Clinical trials: completed, sponsored by Al-Azhar University
Class II Malocclusion
Comparative Effect of Conventional and 3D-printed Twin Block Appliances on Soft Tissue Changes
: To evaluate the effectiveness of functional device treatment using both 3D-printed and conventional Twin Block appliances on soft tissue changes during growth modification in Class II malocclusion.
- Trial name
- Clinic Radiogr (NCT07795138)
- Testing
- Twin Block
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Class II Malocclusion
Conventional Versus 3D Printed Twin Block Appliances in Growth Modification of Class II Malocclusion
The present study was conducted to evaluate the outcomes of conventionl versus 3D printed twin block appliances in growth modification of class II malocclusion (comparative clinical study) in both groups.
- Trial name
- RCT (NCT07792525)
- Testing
- Twin Block
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Zygomaticomaxillary Complex (ZMC) Fractures
Evaluation of Custom-Made Plates in the Treatment of Zygomaticomaxillary Complex (ZMC) Fractures.
This prospective, single-arm clinical trial evaluated the clinical and radiographic outcomes of custom-made, 3D-printed titanium plates in the surgical treatment of unilateral zygomaticomaxillary complex (ZMC) fractures.
- Trial name
- NCT07788885
- Testing
- Custom-made 3D-printed titanium plate
- Where
- Egypt
- Volunteers
- 10 people
- Sponsor
- Al-Azhar University
Immediate Implant Placement in Chronic Infected Socket
Efficacy of Mixture of Vancomycin With Xenograft for Immediate Implant Placement in Chronic Infected Socket
Adding local vancomycin to xenografts greatly benefits stability, bone density, and limits marginal bone loss in dental implants in infected socket.
- Trial name
- RCT (NCT07784075)
- Testing
- immediate dental implants Placement in Chronic Infected Socket
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
To Evaluate the Effectiveness of Intra-canal Nano-ketrolac as a Medicament in Reducing Post-endodontic Pain in Patients Undergoing Root Canal Treatment
The Effect of Intra-Canal Ketorolac Application on Post-Endodontic Pain
After obtaining informed consent, the procedure begins with the administration of local anesthesia to ensure patient comfort. A standard approach involves using 2% lidocaine with 1:100,000 epinephrine, delivered either via…
- Trial name
- Post-Endodonti (NCT07064083)
- Testing
- intracanal nano-ketrolac, ketrolac gel
- Where
- Egypt
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Periodontal Intrabony Defects, Stage III Grade B Periodontitis
Sub-junctional Pinhole Technique
Pinhole Regenerative Therapy (PRT) following minimally invasive non-surgical periodontal therapy (MINST) in the treatment of intrabony defects associated with Stage III Grade B periodontitis.
- Trial name
- PRT (NCT07763223)
- Testing
- Sub-junctional Pinhole Technique (S-PHT)
- Where
- Egypt
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Acne
577-nm Diode Laser in the Treatment of Non -Inflammatory Acne
The aim of this study is to evaluate the clinical efficacy and safety of the 577 nm diode laser in the treatment of non -inflammatory acne.
- Trial name
- NCT06909344
- Testing
- 577 nm Diode laser
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Metformin Gel, Bone Healing
Effect of Metformin Gel on Guided Bone Regeneration Around Immediate Dental Implant at Posterior Maxillary Region
To evaluate, by standardized radiographic follow-up, whether locally delivered 1% metformin gel improves bone healing around immediately placed dental implants augmented with GBR.
- Conditions
- Metformin Gel, Bone Healing, Guided Bone Regeneration, Crestal Bone Loss
- Trial name
- MET-GBR (NCT07770087)
- Testing
- Metformin 1% Topical Gel, immediate Dental Implant Placement With Guided Bone Regeneration
- Where
- 2 sites in Egypt
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Urethral Stricture
Factors Predicting Urethral Stricture Recurrence After Dorsal Onlay Augmented, Buccal Mucosal Graft Urethroplasty
In this observational study, the investigators will evaluate potential risk factors associated with urethral stricture recurrence after augmentation anterior urethroplasty using dorsal onlay buccal mucosal Graft during the past…
- Trial name
- NCT04357080
- Testing
- Urethroplasty
- Where
- Egypt
- Volunteers
- 266 people
- Sponsor
- Al-Azhar University
Kidney Calculi, Radiation Exposure
Safety and Efficacy of Fluoroscopy-free Technique During Retrograde Intrarenal Surgery for Renal Stones
Aiming to reduce radiation exposure to patients and physicians, the investigators conduct this study protocol to evaluate the possibility of performing retrograde intrarenal surgery (RIRS) under direct visualization without…
- Conditions
- Kidney Calculi, Radiation Exposure, Retrograde Intrarenal Surgery
- Trial name
- NCT05269108
- Testing
- Fluoroscopy-free RIRS, Standard RIRS
- Where
- Egypt
- Volunteers
- 503 people
- Sponsor
- Al-Azhar University
Renal Stone, Percutaneous Nephrolithotomy
Mini-PNL, RIRS, and ESWL for Treatment of Medium-Sized, High-Density, Non-Lower Pole, Renal Stones
The optimal management of medium-sized renal stones remains quite challenging and continues to be contested. In the present study, the investigators will compare mini-PNL, RIRS and SWL in the treatment of non- lower pole, medium…
- Conditions
- Renal Stone, Percutaneous Nephrolithotomy, Retrograde Intrarenal Surgery, Extracorporeal Shockwave Lithotripsy
- Trial name
- NCT04856722
- Testing
- mini-PNL, RIRS, SWL
- Where
- Egypt
- Volunteers
- 253 people
- Sponsor
- Al-Azhar University
Renal Stone, Extracorporeal Shockwave Lithotripsy
Mini- Percutaneous Nephrolithotomy Versus Extracorporeal Shock Wave Lithotripsy for High Density Renal Stones
Several studies were conducted to compare extracorporeal shockwave lithotripsy (SWL) and percutaneous nephrolithotomy (PNL) as treatment options for medium size lower caliceal high dense stones.
- Conditions
- Renal Stone, Extracorporeal Shockwave Lithotripsy, Percutaneous Nephrolithotomy
- Trial name
- NCT04346134
- Testing
- mini-PNL, SWL
- Where
- Egypt
- Volunteers
- 72 people
- Sponsor
- Al-Azhar University
Renal Calculi, Renal Anomaly
RIRS for Treatment of Stones in Congenital Anomalous Kidneys
The anatomic renal abnormalities like altered spatial relations with adjacent organs, abnormal calyceal orientation, and anomalous vascular patterns make the active treatment of stones in the congenitally malformed kidney a great…
- Trial name
- NCT05240170
- Testing
- RIRS, SWL
- Where
- Egypt
- Volunteers
- 160 people
- Sponsor
- Al-Azhar University
Bonding
Bond Strength Evaluation
This study was evaluated the effect of dimethyl sulfoxide pretreatment on tensile bond strength and nanoleakage of resin composite bonded to aged dentin.
- Trial name
- DMSO (NCT07196618)
- Testing
- dimethyl sulfoxide, Cholorhexidine
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Al-Azhar University
Frontal Sinusitis, Endoscopic Sinus Surgery
Radiological and Surgical Analysis of Frontal Recess Variations in Endoscopic Sinus Surgery
Introduction The frontal recess is a narrow and anatomically variable region that forms the frontal sinus drainage pathway. Variations in its anatomy, particularly those related to the agger nasi cell and other frontal recess…
- Conditions
- Frontal Sinusitis, Endoscopic Sinus Surgery, Frontal Sinus Recess
- Trial name
- NCT07748806
- Testing
- endosocpic sinus surgery
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Al-Azhar University
Cervical Disc Disease
Clinical and Radiological Outcomes of Anterior Cervical Discectomy and Fusion by Zero Profile Anchored Cage for Cervical Degenerative Disc Disease
The incidence of degenerative cervical conditions is increasing with the aging population, and it is well-recognized as a primary cause of myelopathy, radiculopathy, and disc herniation.
- Trial name
- NCT07743801
- Testing
- Anchored cage for CDD
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Al-Azhar University
Dental Crowding, Malocclusion, Angle Class I
The Reliability and Validity of Little's Irregularity Index Assessment
The primary aim of the current study was to estimate the validity, reliability, and repeatability of LII measurements
- Trial name
- LII (NCT07745855)
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Al-Azhar University
Turbinate Hypertrophy, Adenoidectomy
Adenoidectomy With or Without Partial Inferior Turbinectomy for Pediatric Nasal Obstruction
Nasal obstruction is a common problem in children and is frequently caused by adenoid hypertrophy with concomitant inferior turbinate hypertrophy, leading to sleep-disordered breathing and reduced quality of life.
- Conditions
- Turbinate Hypertrophy, Adenoidectomy, Adenoid Hypertrophy, Turbinate Surgery
- Trial name
- NCT07745868
- Testing
- adenoidectomy, Adenodiectomy and bilateral partial infeiror turbienctomy
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Al-Azhar University
Bell Palsy
Ultrasound-guided Combined Perineural and Intramuscular Dextrose Injection for Management of Refractory Bell's Palsy
Bell's palsy (BP) is characterized by idiopathic acute weakness of the facial muscles associated with compression of the facial nerve.
- Trial name
- NCT07728331
- Testing
- Ultrasound-guided combined perineural and intramuscular dextrose injection.
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Al-Azhar University
Periodontitis
Periodontitis Severity and Associated Factors Among Egyptian Males and Females
This cross-sectional study aims to evaluate and compare the severity of periodontitis between a group of Egyptian males and females.
- Trial name
- NCT07721337
- Testing
- Clinical Periodontal Examination and Questionnaire
- Where
- Egypt
- Volunteers
- 380 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University