Clinical trials: sponsored by Beijing Chao Yang Hospital
Acute Kidney Injury
Acute Kidney Injury in Critically Ill Patients
Acute kidney injury (AKI) in critically ill patients is characterized by high incidence, delayed diagnosis and treatment, and high mortality. Early identification and precision management are key to improving prognosis.
- Trial name
- NCT07653321
- Testing
- Not applicable- observational study
- Where
- China
- Volunteers
- 23,600 people
- Sponsor
- Beijing Chao Yang Hospital
Septic Shock
Adaptive Blood Purification for the Treatment of Patients With Septic Shock
There is a lack of evidence in the efficacy of extracorporeal blood purification (EBP) to reduce the mortality rate in septic shock.
- Trial name
- NCT06692036
- Testing
- Adaptive Blood Purification (ABP)
- Where
- China
- Volunteers
- 276 people
- Sponsor
- Beijing Chao Yang Hospital
Cerebral Infarction, Thrombolysis
Early Low-dose ASpirin Use After Intravenous Thrombolysis for Acute Ischemic Cerebral Infarction（ELASTIC）
This study evaluates whether early administration of low-dose aspirin (100mg) at 2 hours post-intravenous thrombolysis, compared to the standard timing of 24 hours, improves functional outcomes in patients with acute ischemic…
- Trial name
- ELASTIC (NCT07563673)
- Testing
- Aspirin (Early, 2h), Aspirin (Standard, 24h)
- Where
- China
- Volunteers
- 210 people
- Sponsor
- Beijing Chao Yang Hospital
Lung Cancer, Venous Thromboembolism
Development and Application of a Thrombosis Risk Prediction Model in Lung Cancer Patients Treated With Immune Checkpoint Inhibitors
The purpose of this observational study is to explore the incidence, risk factors, and relationship with therapeutic outcomes of VTE (venous thromboembolism) and ATE (arterial thromboembolism) associated with immune checkpoint…
- Conditions
- Lung Cancer, Venous Thromboembolism, Arterial Thromboembolism, Immune Checkpoint Inhibitors (ICIs)
- Trial name
- NCT06950697
- Where
- 5 sites in China
- Volunteers
- 2,400 people
- Sponsor
- Beijing Chao Yang Hospital
Type 2 Diabetes
Efficacy Heterogeneity of Lactobacillus Paracasei LC19 on Type 2 Diabetes
This is a single-arm study to investigate the heterogeneity of glycemic response to Lactobacillus paracasei LC19 in patients with newly diagnosed type 2 diabetes.
- Trial name
- NCT07520305
- Testing
- Lactobacillus paracasei LC19 Intervention
- Where
- China
- Volunteers
- 70 people
- Sponsor
- Beijing Chao Yang Hospital
Pneumonia
A Clinical Cohort Study of Pneumonia in Respiratory Intensive Care Unit
From 2003 when Severe Acute Respiratory Syndromes (SARS) appeared，many new types of respiratory viruses emerge in endlessly. Therefore, the epidemiology and the clinical character has changed quietly, especially severe pneumonia.
- Trial name
- NCT02738645
- Testing
- pneumonia
- Where
- China
- Volunteers
- 800 people
- Sponsor
- Beijing Chao Yang Hospital
Acute Respiratory Distress Syndrome, Acute Cor Pulmonale
Transpulmonary Pressure in Right Ventricle Protection of ARDS
To compare the effect between mechanical ventilation strategy guided by transpulmonary pressure and tranditional lung protective ventilation strategy in acute respiratory distress syndrome for right ventricle protection.
- Trial name
- NCT05629832
- Testing
- mechanical ventilation strategy guided by transpulmonary pressure
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Beijing Chao Yang Hospital
Asthma (Diagnosis), Chronic Obstructive Pulmonary Disease (COPD)
Investigation and Classification of Treatable Traits in Patients With Chronic Airway Diseases
This research study focuses on chronic airway diseases, such as Chronic Obstructive Pulmonary Disease (COPD) and asthma. These conditions make it difficult for patients to breathe, but breathing difficulty (dyspnea) is often…
- Conditions
- Asthma (Diagnosis), Chronic Obstructive Pulmonary Disease (COPD), Chronic Airway Diseases
- Trial name
- NCT07472738
- Testing
- Comprehensive Clinical Assessment
- Where
- China
- Volunteers
- 950 people, healthy volunteers welcome
- Sponsor
- Beijing Chao Yang Hospital
Diagnosis
The Study of ENB With Ultra-thin Cryobiopsy in the Diagnosis of Peripheral Pulmonary Nodules
To investigate the safety and efficacy of ultrafine cryoprobe biopsy by electromagnetic navigation bronchoscopy compared with biopsy forceps in the diagnosis of peripheral pulmonary nodules in a national multicenter randomized…
- Trial name
- NCT07326072
- Testing
- Cryobiopsy, Forceps biopsy
- Where
- China
- Volunteers
- 228 people
- Sponsor
- Beijing Chao Yang Hospital
Obesity
The Effect of Semaglutide on the Intestinal Flora in Obesity
For obese individuals, semaglutide treatment was adopted. By using multi-omics techniques such as fecal metagenomic sequencing and based on in vitro strain screening platforms, the effects and specific mechanisms of semaglutide…
- Trial name
- NCT07323134
- Testing
- Semaglutide Injection
- Volunteers
- 40 people
- Sponsor
- Beijing Chao Yang Hospital
Acute Hypoxemic Respiratory Failure, High-flow Nasal Cannula Oxygen
Modified HFNC Therapy for ARF Patients Undergoing Flexible Bronchoscopy
Acute respiratory failure (AFR) is a serious condition that requires prompt and appropriate intervention to prevent further deterioration and improve outcomes.
- Trial name
- NCT05759832
- Testing
- Modified HFNC oxygen therapy, Non-rebreathing reservoir mask
- Where
- 2 sites in China
- Volunteers
- 160 people
- Sponsor
- Beijing Chao Yang Hospital
Sensitivity to Thyroid Hormones, Metabolic Parameters
Effects of Intermittent Fasting on Fatty Liver Disease
Eighty subjects with FLD were recruited from the endocrinology clinic at Beijing Chao-yang Hospital. All of the following inclusion criteria needed to be met: hepatic fat content (HFC) were upper 5.0% evaluated by upper abdominal…
- Conditions
- Sensitivity to Thyroid Hormones, Metabolic Parameters, in Patients With FLD
- Trial name
- NCT04795973
- Testing
- 5:2 intermittent fasting
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Beijing Chao Yang Hospital
Asthma
The Study About the Identification of Treatable Traits of Severe Asthma and the Construction of Personalized Treatment System
Severe asthma is a complex and heterogeneous disease. Patients with severe asthma can present with different types of airway inflammation, and are often accompanied by a variety of comorbidities and risk factors.
- Trial name
- NCT07136025
- Testing
- Individualized cluster management, Routine asthma treatment
- Where
- 10 sites in China
- Volunteers
- 200 people
- Sponsor
- Beijing Chao Yang Hospital
Acute Respiratory Distress Syndrome, Extracorporeal Membrane Oxygenation
Effect of Transpulmonary MP on Prognosis of Patients With Severe ARDS Treated With VV-ECMO
Venovenous extracorporeal membrane oxygenation (VV-ECMO) is a salvage treatment for severe acute respiratory distress syndrome (ARDS).
- Conditions
- Acute Respiratory Distress Syndrome, Extracorporeal Membrane Oxygenation, Mechanical Power, Transpulmonary Mechanical Power
- Trial name
- NCT06062212
- Testing
- Transpulmonary pressure
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Beijing Chao Yang Hospital
Acute Respiratory Distress Syndrome
Early PP Monitored by EIT in Patients With ARDS
Acute Respiratory Distress Syndrome (ARDS) is a syndrome characterized by respiratory distress and refractory hypoxemia caused by pulmonary and extra-pulmonary factors.
- Trial name
- NCT05822869
- Testing
- EIT-guided mechanical ventilation strategy, Lung protective ventilation group
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Beijing Chao Yang Hospital
Extracorporeal Membrane Oxygenation, Membrane Lung Function
Evaluation of Membrane Lung Function in High-altitude Regions
Over the last 20 years, extracorporeal membrane oxygenation (ECMO) has been used to support adult patients with respiratory or cardiac failure who are unlikely to survive conventional treatment methods.
- Conditions
- Extracorporeal Membrane Oxygenation, Membrane Lung Function, High Altitude
- Trial name
- NCT06152744
- Testing
- Monitoring membrane lung function at different altitudes
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Beijing Chao Yang Hospital
Acute Respiratory Distress Syndrome, Prone Position
Improvement of ARDS Ventilation-perfusion Matching by Prone Positioning Assessed by EIT
Acute Respiratory Distress Syndrome (ARDS) is a highly lethal disease with limited treatment options. In recent years, prone position ventilation has been shown to improve the mortality rate and lung injury of ARDS patients by…
- Conditions
- Acute Respiratory Distress Syndrome, Prone Position, Electrical Impedance Tomography
- Trial name
- NCT05765760
- Where
- China
- Volunteers
- 77 people
- Sponsor
- Beijing Chao Yang Hospital
Cardiovascular Surgery, Perioperative Neurocognitive Disorders
Exploring the Predictive Value of Electroencephalography Features in Perioperative Neurocognitive Disorders Following Cardiovascular Surgery
To explore the predictive value of Electroencephalography features in Perioperative Neurocognitive Disorders in patients undergoing cardiovascular surgery under general anesthesia
- Trial name
- NCT06692309
- Testing
- cardiovascular surgery
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Beijing Chao Yang Hospital
Fibrosing Mediastinitis, Pulmonary Hypertension
Study on the Treatment of Nonthrombotic Obstructive Pulmonary Hypertension
Through a randomized controlled trial (RCT) design, this study aiming to evaluated the efficacy and safety of rituximab lymph node injection combined with pulmonary vascular interventional therapy in treating fibrosing…
- Trial name
- ACCT-NOPH (NCT06980584)
- Testing
- Rituximab Lymph Node Injection Combined with Pulmonary Vascular Intervention, Pulmonary Vascular Interventional Therapy
- Where
- China
- Volunteers
- 48 people
- Sponsor
- Beijing Chao Yang Hospital
PAH, CTEPH
Effects of Pulmonary Rehabilitation on Quality of Life and Health in Pulmonary Arterial Hypertension Patients
Pulmonary hypertension (PH) is a major global health concern, affecting approximately 1% of the world's population. With global aging and increased life expectancy, its incidence continues to rise.
- Trial name
- EPRQoL-PAH (NCT06973382)
- Testing
- Comprehensive Pulmonary Rehabilitation Program, Standard Pulmonary Rehabilitation
- Volunteers
- 84 people
- Sponsor
- Beijing Chao Yang Hospital