Clinical trials: sponsored by Capital Medical University
Influenza, Human, Critical Illness
A Pharmacokinetics Study of Favipiravir in Patients With Severe Influenza
Title: An adaptive study of the pharmacokinetics of favipiravir in patients with severe influenza Study Design: An open label, single group assignment, adaptive study to evaluate the pharmacokinetics of favipiravir in adult…
- Conditions
- Influenza, Human, Critical Illness, Influenza
- Trial name
- NCT03394209
- Testing
- Favipiravir, Oseltamivir 75Mg Capsule
- Where
- China
- Volunteers
- 34 people
- Sponsor
- Capital Medical University
Acute Ischemic Stroke
Biomarkers to Predict Hemorrhage and Outcomes After Endovascular Treatment in Patients With Acute Large Vessel Occlusion
The main aim of the biomarkers to predict Hemorrhagic transformation(HT) after endovascular treatment in Acute Ischemic Stroke Patients. The study has three main parts.
- Trial name
- NCT03915834
- Testing
- Endovascular treatment
- Where
- 2 sites in China
- Volunteers
- 300 people
- Sponsor
- Capital Medical University
Neoplasms
Rivaroxaban Versus Low-molecular-weight Heparin for Preventing Thrombosis in Cancer Patients
The study is designed to compare the efficacy and safety of oral rivaroxaban and subcutaneous low-molecular-weight heparin in preventing femoral venepuncture associated thrombosis among cancer patients.
- Trial name
- NCT03282643
- Testing
- Rivaroxaban 10 MG, Rivaroxaban 20 MG, Low-molecular-weight heparin
- Where
- China
- Volunteers
- 74 people
- Sponsor
- Capital Medical University
Mechanical Ventilation, Electrical Impedance Tomography
Inhomogeneous Ventilation in Adult Post-neurosurgical Patients
Inhomogeneous ventilation was more likely to happen in patients after general anesthesia. Inhomogeneous ventilation may associate with ventilator-induced lung injury.
- Conditions
- Mechanical Ventilation, Electrical Impedance Tomography, Inhomogeneous Ventilation, Neurosurgery
- Trial name
- NCT03830099
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Capital Medical University
GERD
A New System for GERD Diagnosis and Treatment
This is a pilot study measuring a new diagnosis and treatment system "EAISMLP" in adult patients with gastroesophageal reflux disease (GERD).
- Trial name
- EAISMLP (NCT03600974)
- Testing
- Stretta, Laparoscopic Nissen fundoplication, Probiotic Agent
- Volunteers
- 200 people
- Sponsor
- Capital Medical University
Major Depressive Disorder
Effectiveness Study of Scopolamine Combined With Escitalopram in Patients With MDD
Despite the availability of a wide range of antidepressant drugs, clinical trials indicate that 30% to 40% of patients with major depression fail to respond to first-line antidepressant treatment, despite adequate dosage…
- Trial name
- SCE (NCT03131050)
- Testing
- Scopolamine, Escitalopram, Saline
- Where
- China
- Volunteers
- 66 people
- Sponsor
- Capital Medical University
Carotid Artery Stenosis
Safety and Efficacy of Low Dosage of Terazosin in Subjects Undergoing Carotid Artery Stenting
The purpose of this study is to assess the safety and efficacy of low dosage of Terazosin in Carotid Artery Stenting
- Trial name
- TZ-CAS (NCT03195673)
- Testing
- Terazosin, Carotid artery stenting
- Where
- 2 sites in China
- Volunteers
- 160 people
- Sponsor
- Capital Medical University
Mechanical Thrombectomy, Stroke
Efficacy and Safety of Balloon Guide Catheter in Mechanical Thrombectomy Patients
With mechanical thrombectomy now representing standard of care for treatment of acute ischemic stroke secondary to large vessel occlusion, identifying adjunctive techniques that result in improved outcomes for patients with LVO…
- Conditions
- Mechanical Thrombectomy, Stroke, Balloon Guide Catheter
- Trial name
- ESCAPE (NCT03754738)
- Testing
- Balloon guide catheter, Non-balloon guide catheter
- Where
- 6 sites in China
- Volunteers
- 155 people
- Sponsor
- Capital Medical University
Aneurysm, Ruptured, Coiling Therapy
The Neuroprotective Effect of Remote Ischemic Conditioning in Ruptured Aneurysm Coiling Therapy
The overall incidence of DWI positive for thromboembolic events following endovascular treatment of intracranial aneurysms is proximately 50%.
- Trial name
- NEAT-2 (NCT03561311)
- Testing
- remote ischemic conditioning
- Where
- 5 sites in China
- Volunteers
- 210 people
- Sponsor
- Capital Medical University
Aneurysm
The Neuroprotective Effect of Remote Ischemic Conditioning in Aneurysm Coiling Therapy
The overall incidence of DWI positive for thromboembolic events following endovascular treatment of intracranial aneurysms is proximately 50%.
- Trial name
- NEAT (NCT03496415)
- Testing
- remote ischemic conditioning
- Where
- 6 sites in China
- Volunteers
- 210 people
- Sponsor
- Capital Medical University
Acute Ischemic Cerebral Vascular Disease
Remote Ischemic Conditioning in Acute Ischemic Cerebral Vascular Disease Patients With Coexistence of Cerebral and Coronary Atherosclerosis（RIC-CCCA）
Remote ischemic conditioning(RIC) is a protective systemic strategy by organs brief and sublethal ischemia to confer protection from subsequent severe ischemia in distant organs, especially for heart and brain.
- Trial name
- NCT03721692
- Testing
- RIC
- Where
- China
- Volunteers
- 392 people
- Sponsor
- Capital Medical University
Ischemic Cerebrovascular Disease
Limb Remote Ischemic Conditioning and Cerebrovascular Reserve
Cerebrovascular reserve (CVR), defined as the increase in cerebral blood flow (CBF)in response to a vasodilatory stimulus, is known to reflect the compensative capacity of the brain to maintain adequate blood flow in the face of…
- Trial name
- NCT03589053
- Testing
- Limb remote ischemic conditioning, Control group
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Capital Medical University
Lung Transplant Infection, Lung Transplant Rejection
Clinical Significance of Community-acquired Respiratory Virus Infection and Longitudinal Analysis of the Lung Microbiome in Lung Transplantation
The purpose of this study is to evaluate the clinical significance of community-acquired respiratory virus (CARV) infection in patients with lung transplantation;Explore the lung microbiome dynamics within one year after lung…
- Trial name
- NCT03545919
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Capital Medical University
Gastric Cancer
Study of S-1 Plus DC-CIK for Patients With Advanced Gastric Cancer
The purpose of this study is to evaluate the antitumor effect and safety of clinical effectiveness dendritic cell activated Cytokine induced killer treatment (DC-CIK) plus S-1 based chemotherapy for advanced gastric cancer.
- Trial name
- NCT01783951
- Testing
- DC-CIK, S-1, Cisplatin
- Where
- China
- Volunteers
- 63 people
- Sponsor
- Capital Medical University
GERD, Radiofrequency Ablation
the Efficency and Safety of Stretta in GERD
This study evaluated the efficency and safety of the endoscopic radiofrequency procedure(Stretta) in adult gastroesophageal patients.
- Trial name
- NCT03574831
- Testing
- Stretta
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Capital Medical University
the High-Risk HPV Infection
The Standard Management of HPV Infection
High-risk human papillomavirus (HR-HPV) infection is a necessary condition in the occurence and development of cervical squamous intraepithelial lesion (SIL) and cervical cancer.
- Trial name
- NCT03577925
- Testing
- HPV genotype test
- Where
- China
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- Capital Medical University
Ischemic Stroke
Molecular Mechanisms of microRNA-494 Involving in Cerebral Ischemia
We and other investigations suggested that the activation of nerve cell cycle following cerebral ischemia led to neuronal apoptosis, glial cell proliferation and the formation of glial scar.The cyclin-dependent kinases (CDKs) and…
- Trial name
- NCT03577093
- Testing
- There is no intervention at all.
- Where
- China
- Volunteers
- 600 people
- Sponsor
- Capital Medical University
Stroke, Acute
r-tPA Thrombolytic Therapy in Combination With Remote Ischemic Conditioning for Acute Ischemic Stroke Recovery
to detect the efficiency and safety of intravenous rtPA combined with RIPC in acute ischemic stroke patients
- Trial name
- rtPA-RIC (NCT02886390)
- Testing
- ischemic conditioning
- Where
- 2 sites in China
- Volunteers
- 60 people
- Sponsor
- Capital Medical University
Ischemic Stroke
Rt-PA Thrombolytic Therapy in Combination With Remote Ischemic Conditioning for Acute Ischemic Stroke
The purpose of this study is to determine the safety and feasibility of remote limb ischemic conditioning(RIC) in acute ischemic stroke patients who received r-tPA thrombolytic therapy.
- Trial name
- NCT03231384
- Testing
- Remote ischemic conditioning
- Where
- China
- Volunteers
- 31 people
- Sponsor
- Capital Medical University
Mechanical Ventilation
Decreasing Trigger Sensitivity Could Assist PEEP to Further Improve Regional Ventilation Distribution
In mechanically ventilated patients during supine position, alveolar collapse usually distributes in dependent lung region.Decrease of flow trigger sensitivity might improve homogeneous of tidal volume distribution.
- Trial name
- NCT03241654
- Testing
- flow trigger
- Where
- China
- Volunteers
- 20 people
- Sponsor
- Capital Medical University