Clinical trials: sponsored by Alexandria University
Hemodialysis Patient, Dry Weight
VEXUS and Assessment of Dry Weight of Patients on Hemodialysis
This is a prospective, single-arm study that will be conducted over a period of 24 weeks. The same maintenance HD patients will be followed sequentially in two study phases, with each patient serving as their own control.
- Trial name
- NCT07721636
- Testing
- ULTRASOUND for volume assessment
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Alexandria University
Keloid Scars, Hypertrophic Scar
Microneedling vs. 5-Fluorouracil or Steroid Injections for Hypertrophic Scars and Keloids
The goal of this clinical trial is to learn about the efficacy and safety of microneedling-assisted 5-fluorouracil delivery in comparison with intralesional 5-fluorouracil, intralesional corticosteroid, and microneedling with…
- Trial name
- MIST (NCT07718269)
- Testing
- Microneedling with 5-Fluorouracil, Intralesional 5-fluorouracil, Intralesional Triamcinolone Acetonide
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Alexandria University
Cancer, Chemotherapy
Effect of AI-Assisted Expressive Writing on Anxiety, Emotional Distress, and Quality of Life Among Patients Receiving Chemotherapy
This study aims to evaluate the effect of an AI-assisted expressive writing intervention on anxiety, emotional distress, and quality of life among patients receiving chemotherapy.
- Conditions
- Cancer, Chemotherapy, Anxiety
- Trial name
- NCT07713381
- Testing
- AI-Assisted Expressive Writing, Active Comparator: Routine Care Group
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Alexandria University
Breast Cancer
Nurse-Delivered Adapted MBSR During Breast Cancer Radiotherapy
This randomized study examined whether adding a condensed mindfulness programme to standard radiotherapy care could improve psychosocial outcomes among women treated for breast cancer.
- Trial name
- NCT06025799
- Testing
- Adapted mindfulness-based stress reduction
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Alexandria University
Symptomatic Irreversible Pulpitis (SIP)
Clinical and Radiographic Evaluation of Laser Assisted Pulpotomy in Immature Permanent Molars With Symptoms Indicative of Irreversible Pulpitis
The goal of this clinical trial is to assess the clinical and radiographic success rate of Laser pulpotomy procedure done in immature permanent molars with symptoms indicative of irreversible pulpitis..
- Trial name
- NCT07704463
- Testing
- Application of 660 nm diode laser, Application of 970 nm diode laser + MTA, Conventional MTA pulpotomy (control group)
- Where
- Egypt
- Volunteers
- 57 people
- Sponsor
- Alexandria University
Uterine Fibroids (Leiomyoma), Myomectomy
Bilateral Uterine Artery Occlusion During Laparoscopic Myomectomy
The current study is a multiple-arm, single blinded, and controlled randomized trial. It will be conducted in two gynecological endoscopy centers: • ElShatby University Hospital, a tertiary level hospital in Alexandria, Egypt.
- Conditions
- Uterine Fibroids (Leiomyoma), Myomectomy, Myomectomy; Surgical Blood Loss
- Trial name
- NCT07352761
- Testing
- Temporary clipping of uterine artery, Temporary occlusive suturing of uterine artery, Bipolar coagulation of uterine arteries
- Where
- 2 sites in Egypt
- Volunteers
- 60 people
- Sponsor
- Alexandria University
Dexmedetomidine, Magnesium Sulfate
Intraperitoneal Dexmedetomidine Versus Magnesium as Adjuvants to Bupivacaine in Laparoscopic Cholecystectomy
Although both dexmedetomidine and magnesium sulphate have been individually evaluated as adjuvants to local anesthetics, direct comparisons between the two agents in intraperitoneal instillation during laparoscopic…
- Conditions
- Dexmedetomidine, Magnesium Sulfate, Laparoscopic Cholecystectomy
- Trial name
- NCT07693621
- Testing
- Bupivacaine 100 mg + dexmedetomidine 1 µg/kg, Bupivacaine 100 mg + magnesium sulphate 50 mg/kg
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Alexandria University
Percutaneous Nephrolithotomy (PCNL)
Intrathecal Fentanyl and Dexmedetomidine Added to Bupivacaine for Subarachnoid Anaesthesia for Percutaneous Nephrolithotomy
Regular bupivacaine dosages are linked to considerable sympathetic block, as well as persistent and severe sensory and motor block, which may not be desired for certain individuals.
- Trial name
- NCT06957301
- Testing
- Intrathecal Fentanyl Group (F), intrathecal dexmedetomidine group(D)
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Alexandria University
Caries,Dental, Plaque, Dental
Oral Health Education and Message Framing Effect on Oral Health Status of Refugees in Egypt
Refugees, facing forced displacement and often exposed to traumatic experiences, represent a vulnerable population with unique healthcare needs. Oral health is considered a prominent factor that contributes to quality of life.
- Conditions
- Caries,Dental, Plaque, Dental, Gingivitis, Oral Health Quality of Life (OHQoL) Was Assessed
- Trial name
- NCT06649760
- Testing
- Gain and loss framed mobile text messages
- Where
- Egypt
- Volunteers
- 303 people
- Sponsor
- Alexandria University
Empyema, Pleural
Trial of Antiseptic Irrigation for Pleural Infection
Pleural antiseptic irrigation (PAI) is used in conjunction with open drainage for treating adults with chronic post-thoracotomy empyema.
- Trial name
- RINSE (NCT05546762)
- Testing
- Povidone-iodine solution, Normal saline
- Where
- Egypt
- Volunteers
- 22 people
- Sponsor
- Alexandria University
Chronic Diseases, Balance Disorders
AI-Based Tai Chi and Baduanjin for Improving Balance and Reducing Fall Risk in Adults With Chronic Diseases
This study aims to examine the effects of an AI-based mobile application delivering Tai Chi and Baduanjin exercises on balance and fall risk in adults with chronic diseases.
- Trial name
- NCT07672704
- Testing
- Tai Chi Exercise Program, Baduanjin Exercise Program
- Where
- Egypt
- Volunteers
- 120 people
- Sponsor
- Alexandria University
TMJ Disc Disorder
Comparison Between Different Concentrations of Ozone Gas as an Intra-articular Injection for Treatment of Internal Derangement of Tempromandibular Joint
The intra-articular injection is considered the first line of minimally invasive treatment of joint disease as it has an analgesic, antimicrobial effect and an immune system stimulating action as it is one of the most powerful…
- Trial name
- NCT07523451
- Testing
- Patients will be treated with 2ml ozone oxygen mixture with concentration 6 micron/ml, Patients will be treated with 2ml ozone oxygen mixture with concentration 12 micron/ml
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Alexandria University
Anemia in Dialysis-dependent CKD Patients
Effect of Low Doses of Hypoxia-inducible Factor- Prolyl Hydroxylase Enzyme Inhibitor Plus Iron in the Treatment of Anemia in Dialysis-dependent Chronic Kidney Disease Patients
this study aims to : 1. To compare the efficacy of combining low doses of Roxadustat Hypoxia-Inducible Factor (HIF)-Prolyl Hydroxylase (PHD) inhibitor and iron versus standard treatment with erythropoietin-stimulating agents…
- Trial name
- NCT06115421
- Testing
- Roxadustat
- Where
- Egypt
- Volunteers
- 72 people
- Sponsor
- Alexandria University
Hematologic Malignancy, Neutropenia
Comparing Diosmin-Hesperidin and Loratadine to Prevent Bone Pain From G-CSF in Patients With Blood Cancers
This is a comparative interventional study to determine the best way to prevent G-CSF induced bone pain in patients with hematological malignancies (blood cancers).
- Conditions
- Hematologic Malignancy, Neutropenia, Bone Pain
- Trial name
- NCT07300735
- Testing
- Loratadine, Diosmin-Hesperidin, Loratadine + Diosmin-Hesperidin
- Where
- Egypt
- Volunteers
- 88 people
- Sponsor
- Alexandria University
Oral Leukoplakia
Topical Calcipotriol Versus Photodynamic Therapy in the Treatment of Oral Leukoplakia
The goal of this clinical trial is to learn if calcipotriol and photodynamic therapy are equally effective in treatment of leukoplakia or not.
- Trial name
- NCT07658508
- Testing
- Calcipotriol 0.005% gel, ALA mediated PDT
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Alexandria University
Healthcare Technology Adoption, Organizational Readiness
Organizational Readiness And Barriers To Adoption Of Female External Urinary Devices In Hospitals
This study aims to assess organizational readiness and explore perceived barriers and facilitators influencing the adoption of female external urinary collection devices among nurses in healthcare settings.
- Trial name
- NCT07656701
- Testing
- Exposure to Female External Urinary Collection Device Concept
- Where
- Egypt
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Alexandria University
Pancreatic Neoplasms, Pancreatic Cancer
Indocyanine Green-Guided Versus Standard Laparoscopic Distal Pancreatectomy for Pancreatic Body and Tail Lesions
Postoperative pancreatic fistula is the most important complication after laparoscopic distal pancreatectomy for tumors of the body and tail of the pancreas. It can cause infection, bleeding, longer hospital stay, and even death.
- Trial name
- ICG-LDP (NCT07656571)
- Testing
- ICG Fluorescence-Guided Laparoscopic Distal Pancreatectomy, Standard Laparoscopic Distal Pancreatectomy
- Where
- Egypt
- Volunteers
- 72 people
- Sponsor
- Alexandria University
Altered Passive Eruption of Teeth
Laser-Assisted Minimally Invasive Esthetic Crown Lengthening Using Flapless vs. Tunneled Flap Approach
Crown lengthening surgery is one of the most commonly performed periodontal procedures. Multiple techniques have been used throughout the years to overcome the postoperative pain and adverse outcomes that may be associated with…
- Trial name
- NCT07649226
- Testing
- laser assissted crown lengthening, surgical esthetic crown lengthening, Laser-assisted tunneled flap approach
- Where
- Egypt
- Volunteers
- 45 people
- Sponsor
- Alexandria University
Breast Cancer, ESPB
ESPB Versus Perioperative Iv Lidocaine Infusion on Proinflammatory Cytokines in Breast Cancer Surgeries
The present study aims to compare the effect of ESPB versus perioperative iv lidocaine infusion on proinflammatory cytokines in breast cancer surgeries.
- Conditions
- Breast Cancer, ESPB, Lidocaine Infusion
- Trial name
- ESPB (NCT07108959)
- Testing
- Erector spinae plane block (Group E), Lidocaine (drug)
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Alexandria University
Husband Attendance, Maternal-Neonatal Outcomes
Effect of Husband Attendance on Anesthesia Performance and Maternal-Neonatal Outcomes During Elective Cesarean Section Under Spinal Anesthesia
Family-centered perinatal care has become an integral component of modern obstetric practice, emphasizing emotional support and shared parental experiences during childbirth.
- Trial name
- NCT07641751
- Testing
- Husbands will be allowed to attend the cesarean section procedure, providing emotional support to their partners., Husbands will not be permitted to attend the cesarean section procedure
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Alexandria University