Clinical trials: sponsored by Beijing Chao Yang Hospital
Elderly
A Individualized Physical Function Improvement Program for Frailty Elderly Using Goal Attainment Scaling (GAS) as Evaluation Method: Protocol for a Randomized Controlled Trial
Frailty refers to the age-related decline in physiological functions，that is associated with adverse outcomes. Frailty is a dynamic reversible state, that requires a comprehensive individualized management.
- Trial name
- NCT06919575
- Testing
- Multicomponent frailty intervention
- Volunteers
- 160 people
- Sponsor
- Beijing Chao Yang Hospital
Postoperative Nausea and Vomiting, Opioid Use
Effect of Opioid-free Anesthesia on PostOperative Nausea and Vomiting in Patients Undergoing Video-assisted Thoracoscopic Surgery
This study aimed to verify whether an Opioid-free Anesthesia (OFA) could effectively reduce the incidence of PONV after thoracoscopic-assisted surgery compared with standard general anesthesia (OA) regimens.
- Conditions
- Postoperative Nausea and Vomiting, Opioid Use, Thoracic Diseases
- Trial name
- OFA-PONV (NCT05411159)
- Testing
- Opioid-Free Anesthesia (OFA), Standard general anesthesia (OA)
- Where
- China
- Volunteers
- 168 people
- Sponsor
- Beijing Chao Yang Hospital
Asthma
Treatable Traits of Severe Asthma
Severe or uncontrolled asthma is a complex heterogeneous disease, in which patients may exhibit different types of airway inflammation and often accompany multiple comorbidities and risk factors.
- Trial name
- NCT06811740
- Testing
- Individualized cluster management, Routine asthma treatment
- Where
- 3 sites in China
- Volunteers
- 160 people
- Sponsor
- Beijing Chao Yang Hospital
Obesity
Semaglutide's Weight Loss Effects in Obesity
This is a non-randomized, concurrent, parallel-controlled clinical trial. The objective of this trial is to determine the relationship between weight loss responsiveness to semaglutide in obese patients and their gut microbiota.
- Trial name
- NCT06825793
- Testing
- Semaglutide Subcutaneous Injection
- Volunteers
- 56 people
- Sponsor
- Beijing Chao Yang Hospital
Periodontitis
Er:YAG Laser and Air Polishing Application in Periodontal Treatment
Periodontitis (gum disease) is an infection of the gums that can lead to tooth loss. In recent years, many types of dental lasers or other devices have been used for the non-surgical treatment of periodontal diseases.
- Trial name
- NCT06574802
- Testing
- ERL + air polishing, ERL
- Where
- China
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Beijing Chao Yang Hospital
Early-Stage Lung Cancer, NSCLC
A Study Developing a Non-invasive Urine-based Proteomic Model for Early Lung Cancer Detection.
Brief Summary: The goal of this observational study is to develop a non-invasive urine proteomic diagnostic model to improve early-stage lung cancer detection.
- Conditions
- Early-Stage Lung Cancer, NSCLC, Pulmonary Nodule
- Trial name
- UPD-LC (NCT06733311)
- Where
- China
- Volunteers
- 480 people
- Sponsor
- Beijing Chao Yang Hospital
Sleeve Gastrectomy, Pre-cardial Fat Pad
Preserving the Pre-cardial Fat Pad During Sleeve Gastrectomy on Postoperative Gastroesophageal Reflux
Gastroesophageal reflux disease (GERD) is one of the most common chronic conditions that can affect one's quality of life. Laparoscopic sleeve gastrectomy (LSG) has become a popular technique and currently is the most frequently…
- Conditions
- Sleeve Gastrectomy, Pre-cardial Fat Pad, Excessive Weight Loss, Total Weight Loss
- Trial name
- Pad and SG (NCT06732661)
- Testing
- Preserve pre-cardial fat pad, Dissect pre-cardial fat pad
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Beijing Chao Yang Hospital
Acute Exacerbation of Chronic Obstructive Pulmonary Disease
Impact of HI-NPPV Vs LI-NPPV on Tolerance Among AECOPD Patients
To determine whether high-intensity NPPV, compared with low-intensity NPPV, could have an effect on the subjective tolerance in patients with an AECOPD and hypercapnia.
- Trial name
- NCT06692023
- Testing
- High-intensity NPPV, Low-intensity NPPV
- Where
- China
- Volunteers
- 20 people
- Sponsor
- Beijing Chao Yang Hospital
Respiratory Distress Syndrome, Adult
Early Use of Prone Position in ECMO for Severe ARDS
Venovenous extracorporeal membrane oxygenation (VV-ECMO) is widely used in the salvage treatment of critical acute respiratory distress syndrome (ARDS).
- Trial name
- NCT04139733
- Testing
- Prone positon, Supine positon
- Where
- China
- Volunteers
- 160 people
- Sponsor
- Beijing Chao Yang Hospital
Combined Spinal-epidural Anesthesia
Relationship Between ANI, Anxiety, and Pain in Conscious Hernia Patients Undergoing CSEA
Analgesia Nociception Index can be used to detect noxious stimulation during general anesthesia.The aim of this study is to observe ANI under combined spinal epidural anesthesia procedures in conscious hernia patients.
- Trial name
- NCT05053633
- Testing
- Combined spinal epidural anesthesia
- Where
- China
- Volunteers
- 24 people
- Sponsor
- Beijing Chao Yang Hospital
Anesthesia Recovery Period
Postoperative Quality of Recovery After General Anesthesia With Remimazolam
126 patients undergoing general anesthesia for elective surgery in Beijing Chaoyang Hospital were selected. In the intervention group, anesthesia was induced with remimazolam besylate at a rate of 6mg/min; Anesthesia was…
- Trial name
- NCT06332157
- Testing
- Remimazolam besylate, Propofol Injection Emulsion
- Volunteers
- 126 people
- Sponsor
- Beijing Chao Yang Hospital
Remimazolam, Anesthesia Awareness
The Effect of Wavelet Index in Monitoring the Sedation Depth of Remimazolam Besylate
To explore the sedative effect of remimazolam in patients undergoing spinal anesthesia without pain stimulation. Both the Modified Observer's Assessment of Alertness/Sedation (MOAA/S) and the Wavelet index (WLi) were used to…
- Conditions
- Remimazolam, Anesthesia Awareness, Sedative, Hypnotic, or Anxiolytic Withdrawal
- Trial name
- NCT06427785
- Testing
- Remimazolam besylate
- Volunteers
- 30 people
- Sponsor
- Beijing Chao Yang Hospital
Using Functional Lung MRI to Explore Pulmonary Perfusion Changes in Patients With Pulmonary Fibrosis and Emphysema Syndrome
Magnetic Resonance Lung Function Imaging Study of Pulmonary Fibrosis Combined With Emphysema Syndrome
This study intends to use magnetic resonance pulmonary function imaging technology to explore imaging markers for early diagnosis of patients with CPFE.
- Trial name
- NCT06431555
- Testing
- MRI
- Where
- China
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Beijing Chao Yang Hospital
Respiratory Failure
Safety and Efficacy of Argatroban Applicated in Anticoagulation of V-V ECMO
Unfractionated heparin is most common in the anticoagulation management of V-V ECMO. However, many side effects of unfractionated heparin, such as HIT, antithrombin deficiency, etc seriously affects the prognosis of patients.
- Trial name
- NCT04925167
- Testing
- Argatroban, unfractionated heparin
- Where
- China
- Volunteers
- 20 people
- Sponsor
- Beijing Chao Yang Hospital
Mechanical Ventilation Complication, Weaning Failure
A Modified Cuff Leak Test and Reintubation in Mechanically Ventilated Patients
We hypothesized that the accuracy of the modified cuff leak test in predicting re-intubation in tracheal intubated patients is better than that of the conventional balloon leak test, thereby further reducing the re-intubation…
- Conditions
- Mechanical Ventilation Complication, Weaning Failure, Airway Obstruction
- Trial name
- NCT05550220
- Testing
- Cuff Leak Test
- Where
- China
- Volunteers
- 586 people
- Sponsor
- Beijing Chao Yang Hospital
M-protein Related Cardiac Disease
Combination of Daratumumab and BD Regimen and Dapagliflozin in the Treatment of M-protein Related Cardiac Disease
It is expected to include 40 patients with M-protein related cardiac disease. The treatment medication for enrolled patients must comply with the treatment regimen of Daratumumab + Bortezomib + Dexamethasone.
- Trial name
- NCT06297681
- Testing
- Daratumumab + Bortezomib + Dexamethasone + Dapagliflozin
- Volunteers
- 40 people
- Sponsor
- Beijing Chao Yang Hospital
Acute Exacerbation of Chronic Obstructive Pulmonary Disease
High-Intensity vs Low-Intensity NPPV in Patients With an AECOPD: The HAPPEN Trial
To determine whether high-intensity NPPV, compared with low-intensity NPPV, could reduce the need for endotracheal intubation during hospitalization in patients with an AECOPD and hypercapnia.
- Trial name
- NCT02985918
- Testing
- High-intensity NPPV, Low-intensity NPPV
- Where
- 31 sites in China
- Volunteers
- 300 people
- Sponsor
- Beijing Chao Yang Hospital
Acute Ischemic Stroke
Effect of Postoperative Prolonged Sedation With Dexmedetomidine After Successful Reperfusion With EVT on Long-term Prognosis in Patients With AIS (PPDET)
Dexmedetomidine can attenuate the activity of the sympathetic nervous system under stress response and improve ischemia-reperfusion injury.
- Trial name
- NCT04916197
- Testing
- Dexmedetomidine prolonged sedation, 0.9% saline
- Where
- China
- Volunteers
- 368 people
- Sponsor
- Beijing Chao Yang Hospital
End Stage Liver DIsease, Liver Transplantation
Effect of Transfusion of Plasma on Endothelial During Liver Transplantation
To study the effects of plasma transfusionon during liver transplantation on endothelial condition and short-term outcome in patients with end-stage liver disease.
- Trial name
- NCT04107883
- Testing
- fresh frozen plasma, blood sample
- Where
- China
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Beijing Chao Yang Hospital
Type 2 Diabetes
Sitagliptin for the Treatment of Type 2 Diabetes
Patients newly diagnosed with T2D will be recruited and will receive sitagliptin treatment for 3 months. The gut microbiome of the participants before and after the treatment and the effectiveness of sitagliptin treatment on type…
- Trial name
- NCT04495881
- Testing
- Sitagliptin 100mg
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Beijing Chao Yang Hospital