Clinical trials: sponsored by Aalborg University Hospital
Hearing Loss
Innovation of Hearing Rehabilitation and Effects of Reform
The Danish health care system has been criticized for its structural inefficiency and latency to initiate proper hearing rehabilitation amongst hearing-impaired individuals.
- Trial name
- InHEAR (NCT05154539)
- Testing
- Remote digital assessment, Conventional physical assessment
- Where
- Denmark
- Volunteers
- 751 people, healthy volunteers welcome
- Sponsor
- Aalborg University Hospital
Dental Implant Failed
Single Crown Supported by Short Implant Versus Standard Implant in Conjunction With Maxillary Sinus Floor Augmentation.
Implant placement in the posterior part of the maxilla is frequently compromised due to atrophy of the alveolar process. Therefore, alveolar ridge augmentation is frequently necessary before or in conjunction with implant…
- Trial name
- NCT04518020
- Testing
- 40 patients will be randomly allocated to short implants and standard implants in conjunction with MSFA
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Aalborg University Hospital
Onychomycosis of Toenail
Laser Treatment of Toenail Onychomycosis With a 1064 nm Nd:YAG-laser
This study aims to assess if laser treatment can cure fungal infection in toenails. Nail clippings from eligible subjects were obtained and randomised into two groups.
- Trial name
- NCT05260450
- Testing
- 1064 nm Nd:YAG-laser therapy
- Where
- Denmark
- Volunteers
- 20 people
- Sponsor
- Aalborg University Hospital
Dental Implant Failed
Sinus Floor Augmentation and Graft Compared Sinus Membrane Elevation With Blood Coagulum. A Randomized Controlled Trial
Implant placement in posterior maxilla is often compromised or impossible due to atrophy of the bone and pneumatisation of the maxillary sinus. Thus, alveolar ridge augmentation is frequently necessary.
- Trial name
- NCT04667260
- Testing
- Maxillary sinus membrane elevation, Maxillary sinus floor augmentation
- Where
- Denmark
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Aalborg University Hospital
Pulmonary Embolism
Non-invasive Diagnosis of Pulmonary Embolism by Use of Biomarkers in Exhaled Breath Condensate
In this study, a new, non-invasive method for diagnosis of pulmonary embolism (PE) will be tested. In pre-clinical studies, we have identified 151 putative biomarkers for pulmonary embolism in the exhaled breath condensate (EBC).
- Trial name
- NCT04010760
- Testing
- Test of biomarkers for PE in EBC
- Where
- Denmark
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Aalborg University Hospital
Fall, Fall Injury
FRIDs and Fall Risk Among Older Adults
The European Geriatric Medicine Society (EuGMS) Task and Finish Group published a consensus paper on fall-risk increasing drugs. However, the group did not reach consensus on 17 medication classes as potential FRIDs.
- Conditions
- Fall, Fall Injury, Aging, Aged
- Trial name
- NCT05169476
- Where
- 5 sites in Denmark
- Volunteers
- 241 people, healthy volunteers welcome
- Sponsor
- Aalborg University Hospital
Rheumatoid Arthritis, Systemic Lupus Erythematosus
The Effect of Deep Breathing and Transcutaneus Electrical Nerve Stimulation on Heart Rate Variability
This interventional study aims to investigate the effect of deep breathing (DB) and transcutaneous electrical vagus nerve stimulation (tVNS) on heart rate variability (HRV) in healthy participants and patients with rheumatoid…
- Conditions
- Rheumatoid Arthritis, Systemic Lupus Erythematosus, Healthy Participants
- Trial name
- NCT05157334
- Testing
- Non-invasive auricular electrical transcutaneous vagus nerve stimulation, Deep breathing
- Where
- Denmark
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Aalborg University Hospital
Neuropathy, Diabetic, Neuropathy, Painful
Methods of Early Detection and Grading Of Diabetic Peripheral Neuropathy (MEDON)
MEDON aims to examine new methods for early detection and grading of diabetic peripheral neuropathy focusing on both small- and large nerve fibers.
- Trial name
- MEDON (NCT04078516)
- Testing
- Perception Threshold Tracking (PTT), Axon-flair mediated respons, Heart rate variability
- Where
- Denmark
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Aalborg University Hospital
Delirium
Improved Patient Safety for Acute Restless Medical Patients With Supplemental Observation
The aim of the study is to investigate whether supplemental camera observation directly linked to the nurse's phone will improve patient safety for acute medical care patients', who are restless, confused or in risk of…
- Trial name
- NCT04841122
- Testing
- Camera observation
- Where
- Denmark
- Volunteers
- 8 people
- Sponsor
- Aalborg University Hospital
Hypoxemic Respiratory Failure, Oxygen Toxicity
Handling Oxygenation Targets in the Intensive Care Unit
Handling oxygenation targets (HOT) is standard of care in the intensive care unit (ICU), however the quality and quantity of evidence is low and potential harm has been reported.
- Trial name
- HOT-ICU (NCT03174002)
- Testing
- Oxygen
- Where
- 37 sites in Denmark, Finland and 5 more
- Volunteers
- 2,928 people
- Sponsor
- Aalborg University Hospital
Pacemaker DDD, Atrioventricular Block
Risk of Pacing-induced Cardiomyopathy
This study will evaluate the association between right ventricular pacing and the risk of pacing-induced cardiomyopathy.
- Conditions
- Pacemaker DDD, Atrioventricular Block, Pacing-Induced Cardiomyopathy
- Trial name
- NCT04269733
- Testing
- Right ventricular pacing
- Where
- Denmark
- Volunteers
- 153 people
- Sponsor
- Aalborg University Hospital
Diabetes Mellitus, Type 1, Type 1 Diabetes Mellitus
Treatment of Diabetic Neuropathy With Liraglutide
The purpose of this trial is to explore whether liraglutide has a long term effect on clinical symptoms and biomarkers in patients with diabetic neuropathy.
- Trial name
- TODINELI (NCT02138045)
- Testing
- Liraglutide treatment
- Where
- Denmark
- Volunteers
- 39 people
- Sponsor
- Aalborg University Hospital
Non-small-cell Lung Cancer, Carcinoma, Non-Small-Cell Lung
Immune Checkpoint Inhibitors in Advanced Non-small Cell Lung Cancer and Discovery of New Biomarkers
Lung cancer patients have a poor prognosis and only around 20 % is alive after 5 years. However, for advanced non-small cell lung cancer immunotherapy has become a cornerstone of treatment.
- Conditions
- Non-small-cell Lung Cancer, Carcinoma, Non-Small-Cell Lung, Lung Neoplasm
- Trial name
- LimBio (NCT03658460)
- Testing
- DNA sequencing
- Where
- Denmark
- Volunteers
- 60 people
- Sponsor
- Aalborg University Hospital
Recurrent Miscarriage, Spontaneous Abortion
Low Plasma Mannose Binding Lectin (p-MBL) Level is a Risk Factor for Recurrent Pregnancy Loss (RPL)
The present study is based on the hypothesis, that recurrent pregnancy loss (RPL) is associated with abnormal plasma mannose binding lectin (p-MBL) level.
- Conditions
- Recurrent Miscarriage, Spontaneous Abortion, Mannose-Binding Lectin Deficiency, Habitual Abortion
- Trial name
- NCT04017754
- Where
- Denmark
- Volunteers
- 452 people
- Sponsor
- Aalborg University Hospital
Head and Neck Cancer, Squamous Cell Carcinoma
Epigenetic Changes in Head and Neck Cancer
With this study, the investigators will investigate the epigenetic changes, which may contribute to the development of head and neck squamous cell carcinomas.
- Conditions
- Head and Neck Cancer, Squamous Cell Carcinoma, Head and Neck Squamous Cell Carcinoma, Head and Neck Neoplasms
- Trial name
- NCT04260074
- Where
- Denmark
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Aalborg University Hospital
Consciousness Monitors, Laparoscopy
Bispectral Index and Surgical Field
This study investigates whether BIS monitor assisted anesthesia improves surgical space conditions during gynecological benign laparoscopic procedures.
- Trial name
- NCT03911544
- Testing
- BIS monitor
- Where
- Denmark
- Volunteers
- 160 people
- Sponsor
- Aalborg University Hospital
Psoriatic Arthritis, Hand Osteoarthritis
CBD Treatment in Hand Osteoarthritis and Psoriatic Arthritis.
A randomized, placebo-controlled trial with blinded outcome assessments will be conducted to evaluate the efficacy and safety of CBD in patients with Hand-OA and PsA during a 12-week treatment period.
- Trial name
- NordCAN (NCT03693833)
- Testing
- Cannabidiol
- Where
- Denmark
- Volunteers
- 136 people
- Sponsor
- Aalborg University Hospital
Coronary Artery Disease
Nordic-Baltic Coronary Revascularization Study in Patients With Proximal Left Descending Coronary Artery (LAD) Lesion.
The Nordic-Baltic Heart Team Initiative for improved long-term coronary artery revascularization outcome compares quality of life and survival after coronary bypass grafting (CABG) vs.
- Trial name
- NOBLE-LAD (NCT03538886)
- Testing
- Coronary artery bypass grafting (CABG), Percutaneous coronary intervention (PCI)
- Where
- Denmark
- Volunteers
- 4 people
- Sponsor
- Aalborg University Hospital
Survival, Prosthesis, Peri-Implantitis
Maxillary Sinus Floor Augmentation With Different Grafting Materials
Implant placement in the posterior maxilla is compromised due to atrophy of the alveolar process and maxillary sinus pneumatisation. Bone augmentation is frequently necessary before or in conjunction with implant placement.
- Conditions
- Survival, Prosthesis, Peri-Implantitis, Patient Satisfaction
- Trial name
- NCT04749953
- Testing
- Maxillary sinus floor augmentation
- Where
- Denmark
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Aalborg University Hospital
Pacing-Induced Cardiomyopathy, AV Block
His Pacing Feasibility and Cardiac Electrical Activation
This study will examine the clinical feasibility of His pacing in patients with expected high demand for ventricular pacing and no established indication for cardiac resynchronization therapy.
- Conditions
- Pacing-Induced Cardiomyopathy, AV Block, Heart Failure
- Trial name
- NCT04739553
- Testing
- His Pacing
- Volunteers
- 25 people
- Sponsor
- Aalborg University Hospital