Clinical trials: sponsored by Aalborg University Hospital
Arthritis, Rheumatoid, Arthritis, Psoriatic
Characterization of Immunogenicity of TNF Inhibitors in Arthritis Patients With Poorer Treatment Response.
The aim of the study is to explore whether the influence of gender, tobacco smoking and obesity on treatment response in tumor necrosis factor inhibitors (TNFIs) can be explained by high degree of inflammation, human leucocyte…
- Conditions
- Arthritis, Rheumatoid, Arthritis, Psoriatic, Spondylitis, Ankylosing
- Trial name
- NCT04731831
- Where
- Denmark
- Volunteers
- 120 people
- Sponsor
- Aalborg University Hospital
Tibial Shaft Fracture
Intramedullary Nailing vs External Ring Fixation for the Treatment of Tibial Shaft Fractures
This study is a multicenter pragmatic assessor blinded randomized and prospective clinical trial in which standard intramedullary nailing is compared with external ring fixator for patients with tibial shaft fractures.
- Trial name
- IMVEX (NCT03945669)
- Testing
- Intramedullary Nailing, External Ring fixation
- Where
- 3 sites in Denmark
- Volunteers
- 67 people
- Sponsor
- Aalborg University Hospital
Achilles Tendon Rupture
Early Progressive Strength Exercise for Treatment of Acute Achilles Tendon Rupture.
The purpose of this trial is to investigate the efficacy of standard care versus standard care combined with an early progressive exercise program in improving the function of the tendon and leg muscles after non-surgical treated…
- Trial name
- NCT04726189
- Testing
- Standard exercises, Standard exercises plus Early progressive exercises
- Where
- 2 sites in Denmark
- Volunteers
- 82 people
- Sponsor
- Aalborg University Hospital
Benign Paroxysmal Positional Vertigo, BPPV
The Accuracy of Manual BPPV Diagnostics When Using VNG Goggles.
The aim is to investigate the accuracy of manual diagnostics of benign paroxysmal positional vertigo (BPPV) by comparing it to BPPV diagnostics in mechanical rotational chair (TRV chair).
- Conditions
- Benign Paroxysmal Positional Vertigo, BPPV, Vertigo, Vestibular Disorder
- Trial name
- NCT05846711
- Testing
- BPPV diagnostic, TRV chair, VNG goggles
- Where
- Denmark
- Volunteers
- 215 people
- Sponsor
- Aalborg University Hospital
Central Nervous System Infections, Bacterial Meningitis
Central Nervous System Infections in Denmark
The Danish Study Group of Infections of the Brain is a collaboration between all departments of infectious diseases in Denmark. The investigators aim to monitor epidemiological trends in central nervous system (CNS) infections by…
- Conditions
- Central Nervous System Infections, Bacterial Meningitis, Viral Meningitis, Aseptic Meningitis
- Trial name
- DASGIB (NCT03418441)
- Testing
- Community-acquired CNS infections
- Where
- 8 sites in Denmark
- Volunteers
- 1,900 people
- Sponsor
- Aalborg University Hospital
Oropharynx Cancer
Proteome- and Methylation Profiles in Oropharyngeal Cancer
This clinical study aims to evaluate proteome- and methylation profiles in saliva in patients with oropharyngeal cancers
- Trial name
- PROMEO (NCT04567082)
- Testing
- Examination of saliva
- Where
- Denmark
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Aalborg University Hospital
Transient Ischemic Attack, Quality of Life
Life After Transient Ischemic Attack
Background: Transient ischemic attack (TIA) is defined as acute neurological symptoms of vascular origin, which resolves completely within 24 hours.
- Trial name
- LATIA (NCT05234528)
- Where
- Denmark
- Volunteers
- 355 people
- Sponsor
- Aalborg University Hospital
Obesity, Childhood, High Intensity Interval Training
"HIIT Med Kiloene".
In Denmark, 15% of children are overweight and 5% obese. Obese children and adolescents have several metabolic complications, such as pre-diabetes, hypertension, dyslipidaemia, and excess fat deposition in liver, already at a…
- Trial name
- NCT05465057
- Testing
- High intensity interval training (HIIT) + lifestyle intervention (TCOCT), Lifestyle intervention (TCOCT)
- Where
- Denmark
- Volunteers
- 172 people, healthy volunteers welcome
- Sponsor
- Aalborg University Hospital
Pain Syndrome
Pain After Removal of Mandibular Third Molars With or Without Advanced Platelet-rich Fibrin
Pain is the most common complication following surgical removal of an impacted mandibular third molar. Several risk factors may increase the intensity and duration of pain following removal of mandibular third molars.
- Trial name
- NCT06377839
- Testing
- Advanced platelet-rich fibrin in the ekstraction socket
- Where
- Denmark
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Aalborg University Hospital
Atrial Fibrillation, Arrhythmia
Cardiac Arrhythmias in Greenland
The study is a phd-study comprising several substudies focusing on cardiac arrhythmias, mainly atrial fibrillation, among Greenlanders in Greenland.
- Conditions
- Atrial Fibrillation, Arrhythmia, Autonomic Neuropathy
- Trial name
- NCT05200676
- Testing
- ePatch, SmartPill
- Where
- Greenland
- Volunteers
- 200 people
- Sponsor
- Aalborg University Hospital
Incontinence, Urinary, Enuresis, Nocturnal
Alarm Treatment for Combined Enuresis and Daytime Urinary Incontinence in Children
The aim is to examine whether alarm therapy in addition to urotherapy can have a beneficial effect in treating urinary incontinence children with combined daytime incontinence and enuresis.
- Conditions
- Incontinence, Urinary, Enuresis, Nocturnal, Enuresis
- Trial name
- ABDE (NCT04260646)
- Testing
- Enuresis Alarm Rodger and Timer watch (Rodger), Timer watch (Rodger)
- Where
- 4 sites in Denmark
- Volunteers
- 89 people
- Sponsor
- Aalborg University Hospital
NAFLD, Obesity
The MULTISITE Study
This study will investigate potential correlations and relationships between obesity and organ-specific complications, including non-alcoholic fatty liver disease (NAFLD), non-alcoholic fatty pancreas disease (NAFPD) and fatty…
- Conditions
- NAFLD, Obesity, Extracellular Vesicles, Weight Loss
- Trial name
- NCT05699863
- Testing
- Lifestyle intervention
- Where
- Denmark
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Aalborg University Hospital
Hypercapnic Respiratory Failure, COPD
Treatment of Acute Hypercapnic Respiratory Failure With OptiflowTM or Optiflow+DuetTM Nasal Cannula in COPD-patients
Hypothesis Treatment with HFNC and OptiflowTM+Duet can significantly reduce PaCO2 and normalize pH in patients with COPD exacerbation and acute hypercapnic failure, compared to HFNC with OptiflowTM.
- Trial name
- DUACT (NCT06257667)
- Testing
- Respiratory Support
- Volunteers
- 138 people
- Sponsor
- Aalborg University Hospital
Type 2 Diabetes, Bone Disease
Deep Phenotyping of Bone Disease in Type 2 Diabetes and Relations to Diabetic Neuropathy
Objectives: The goal of this cross sectional clinical trial is to examine the phenotype of bone disease in type 2 diabetes.The main aims are to: 1.
- Conditions
- Type 2 Diabetes, Bone Disease, Osteoporosis, Diabetic Neuropathy Peripheral
- Trial name
- NCT05642143
- Testing
- Dual Energy X-ray Absorbtiometry scan, High-resolution peripheral quantitative computed tomography, Microindentation
- Where
- Denmark
- Volunteers
- 300 people
- Sponsor
- Aalborg University Hospital
Cystitis Recurrent, Lactobacillus Infection
Bacterial Composition and Recurrent Cystitis in Postmenopausal Women After Treatment With Lactobacilli.
The goal of this clinical trial is to learn about the effect on the bacterial composition in the microbiome (the body's own bacteria) of urine, vagina and faeces after treatment with lactobacilli (lactobacilli's are a part of the…
- Trial name
- NCT05591742
- Testing
- FEMIDUR®
- Where
- Denmark
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Aalborg University Hospital
Transgenderism
Is Bioimpedance Analysis Accurate in Transgender Males?
Accurate fat mass and muscle mass assessment is an informative marker of an individual's health. However, the optimal method for assessing body composition in transgender males remains to be determined.
- Trial name
- NCT05728853
- Testing
- Assessment of body composition
- Where
- Denmark
- Volunteers
- 10 people
- Sponsor
- Aalborg University Hospital
Type 2 Diabetes Treated With Insulin
Diabetes teleMonitoring of Patients in Insulin Therapy
The trial is an open-label randomized controlled trial. Patients with T2D on insulin therapy will be randomized to a telemonitoring group (intervention) and a usual care group (control).
- Trial name
- DiaMonT (NCT04981808)
- Testing
- Telemonitoring
- Where
- Denmark
- Volunteers
- 331 people
- Sponsor
- Aalborg University Hospital
Healing Ulcer
High Protein Oral Nutritional Support With Special Nutrients in Patients With Type 2 Diabetes and Foot Ulcer
To assess the supplement of a high protein oral nutritional supplement enriched with arginin, zink, vitamin c and antioxidants on the healing of foot ulcers in patients with type 2 diabetes mellitus
- Trial name
- NCT05464407
- Testing
- Cubitan
- Where
- Denmark
- Volunteers
- 6 people
- Sponsor
- Aalborg University Hospital
Hereditary Diseases
Cell-based Non-invasive Prenatal Testing as an Alternative to Invasive Chorionic Villus Sampling
The study aims to evaluate cell-based non-invasive prenatal testing (cbNIPT) as an alternative to invasive chorionic villus sampling (CVS) in patients who achieve pregnancy following preimplantation genetic testing for hereditary…
- Trial name
- NCT05453474
- Testing
- Whole genome amplification
- Where
- Denmark
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Aalborg University Hospital
Frailty
Exercise and Nutrition Intervention for Frail Older Patients
The objective of this study is to evaluate the effect of a person-centered training and nutrition intervention six month after discharge in acutely admitted frail old medical patients on physical function.
- Trial name
- NCT05831982
- Testing
- Person-centered strength training and nutrition intervention, Standard training
- Where
- Denmark
- Volunteers
- 119 people
- Sponsor
- Aalborg University Hospital