Clinical trials: sponsored by Benha University
Scar Niche, Myometrial Remodeling
Postplacental Copper Intrauterine Device Versus Postpartum Progesterone-only Pills on Uterine Niche Formation
The purpose of the study is to determine whether immediate postplacental copper T380A intrauterine device insertion increases uterine-niche incidence compared with postpartum progestin-only pills after primary cesarean section .
- Conditions
- Scar Niche, Myometrial Remodeling, Contraceptive Device; Complications, Cesarean Section Complications
- Trial name
- T380A (NCT07264933)
- Testing
- Primary Cesarean Section, immediate postplacental insertion of a copper T380A intrauterine device, progesterone-only pills
- Where
- Egypt
- Volunteers
- 750 people
- Sponsor
- Benha University
Lower Limb Fracture
Prognostic Value of Preoperative Frailty Assessment in Geriatric Lower Limb Orthopedic Surgery
This retrospective study evaluates the effectiveness of frailty assessment tools-specifically the Risk Analysis Index (RAI) and the 5-Item Modified Frailty Index (5-mFI)-in predicting postoperative outcomes for elderly patients…
- Trial name
- NCT07422025
- Testing
- Preoperative Frailty Scoring
- Where
- Egypt
- Volunteers
- 149 people
- Sponsor
- Benha University
Abnormal Uterine Bleeding, Cesarean Section Complications
Oral Contraceptive Pills Versus Levonorgestrel-Releasing Intrauterine System for Niche-Related Abnormal Uterine Bleeding
The purpose of the study is to compare the clinical efficacy and niche morphological changes following treatment with combined oral contraceptive pills (OCPs) versus a levonorgestrel-releasing intrauterine system (LNG-IUS) in…
- Conditions
- Abnormal Uterine Bleeding, Cesarean Section Complications, Uterine Scar
- Trial name
- NCT07229209
- Testing
- transvaginal ultrasonography, monophasic combined oral contraceptive pill, 52 mg levonorgestrel-releasing intrauterine system
- Where
- Egypt
- Volunteers
- 166 people
- Sponsor
- Benha University
Hepatocellular Carcinoma
Utility of MicroRNAs for Diagnosing Hepatocellular Carcinoma in Hepatitis C Patients
This study evaluates a target population of patients with Hepatitis C virus (HCV) infection, including those with complications like liver cirrhosis (LC) and hepatocellular carcinoma (HCC), to investigate the diagnostic utility…
- Trial name
- NCT07404566
- Testing
- PCR
- Where
- Egypt
- Volunteers
- 84 people
- Sponsor
- Benha University
VKH Syndrome
Oral Prednisolone Versus Posterior Sub-Tenon Triamcinolone for Acute Ocular VKH
Vogt-Koyanagi-Harada (VKH) disease is a rare autoimmune disorder characterized by bilateral ocular inflammation that may lead to serous retinal detachment and permanent visual impairment if not promptly treated.
- Trial name
- VKH-OC (NCT07405489)
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Benha University
Meconium Aspiration Syndrome
Interleukin-6 in the Development of Meconium Aspiration Syndrome in Newborn
This trial is intended to assess the serum levels of interleukin-6 as a predictive factor for the occurrence of meconium aspiration syndrome in infants born with MSAF.
- Trial name
- NCT07394322
- Testing
- serum interleukin 6
- Where
- Egypt
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Benha University
Perioperative Pain
Ultrasound Guided Pericapsular Nerve Block Versus iv Sedation Analgesia in Reduction of Shoulder Dislocation
When someone experiences a shoulder dislocation, it can be extremely painful. Emergency physicians often choose to use conscious sedation to help reduce the pain.
- Trial name
- NCT06034873
- Testing
- Propofol injection and fentanyl, Bupivacain
- Where
- Egypt
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Benha University
Ulcerative Colitis
Effect of Rutin on Inflammation Pathways in Ulcerative Colitis Patients
This study evaluates the therapeutic role of Rutin (a plant-derived flavonoid) in reducing the severity of Ulcerative Colitis (UC).
- Trial name
- NCT07370220
- Testing
- Rutin 500 MG Oral Tablet, Fecal Calprotectin
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Benha University
Spinal Disk Injury
Triple Therapy Strategy for Managing Persistent Pain After Spinal Microdiscectomy
This interventional study evaluates a "triple therapy" approach-combining percutaneous spinal fixation, facet radiofrequency ablation, and epidural steroid/hyaluronidase injection-for patients with Failed Back Surgery Syndrome…
- Trial name
- NCT07370233
- Testing
- Epidural Injection, thermal Radiofrequency Ablation, Spinal Fixation
- Where
- Egypt
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Benha University
Ultrasound, External Oblique Intercostal Plane Block
Ultrasound-Guided External Oblique Intercostal Plane Block Versus Subcostal Transversus Abdominis Plane Block For Perioperative Analgesia in Laparoscopic Sleeve Gastrectomy
This study aims to compare the analgesic efficacy, duration of analgesia, and overall opioid consumption between the external oblique intercostal plane (EOIP) block and subcostal transversus abdominis plane (TAP) block in…
- Conditions
- Ultrasound, External Oblique Intercostal Plane Block, Subcostal Transversus Abdominis Plane Block, Perioperative Analgesia
- Trial name
- NCT07366138
- Testing
- External oblique intercostal plane block, Subcostal transversus abdominis plane block
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- Benha University
Postoperative Pain
Opioid-Free vs Opioid-Based Anesthesia for Nasal Surgeries
The goal of this clinical trial is to evaluate and compare the efficacy, onset, duration of action, analgesic effect, and side effects of opioid-free anesthesia using dexmedetomidine and lignocaine versus conventional…
- Trial name
- Dex/Lido/Fent (NCT07350668)
- Testing
- dexmedetomidine and lignocaine infusion, Fentanyl infusion
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Benha University
Coronary Artery Disease
Prognostic Nutritional Index for Predicting Outcomes Following Coronary Artery Bypass Grafting (CABG) Surgery
Coronary artery bypass grafting (CABG) is a major cardiac surgery associated with risks of serious perioperative complications and mortality.
- Trial name
- NCT07356219
- Testing
- Prognostic Nutritional Index (PNI), Neutrophil-to-Lymphocyte Ratio (NLR), Body Mass Index (BMI)
- Where
- Egypt
- Volunteers
- 117 people
- Sponsor
- Benha University
Ulcerative Colitis
Composite Ratios Boost CRP's Power in Monitoring Ulcerative Colitis.
Inflammatory Bowel Disease (IBD) is a chronic, recurrent condition marked by disturbed levels of various hematological inflammatory cells and a deregulated immune environment.
- Trial name
- NCT07261579
- Testing
- C-Reactive Protein measuring CRP, CRP to Albumin Ratio
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Benha University
Virtual Reality, Dexmedetomidine
Virtual Reality Versus Intravenous Dexmedetomidine on Maternal Anxiety, Stress, Hemodynamics, and Neonatal Outcomes During Cesarean Section
This study aims to compare the efficacy of intravenous dexmedetomidine infusion versus virtual reality (VR) in reducing maternal anxiety, stress, and hemodynamic instability during cesarean section and their effects on neonatal…
- Conditions
- Virtual Reality, Dexmedetomidine, Maternal Anxiety, Stress
- Trial name
- NCT07343843
- Testing
- Dexmedetomidine, Virtual reality
- Where
- Egypt
- Volunteers
- 52 people
- Sponsor
- Benha University
Toxoplasmosis
Role of Circulating MicroRNAs in Differentiating Psychological Disorders Among Women With Chronic Toxoplasmosis
Chronic Toxoplasma gondii (T. gondii) infection is a widespread condition that can negatively affect brain function and is considered a risk factor for various psychiatric conditions, including depression and schizophrenia.
- Trial name
- NCT07346833
- Testing
- Circulating miRNA Expression and T. gondii Serology
- Where
- Egypt
- Volunteers
- 55 people
- Sponsor
- Benha University
Wearable Devices
Wearable Devices for Early Detection of Postoperative Infection
This systematic review aims to evaluate the efficacy, accuracy, and clinical applicability of wearable infection detection wristbands in postoperative patients across ophthalmology, orthopaedic surgery, and general surgery.
- Trial name
- Wearable Wrist (NCT07334925)
- Testing
- White Blood Cell (WBC), C-reactive Protein (CRP)
- Where
- Egypt
- Volunteers
- 1,284 people
- Sponsor
- Benha University
Tear Film Alteration
Effect of Dexmedetomidine on Tear Production in Angioplasty Patients
During medical procedures performed under local anesthesia with sedation, such as angioplasty, the eyes may become dry because normal blinking and tear production can be reduced.
- Trial name
- NCT07326332
- Testing
- Dexmedetomidine, Sedation with Midazolam, Fentanyl, and Propofol
- Where
- Egypt
- Volunteers
- 52 people
- Sponsor
- Benha University
Depression, Anxiety
Impact of Ketamine On Depressive Symptoms In Patients Undergoing Lumbo-peritoneal Shunt Insertion
Postoperative depression is a perioperative psychological complication that severely affects patient recovery and quality of life. In extreme cases, it may lead to suicidal behavior.
- Trial name
- NCT06060210
- Testing
- normal Saline, Ketamine
- Where
- Egypt
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Benha University
ICS
Melatonin Therapy for Improving ICSI Outcomes in Women With Diminished Ovarian Reserve
Diminished ovarian reserve (DOR) is a major challenge in female fertility, often leading to poor oocyte quality and low pregnancy rates during assisted reproduction.
- Trial name
- NCT07318974
- Testing
- Melatonin capsule
- Where
- Egypt
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Benha University
Twin Pregnancy With Antenatal Problem
Cerclage and Progesterone for Twin Pregnancies
Twin pregnancies face a high risk of complications, most notably preterm birth (delivery before 37 weeks), which is a major cause of infant death and illness globally.
- Trial name
- NCT07319715
- Testing
- McDonald Cervical Cerclage, Vaginal Progesterone Therapy (VPT)
- Where
- Egypt
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- Benha University