Clinical trials: sponsored by CHU de Reims
Intracranial Aneurysm
Risk Factors for Intracranial Aneurysm Recanalization After Endovascular Treatment.
Endovascular treatment is now the first line treatment for the management of intracranial aneurysms. However aneurysm recanalization is an important limitation to this treatment.
- Trial name
- ARETA (NCT01942512)
- Testing
- Endovascular treatment of intracranial aneurysm
- Where
- 22 sites in France
- Volunteers
- 1,275 people
- Sponsor
- CHU de Reims
Septic Tibial Non-union
Management of Septic Non-union of the Tibia Using the "Induced Membrane" Technique
The aim of the study was to assess clinical and radiological results with the "induces membrane" technique, described by A. C. Masquelet in 1986, in a series of patients with septic non-union of the tibia
- Trial name
- SEPT-LEG (NCT03940638)
- Testing
- Data collection
- Where
- France
- Volunteers
- 18 people
- Sponsor
- CHU de Reims
Surgical Retinal
CD160 Expression in Retinal Vessels is Associated With Retinal Neovascular Diseases
The aims of this study were to analyze CD160 expression in both normal and pathological eyes from human adults to evaluate association between CD160 presence on endothelial cells from blood vessels and retinal vascular disease
- Trial name
- NEOVASC-CD160 (NCT03940664)
- Testing
- immunohistochemistry on Formalin fixed and paraffin embedded blocks
- Where
- France
- Volunteers
- 75 people
- Sponsor
- CHU de Reims
Cervical Cancer
Comparing Health Services Interventions for the Prevention of HPV-related Cancer
The study aims to identify global and local determinants of HPV vaccine acceptability, HPV vaccine uptake and compliance as well as identify logistics and programmatic issues in each country to offer the HPV vaccine, as a…
- Trial name
- CoheaHr-WP4 (NCT02837926)
- Testing
- questionnaire, Gardasil vaccine, Cervarix®
- Where
- France
- Volunteers
- 63 people
- Sponsor
- CHU de Reims
Secondary or Primary Immunodeficiency
Tolerance and Patients' Satisfaction With IGHy
Primary immunodeficiencies (PID) represent more than 150 diseases affecting the immune system. More than 50% of PIDs are due to a lack or an insufficiency in antibody production.
- Trial name
- NCT03668288
- Testing
- Data record and questionnaires passation
- Where
- France
- Volunteers
- 20 people
- Sponsor
- CHU de Reims
Lower Urinary Tract Symptoms, Erectile Dysfunction
Impact of Treatment of Obstructive Sleep Apnea Syndrome by Continuous Positive Airway Pressure Equipment at Night on the Lower Urinary Tract Symptoms and the Erectile Dysfunction
To treat lower urinary tract symptoms (LUTS) and erectile dysfunction (ED), we mainly have symptomatic drug treatments. Some patients are resistant to the treatments that we have or are forced to stop treatments because of side…
- Conditions
- Lower Urinary Tract Symptoms, Erectile Dysfunction, Obstructive Sleep Apneas Syndrom
- Trial name
- NCT03547596
- Testing
- questionnaire passation
- Where
- France
- Volunteers
- 300 people
- Sponsor
- CHU de Reims
Postnatal Depression
Postnatal Depression, Attachment and Self-defining Memories
The specificity of postnatal depression (PND) was acted as full entity within the depressions, by B. Pitt in 1968, through the description of a specific nosography which describes "an atypical depression of the post-partum ".
- Trial name
- PNDattachMEMO (NCT03346551)
- Testing
- Evaluation of the quality attachment : "Adult Attachment Narratives" and "CaMir scale", Evaluation of the self-defining memories : "Specific Questionnaire during an interview"
- Where
- France
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- CHU de Reims
All Surgery
Noise Impact in the Post-anesthesia Care Unit
World health organization recommends noise level should be less than 30db in hospital. However many analysis conclude to an average of 67dB in the post anesthesia care unit.
- Trial name
- Post op NOISE (NCT03537820)
- Testing
- questionnaire
- Where
- France
- Volunteers
- 816 people
- Sponsor
- CHU de Reims
Acute Coronary Syndrome
Markers of Vascular Aging and Coronary Syndrome
Atherosclerosis and aging are associated to the raise of biochemical alterations of proteins grouped under the name of " non-enzymatic post-translational modifications ".
- Trial name
- MAVASCOR (NCT02857387)
- Testing
- blood sample withdrawn
- Where
- France
- Volunteers
- 65 people
- Sponsor
- CHU de Reims
Pituitary Adenomas
Predictive Factors of Recurrence of Non Functioning Pituitary Adenomas : a Retrospective Study of 220 Patients in the Reims University Hospital, France
Non functioning pituitary adenomas (NFPAs) are the most common pituitary adenomas. Their growth is usually slow and diagnosis is often made in the context of masse effect .The therapeutic alternatives are surgery and radiotherapy…
- Trial name
- NCT02803697
- Testing
- Patients
- Where
- France
- Volunteers
- 106 people
- Sponsor
- CHU de Reims
Hidradenitis Suppurativa
Association Between Hidradenitis Suppurativa and Spondyloarthritis
Hidradenitis suppurativa is a chronic dermatosis, characterized by an inflammation of the follicular epithelium in the apocrine glands.
- Trial name
- VESPA (NCT03668925)
- Testing
- magnetic resonance imaging (MRI) of the sacro-iliac region HLA B27 test C-reactive protein (CRP) measurement
- Where
- France
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- CHU de Reims
Reproducibility, Four Part Fracture
Analysis of Four-fragment Fractures of the Proximal Humerus: the Interest of 2D and 3D Imagery and Inter- and Intra-observer Reproducibility
Fractures of the proximal humerus are increasingly frequent, with numbers tripling between the 1970s and the 2000s. Among these fractures, those involving the tuberosities and also the anatomic neck are a therapeutic challenge.
- Conditions
- Reproducibility, Four Part Fracture, Proximal Humerus Fracture, Hertel's Criteria
- Trial name
- REPROD-HUMERUS (NCT03646253)
- Testing
- Analysis of radiology (standard radiographies, 2D scan sections and 3D reconstructions)
- Where
- France
- Volunteers
- 20 people
- Sponsor
- CHU de Reims
Small Intestinal Carcinoid Tumors
Clinic, Pathologic and Genetic Characterization of Patients With Familial Carcinoid Tumors (Study From the GTE, Groupe d'étude Des Tumeurs Endocrines)
Small intestine carcinoid tumors are rare. Small intestine Familial Carcinoid Tumors (FCT) are defined by the occurrence of at least 2 cases of this tumor type in first- or second-degree relatives.
- Trial name
- NCT03622333
- Testing
- Research of constitutional genetic alterations
- Where
- France
- Volunteers
- 60 people
- Sponsor
- CHU de Reims
Dementia
Adverse Drug Reactions in Older Subjects
Objective: To identify risk factors for the occurrence of adverse drug reactions (ADRs) based on geriatric evaluation. Design: Longitudinal prospective study from May 2010 to November 2011.
- Trial name
- RiskofADR (NCT03623542)
- Where
- France
- Volunteers
- 293 people
- Sponsor
- CHU de Reims
Obesity
Evolution of Dyspnea After Bariatric Surgery in Patient With Obesity
Obesity, defined as a Body Mass Index greater than or equal to 30 kg/m2, represents a significant public health issue. Dyspnea is a very common and crippling symptom in obesity.
- Trial name
- OBES-DYSP (NCT03623204)
- Testing
- Dyspnea evaluation
- Where
- France
- Volunteers
- 57 people
- Sponsor
- CHU de Reims
Erosive Pustular Dermatosis of the Leg
Clinical Aspect of Erosive Pustular Dermatosis of the Leg
Erosive pustular dermatosis of the leg is a fairlyrecent clinical entity that was described the first time in 1987. Diagnosis of erosive pustular dermatosis of the leg is made on clinical grounds.
- Trial name
- Clin-EPDL (NCT03623191)
- Testing
- Clinical examination
- Where
- France
- Volunteers
- 45 people
- Sponsor
- CHU de Reims
Papillary Thyroid Cancer
Overdiagnosis of Thyroid Cancer in the Marne and Ardennes Departments of France From 1975 to 2014
Introduction - Incidence of thyroid cancer has increased considerably in France in recent years, but the mortality rate has declined only slightly. Part of this increased incidence could be attributable to overdiagnosis.
- Trial name
- OTCancer (NCT03623516)
- Where
- France
- Volunteers
- 2,008 people
- Sponsor
- CHU de Reims
Odontology
Physiological and Oral Dental Parameters of Young Child
The aim of this study is to measure some oral and maxillofacial physiological parameters, with a view to creating a modular prototype articulator from young children to adolescents by 3D printing.
- Trial name
- PhyDentchild (NCT03620214)
- Where
- France
- Volunteers
- 90 people
- Sponsor
- CHU de Reims
Transformed Waldenström Macroglobulineamia
Transformed Waldenström Macroglobulineamia
Histological transformation to diffuse large B-cell lymphoma is a rare complication which may occur in Waldenstrom macroglobulinemia.
- Trial name
- tWM (NCT03611959)
- Testing
- Non Applicable
- Where
- France
- Volunteers
- 77 people
- Sponsor
- CHU de Reims
Type 1 Diabetes
Continuous Glucose Monitoring and Hypoglycemia Unawareness in Type 1 Diabetes
Looking for strict normoglycemia in type 1 diabetes increases the risk of hypoglycemia, exposing to hypoglycemia unawareness. It has been shown that the early correction of hypoglycemia can help recovering the perception of…
- Trial name
- NCT03605979
- Where
- France
- Volunteers
- 11 people
- Sponsor
- CHU de Reims