people
- Sponsor
- University of Arizona
Healthy
4 mA tDCS, Estrogen, and Leg Muscle Fatigability
The majority of transcranial direct current stimulation (tDCS) studies have failed to consider sex as a modulating factor. This neglect may partly account for the high inter-subject variability bemoaned by many tDCS investigators…
- Trial name
- NCT04471805
- Testing
- Transcranial direct current stimulation 4 mA
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Iowa
Stroke
Study to Enhance Motor Acute Recovery With Intensive Training After Stroke
Stroke often results in limitation of arm movements, from which many people do not fully recover. We believe that early and intensive therapy is important to enhance recovery of arm movements after stroke.
- Trial name
- SMARTS2 (NCT02292251)
- Testing
- Device-assisted therapy, Therapy-based occupational therapy
- Where
- 3 sites in United States, Switzerland
- Volunteers
- 32 people
- Sponsor
- Johns Hopkins University
Healthy Older Adults
tDCS Effects on Associative Learning in Older Adults of Working Age
The aim of this study is to investigate whether a tDCS-accompanied training of audio-visual associative memory leads to a performance improvement in healthy older individuals.
- Trial name
- TRAINSTIM2 (NCT02795702)
- Testing
- tDCS, training
- Where
- Germany
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Charite University, Berlin, Germany
Schizophrenic Patients
Effects of tDCS Combined With Retrieval Practice on Semantic Memory in Patients With Schizophrenia
The semantic processing deficit stands as a central feature of cognitive abnormalities in schizophrenia. Both transcranial direct current stimulation (tDCS) and retrieval practice have been demonstrated as external techniques…
- Trial name
- NCT06538259
- Testing
- Transcranial direct current stimulation (tDCS)-anodal group
- Where
- China
- Volunteers
- 52 people
- Sponsor
- Northeast Normal University
Auditory Hallucination, Schizophrenia
Transcranial Direct-current Stimulation (tDCS) in Treatment Refractory Auditory Hallucinations
This is a 4 week therapeutic pilot study with a 4 week follow-up period involving inpatients with treatment resistant DSM-IV schizophrenia or schizoaffective disorder diagnosis.
- Trial name
- tDCS (NCT03485131)
- Testing
- Transcranial direct-current stimulation (tDCS)
- Where
- United States
- Volunteers
- 27 people
- Sponsor
- Manhattan Psychiatric Center