Clinical trials: open to volunteers, sponsored by Biruni University
Gingivitis and Periodontal Diseases
Alpha-Lipoic Acid as an Adjunct to Non-Surgical Periodontal Treatment in Gingivitis
Gingivitis is an early and reversible form of periodontal disease characterized by an increased inflammatory response to dental biofilm.
- Trial name
- NCT07882394
- Testing
- Alpha-Lipoic Acid 200 mg, Alpha-Lipoic Acid 600 mg
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Biruni University
Schizophenia Disorder, Severe Mental Illness
Effect of Occupational Therapy on Psychosocial Parameters and Functioning in Individuals With Severe Mental Illness
Severe mental illness (SMI), including schizophrenia spectrum disorders and bipolar disorder, is associated with significant impairments in psychosocial functioning, daily life participation, self-efficacy, and social…
- Conditions
- Schizophenia Disorder, Severe Mental Illness, Bipolar Disorder, Nonorganic Psychosis
- Trial name
- OT-SMI (NCT07879118)
- Testing
- Occupational Therapy Group Intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Biruni University
Penile Girth Enhancement
HYAcorp MLF1 Hyaluronic Acid Filler for Penile Girth Enhancement
The goal of this clinical trial is to learn how well HYAcorp MLF1, a hyaluronic acid filler, works for penile girth enhancement in men aged 25 years or older.
- Trial name
- NCT07877077
- Testing
- cross-linked hyaluronic acid
- Where
- Turkey (Türkiye)
- Volunteers
- 65 people
- Sponsor
- Biruni University
Peri-implantitis
Investigation of Macrophage Polarization in Peri-implant Health and Peri-implantitis
Peri-implantitis is a chronic inflammatory disease characterized by plaque-associated inflammation of the peri-implant mucosa and progressive loss of supporting bone around dental implants, which may ultimately lead to implant…
- Trial name
- NCT07569432
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Biruni University
Acne Vulgaris
The Impact of Baseline Hormonal Profiles (DHEAS, FSH, LH) on Treatment Response to Systemic Isotretinoin in Adult Female Patients With Acne Vulgaris
Acne vulgaris is a common dermatological condition in adult women, often influenced by hormonal factors. Androgens such as dehydroepiandrosterone sulfate (DHEAS) can stimulate sebaceous gland activity, while gonadotropins (FSH…
- Trial name
- NCT07818525
- Where
- Turkey (Türkiye)
- Volunteers
- 64 people
- Sponsor
- Biruni University
Facial Paralysis
Video-Based Facial Movement Analysis in Facial Paralysis
This study aims to evaluate facial movements in patients with facial paralysis using video-based objective analysis and to examine the relationship between these video-based measurements and standard clinical assessment scales.
- Trial name
- NCT07780370
- Testing
- Video-Based Objective Facial Motion Analysis
- Where
- Turkey (Türkiye)
- Volunteers
- 49 people
- Sponsor
- Biruni University
Anterior Cruciate Ligament Injury
Psychological Readiness and Return to Sport After ACL Reconstruction
The goal of this observational study is to evaluate psychological readiness, kinesiophobia, subjective knee function, sport activity level, and return-to-sport status in athletes who have undergone primary anterior cruciate…
- Trial name
- NCT07733895
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people
- Sponsor
- Biruni University
Non-Specific Low Back Pain
Spinal Mobilization and Manipulation for Nonspecific Low Back Pain
Low back pain is one of the most common musculoskeletal disorders worldwide and is a major cause of pain and disability. Manual therapy techniques such as spinal mobilization and spinal manipulation are frequently used together…
- Trial name
- SMM-LBP (NCT07749898)
- Testing
- Spinal Mobilization and Manipulation, Conventional Physiotherapy
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Biruni University
Rectal Cancer, Fecal Incontinence and Constipation
Aerobic Exercise and Guided Imagery in Low Anterior Resection Syndrome
Low Anterior Resection Syndrome (LARS) is a common complication after sphincter-preserving rectal cancer surgery and may negatively affect bowel function and quality of life.
- Conditions
- Rectal Cancer, Fecal Incontinence and Constipation, Aerobic Exercise, Guided Imagery Exercise
- Trial name
- NCT07732894
- Testing
- Exercise, guided imagery
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Biruni University
Periodontal Disease
Effects of Adjunctive Synbiotic Supplementation to Non-Surgical Periodontal Therapy in Smokers With Periodontitis
The aim of this study is to evaluate the effects of adjunctive synbiotic supplementation combined with non-surgical periodontal therapy in smokers with periodontitis.
- Trial name
- NCT07672379
- Testing
- Synbiotic supplementation
- Where
- Turkey (Türkiye)
- Volunteers
- 92 people
- Sponsor
- Biruni University
Obesity (BMI>30)
Machine Learning Prediction of Respiratory Muscle Changes and Ventilatory Responses After Incretin-Based Therapy in Obesity
This study aims to evaluate changes in respiratory function, respiratory muscle performance, and ventilatory responses following incretin-based therapy in individuals with obesity, and to identify predictors of these changes…
- Trial name
- NCT07663591
- Testing
- Incretin-based therapy
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Biruni University
Polycystic Ovarian Syndrome (PCOS)
Exercise Programs in Women With PCOS
This study aims to investigate the effectiveness of a digital rehabilitation-supported combined exercise program in women with Polycystic Ovary Syndrome (PCOS).
- Trial name
- NCT07509762
- Testing
- Face-to-face exercise, Digital rehabilitation
- Where
- Turkey (Türkiye)
- Volunteers
- 33 people
- Sponsor
- Biruni University
Brachial Plexus Birth Palsy, Brachial Plexus Palsy
Evaluation of Pain, Upper Extremity Function, and Social Appearance Anxiety in Adults With Obstetric Brachial Plexus Palsy Who Underwent Shoulder Tendon Transfer Surgery
This observational study aims to evaluate pain and upper extremity function in adults with obstetric brachial plexus palsy who underwent shoulder tendon transfer surgery using the Modified Hoffer technique during childhood.
- Conditions
- Brachial Plexus Birth Palsy, Brachial Plexus Palsy, Brachial Plexus Palsy Due to Birth Trauma
- Trial name
- NCT07655271
- Testing
- Clinical Assessment Battery
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Biruni University
Brachial Plexus Birth Palsy, Brachial Plexus Palsy
Validity and Reliability of the Turkish Version of the Impact of Brachial Plexus Injury Questionnaire (IMBPIQ)
The aim of this methodological study is to translate the Impact of Brachial Plexus Injury Questionnaire (IMBPIQ) into Turkish, culturally adapt it, and evaluate its validity and reliability for use in adults with brachial plexus…
- Conditions
- Brachial Plexus Birth Palsy, Brachial Plexus Palsy, Brachial Plexus Palsy Due to Birth Trauma, Obstetric Brachial Plexus Injury
- Trial name
- NCT07654504
- Testing
- Questionnaire Assessment Battery
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Biruni University
Fertility Preservation, Gynecologic Cancers
A Modular Cloud Platform For Fertility Preservation
The research was designed as a randomized controlled study to determine the effectiveness of a modular cloud-based training platform in increasing awareness of fertility preservation.
- Trial name
- NCT07642531
- Testing
- Developing a Modular Cloud-Based Platform to guide decision-making in fertility preservation
- Where
- Turkey (Türkiye)
- Volunteers
- 140 people
- Sponsor
- Biruni University
Heart Failure
Blood Flow Restriction Combined With Aerobic or Resistance Exercise in Heart Failure
The aim of this study is to compare the clinical effects of aerobic and resistance exercise modalities combined with blood flow restriction in patients with stable heart failure, and to determine the most effective, feasible, and…
- Trial name
- NCT07627737
- Testing
- Aerobic Exercise Plus Blood Flow Restriction Resistance Training, Resistance Training Plus Blood Flow Restriction Aerobic Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Biruni University
Insufficient Keratinized Gingiva
Reharvested Free Gingival Grafts: 3D Shrinkage and Histological Changes
The purpose of this study is to evaluate the dimensional stability of free gingival grafts (FGG) and to investigate the relationship between graft shrinkage (GS) and the histological and biochemical characteristics of grafts…
- Trial name
- NCT07617987
- Testing
- Free gingival graft, Re-harvested free gingival graft
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Biruni University
Obesity
Body Composition, Functional Capacity, and Respiratory Muscle Endurance in Obesity With Restrictive Ventilatory Pattern
This observational cross-sectional study aims to examine the relationship between body composition, functional capacity, and respiratory muscle endurance in individuals with obesity and a restrictive ventilatory pattern.
- Trial name
- NCT07601555
- Testing
- Pulmonary Function, Body Composition, and Functional Capacity Assessment
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Biruni University
Obesity
Respiratory and Exercise Responses by Body Roundness Index in Obesity
This observational study aims to evaluate respiratory performance and exercise responses according to Body Roundness Index (BRI) in individuals with obesity.
- Trial name
- NCT07595822
- Testing
- Observational
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Biruni University
Type 1 Diabetes Mellitus
Examining Multilevel Factors Affecting Participation in Physical Activity Among Adolescents With Type 1 Diabetes Using the Socio-Ecological Model
The goal of this observational study is to examine the multilevel factors influencing physical activity participation in adolescents with Type 1 diabetes (T1D) within the framework of the Socio-Ecological Model (SEM).
- Trial name
- NCT07568028
- Where
- Turkey (Türkiye)
- Volunteers
- 55 people
- Sponsor
- Biruni University