Clinical trials: sponsored by Aalborg University Hospital
Type 2 Diabetes Treated With Insulin
The Intelligent Diabetes TelemonitoRing Using Decision Support to Treat Patients on Insulin Therapy
The trial is an open-label, randomized controlled trial. Patients with T2D on insulin therapy will be randomized to an intelligent telemonitoring group (intervention), a telemonitoring group (control), and a usual care group…
- Trial name
- DiaTRUST (NCT06185296)
- Testing
- Intelligent telemonitoring, Telemonitoring
- Where
- Denmark
- Volunteers
- 51 people
- Sponsor
- Aalborg University Hospital
Gastric Cancer, Gastro Esophageal Junctional Cancer
[68Ga]Ga-FAPI PET/CT in Gastric and Gastroesophageal Junctional Cancer
Twenty (n=20) patients with gastric cancer or gastro-esophageal junctional cancer will undergo FAPI PET/CTs in addition to routing diagnostic workup (including FDG PET/CT) at primary staging and restaging.
- Conditions
- Gastric Cancer, Gastro Esophageal Junctional Cancer, Cancer
- Trial name
- NCT05898854
- Testing
- 68Ga-FAPi-46
- Where
- Denmark
- Volunteers
- 20 people
- Sponsor
- Aalborg University Hospital
Depressive Disorder, Depression - Major Depressive Disorder
Improving Treatment for Depression in General Practice Using a Step-by-Step Care Plan.
The goal of this clinical trial is to compare three different treatments for depression in patients with moderate depression in General Practice, aged 18-65 years.
- Conditions
- Depressive Disorder, Depression - Major Depressive Disorder, Depressive Disorder, Major Depressive Disorder, Depressive Disorders
- Trial name
- ODEGA (NCT07263321)
- Testing
- Algorithm-Based Treatment, Treatment as usual (TAU)
- Where
- Denmark
- Volunteers
- 171 people
- Sponsor
- Aalborg University Hospital
Alzheimer Disease
Frailty Outcomes And Risk With Alzheimer's Related Dementia
The primary aim of this study is to investigate the association between frailty as defined by the Fried Frailty Phenotype and risk of functional decline in patients with Alzheimer's dementia.
- Trial name
- FORWARD (NCT06570109)
- Testing
- Frailty
- Where
- Denmark
- Volunteers
- 130 people
- Sponsor
- Aalborg University Hospital
Chronic Subdural Hematoma, Surgical Procedures, Operative
A National Study Examining the Most Effective Drainage Method After Burr Hole Evacuation of Chronic Subdural Hematoma
Chronic subdural hematoma (CSDH) is a common disease. The main treatment is neurosurgical evacuation and subsequent hematoma drainage.
- Conditions
- Chronic Subdural Hematoma, Surgical Procedures, Operative, Recurrence, Mortality
- Trial name
- SUPERDURA (NCT06621407)
- Testing
- 24 hours active subperiostal drainage, 24 hours passive subdural drainage
- Where
- 4 sites in Denmark
- Volunteers
- 354 people
- Sponsor
- Aalborg University Hospital
Habitual Abortion, Recurrent Pregnancy Loss
Intravenous Immunoglobulin and Prednisolone for RPL After ART.
Recurrent pregnancy loss (RPL) affects around 5 % of women in reproductive age. The underlying cause of RPL is most often unknown, probably multifactorial, and no treatment with documented effect on chance of live birth exists.
- Conditions
- Habitual Abortion, Recurrent Pregnancy Loss, Fertility Disorders, Miscarriage
- Trial name
- RPL (NCT04701034)
- Testing
- Human Intravenous Immunoglobulins, (Privigen (R), CLS Behring), Prednisolone Tablets, Human Albumin Solution
- Where
- Denmark
- Volunteers
- 80 people
- Sponsor
- Aalborg University Hospital
Healthy
Distribution of Immune Cells Subsets in Healthy Females
This study aims to evaluate the distribution of different lymphocyte subsets and other immune biomarkers in peripheral blood in healthy Danish females of reproductive age and to make a research biobank for future research.
- Trial name
- NCT05609799
- Testing
- Blood sample
- Where
- Denmark
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Aalborg University Hospital
Mannose-Binding Lectin Deficiency, Recurrent Pregnancy Loss
Association Between Plasma Level of Mannose Binding Lectin and Human Reproduction
A low plasma level of mannose binding lectin (p-MBL) is associated with unexplained recurrent pregnancy loss (RPL), but it is not investigated if it is associated with unexplained reproductive failure in general, including…
- Conditions
- Mannose-Binding Lectin Deficiency, Recurrent Pregnancy Loss, Recurrent Implantation Failure, Infertility
- Trial name
- NCT05169541
- Where
- Denmark
- Volunteers
- 500 people
- Sponsor
- Aalborg University Hospital
Hearing Loss, Sensorineural, Hearing Loss, Bilateral
Characterisation of Low Frequency Hearing and Vestibular Function in Patients Undergoing Cochlear Implantation
The study will follow a cohort of CI-candidates becoming CI-user, till two years postoperative. A through-out assessment of both their audiological and vestibular status will be carried out at multiple fixed timepoints over 2…
- Trial name
- NCT06021132
- Testing
- cochlear implant
- Where
- Denmark
- Volunteers
- 39 people
- Sponsor
- Aalborg University Hospital
End Stage Renal Disease on Dialysis
Intradialytic Kinetics of Cardiac Biomarkers During Hemodialysis and Hemodiafiltration
This randomized, crossover study aims to investigate the intradialytic kinetics of selected cardiac biomarkers in patients with end-stage renal disease treated with dialysis.
- Trial name
- NCT06526702
- Testing
- High-flux hemodialysis, Post-dilution hemodiafiltration
- Where
- Denmark
- Volunteers
- 26 people
- Sponsor
- Aalborg University Hospital
Benign Paroxysmal Positional Vertigo, BPPV
Treatment of Posterior Benign Paroxysmal Positional Vertigo With Mechanical Rotational Chair.
Comparison of treatment efficacy of Epley maneuver and 360 maneuver in a mechanical rotational chair (TRV chair) in patient with posterior benign paroxysmal positional vertigo (BPPV).
- Trial name
- NCT05834452
- Testing
- The Epley Maneuver, The 360 Degree Maneuver, Mechanical rotational chair
- Where
- Denmark
- Volunteers
- 128 people
- Sponsor
- Aalborg University Hospital
Mitochondrial Diseases, Bone Remodeling Disorder
The Impact of Mitochondrial Dysfunction on Human Bone Cell Metabolism and Remodelling
Cell and mice studies suggest mitochondrial dysfunction may cause altered bone structure. Hypothesis: Decreased mitochondrial energy production affects bone cell development and activity negatively.
- Trial name
- NCT05483738
- Testing
- Clinical assessment, blood samples, bone marrow and bone biopsy
- Where
- Denmark
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Aalborg University Hospital
Diabetes Mellitus, Type 2
TeleCare North Diabetes
This feasibility study will evaluate the feasibility of two telemonitoring designs for non-insulin treated T2D patients with an eye to identify the most suitable telemonitoring intervention for a future large-scale randomized…
- Trial name
- NCT06134934
- Testing
- Telemonitoring 1, Telemonitoring 2
- Where
- Denmark
- Volunteers
- 60 people
- Sponsor
- Aalborg University Hospital
Low Back Pain
Assessing the Quality of Telephone Follow-Up After Spine Surgery
The aim of this study is to investigate whether the quality of physiotherapy follow-up after spinal surgery can be maintained when conducted by telephone rather than in-person.
- Trial name
- NCT07173413
- Testing
- Telephone post-surgery physiotherapy follow-up, In person post-operative physiotherapy follow-up
- Where
- Denmark
- Volunteers
- 200 people
- Sponsor
- Aalborg University Hospital
Frailty in Older Adults, Functional Decline
Prevalence of Anticholinergics in Geriatric Patients With Acute Functional Deterioration
This study investigates the anticholinergic burden on patients seen in the Subacute mobile outpatient geriatric clinic in Aalborg, Denmark, between the years of 2024 and 2025.
- Conditions
- Frailty in Older Adults, Functional Decline, Anticholinergic Syndrome
- Trial name
- NCT07165574
- Testing
- No intervention as the study is observational
- Where
- Denmark
- Volunteers
- 100 people
- Sponsor
- Aalborg University Hospital
Pituitary, Aging
Age-related Differences in Response to Pituitary Stimulation Tests
The purpose of this study to age-related differences to the response of a combined pituitary stimulation test with TRH, LHRH and ACTH.
- Trial name
- NCT04572139
- Testing
- Pituitary stimulation test
- Where
- Denmark
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Aalborg University Hospital
Gabapentin
Prevalence of Gabapentinoids and Opioids in Geriatric Falls Patients
This study investigates the prescription patterns of gabapentinoids (gabapentin and pregabalin) in a geriatric fall clinic in Aalborg, Denmark, between 2013 and 2023.
- Trial name
- NCT06613802
- Testing
- Time
- Where
- Denmark
- Volunteers
- 800 people
- Sponsor
- Aalborg University Hospital
Pulmonary Embolism
Implementation of a Structured Post-pulmonary Embolism Follow-up Model
Venous thromboembolism (VTE), clinically presenting as deep vein thrombosis or pulmonary embolism (PE) is the third most frequent cardiovascular disease and is associated with substantial short- and long-term morbidity and…
- Trial name
- NCT06037096
- Testing
- Attend-PE model
- Where
- Denmark
- Volunteers
- 2,000 people
- Sponsor
- Aalborg University Hospital
IVF, Frozen Embryo Transfer (FET)
Maternal Cardiovascular Adaption to Pregnancy in IVF Patients Following Frozen Embryo Transfer (FET)
Aim of the study is to explore the effect of a lacking corpus luteum on maternal cardiovascular and metabolic adaption to pregnancy by the use of magnetic resonance imaging (MRI).
- Conditions
- IVF, Frozen Embryo Transfer (FET), Cardiovascular Adaption, Magnetic Resonance Imaging (MRI)
- Trial name
- NCT06471140
- Testing
- magnetic resonance imaging (MRI)
- Where
- Denmark
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Aalborg University Hospital
Arthroplasty, Replacement, Knee
Wearable Sensors for Monitoring Recovery After Total Knee Arthroplasty
The goal of this observational study is to investigate the potential of wearable sensors for monitoring the postoperative recovery of patients after TKA.
- Trial name
- NCT05992064
- Testing
- Measuring gait
- Where
- Denmark
- Volunteers
- 30 people
- Sponsor
- Aalborg University Hospital