Clinical trials: sponsored by Boston University
HIV
HIV Testing in Community Health Center Dental Clinics
This is a cluster randomized trial among dental clinics (n=4) to evaluate whether rapid HIV testing (RHT) during dental visits improves HIV testing rates compared to referral for laboratory HIV testing.
- Trial name
- TEETH (NCT07089849)
- Testing
- Rapid HIV testing, Referral for HIV testing
- Where
- 4 sites in United States
- Volunteers
- 6,715 people, healthy volunteers welcome
- Sponsor
- Boston University
Physical Activity
Measuring Outcomes With Validated Exercise
Physical activity and its intensity level is a critical determinant of health. Digital Health Technologies, such as wearable accelerometers (wrist-worn watch-like devices), can provide researchers and clinicians with objective…
- Trial name
- MOVE (NCT07270185)
- Where
- United States
- Volunteers
- 42 people
- Sponsor
- Boston University
HIV
Integrating U=U Into HIV Counseling in South Africa (INTUIT-2.0)
Undetectable = Untransmittable (U=U) is the scientific consensus that people with human immunodeficiency virus (HIV) who achieve viral suppression through antiretroviral treatment (ART) cannot transmit the virus sexually.
- Trial name
- NCT07199634
- Testing
- "Undetectable & You" HIV treatment literacy app
- Volunteers
- 880 people
- Sponsor
- Boston University
Hearing Loss
Improving Spatial Perception and Speech Understanding in Multitalker Mixtures
The purpose of this study is to investigate several approaches for improving spatial perception and speech intelligibility in multitalker listening situations for hearing-aid users.
- Trial name
- NCT05260307
- Testing
- hearing aid condition
- Where
- United States
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- Boston University Charles River Campus
Alzheimer Disease
Improving Memory in Alzheimer's Disease With Noninvasive Brain Stimulation
The investigators will evaluate the theory that Alzheimer's disease-related memory impairment derives from the inefficient orchestration of rhythmic activity at the level of large-scale cortical networks.
- Trial name
- NCT06094192
- Testing
- High definition transcranial electrical current stimulation
- Where
- United States
- Volunteers
- 204 people, healthy volunteers welcome
- Sponsor
- Boston University Charles River Campus
Mental Disorders, Employment
Mastering the World of Work (MWW): RCT
The purpose of this study is to conduct a randomized clinical trial for an innovative intervention entitled "Mastering the World of Work" (MWW).
- Conditions
- Mental Disorders, Employment, Metacognition, Employment, Supported
- Trial name
- NCT05206188
- Testing
- Mastering the World of Work (MWW)
- Where
- United States
- Volunteers
- 46 people
- Sponsor
- Boston University Charles River Campus
Osteo Arthritis Knee
The Role of Vitamin K on Knee Osteoarthritis Outcomes
The appropriate form and dosing of vitamin K to benefit relevant outcomes in knee osteoarthritis (OA) are not known. In intervention studies for conditions other than knee OA (e.g., prevention of cardiovascular disease), the most…
- Trial name
- NCT06385275
- Testing
- Vitamin K1 500 µg, K1 1000 µg, Vitamin K2 (MK-7) 300 µg
- Where
- United States
- Volunteers
- 49 people
- Sponsor
- Boston University
Knee Osteoarthritis
Telehealth Exercise and Mindfulness for Pain in Osteoarthritis - Stage 1B
The goal of this randomized controlled trial (RCT) is to test the feasibility of an 10-week telehealth mindful exercise intervention compared to a telehealth exercise only intervention for people with knee osteoarthritis (OA).
- Trial name
- TEMPO-1B (NCT06684587)
- Testing
- Exercise Program, Mindful Exercise
- Where
- United States
- Volunteers
- 66 people
- Sponsor
- Boston University Charles River Campus
Deafness
Word Learning in Deaf Children Using Eye-tracking and Behavioral Measures
Mutual exclusivity is a word learning constraint in which the learner assumes that a given word refers to only one category of objects.
- Trial name
- NCT05993832
- Testing
- input cue
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- Boston University Charles River Campus
Gulf War Illness
D-cycloserine: A Novel Treatment for Gulf War Illness (GWDCS)
The purpose of this study is to investigate the efficacy of d-cycloserine (DCS) treatment for Gulf War Illness (GWI). Gulf War veterans with Gulf War Illness experience numerous chronic health symptoms, including cognition and…
- Trial name
- GWDCS (NCT02983734)
- Testing
- D-cycloserine
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- Boston University Charles River Campus
Chronic Pain, Unhealthy Alcohol Use
Integrated Digital Health Approach to Reduce Hazardous Alcohol Use and Chronic Pain Among Rural Populations
The current proposal seeks to test the benefit of a brief intervention combined with a digital program delivered though a smartphone app for reducing chronic pain and hazardous drinking among those in rural settings.
- Trial name
- NCT07804914
- Testing
- Mobile Intervention for Alcohol and Pain, Control Intervention
- Where
- United States
- Volunteers
- 260 people
- Sponsor
- Boston University Charles River Campus
Anxiety Disorders, Cardiovascular Diseases
Initial Assessment of the Feasibility and Efficacy of a Scalable Digital CBT for Generalized Anxiety and Associated Health Behaviors in a Cardiovascular Disease Population
The treatment of generalized anxiety disorder (GAD) in an accessible manner represents an unmet need for those with cardiovascular disease (CVD), given that patients with CVD experience numerous barriers for in-person treatment…
- Conditions
- Anxiety Disorders, Cardiovascular Diseases, Anxiety, Health Behavior
- Trial name
- NCT04895995
- Testing
- Daylight dCBT Application
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Boston University Charles River Campus
Adolescent Behavior Problem, Mental Health Wellness 1
Future Leaders Program: Testing a Youth Leadership, Engagement, and Mindfulness Program
The current study tests the feasibility and effectiveness of a youth intervention designed to provide meaningful leadership opportunities through the acquisition of leadership skills as well as mindfulness practice, LEAP…
- Trial name
- FLP (NCT06736522)
- Testing
- Leadership, Engagement, and youth Action Program with Mindfulness, EnvisionIT
- Where
- 3 sites in United States
- Volunteers
- 504 people, healthy volunteers welcome
- Sponsor
- Boston University Charles River Campus
Alcohol Use Disorder, Drug Use
A Hybrid Effectiveness Implementation Study of Latino/a Alcohol and Drug Users
Alcohol use is a significant problem among Latinxs and immigration-related stress increases risk for substance use. A theoretically-based cultural adaptation of motivational interviewing (CAMI) that specifically integrated…
- Conditions
- Alcohol Use Disorder, Drug Use, Psychological Distress
- Trial name
- CAMI-HI (NCT04771650)
- Testing
- CAMI
- Where
- 2 sites in United States
- Volunteers
- 91 people, healthy volunteers welcome
- Sponsor
- Boston University Charles River Campus
Breastfeeding, SUID
Social Media and Risk Reduction Teaching-Enhanced Reach
This study aims to improve adherence to American Academy of Pediatrics safe sleep (SS) recommendations and improve rates of initiation and duration of partial and exclusive breastfeeding (BF) through direct education of mothers…
- Conditions
- Breastfeeding, SUID, SIDS
- Trial name
- SMARTER (NCT04387552)
- Testing
- Prenatal Safe Sleep Mobile Health (mHealth) Messaging, Prenatal Breastfeeding Mobile Health (mHealth) Messaging, Postnatal Safe Sleep Mobile Health (mHealth) Messaging
- Where
- United States
- Volunteers
- 2,093 people
- Sponsor
- Boston University
Parkinson's Disease (PD)
A Novel Digital Music-based Autonomous Personalized Walking Intervention to Improve Gait and Walking Automaticity in Parkinson Disease
The purpose of this research study is to examine the effects of a 3-month personalized community-based walking program using a digital music-based device designed for self-directed gait training in people with Parkinson disease…
- Trial name
- MyMusiQ (NCT07705373)
- Testing
- MR-005 (MedRhythms, Inc., Portland, ME)
- Where
- 3 sites in United States
- Volunteers
- 200 people
- Sponsor
- Boston University Charles River Campus
Anxiety Disorder of Childhood
Brief, Remote Treatment of Youth Injection Phobia and Measurement of Novel, Disorder-congruent Cognitive Bias Tasks
This study is investigating the acceptability, feasibility, and preliminary efficacy of a brief, remote treatment for youth injection phobia.
- Trial name
- NCT04972006
- Testing
- Remote, intensive intervention for injection phobia
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- Boston University Charles River Campus
Glucose Response
Glycemic Effects of Meals - Repeatability Trial With Continuous Glucose Monitoring
Almost half of adults in the United States have either diabetes mellitus (DM) or prediabetes (preDM), but many are undiagnosed and unaware of their condition.
- Trial name
- GEM-RT CGM (NCT07293143)
- Testing
- Six meal challenges
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Boston University
Sleep Problem, Behavior, Child
Parents Advancing Toddler Health
Although early interventions can improve health equity in young children living in poverty, this promise often is not realized because of barriers to family engagement.
- Trial name
- PATH (NCT04824989)
- Testing
- Sleep Health in Preschoolers (SHIP), Family Check-Up (FCU), Oral Health, Child Safety, and Environmental Health Intervention (Active Control)
- Where
- 2 sites in United States
- Volunteers
- 305 people, healthy volunteers welcome
- Sponsor
- Boston University Charles River Campus
Alzheimer Disease (AD), Mild Cognitive Impairment (MCI)
Use of a Mobile Brain-Body Imaging Approach to Evaluate the Effects of Rhythmic Auditory Stimulation on Gait and Brain Function in Alzheimer's Disease
Alzheimer's Disease (AD) is associated with impairments in both gait and cognition, significantly increasing fall risk. Falls are a leading cause of injury-related disability in older adults, and individuals with AD experience a…
- Trial name
- NCT07659964
- Testing
- Metronome
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Boston University Charles River Campus