Clinical trials: sponsored by Anhui Medical University
Transcranial Direct Current Stimulation (tDCS), Breast Cancer Survivor
Transcranial Direct Current Stimulation for Cancer-related Cognitive Impairment in Breast Cancer Survivors
This study aims to evaluate the efficacy of transcranial direct current stimulation (tDCS) in improving cancer-related cognitive impairment (CRCI) in breast cancer survivors.
- Conditions
- Transcranial Direct Current Stimulation (tDCS), Breast Cancer Survivor, Cognitive Impairment
- Trial name
- NCT07083518
- Testing
- Anodal transcranial direct current stimulation
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Anhui Medical University
Acute Myocardial Infarction (AMI)
Stellate Ganglion Morphine Infiltration on Myocardial I/R Injury
The goal of this clinical trial is to investigate whether morphine modulates the functions of the stellate ganglion to reduce myocardial ischemia/reperfusion (I/R) injury in AMI patients.
- Trial name
- tSGM-AMI (NCT07023679)
- Testing
- Morphine
- Where
- 2 sites in China
- Volunteers
- 2,588 people
- Sponsor
- The Second Hospital of Anhui Medical University
ESCC, Lymph Node Metastasis
Lymph Node Metastasis in Early Esophageal Squamous Cell Carcinoma
This study aims to develop a predictive model using deep learning and radiomics to assess the likelihood of lymph node metastasis in patients with early-stage esophageal squamous cell carcinoma (ESCC).
- Conditions
- ESCC, Lymph Node Metastasis, Radiomics
- Trial name
- NCT07050576
- Testing
- The prediction model of lymph node metastasis in early esophageal squamous cell carcinoma
- Where
- China
- Volunteers
- 500 people
- Sponsor
- The First Affiliated Hospital of Anhui Medical University
Nephrolithiasis
The Application of Health Education Path Nursing Program
Objective: To explore the effect of health education pathway on self-management ability and quality of life of patients after percutaneous nephrolithotomy.
- Trial name
- NCT07047625
- Testing
- control group (Routine nursing), Experimental group （Health education path）
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Fuyang Affiliated Hospital of Anhui Medical University
Depressive Symptoms
An Evaluation of the Effect of Vitamin D Supplementation on Depressive Symptoms Among Chinese Early Adolescents
The goal of this randomized controlled clinical trial is to investigate the effects of vitamin D3 supplementation on depression in Chinese early adolescents with elevated depressive symptoms and vitamin D deficiency.
- Trial name
- NCT06247930
- Testing
- Vitamin D3, Mental health education
- Where
- 2 sites in China
- Volunteers
- 406 people
- Sponsor
- Anhui Medical University
Overweight or Obesity
Effectiveness of a Digital Behavioral Intervention Program for Overweight and Obese Patients
This study applied digital technology to a comprehensive lifestyle intervention strategy to design a digital behavioural intervention programme suitable for weight reduction in overweight obese infertile patients in China, and…
- Trial name
- NCT07045272
- Testing
- Experimental
- Volunteers
- 90 people
- Sponsor
- Anhui Medical University
Parkinson Disease, Transcranial Magenetic Stimualtion
The Efficacy and Safety of Precision REpetitive Transcranial Magnetic Stimulation in Alleviating Motor Symptom in Parkinson's Disease
Repetitive transcranial magnetic stimulation (rTMS) is a non-invasive and widely used neuromodulation technology. Small sample studies have shown that rTMS treatment can significantly improve the symptoms of Parkinson's…
- Conditions
- Parkinson Disease, Transcranial Magenetic Stimualtion, Supplementary Motor Area
- Trial name
- NCT06383247
- Testing
- transcranial magnetic stimulation
- Where
- China
- Volunteers
- 290 people
- Sponsor
- Anhui Medical University
Stroke, Cerebrovascular Disorders
Endovascular Treatment Beyond 24 Hours for Acute Ischemic Stroke Caused by Anterior Circulation Large Vessel Stenosis
Endovascular therapy (EVT) is currently recommended as the first-line treatment for patients with acute large vessel occlusion (LVO) in the anterior circulation within 24 hours of symptom onset.
- Conditions
- Stroke, Cerebrovascular Disorders, Brain Diseases, Nervous System Diseases
- Trial name
- EVT-BELATED (NCT06959199)
- Testing
- Endovascular Treatment, Best Medical Treatment
- Where
- China
- Volunteers
- 432 people
- Sponsor
- The Second Hospital of Anhui Medical University
Leukemia, Myeloid, Acute, Acute Myeloid Leukemia
Daunorubicin + Cytarabine + Venetoclax in de Novo AML
This study is a non-profit, prospective, single-center, open-label, controlled clinical trial aimed at evaluating the efficacy of the daunorubicin, cytarabine, and venetoclax (DAV) regimen in previously untreated adult AML…
- Trial name
- NCT06697327
- Testing
- (Daunorubicin, Cytarabine, Venetoclax), (Daunorubicin, Cytarabine)
- Where
- China
- Volunteers
- 94 people
- Sponsor
- Anhui Medical University
Central Venous Catheterization
Head-mounted Display for Central Venous Catheterization
Head-mounted displays (HMD) in medical practice are current research topics. The goal of this clinical trial is to learn if HMD would improve the safety and efficacy in ultrasound-guided central venous catheterization.
- Trial name
- NCT06469034
- Testing
- conventional ultrasound, Head-mounted display ultrasound
- Where
- China
- Volunteers
- 124 people
- Sponsor
- The Second Hospital of Anhui Medical University
Post Stroke Depression, Stroke
Observation on the Therapeutic Effect of Low-Intensity Transcranial Ultrasound Stimulation Combined With Upper Limb Virtual Reality Training on Post-Stroke Depression
Abstract: objective:To study whether post-stroke depression can be improved through low-intensity transcranial ultrasound stimulation combined with upper limb virtual reality training, explore its possible mechanisms, and provide…
- Trial name
- NCT06957340
- Testing
- Low-Intensity Transcranial Ultrasound Stimulation
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Anhui Medical University
Chronic Insomnia Disorder
Changed Serum Levels of Sirtuin1 and Sirtuin3 and Their Correlations With Sleep Quality and Cognitive Function in the Patients With Chronic Insomnia Disorder
The goal of this study is to explore whether mitochondrial dysfunction exists in patients with chronic insomnia disorder. The main questions it aims to answer are : Do serum mitochondrial markers change in patients with chronic…
- Trial name
- SIRT1 SIRT3 (NCT06955299)
- Where
- China
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Chaohu Hospital of Anhui Medical University
Alzheimer Disease, Transcranial Magnetic Stimulation
Effect of Neuronavigated Theta-Burst Transcranial Magnetic Stimulation (TBS) for Early Alzheimer's Disease
Comparison of the therapeutic effects of two neuronavigated theta-pulse transcranial magnetic stimulation in patients with Alzheimer's disease and their underlying neural mechanisms
- Conditions
- Alzheimer Disease, Transcranial Magnetic Stimulation, Neuronavigation
- Trial name
- NCT06524817
- Testing
- transcranial magnetic stimulation
- Where
- China
- Sponsor
- Anhui Medical University
Cholangiopancreatography, Endoscopic Rretrograde, Post-ERCP Pancreatitis
Early Pancreatic Stent Placement for Preventing PEP
Our aim is to compare early versus late pancreatic stent placement in preventing PEP among patients with naive papilla. The EVL trial will provide essential answers regarding the optimal timing of prophylactic pancreatic stent…
- Trial name
- EVL (NCT06250803)
- Testing
- early pancreatic stent placement (EPSP)
- Where
- 2 sites in China
- Volunteers
- 768 people
- Sponsor
- The First Affiliated Hospital of Anhui Medical University
Transcranial Direct Current Stimulation, Parkinson Disease
An Open-label Study on the Clinical Efficacy of tDCS Intervention in PD
To demonstrate that intervention targeting the primary motor area (M1) using transcranial Direct Current Stimulation can improve sleep symptoms in patients with Parkinson's disease.
- Conditions
- Transcranial Direct Current Stimulation, Parkinson Disease, Primary Left Motor Cortex
- Trial name
- NCT06566313
- Testing
- transcranial Direct Current Stimulation
- Where
- China
- Volunteers
- 17 people
- Sponsor
- Anhui Medical University
Schizophrenia, Transcranial Magnetic Stimulation
Personalized Dual-target RTMS for Patients with Refractory Schizophrenia
The goal of this clinical trial is to evaluate the efficacy of personalized dual-target rTMS for treating patients with refractory schizophrenia and to investigate its underlying neural mechanisms using functional MRI.
- Conditions
- Schizophrenia, Transcranial Magnetic Stimulation, Functional Magnetic Resonance Imaging (fMRI)
- Trial name
- NCT06732817
- Testing
- Active rTMS was administered using a transcranial magnetic stimulator (Rapid2; MagStim).
- Where
- China
- Volunteers
- 20 people
- Sponsor
- Anhui Medical University
Smartphone Addiction
WeChat Intervention for Smartphone Addiction in College Students: A Randomized Trial
The goal of this clinical trial is to assess the effectiveness of an intervention based on the Information-Motivation-Behavioral Skills (IMB) model to treat smartphone addiction in college students.
- Trial name
- smartphone (NCT06730152)
- Testing
- WeChat Intervention Based on the IMB Model
- Where
- China
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- Anhui Medical University
Mitochondrial Diseases
Establishment of Reproductive Cohort and Prediction Model of Genetic Counseling for Mitochondrial Genetic Diseases
The goal of this observational study is to provide a reference for clinicians to conduct genetic counseling and carry out preimplantation genetic testing of mitochondrial patients.
- Trial name
- NCT06450964
- Testing
- Biological samples such as blood, urine, oral epithelial cells and nails of carriers were collected, and the mitochondrial DNA mutation heterogeneity level was determined.
- Where
- China
- Volunteers
- 600 people
- Sponsor
- Anhui Medical University
Parkinson Disease, Olfactory Disorder
The Efficacy of Olfactory Training Intervention on Olfactory and Other Non-motor Symptoms in PD
To explore the efficacy of olfactory training on olfactory and other non-motor symptoms in PD.
- Conditions
- Parkinson Disease, Olfactory Disorder, Olfactory Training
- Trial name
- NCT06607653
- Testing
- Olfactory training
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Anhui Medical University
Parkinson Disease, Transcranial Magenetic Stimualtion
The Efficacy of Repetitive Transcranial Magnetic Stimulation in Parkinson's Disease：A Randomized, Double-blind, Multicenter, Placebo-controlled Trial
Repetitive transcranial magnetic stimulation (rTMS) is a non-invasive and widely used neuromodulation technology. Small sample studies have shown that rTMS treatment can significantly improve the symptoms of Parkinson's…
- Conditions
- Parkinson Disease, Transcranial Magenetic Stimualtion, Supplementary Motor Area
- Trial name
- NCT06583278
- Testing
- transcranial magnetic stimulation
- Volunteers
- 312 people
- Sponsor
- Anhui Medical University