Clinical trials: sponsored by Biruni University
Symptomatic Irreversible Pulpitis (SIP), Post Operative Pain After Root Canal Therapy
Effects of Irrigation Activation and Obturation Techniques on Pain After Root Canal Treatment
This randomized controlled clinical trial aimed to compare postoperative pain and analgesic use following single-visit root canal treatment performed using different final irrigation activation and root canal obturation…
- Trial name
- NCT07882368
- Testing
- Conventional Needle Irrigation, Sonic Irrigation Activation, Cold Lateral Condensation
- Where
- Turkey (Türkiye)
- Volunteers
- 72 people
- Sponsor
- Biruni University
Gingivitis and Periodontal Diseases
Alpha-Lipoic Acid as an Adjunct to Non-Surgical Periodontal Treatment in Gingivitis
Gingivitis is an early and reversible form of periodontal disease characterized by an increased inflammatory response to dental biofilm.
- Trial name
- NCT07882394
- Testing
- Alpha-Lipoic Acid 200 mg, Alpha-Lipoic Acid 600 mg
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Biruni University
Penile Girth Enhancement
HYAcorp MLF1 Hyaluronic Acid Filler for Penile Girth Enhancement
The goal of this clinical trial is to learn how well HYAcorp MLF1, a hyaluronic acid filler, works for penile girth enhancement in men aged 25 years or older.
- Trial name
- NCT07877077
- Testing
- cross-linked hyaluronic acid
- Where
- Turkey (Türkiye)
- Volunteers
- 65 people
- Sponsor
- Biruni University
Premature Ejaculation
Dorsal Penile Nerve Cryoneurolysis for Lifelong PE
The goal of this clinical trial was to learn whether adding dorsal penile nerve cryoneurolysis to medication and behavioral therapy helps men with lifelong premature ejaculation.
- Trial name
- NCT07879105
- Testing
- Percutaneous Dorsal Penile Nerve Cryoneurolysis, Sertraline (Oral Antidepressant), Tadalafil 5 mg
- Where
- Turkey (Türkiye)
- Volunteers
- 117 people
- Sponsor
- Biruni University
Schizophenia Disorder, Severe Mental Illness
Effect of Occupational Therapy on Psychosocial Parameters and Functioning in Individuals With Severe Mental Illness
Severe mental illness (SMI), including schizophrenia spectrum disorders and bipolar disorder, is associated with significant impairments in psychosocial functioning, daily life participation, self-efficacy, and social…
- Conditions
- Schizophenia Disorder, Severe Mental Illness, Bipolar Disorder, Nonorganic Psychosis
- Trial name
- OT-SMI (NCT07879118)
- Testing
- Occupational Therapy Group Intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Biruni University
Interstitial Lung Disease With Systemic Sclerosis
Pelvic Floor Dysfunction in Pulmonary Systemic Sclerosis
Systemic sclerosis (SSc) is a heterogeneous multisystem disease characterized by vascular dysfunction, immune abnormalities, and progressive fibrosis of the skin and internal organs.
- Trial name
- NCT07817160
- Testing
- Pelvic Floor Health Knowledge Assessment, Pelvic Floor Dysfunction Assessment, Core Endurance Assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 37 people
- Sponsor
- Biruni University
Neuromuscular Electrical Stimulation
Effects of Lower Extremity Functional Exercise Program and Neuromuscular Electrical Nerve Stimulation in Older Adults
The aim of this study was to investigate and compare the effects of lower extremity functional exercise program and neuromuscular electrical nerve stimulation on muscle thickness, muscle strength, gait and fall risk in the…
- Trial name
- NCT07076797
- Testing
- EXERCISE TRAINING, NMES
- Where
- Turkey (Türkiye)
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Biruni University
Peri-implantitis
Investigation of Macrophage Polarization in Peri-implant Health and Peri-implantitis
Peri-implantitis is a chronic inflammatory disease characterized by plaque-associated inflammation of the peri-implant mucosa and progressive loss of supporting bone around dental implants, which may ultimately lead to implant…
- Trial name
- NCT07569432
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Biruni University
Acne Vulgaris
The Impact of Baseline Hormonal Profiles (DHEAS, FSH, LH) on Treatment Response to Systemic Isotretinoin in Adult Female Patients With Acne Vulgaris
Acne vulgaris is a common dermatological condition in adult women, often influenced by hormonal factors. Androgens such as dehydroepiandrosterone sulfate (DHEAS) can stimulate sebaceous gland activity, while gonadotropins (FSH…
- Trial name
- NCT07818525
- Where
- Turkey (Türkiye)
- Volunteers
- 64 people
- Sponsor
- Biruni University
Autism Spectrum Disorder
OCCUPATIONAL THERAPY INTERVENTIONS ON COGNITIVE PERFORMANCE IN CHILDREN WITH AUTISM SPECTRUM DISORDER
Autism Spectrum Disorder (ASD) is a neurodevelopmental disorder characterized by deficits in social communication and interaction, as well as restricted and repetitive patterns of behavior.
- Trial name
- COGNITIVE PERF (NCT07818538)
- Testing
- Virtual Reality-Supported Cognitive-Focused Occupational Therapy, Structured Occupational Therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 32 people
- Sponsor
- Biruni University
Menstrual Cycle, Athletes
Menstruel Cycle Knowledge Questionnaite
Menstrual health is an important component of women's physical, mental, and social well-being. Adequate knowledge of the menstrual cycle is essential for distinguishing between normal and abnormal menstrual patterns, facilitating…
- Trial name
- NCT07766577
- Testing
- Menstrual Cycle Knowledge Questionanire, Menstrual Symptom Scale, Health Literacy in Sports
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 121 people, healthy volunteers welcome
- Sponsor
- Biruni University
Facial Paralysis
Video-Based Facial Movement Analysis in Facial Paralysis
This study aims to evaluate facial movements in patients with facial paralysis using video-based objective analysis and to examine the relationship between these video-based measurements and standard clinical assessment scales.
- Trial name
- NCT07780370
- Testing
- Video-Based Objective Facial Motion Analysis
- Where
- Turkey (Türkiye)
- Volunteers
- 49 people
- Sponsor
- Biruni University
Anterior Cruciate Ligament Injury
Psychological Readiness and Return to Sport After ACL Reconstruction
The goal of this observational study is to evaluate psychological readiness, kinesiophobia, subjective knee function, sport activity level, and return-to-sport status in athletes who have undergone primary anterior cruciate…
- Trial name
- NCT07733895
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people
- Sponsor
- Biruni University
Headache, Migraine, Manuel Therapy
The Effect of Two Different Massages on Migraine
The study aims to compare the effects of connective tissue massage on pain severity, attack frequency and duration, migraine-related disability, and quality of life in patients diagnosed with migraine, by comparing them with the…
- Trial name
- NCT05452330
- Testing
- Connective tissue massage, Classical massage
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Biruni University
Healthy Participants, Inactivity
Exercise Approaches and Physical Activity Level in Inactive Adults
This randomized, controlled, single-blind study aims to compare the effects of different exercise approaches on physical activity level and health-related outcomes in inactive adults.
- Conditions
- Healthy Participants, Inactivity, Exercise Training
- Trial name
- NCT07411248
- Testing
- Face-to-Face Supervised Exercise, Mobile App-Based Exercise, Home-Based Video Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Biruni University
Healthy, Chronic Ankle Instability, CAI
Relationship Between Muscle Strength and Balance
This study aims to examine the relationship between lower extremity muscle strength and balance and to compare these parameters between healthy individuals and individuals with lower extremity injuries.
- Conditions
- Healthy, Chronic Ankle Instability, CAI, Anterior Cruciate Ligament Injury, Muscle Strengh
- Trial name
- NCT07419750
- Where
- Turkey (Türkiye)
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Biruni University
Non-Specific Low Back Pain
Spinal Mobilization and Manipulation for Nonspecific Low Back Pain
Low back pain is one of the most common musculoskeletal disorders worldwide and is a major cause of pain and disability. Manual therapy techniques such as spinal mobilization and spinal manipulation are frequently used together…
- Trial name
- SMM-LBP (NCT07749898)
- Testing
- Spinal Mobilization and Manipulation, Conventional Physiotherapy
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Biruni University
Rectal Cancer, Fecal Incontinence and Constipation
Aerobic Exercise and Guided Imagery in Low Anterior Resection Syndrome
Low Anterior Resection Syndrome (LARS) is a common complication after sphincter-preserving rectal cancer surgery and may negatively affect bowel function and quality of life.
- Conditions
- Rectal Cancer, Fecal Incontinence and Constipation, Aerobic Exercise, Guided Imagery Exercise
- Trial name
- NCT07732894
- Testing
- Exercise, guided imagery
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Biruni University
Keloid, Tattoo
Tattooing and Piercing Among Medical Students
The aim of this study is to evaluate medical students' attitudes towards tattoos and piercings and to measure their awareness of associated dermatological risks.
- Conditions
- Keloid, Tattoo, Infection, Scar
- Trial name
- NCT07673484
- Where
- Turkey (Türkiye)
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Biruni University
Low Back Pain
Hamstring Stretching Effective on Nonspecific Low Back Pain
Low back pain is one of the most common complaints in the world and can be considered a universal health problem for humanity. Low back pain is a multifactorial disease with multiple etiologies.
- Trial name
- Hams (NCT06837753)
- Testing
- Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 46 people
- Sponsor
- Biruni University