Clinical trials: sponsored by Aarhus University Hospital
Growth Hormone Deficiency
Diurnal Variation of Exogenous Peptides (GH Puls/Jurgita I)
This is an exploratory trial with four cross-over arms measuring the pharmacokinetic and pharmacodynamic profiles of growth hormone using two different modes of growth hormone administration (subcutaneous infusion into the…
- Trial name
- NCT01090778
- Testing
- Norditropin SimpleXx (growth hormone)
- Where
- 2 sites in Denmark
- Volunteers
- 8 people
- Sponsor
- Aarhus University Hospital
Prostate Cancer, Metastasis
A Safety Study of ZD4054 in Prior Chemotherapy Treated Patients With Metastatic Hormone-resistant Prostate Cancer
This is a prospective, open, one-arm, two-centre, Phase II clinical safety pilot-study. The trial is designed to gain initial safety and efficacy-related data on once-daily orally administered ZD4054 10 mg in prior chemotherapy…
- Trial name
- DAPROCA-1 (NCT01000948)
- Testing
- ZD4054
- Where
- Denmark
- Volunteers
- 24 people
- Sponsor
- Aarhus University Hospital
Uterine Cervical Neoplasms
Repetitive Functional Imaging in Locally Advanced Cervical Cancer
Background: The Apparent Diffusion Coefficient (ADC) acquired by Diffusion Weighted Imaging (DWI-MR) has been shown to correlate with cellular density.
- Trial name
- IMAP (NCT01989364)
- Where
- 3 sites in Belgium, Denmark and 1 more
- Volunteers
- 50 people
- Sponsor
- Aarhus University Hospital
Acute Lymphoblastic Leukaemia
A Drug Monitoring Study on PEG-asparaginase Treatment in Children Diagnosed Acute Lymphoblastic Leukaemia
Asparaginase is an important drug i the treatment of childhood leukaemia. The aim of this project is to study the pharmacokinetics, pharmacodynamics and antibody development and hypersensitivity reactions during prolonged…
- Trial name
- NCT01272440
- Where
- Denmark
- Volunteers
- 200 people
- Sponsor
- Aarhus University Hospital
Coronary Artery Disease, Angina Pectoris
SORT-OUT VI - Randomized Clinical Comparison of Biomatrix Flex® and Resolute Integrity®
To perform a randomized comparison between the BioMatrix Flex™ and the Resolute Integrity® stents in the treatment of unselected patients with ischemic heart disease.
- Trial name
- SO VI (NCT01956448)
- Testing
- Drug eluting stent
- Where
- 3 sites in Denmark
- Volunteers
- 2,800 people
- Sponsor
- Aarhus University Hospital Skejby
Coronary Artery Disease, Angina Pectoris
SORT-OUT V - Randomised Clinical Comparative Study of the Nobori and the Cypher Stent.
To perform a randomized comparison between the Cypher Select+ stent and the Nobori stent in the treatment of unselected patients with ischaemic heart disease.
- Trial name
- SORT-OUT V (NCT01254981)
- Testing
- Percutaneous coronary intervention (PCI)
- Where
- 3 sites in Denmark
- Volunteers
- 2,504 people
- Sponsor
- Aarhus University Hospital Skejby
Coronary Artery Disease, Angina Pectoris
Comparison of Cypher Select and Taxus Express Coronary Stents
Randomized nine months clinical comparison of implantation of Taxol eluting (Taxus Express) and Sirolimus eluting (Cypher Select) stents in non-selected patients with coronary artery disease.
- Trial name
- SORT-OUTII (NCT00388934)
- Testing
- Drug eluting stent
- Volunteers
- 2,095 people
- Sponsor
- Aarhus University Hospital Skejby
Arthritis, Rheumatoid
A Study of the Effect of Supervised Exercise Programme in Patients With Rheumatoid Arthritis
The purpose of this study is to compare the effectiveness of a supervised high-intensity exercise programme followed by an unsupervised exercise programme to an unsupervised exercise programme in patients with Rheumatoid…
- Trial name
- NCT01553305
- Testing
- Supervised high-intensity exercise programme, Exercise programme
- Where
- Denmark
- Volunteers
- 52 people
- Sponsor
- Aarhus University Hospital
Metabolic Syndrome
Effect of Arabinoxylan and Rye Kernels on Second Meal Responses
Sedentary lifestyles and increasing obesity are main causes of the global increase in the prevalence of the metabolic syndrome (Mets) and type 2 diabetic (T2DM).
- Trial name
- NCT01583270
- Testing
- Arabinoxylan, Rye kernel, Arabinoxylan and rye kernels
- Where
- Denmark
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Aarhus University Hospital
Metabolic Syndrome
ButCoIns - Metabolic Effects of Resistent Starch and Arabinoxylans in Subjects With Metabolic Syndrome
Background Life style related disease is an increasing problem all over the world. The Metabolic Syndrome (MetS) is a condition characterized by abdominal obesity, high blood lipids, high blood pressure and slightly elevated…
- Trial name
- ButCoIns (NCT01584427)
- Testing
- Healthy Carbohydrate Diet vs. Western Style Diet
- Where
- Denmark
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Aarhus University Hospital
Diabetes Mellitus, Type 1, Ischemia
Non-enhanced Magnetic Resonance Angiography of Diabetic Ischemic Lower Limbs
Diabetic foot ulcers often progresses after many years of diabetes where the patients system is so damaged that normal heeling of ulcers cannot happen.
- Conditions
- Diabetes Mellitus, Type 1, Ischemia, Foot Ulcer
- Trial name
- NCT01614379
- Where
- 2 sites in Denmark
- Volunteers
- healthy volunteers welcome
- Sponsor
- Aarhus University Hospital
Hip Dysplasia
Movement Pattern in Patients With Hip Dysplasia
The purpose of this study is to examine the movement pattern in patients with hip dysplasia preoperative, six and 12 month after minimally invasive approach for Periacetabular osteotomy (PAO).
- Trial name
- NCT01344421
- Testing
- Minimally invasive approach for Periacetabular osteotomy
- Where
- Denmark
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Aarhus University Hospital
Ultrasound, Sterile Puncture Area
Ultrasound-guided Blood Sampling With a Sterile and Dry Puncture Area
Thousands of vein punctures are done every day at hospitals worldwide. Vein puncture are performed in connection with blood sampling, peripheral intravenous catheter (PIV) placement or blood donation.
- Conditions
- Ultrasound, Sterile Puncture Area, Blood Sampling
- Trial name
- NCT01785225
- Testing
- A product type of the modified commercial drape Tegaderm (R)
- Where
- Denmark
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Aarhus University Hospital
Inflammation, Glucose Metabolism Disorders
Endotoxin & Cytokines. Do Protein Loss and Metabolic Effects Depend on Central Nervous System (CNS) Activation of Stress Hormones or on Local Mechanisms in Muscle and Fat?
Main objective : The purpose of this study is to prove that the effects of bacterial endotoxin and cytokine TNF-α, on protein loss, fatty acid release, and glucose metabolism depend on two mechanisms: 1.
- Trial name
- NCT01452958
- Testing
- TNF-alpha, Endotoxin
- Where
- Denmark
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Aarhus University Hospital
Type 2 Diabetes Mellitus
Diurnal Variation of Exogenous Peptides (Endogenous Insulin Jurgita II)
This is an exploratory trial with two cross-over arms investigating pharmacokinetic profiles of endogenous and exogenous insulin in type 2 diabetes mellitus patients treated with continuous subcutaneous Insulin Aspart infusion…
- Trial name
- NCT01510093
- Testing
- Insulin Aspart 100 IE/ml
- Where
- Denmark
- Volunteers
- 10 people
- Sponsor
- Aarhus University Hospital
Atrophic Acne Scars
Treatment of Atrophic Acne Scars With a Fractional CO2 Laser at 1 Versus 3 Months Intervals
To compare efficacy and adverse effects of fractional CO2 laser of acne scars treatment with 1 versus 3 months intervals
- Trial name
- NCT01773343
- Testing
- Laser
- Where
- Denmark
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Aarhus University Hospital
Streptococcal Acute Tonsillitis
Procalcitonin-guided Detection of Streptococcal Acute Tonsillitis
The primary purpose of the present study is to investigate the usefulness of Procalcitonin as a supplement to the Streptococcal antigen test and Centor criteria in the differential diagnose making between Streptococcal and…
- Trial name
- NCT01657968
- Where
- Denmark
- Volunteers
- 200 people
- Sponsor
- Aarhus University Hospital
Hepatitis C, Chronic, Cognition Disorders
Study of Cerebral Function in Patients With Chronic Hepatitis C Infection (HCV/CNS)
Patients with HCV infection often suffer from chronic fatigue, depression and reduced cognition, even before evolving severe liver fibrosis, liver cirrhosis and hepatic encephalopathy.
- Conditions
- Hepatitis C, Chronic, Cognition Disorders, Fatigue Syndrome, Chronic, Major Depressive Disorder
- Trial name
- NCT00788918
- Testing
- Interferon and ribavirin
- Where
- Denmark
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Aarhus University Hospital
Insulin-like Growth Factor I, Insulin-like Growth Factor II
Neurotrophic Factors in Cerebrospinal Fluid in Diabetic Patients With Polyneuropathy
Background: The pathogenetic factors underlying development of diabetic polyneuropathy (DP) remain unclear. Reduced neurotrophic stimulation has been proposed as a possible mechanism.
- Conditions
- Insulin-like Growth Factor I, Insulin-like Growth Factor II, Diabetes Complications, Polyneuropathies
- Trial name
- NCT01718015
- Where
- Denmark
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Aarhus University Hospital
Bacteremia, Neoplasms
Taurolidine Lock Solution in the Prevention of Catheter Related Bacteremia
Children with cancer need a long term tunnelled central venous catheter (TCVC) for the entire duration of their treatment. TCVCs are locked with heparin when not in use.
- Trial name
- NCT00735813
- Testing
- Taurolock, Heparin
- Where
- Denmark
- Volunteers
- 129 people
- Sponsor
- Aarhus University Hospital