Clinical trials: sponsored by Boston Medical Center
Cutaneous Abscess
A Comparison of Techniques for Treating Skin Abscesses
Management of abscesses traditionally involves incision and drainage (I\&D). Abscesses are frequently are "packed" or stented open with the presence of a wick, and traditional care requires re-visits every 2-3 days to have the…
- Trial name
- LoopDrainage (NCT01897675)
- Testing
- Incision and Drainage with packing (wick) placement, Abscess drainage with loop placement
- Where
- United States
- Volunteers
- 233 people
- Sponsor
- Boston Medical Center
Depression
Reducing Hospital Readmissions in Patients With Depressive Symptoms
Project Re-Engineered Discharge (Project RED) has previously demonstrated that patients who received the RED were 30% less likely than patients receiving usual care to access inpatient or emergency services within 30 days of…
- Trial name
- RED-D (NCT01840826)
- Testing
- RED-D Care Management
- Where
- United States
- Volunteers
- 709 people
- Sponsor
- Boston Medical Center
Chronic Pain
Our Whole Lives: Online Chronic Pain Management
This project will work to increase knowledge about the utility of a website for management of chronic pain, Our Whole Lives (OWL). It will do so by examining barriers and facilitators to patient use.
- Trial name
- OWL (NCT02788539)
- Testing
- Our Whole Lives Website
- Where
- United States
- Volunteers
- 43 people
- Sponsor
- Boston Medical Center
Alcohol-Related Disorders, Anxiety Disorders
Psychosocial and Medication Treatment for Anxiety in Alcoholism
The proposed project is written as a "typical clinical practice" test and is a fully-controlled trial of a combined anxiety-focused CBT and pharmacotherapy (venlafaxine; CBT-VEN) delivered for patients with comorbid alcohol-use…
- Trial name
- NCT00248612
- Testing
- Venlafaxine, CBT, Progressive muscle relaxation therapy (PMR)
- Where
- 2 sites in United States
- Volunteers
- 162 people
- Sponsor
- Boston Medical Center
Head and Neck Cancer
Stereotactic Radiosurgery in Treating Patients With Locally Advanced or Recurrent Head and Neck Cancer
RATIONALE: Stereotactic radiosurgery may be able to send x-rays directly to the tumor and cause less damage to normal tissue. PURPOSE: This phase I trial is studying the side effects of stereotactic radiosurgery in treating…
- Trial name
- NCT00851253
- Testing
- stereotactic radiosurgery
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Boston Medical Center
Respiratory Insufficiency
Clinical Trial of a Computer-driven Weaning System for Patients Requiring Mechanical Ventilation
The purpose of this study is to compare the efficacy of a computer-assisted ventilator weaning system (Drager Smartcare) to our current standard of care in the medical intensive care unit.
- Trial name
- NCT00606554
- Testing
- Computer-assisted weaning program, Standard of Care weaning
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- Boston Medical Center
Surgical Wound
Outcomes Comparing Different Methods of Skin Closure in Patients Undergoing Head and Neck Surgery.
When patients undergo neck dissection surgeries, the current standard of care is to close the skin layer with either metal staples, which are removed a few days post-operatively, or with sutures, which can be absorbable or…
- Trial name
- NCT02936063
- Testing
- Surgical staples, Subcuticular sutures
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Boston Medical Center
Smoking Cessation
Patient Navigation and Financial Incentives to Promote Smoking Cessation
Cigarette smoking is a significant health threat. To eliminate disparities in cancer burden, smoking rates must be reduced among populations where smoking is disproportionately concentrated: those with low socioeconomic status…
- Trial name
- NCT02351609
- Testing
- Intervention, Enhanced Traditional Care control
- Where
- United States
- Volunteers
- 352 people, healthy volunteers welcome
- Sponsor
- Boston Medical Center
Social Isolation
Mobilizing Community Networks to Optimize Child Well-being
Caregiver social isolation adversely impacts child health and developmental outcomes; it also contributes to suboptimal engagement in health care services and enrichment resources, which also elevate risk for poor outcomes in…
- Trial name
- NOW (NCT02622399)
- Testing
- Project NOW
- Where
- United States
- Volunteers
- 98 people, healthy volunteers welcome
- Sponsor
- Boston Medical Center
Obesity
Reducing Obesity in Underserved Postpartum African American Women
In this proposal, the investigators will develop a culturally-tailored, 8-week clinic-based weight loss program to reduce obesity among postpartum African American (AA) adult women that can be integrated into a postpartum care…
- Trial name
- RENEW (NCT02448563)
- Testing
- Nutrition and physical activity education
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- Boston Medical Center
Fecal Immunochemical Test
Efficacy of Fecal Immunochemical Test Using Digital Rectal Exam
This study will investigate the use of digital rectal exam (DRE) to obtain stool samples for the fecal immunochemical test (FIT) in patients due for screening colonoscopy and in pre-operative patients with known colorectal…
- Trial name
- FIT-DRE (NCT03013855)
- Testing
- FIT-SOC, FIT-DRE
- Where
- United States
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- Boston Medical Center
Cardiovascular Diseases, Heart Diseases
Educational and Supportive Interventions to Prevent Cardiopulmonary Rehospitalization
This study will use a comprehensive hospital discharge toolkit to implement up-to-date guidelines for cardiopulmonary diseases. The study will also include a computer-based patient-education program and a telephone-based…
- Trial name
- NCT00217867
- Testing
- Animated character intervention with telephone follow-up
- Where
- United States
- Volunteers
- 832 people
- Sponsor
- Boston Medical Center
Preconception Care
Study of Virtual Patient Advocate for Preconception Care for African American Women
This study is to examine the effectiveness of a health communication system (Gabby) that assesses preconception health risks and tailors the intervention to each subject, based on her health risks.
- Trial name
- "Gabby" (NCT01812824)
- Testing
- Intervention (Virtual Patient Advocate)
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Boston Medical Center
HIV Infections
Project HERMITAGE: HIV Prevention in Hospitalized Russian Drinkers
The objective of this study is to test in a randomized controlled trial the effectiveness of a US secondary HIV prevention program to reduce HIV risk behaviors, STD acquisition, and alcohol consumption among HIV-infected Russians…
- Trial name
- NCT00483483
- Testing
- Individual and group HIV risk behavior counseling sessions, health education and support group
- Where
- 3 sites in Russia
- Volunteers
- 700 people
- Sponsor
- Boston Medical Center
Alcohol Dependence, Drug Dependence
Russia PREVENT (HIV Prevention Partnership in Russian Alcohol Treatment)
The purpose of this study is to test an HIV prevention intervention in a Russian substance abuse treatment facility using a randomized trial study design.
- Trial name
- NCT00183118
- Testing
- Adapted Enhanced-RESPECT (HIV prevention intervention)
- Where
- United States
- Volunteers
- 180 people
- Sponsor
- Boston Medical Center
Metastatic Cancer
Stereotactic Radiosurgery in Treating Patients With Spinal Metastases
RATIONALE: Stereotactic radiosurgery can send x-rays directly to the tumor and cause less damage to normal tissue. It may also help patients with spinal metastases live more comfortably.
- Trial name
- NCT00853528
- Testing
- questionnaire administration, diffusion tensor imaging, functional magnetic resonance imaging
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- Boston Medical Center
Acute Respiratory Failure
Variable Ventilation During Acute Respiratory Failure
Acute respiratory failure requiring support with mechanical ventilation occurs with an incidence of 77-100 per 100,000 person-years and accounts for half of all patients admitted to the intensive care unit.
- Trial name
- NCT01083277
- Testing
- variable ventilation, Conventional ventilation
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- Boston Medical Center
Delirium
Reducing Delirium in the Surgical Intensive Care Unit
Delirium is an acute disturbance in mental abilities and confusion that affects many patient in the hospital and is caused by multiple factors including and altered sleep/wake cycles and multiple sedating medications.
- Trial name
- NCT02856737
- Testing
- eye masks and earplugs
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Boston Medical Center
PrEP for Conception Purposes
PrEPception: Expanding Assisted Reproductive Options for Serodiscordant Couples
The purpose of this study is to observe patient response to current clinical practice utilizing TRUVADA (emtricitabine and tenofovir disoproxil fumarate) for Pre-Exposure Prophylaxis (PrEP) amongst HIV serodiscordant couples…
- Trial name
- NCT02233192
- Where
- 4 sites in United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Boston Medical Center
Paradoxical Vocal Fold Motion Disorder, Vocal Cord Dysfunction
Treatment of Paradoxical Vocal Fold Motion Disorder (PVFMD) With a Form of Respiratory Retraining Technique
Paradoxical Vocal Fold Motion Disorder (PVFMD), otherwise known as vocal cord dysfunction (VCD) is a laryngeal breathing disorder that has several potential causes. In some individuals, exertion is the predominant trigger.
- Trial name
- PVFMDRespRet (NCT02859974)
- Testing
- Respiratory retraining for PVFMD
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Boston Medical Center