Clinical trials: sponsored by Beijing Chao Yang Hospital
Chronic Obstructive Pulmonary Disease (COPD), Asthma (Diagnosis)
Construction and Validation of an Impulse Oscillometry (IOS)-Based Platform for Screening, Diagnosis, and Management of Chronic Airway Diseases
This is a multicenter, observational study aiming to construct and validate an Impulse Oscillometry (IOS)-based platform for the screening, diagnosis, and management of chronic airway diseases (COPD and asthma).
- Trial name
- NCT07910409
- Where
- China
- Volunteers
- 2,800 people, healthy volunteers welcome
- Sponsor
- Beijing Chao Yang Hospital
Sedation, Analgesia Assessment
A Prospective Multicenter Registry Study of Sedation and Analgesia in Critically Ill Patients
Sedation and analgesia are essential components of comprehensive care for intensive care unit (ICU) patients, particularly those receiving invasive mechanical ventilation, undergoing invasive procedures, or experiencing pain…
- Conditions
- Sedation, Analgesia Assessment, ICU
- Trial name
- NCT07885930
- Testing
- Not applicable- observational study
- Where
- China
- Volunteers
- 2,000 people
- Sponsor
- Beijing Chao Yang Hospital
Pulmonary Nodules, Early Detection of Cancer
Diagnostic Performance of an AI-Based Multi-Omics Model for Early Lung Cancer
This is a prospective, multicenter observational cohort study for patients with lung nodules suspicious for early-stage lung cancer.
- Conditions
- Pulmonary Nodules, Early Detection of Cancer, Lung Neoplasms
- Trial name
- NCT07882628
- Where
- 8 sites in China
- Volunteers
- 1,050 people
- Sponsor
- Beijing Chao Yang Hospital
Pulmonary Disease, Chronic Obstructive (COPD), Chronic Respiratory Failure With Hypercapnia
RESET-COPD Cohort: Real-Time Monitoring and Early Warning in COPD Patients Receiving Home NPPV
This is a multicenter prospective cohort study designed to develop and validate a multisensor-based real-time monitoring and intelligent early warning model for acute exacerbations in patients with chronic obstructive pulmonary…
- Conditions
- Pulmonary Disease, Chronic Obstructive (COPD), Chronic Respiratory Failure With Hypercapnia, Noninvasive Ventilation
- Trial name
- RESET-COPD (NCT07701096)
- Testing
- Not applicable- observational study
- Where
- China
- Volunteers
- 250 people
- Sponsor
- Beijing Chao Yang Hospital
Type 2 Diabetes
Efficacy of Lactobacillus Paracasei LC19 on Type 2 Diabetes
This is a randomized, double-blind, placebo-controlled clinical trial. The objective of this trial is to determine whether Lactobacillus paracasei LC19 supplementation has a positive effect on glucose lowering in patients with…
- Trial name
- NCT06639425
- Testing
- Lactobacillus paracasei LC19 supplementation
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Beijing Chao Yang Hospital
Sepsis, Acute Kidney Injury
Immune Evaluation for Postoperative Sepsis-AKI
This prospective, multicenter, observational cohort study plans to enroll over 800 patients with postoperative sepsis from the ICUs of two tertiary hospitals in Beijing.
- Trial name
- NCT07811544
- Testing
- Not applicable- observational study
- Where
- China
- Volunteers
- 800 people
- Sponsor
- Beijing Chao Yang Hospital
General Anesthesia-Induced Altered Consciousness
Brain Activity and Changes in Consciousness During General Anesthesia
This study aims to investigate how general anesthetics alter brain activity and consciousness across different age groups. The study will evaluate four anesthetic agents with different mechanisms of action: propofol, remimazolam…
- Trial name
- NCT07836205
- Testing
- Propofol (Group P), Remimazolam group, Esketamine group
- Where
- China
- Volunteers
- 320 people, healthy volunteers welcome
- Sponsor
- Beijing Chao Yang Hospital
Chronic Obstructive Pulmonary Disease (COPD), Multimorbidities
IMPACT COPD Cohort (China)
Chronic obstructive pulmonary disease (COPD) is a major chronic respiratory condition with high prevalence of multimorbidity. COPD and comorbidities interact dynamically, contributing to symptom fluctuation, acute exacerbations…
- Trial name
- IMPACT (NCT07382986)
- Testing
- Not applicable- observational study
- Where
- 4 sites in China
- Volunteers
- 10,000 people
- Sponsor
- Beijing Chao Yang Hospital
Coronary Artery Disease, Plaque
PCCT-Defined High-Risk Plaque and Future Coronary Events: The PREDICT Study
This prospective cohort study aims to determine whether high-risk coronary plaques identified by novel Photon-Counting Detector CT (PCCT) independently predict future major adverse cardiovascular events (MACE).
- Conditions
- Coronary Artery Disease, Plaque, Photon-Counting Computed Tomography
- Trial name
- PREDICT (NCT07822737)
- Where
- China
- Volunteers
- 500 people
- Sponsor
- Beijing Chao Yang Hospital
Postoperative Pain
Electroencephalogram Changes Induced by Transcutaneous Electrical Acupoint Stimulation
A total of 90 subjects underwent abdominal surgery under general anesthesia at Chaoyang Hospital in Beijing. The subjects were divided into a percutaneous acupoint electrical stimulation group and a control group.
- Trial name
- NCT07819630
- Testing
- Transcutaneous electrical acupoint stimulation
- Where
- China
- Volunteers
- 90 people
- Sponsor
- Beijing Chao Yang Hospital
ARDS (Moderate or Severe)
Transpulmonary Pressure-guided Mechanical Ventilation Strategy in Right Ventricular Protection in Patients With ARDS
To verify whether the transpulmonary pressure-guided mechanical ventilation strategy can reduce right ventricular involvement, especially the incidence of acute cor pulmonale (ACP), in patients with moderate to severe ARDS…
- Trial name
- NCT07490925
- Testing
- Transpulmonary pressure guided mechanical ventilation strategy
- Where
- China
- Volunteers
- 180 people
- Sponsor
- Beijing Chao Yang Hospital
ECMO
A Novel Strategy of ECMO Management Using Nafamostat for Regional Combined With Low Intensity Systematic Anticoagulation
ECMO is widely used in patients with refractory respiratory and/or circulatory failure.The data shows that the incidence of bleeding and thrombotic events is still above 40%,and it is closely related to the increase in mortality…
- Trial name
- NCT06676085
- Testing
- Nafamostat, Heparin
- Where
- China
- Volunteers
- 140 people
- Sponsor
- Beijing Chao Yang Hospital
Anesthesia
Design and Development of Multi-modal Intelligent Anesthesia Monitoring System
This project integrates the characteristics of electroencephalo-graph（EEG）, cerebral oxygen, blood pressure, heart rate, etc., based on nonlinear theory and multi-modal monitoring system suitable for domestic patients, taking…
- Trial name
- NCT06317025
- Testing
- Multi-modal Intelligent Anesthesia Monitoring System
- Where
- China
- Volunteers
- 330 people
- Sponsor
- Beijing Chao Yang Hospital
Peripheral Pulmonary Lesions (PPLs), Pulmonary Nodules
Comparative Study of Rotational Cryobiopsy Needle and Automated Biopsy Needle in Transthoracic Biopsy Diagnosing Peripheral Pulmonary Lesions
This study aims to systematically compare the diagnostic efficacy, specimen quality, and complication rates of the cryobiopsy needle technique（CassiII rotational core biopsy） versus the automated biopsy technique in the biopsy of…
- Trial name
- NCT07772479
- Testing
- CassiII rotational core biopsy, Automated biopsy
- Where
- China
- Volunteers
- 308 people
- Sponsor
- Beijing Chao Yang Hospital
Sepsis
Immunity in Critical Sepsis
Sepsis is a life-threatening organ dysfunction caused by a dysregulated host immune response to infection, and remains the leading cause of death in critical care medicine worldwide.
- Trial name
- NCT07770347
- Testing
- Individualized anti-infective therapy, Individualized immunomodulatory therapy, Individualized organ function support therapy
- Where
- China
- Volunteers
- 2,400 people
- Sponsor
- Beijing Chao Yang Hospital
Stroke, Upper Extremity Motor Function
Invasive Vagus Nerve Stimulation Paired With Rehabilitation After Stroke
This study evaluated the feasibility, safety, and preliminary functional outcomes of invasive vagus nerve stimulation (iVNS) paired with upper-limb rehabilitation in participants with chronic stroke-related upper-limb motor…
- Conditions
- Stroke, Upper Extremity Motor Function, Intracerebral Hemorrhage
- Trial name
- VNS-Stroke (NCT07736573)
- Testing
- Invasive Vagus Nerve Stimulation
- Where
- China
- Volunteers
- 12 people
- Sponsor
- Beijing Chao Yang Hospital
Acute Ischemic Stroke
Hyperbaric Oxygen After Stroke Thrombectomy: A Multicenter Randomized Trial on Safety and Efficacy
1. The goal of this clinical trial is to evaluate the efficacy and safety of hyperbaric oxygen (HBO)in stroke patients after endovascular treatment 2.
- Trial name
- NOTICE-1 (NCT07049692)
- Testing
- Hyperbaric Oxygen Therapy, Conventional therapy group
- Where
- 2 sites in China
- Volunteers
- 424 people
- Sponsor
- Beijing Chao Yang Hospital
Sepsis
Sepsis in Critically Ill Patients
Sepsis is a life-threatening organ dysfunction caused by a dysregulated host immune response to infection, and remains the leading cause of death in critical care medicine worldwide.
- Trial name
- NCT07707622
- Testing
- Not applicable- observational study
- Where
- China
- Volunteers
- 2,400 people
- Sponsor
- Beijing Chao Yang Hospital
Ischemic Heart Failure
FAPl Imaging Assessment of Revascularization Outcome in Ischemic Heart Failure
Ischemic heart failure (IHF) is the final stage of coronary heart disease. Coronary revascularization is an important treatment method for IHF, but it has high perioperative risks and not all patients can benefit from it.
- Trial name
- FARO (NCT07657650)
- Testing
- PCI (ercutaneous coronary intervention) and CABG (coronary artery bypass grafting, commonly known as heart bypass surgery)
- Where
- China
- Volunteers
- 122 people
- Sponsor
- Beijing Chao Yang Hospital
Rectal Cancer
SIS-Reinforced vs. Conventional Anastomosis for Mid-to-Low Rectal Cancer: A Multicenter RCT on Anastomotic Leak
The goal of this clinical trial is to learn whether using a reinforcing material called SIS (small intestinal submucosa) during bowel connection after rectal cancer surgery can help prevent anastomotic leakage-a serious…
- Trial name
- NCT07209787
- Testing
- SIS-reinforced anastomosis
- Where
- China
- Volunteers
- 966 people
- Sponsor
- Beijing Chao Yang Hospital